Dariya Popovych's research while affiliated with I. Horbachevsky Ternopil National Medical University and other places
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Publications (33)
Background. Sympathetic outflow may be capable of selectively increasing or decreasing glomerular capillary pressure and hence glomerular filtration rate (GFR) by differentially activating separate populations of renal nerves. Sympathetic outflow to the kidney is regulated by major cortical, brainstem and medullary areas. The purpose of this study...
Background. Existing methods for assessing glomerular filtration rate (GF) are invasive. Therefore, we set ourselves the goal of evaluating the rate of glomerular filtration by a non-invasive method. Materials and Methods. The object of observations were 10 men aged 37-69 years without clinical diagnosis tested twice with 7-days interval. The rate...
Background. Existing methods for assessing glomerular filtration rate (GF) are invasive. Therefore, we set ourselves the goal of evaluating the rate of glomerular filtration by a non-invasive method. Materials and Methods. The object of observations were 10 men aged 37-69 years without clinical diagnosis tested twice with 7-days interval. The rate...
Background. There are several patented methods of preservation of medicinal waters of the Naftussya type. The authors of the patents as evidence of the correctness of the methods cite the facts of preservation of the ability of canned water to enhance motility rat’s v. portae in vitro and/or increase diuresis. However, such tests are not attributiv...
Background. There are several patented methods of preservation of medicinal waters of the Naftussya type. The authors of the patents as evidence of the correctness of the methods cite the facts of preservation of the ability of canned water to enhance motility rat’s v. portae in vitro and/or increase diuresis. However, such tests are not attributiv...
Background. Balneotherapy has its rightful place in the arsenal of means of treatment of chronic. The universally recognized gold standard of balneofactors is Naftussya bioactive water. The issue of the loss of its healing properties by Naftussya water after extraction from the subsoil, the possibility of its preservation and transportation remain...
Background
The Biopsychosocial (BPS) model is recognized and widely accepted in the field of health care, particularly in rehabilitation. However, in clinical practice the applicability of the BPS model is a challenge for many professionals.
Method
This study aimed to explore the factors that impact the perception of rehabilitation professionals a...
Background. Ergometric physical working capacity (PWC) testing has a long tradition in occupational medicine for assessing whether a sufficiently high level of physical performance for coping with the daily work requirements is given. Physical performance and stress resistance of the body are considered one of the main objects of influence of adapt...
Background. The dramatic events of the Russian-Ukrainian war around the Chornobyl’ nuclear power plant (NPP) once again opened up the healed wound inflicted by radionuclides on the human body not only in Ukraine, but also in Belarus and the border regions of Russia. The drama of the situation was further intensified by the events surrounding the Za...
Nowadays, people's need for fast and effective rehabilitation processes is growing significantly. Sensory devices are available for people with functional disabilities, which are used for rehabilitation to help a person's health and return to an appropriate standard of living. Scientists in the field of rehabilitation medicine are actively studying...
Background. Ergometric physical working capacity (PWC) testing has a long tradition in occupational medicine. PWC can be tested, using performance indicators like VO2max or the mechanical power. However, the calculated by bicycle ergometry PWC in reality reflects the reaction of the autonomic nervous system to muscle load, which, in turn, is strong...
Background. Earlier we showed that the qualitative-quantitative clusters of blood pressure (BP) are very clearly different from each other by age, sex and the constellation of neuro-endocrine, immune and metabolic variables, which we called the Tensioregulome by analogy with the metabolome and the microbiome. The purpose of this study is detailing...
The Biopsychosocial (BPS) model is recognized and widely accepted in the field of health care, particularly in rehabilitation. However, in clinical practice the applicability of the BPS model is a challenge for many professionals.
Method. This study aimed to explore the factors that impact the perception of rehabilitation professionals about the BP...
Background. Earlier we studied the neural, endocrine, immune, microbiome and metabolome accompaniments of quantitative-qualitative blood pressure (BP) clusters of profile patients of Truskavets’ spa. The obtained results give us grounds to put forward the concept of tensioregulome by analogy with the metabolome and the microbiome. The purpose of th...
Background. We have previously shown that nitrogenous metabolites have immunomodulatory effects in healthy rats and humans as well as patients with dysfunction of neuroendocrine-immune complex, encephalopatia and chronic pyelonephritis. The purpose of this study is clarification of the role of neuro-endocrine factors in their immunotropic activity...
Background. Previous studies of the Truskavetsian Scientific School of Balneology have studied the effects of course use of bioactive water Naftussya - the main therapeutic factor of the spa - on plasma levels of thyroid hormones in males and females healthy rats and women with thyroid hyperplasia. In men with chronic cholecystitis, the immediate t...
Background. Earlier we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters “Myroslava” (5 g/L) and “Khrystyna” (10 g/L) have favorable effects on neuroendocrine-immune complex and metabolism of patients with their violations. At the same time, the influence of both waters on one constellation of parameters is sim...
Background. Earlier we studied the neural, endocrine, and metabolic accompaniments of quantitative-qualitative blood pressure (BP) clusters of profile patients of Truskavets’ spa. The purpose of this study is to clarify the immune accompaniment in the same contingent. Materials and methods. Under an observations were 44 patients with chronic pyelon...
Background. Earlier in experiments on rats, it was shown that drinking mineral water, regardless of their mineralization and chemical composition, have similar (nonspecific) course effects on a number of parameters of metabolism and neuroendocrine-immune complex. The aim of this study is to identify such parameters in patients of Truskavets’ spa wh...
Background. Earlier we found effects on the neuroendocrine-immune complex and metabolism, which are common to the mineral waters "Myroslava" and "Khrystyna", instead different from the effects of Naftussya water. The purpose of this article is to find the specific effects of these waters. Materials and Methods. The object of clinical-physiological...
Background. Earlier in an experiment on rats we showed that newly created sulfate-chloride sodium-magnesium drinking mineral waters "Myroslava" and "Khrystyna" of Truskavets’ spa has a significant modulating effects on the parameters of metabolism and the autonomic nervous, endocrine and immune systems. Adhering to the principle "Ex experimento ad...
Background. Earlier we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa have favorable effects on metabolism and neuroendocrine-immune complex of patients with their dysfunction. This report analyzes the effect of balneotherapy on the parameters of the electroencephalogram of the same contin...
Background. Earlier in an experiment on rats, we showed that the newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa have neuroendocrine and metabolic effects significantly different from daily water. Adhering to the principle "From experiment to clinic", we continued research in this direction with the partic...
Background. The immunoneuroendocrinology became the foundation of the Truskavetsian Scientific School of Balneology. The focus of research was on the relationships between EEG and HRV parameters, EEG&HRV and leukocytogram, phagocytosis, cellular and humoral immunity as well as between changes in these parameters under the influence of adaptogenic f...
Background. Earlier, we found relationships between EEG/HRV parameters and plasma/ urine electrolytes concentration in Truskavets’ spa patients. The aim of this study is to analyze the relationships between changes in these parameters under the influence of balneotherapy. Materials and Methods. The object of observation were 22 men (23-70 years), w...
Background. Earlier in an experiment on rats, we showed that newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa has a significant modulating effect on the parameters of metabolism and the autonomic nervous and endocrine systems. In this study, conducted in line with the concepts of neuroendocrine-immune compl...
Background. Drinking mineral water is one of the ethnopharmacologic factors. Previously, we identified the role of organic carbon and nitrogen of mineral waters in their effects on certain metabolic and neuro-endocrine-immune parameters. The purpose of this study is to clarify the role of trace elements of same mineral waters in their effects on ne...
Background. Despite the long history, the results of studies of the impact of balneotherapy in the resort of Truskavets on the lithogenicity of urine are ambiguous, so the topic remains relevant. The aim of this study was to determine the relationship between the lithogenicity index of urine and a number of components of its composition. Materials...
Background. Earlier we found that the newly created sulfate-chloride sodium-magnesium drinking mineral waters of Truskavets’ spa have similar neuroendocrine and metabolic effects on healthy old female rats significantly different from daily water. The aim of this study is to elucidate the effects of these mineral waters on the neuroendocrine status...
Background. Earlier we showed that the balneotherapeutic complex of Truskavets’ spa have significant modulating effects on parameters of EEG&HRV and Immunity of patients with chronic pyelonephritis and cholecystitis in remission accompanied of neuroendocrine-immune complex dysfunction. Were detected the close relationships between EEG, HRV, endocri...
Background. Despite the well-documented relationships between HRV, EEG and anxiety parameters, studies of their sexual dimorphism, judging by the results of the meta-analysis, have so far been conducted separately. The purpose of this study is to clarify sexual dimorphism in almost synchronously registered psycho-neuro-endocrine parameters. Materia...
Background. It has been shown before that drinking mineral waters of different composition has a significant effect on the neuroendocrine, metabolic and immune parameters of healthy rats. We analyzed the canonical correlations between neuroendocrine parameters, on the one hand, and metabolic and immune parameters, on the other hand. Materials and M...
Background. Earlier, we found the multivariant nature of the Popovych’s step test change in children after a course of adaptogenic balneotherapy. In particular, the step test improved in 53,7% of children, remained unchanged in 28,8%, and worsened in 17,5%. The purpose of this study is to identify predictors that allow us to forecast each variation...
Citations
... 2. The regression model, which includes 16 EEG parameters, allows estimating GFR with a standard error of 3,4 mL/min. Such accuracy is not much inferior to that when calculating GFR according to the Cockcroft & Gault formula [13]. ...
... Earlier we showed that the qualitative-quantitative clusters of blood pressure are very clearly different from each other by age, sex and the constellation of neuro-endocrine, immune and metabolic variables [13][14][15][16][17], which we called the Tensioregulome [30] by analogy with the metabolome and the microbiome. The purpose of this study is detailing this concept. ...
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... Earlier we showed that the qualitative-quantitative clusters of blood pressure are very clearly different from each other by age, sex and the constellation of neuro-endocrine, immune and metabolic variables [13][14][15][16][17], which we called the Tensioregulome [30] by analogy with the metabolome and the microbiome. The purpose of this study is detailing this concept. ...
... At the same time, the role of other sex-linked neuro-endocrine factors (gonadotropic hormones and their releasing factors, etc.) and, in particular, the recently discovered sexual dimorphism of a number of EEG parameters in humans is quite likely. 71,72 But even such a limited set of neuro-endocrine parameters allows you to recognize the sex of a rat without examining the genitals with an accuracy of 88% (Fig. 3). ...
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... Normal (reference) values of variables are taken from the database of the Truskavetsian Scientific School of Balneology [19]. For statistical analysis used the software package "Statistica 6.4". ...
... 50,51 So let us limit ourselves to the announcement: Naftussya bioactive water has a modulating effect on the autonomic and central nervous systems, which, in turn, activate phagocytosis, as well as modulate cellular and humoral immunity. 33,[52][53][54][55][56][57][58][59] ...
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... Both groups were equal in terms of gender (4 women each), age (M±SD: 52±15 and 50±10 years), body mass index (26,8±4,2 and 27,8±3,3 kg/m 2 ) as well as of the initial symptoms of urinary syndrome and components of the microbiota of feces, parameters of phagocytosis, metabolism [18,19], as well as autonomous and endocrine status. A fragment of the obtained results was published earlier [18,19], but in order to preserve the integrity of the picture, we consider it necessary to repeat it. ...
... and testosterone (r=-0.03). So, in this specific situation, the relative PSD of VLF band acts as a marker of sympathetic tone and cortisol [52]. In other situation, a decrease in relative PSD of VLF band was accompanied by a decrease in LF/HF (r=0.34) and testosterone level (r=0.26) in combination with an increase in relative PSD of HF (r=-0.60), ...
... Participants. The object of observation in 1997 were 19 men (age 26÷61 years) and 3 women (38,40 and 47 years) with urate urolithiasis and chronic pyelonephritis who were exposed to pathogenic factors of the accident at the Chоrnobylian nuclear power plant during the liquidation of its consequences in 1986-87. According to the documents, the total effective radiation dose was 10÷25 cGy, which is most typical for this contingent [1] [31]. ...
... At the same time, the hypothesis about the role of cytokines in the neurotropic effects of uric acid has the right to be considered. As part of the single project "Nitrogenous metabolites and the neuro-endocrine-immune complex", our laboratory studied the relationship between plasma uric acid and immunity parameters in the same volunteers [16][17][18][19][20][24][25][26][27]31,40]. ...
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