Bruna Gehlen's research while affiliated with University of São Paulo and other places
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Publications (12)
As doenças autoinflamatorias são um novo capitulo fascinante no livro médico. As primeiras páginas foram escritas em 1997, quando dois diferentes consórcios internacionais, de forma independente e paralela, identificaram a associação do gene MEFV com uma doença conhecida há várias décadas: a febre familiar do mediterrâneo. Essa data representou rea...
Citations
... CU is associated with a wide range of comorbidities, including thyroid disease, psychiatric disorders, atopic diseases, rheumatic diseases, inflammatory diseases, osteoporosis, and cancer [47]. A retrospective observational study showed that a longer duration of CSU was associated with a higher frequency of comorbidities (N = 173) [48]. Furthermore, an observational study in Israel that compared patients with (n = 12,778) and without CU (n = 10,714), showed that CU is associated with an increased risk of developing autoimmune disease, particularly in women, with conditions mostly diagnosed during the 10 years after CU diagnosis [49]. ...
![[object Object]](https://i1.rgstatic.net/ii/profile.image/272613410865166-1442007510263_Q64/Rosana-Agondi.jpg)
... A substância é administrada via oral e o mecanismo de ação é determinado pela antagonização dos receptores muscarínicos, promovendo efeitos colinérgicos, o que evidencia o potencial de atravessar a barreira hematocefálica (Gehlen et al., 2021;Amaral et al., 2022). Dentre as principais anti-histáminicos, estão hidroxizina e a prometazina, que são utilizados para promoção de sedação consciente principalmente pacientes pediátricos. ...
... The progressive increase in the number of comorbidities in same patient may support the view that CU is a low-grade systemic inflammatory disease. [20] Netchiporouk et al. assessed comorbidities in children with CU, and they found that atopy was the most common comorbidity (28%); 4.32% of the patients was diagnosed as having autoimmunity; 20% had chronic inducible urticarial (CIndU); and almost 30% had at least one atopic condition. [21] Turk et al. identified four distinct subgroups of CU using machine learning algorithms. ...
Reference: Urticaria and comorbidities
