Deniz Yuruk's research while affiliated with Mayo Foundation for Medical Education and Research and other places
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Publications (10)
Introduction
Invasive neuromodulation interventions such as deep brain stimulation (DBS) and vagal nerve stimulation (VNS) are important treatments for movement disorders and epilepsy, but literature focused on young patients treated with DBS and VNS is limited. This retrospective study aimed to examine naturalistic outcomes of VNS and DBS treatmen...
Background
Implicit cognitive markers may assist with the prediction of suicidality beyond clinical risk factors. The aim of this study was to investigate neural correlates associated with Death/Suicide Implicit Association Test (DS-IAT) via event-related potentials (ERP) in suicidal adolescents.
Methods
Thirty inpatient adolescents with suicidal...
Background:
Suicide is a leading cause of death in adolescents worldwide. Previous research findings suggest that suicidal adolescents with depression have pathophysiological dorsolateral prefrontal cortex (DLPFC) deficits in γ-aminobutyric acid neurotransmission. Interventions with transcranial magnetic stimulation (TMS) directly address these un...
Background:
The cortical silent period (CSP) and long-interval intracortical inhibition (LICI) are putative markers of γ-aminobutyric acid receptor type B (GABAB)-mediated inhibitory neurotransmission. We aimed to assess the association between LICI and CSP in youths.
Methods:
We analyzed data from three previous studies of youth who underwent C...
Background: Suicide is a leading cause of death in adolescents worldwide. Previous research findings suggest that suicidal adolescents with depression have pathophysiological dorsolateral prefrontal cortex (DLPFC) deficits in γ-aminobutyric acid neurotransmission. Interventions with transcranial magnetic stimulation (TMS) directly address these und...
Aims:
To appraise the current evidence on the efficacy and safety of lamotrigine (LAM) in the treatment of pediatric mood disorders (i.e., Major Depressive disorder [MDD], bipolar disorder [BD]).
Methods:
Major databases were searched for randomized controlled trials (RCTs), open-label trials, and observational studies reporting on pediatric (ag...
Introduction: The Clinical Global Impressions-Improvement (CGI-I) scale is widely used in clinical research to assess symptoms and functioning in the context of treatment. The correlates of the CGI-I with efficacy scales for adolescent major depressive disorder are poorly understood. This study focused on benchmarking CGI-I scores with changes in t...
Citations
... Efficacy of bilateral magnetic stimulation including theta burst stimulation (TBS) in one hemisphere has been explored in randomized control trials (RCT) (Blumberger et al., 2022), in naturalistic studies Kabar et al. Asian Journal of Psychiatry xxx (xxxx) 104013 (Watson et al., 2023) and continue to drive attention from research groups designing new RCTs for special populations (Yuruk et al., 2023). Nevertheless, there is still some uncertainty regarding whether activating the motor cortex adequately correlates to engaging the prefrontal region to ensure the avoidance of subthreshold stimulation intensity that could affect the rates of response and remission (Jannati et al., 2023). ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/11431281202486069-1698870099720_Q64/Juan-Garzon-35.jpg)
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... Кроме того, существуют особые группы риска, которые наиболее уязвимы к проявлениям нежелательных реакций ПЭП. К ним относятся дети и подростки [5,6]. ...
... Attrition was particularly high for posttreatment EEGs due in part to the COVID-19 pandemic. Additionally, while CGI is widely used in psychiatry, there is mixed evidence for its validity (Busner & Targum, 2007;Hedges et al., 2009;Jiang & Ahmed, 2009;Khan et al., 2002), and there are inconsistent links between clinician and patient ratings (Forkmann et al., 2011;Zhang et al., 2022). Clinician judgments are informed by the knowledge of depression's diagnostic criteria; however, their severity ratings are restricted to adolescent disclosures and their observable behaviors. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/511370841071616-1498931717101_Q64/Jeffrey-Mills-3.jpg)
