Charles Taieb's research while affiliated with Institut Necker Enfants-Malades and other places
What is this page?
This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
Publications (11)
An improved understanding of the impact of skin cancer on patients’ daily life may optimize disease management. This questionnaire survey of adult patients in real-world settings aimed to assess patient perception of the diagnosis announcement, and the impact of the diagnosis on the patients’ professional and personal life. Data from 355 patients w...
Skin conditions such as acne, atopic dermatitis, skin toxicity from oncology treatment, and scars are among the most common health conditions and negatively impact quality of life (QoL). Yet the physician perception of this impact often varies greatly from the patient perception. This is important because patient illness perception is closely linke...
The aim of this study was to examine the prevalence and nature of fatigue in patients with skin diseases by comparison with controls, using a survey of a large representative sample of the French population (n = 2,502). Of the respondents, 659 reported having a skin disease and 1,843 did not. Quality of life was decreased in people with skin diseas...
Atopic dermatitis has a negative impact on quality of life in patients and their families. However, there have been very few studies of the impact of atopic dermatitis on adolescents and their relatives. The objective of this study was to evaluate the impact of atopic dermatitis in the daily lives of adolescents between 12 and 17 years of age in th...
During menopause, oestrogen deprivation occurs after the end of ovulation, reduction of ovarian hormones and increased androgen levels which trigger skin ageing.1 Skin ageing is associated with an increase in extensibility and a reduction in elasticity. The skin loses its elasticity and becomes more fragile and susceptible to trauma, leading to mor...
Background:
Acne severity and its response to treatment may be influenced by internal and external factors: the exposome.
Objectives:
The aim of this international real-life survey was to assess the most involved exposome factors in acne.
Methods:
11000 individuals, aged between 15 and 39 years, with clinically confirmed acne or without acne,...
Citations
... Physical issues can arise from cancer or its treatment and include clinical signs, symptoms and outcomes or systemic reactions. Pain was the most common physical issue, with a study by Aymonier et al. (2022) revealing that post-surgical scarring-related pain impacted the daily lives of 28.6% of patients with BCC [14]. Other common complaints included itching, erythema, and ulceration. ...
... [2][3][4] Physical and psychosocial sequelae associated with AV include dyschromia, scarring, poor self-image, depression, anxiety, and avoidance of social interaction. 5,6 The pathophysiology of AV is conventionally viewed as resulting from 4 factors occurring at the pilosebaceous unit (PSU): increased sebum, follicular hyperkeratinization, proliferation of Cutibacterium acnes, and inflammation induced by localized immune responses. 5 Collectively, this sequence of pathophysiologic events causes marked inflammation in and around the PSU, which results in visible AV lesions and can ultimately lead to both persistent and post-inflammatory hyperpigmentation (PIH) and/or post-inflammatory erythema (PIE) and various forms of scarring. ...
... One study examined fatigue in patients with rosacea, atopic dermatitis (AD), acne, contact dermatitis and psoriasis and found that the total relative risk of fatigue for all skin diseases were more than four times greater than in a control group. 14 Another study found that almost 50% of patients with psoriasis suffered from considerable fatigue and that fatigue was associated with higher dermatology life quality index (DLQI) scores. 15 Few studies have examined the relationship between HS and fatigue; one study found that around 40% of HS patients had clinically significant fatigue, 16 while another study found that 32% of HS patients reported fatigue as a prodromal symptom preceding inflamed nodules or abscesses. ...
... The subjective symptoms are the effects of daytime pruritus and sleep loss rated on an analog scale of 0 to 10. The tool assesses disease severity with a maximum score of 103 and categorizes the severity as mild (<25), moderate (25-50), or severe (>50) [23]. Both the CBCL 6/18 and the SCORAD index are among the most widely used outcome measurements, allowing for comparisons of the results with other authors' data. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/643904571469824-1530530221271_Q64/Khaled-Ezzedine.jpg)
... However, according to a 2018 study with 1287 women, most health professionals cannot treat and monitor these patients. In this survey, similar to our findings, 50% of women felt that they had not been sufficiently informed about the dermatological symptoms of menopause and 72% reported noticing changes in their skin during perimenopause and menopause [14]. ...
... These data do yet not allow to confirm the hypothesis that SR components impact not only directly the immune responses of the body but also indirectly through modifications of the skin microbiome. 35 While the beneficial and deleterious impact of SR components on inflammatory skin diseases such as atopic dermatitis, psoriasis, and acne has been well described the microbiota may also play a role in the host's immune response during or following exposure to SR. 13,42,44,[106][107][108][109][110][111][112][113][114][115][116][117][118] Investigating the global metabolic profile of the skin regarding the microbiome and UVR, as well as together with other environmental factors such as pollution or climate change, provided interesting and new insights into the dynamics and interactions between the skin metabolome, microbiome, and UVR creating new axes for the development of metabolite-or lipid-based claims to maintain skin health. 119 While, again, there is no direct evidence that UVR has a deleterious impact on the skin microbiome and through this impact causes or worsens existing skin conditions, there is evidence that UVR destroys substances such as porphyrins which are absorbed in the long UVA range and especially in the visible range and which are produced by several microorganisms including the skin commensal Cutibacterium acnes and Pseudomona aeruginosa. ...
