Dahye Moon's research while affiliated with CHA University and other places
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Publication (1)
Oncolytic viruses selectively replicate and destroy cancer cells while sparing normal cells, prompting their recognition as promising antitumor agents. Herpes simplex virus (HSV) is suitable as an anticancer agent, given its considerable therapeutic gene capacity and excellent safety profile in clinical trials. Interleukin (IL)-12 induces a Th1-typ...
Citations
... Once well defined, PDTs and PDHOs could be applied to study the impact of other payloads, such as cytokines and chemokines with a profile that leads to Th1-type immune response mediated by NK, CD4+, and CD8+ T cells (58). These observations can be further complemented on more complex ex vivo models such as patient-derived explants (59), and animal models, to strengthen the use of tumoroids in drug discovery. ...
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