Brooks B Bond-Watts's research while affiliated with University of California, Berkeley and other places
What is this page?
This page lists the scientific contributions of an author, who either does not have a ResearchGate profile, or has not yet added these contributions to their profile.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
It was automatically created by ResearchGate to create a record of this author's body of work. We create such pages to advance our goal of creating and maintaining the most comprehensive scientific repository possible. In doing so, we process publicly available (personal) data relating to the author as a member of the scientific community.
If you're a ResearchGate member, you can follow this page to keep up with this author's work.
If you are this author, and you don't want us to display this page anymore, please let us know.
Publications (3)
Commercial fermentation processes have long taken advantage of the synthetic power of living systems to rapidly and efficiently transform simple carbon sources into complex molecules. In this regard, the ability of yeasts to produce ethanol from glucose at exceptionally high yields has served as a key feature in its use as a fuel, but is also limit...
The production of fatty acids is an important cellular pathway for both cellular function and the development of engineered pathways for the synthesis of advanced biofuels. Despite the conserved reaction chemistry of various fatty acid synthase systems, the individual isozymes that catalyze these steps are quite diverse in their structural and bioc...
Living systems have evolved remarkable molecular functions that can be redesigned for in vivo chemical synthesis as we gain a deeper understanding of the underlying biochemical principles for de novo construction of synthetic pathways. We have focused on developing pathways for next-generation biofuels as they require carbon to be channeled to prod...
Citations
... coli) and Saccharomyces cerevisiae, are investigated broadly for their capability to create biofuels. E. coli strains can normally use an assortment of carbon sources (counting sugars and sugar alcohols) under both vigorous and anaerobic conditions (Bond-Watts et al. 2013). Different life-forms, for example, Corynebacterium glutamicum and Closteridium species, are additionally effectively utilized in the creation of different biofuels relying upon the idea of the objective material and the kind of biofuel. ...
Reference: Food Wastes for Biofuel Production
![[object Object]](https://i1.rgstatic.net/ii/profile.image/278837377159172-1443491419655_Q64/Miao-Wen-4.jpg)
... The GPP was produced with the introduction of the EfmvaE and EfmvaS genes of Enterococcus faecalis (an acetyl-CoA acetyltransferase/HMG-CoA reductase and an hydroxymethylglutaryl-CoA synthase [74]), and by overexpressing the genes of the mevalonate pathway (ERG12, ERG8, ERG19, and IDI1) [75] and a mutated ERG20 F96W/N127W gene (erg20 * ) that preferentially produces GPP over FPP [76]. Hexanoyl-CoA was produced heterologously using genes from Ralstonia eutropha (RebktB, a β-keto thiolase from Ralstonia eutropha H16 that catalyzes condensation reactions between acetyl-CoA with acyl-CoA molecules [77]), Cupriavidus necator (CnpaaH1, an NADH-dependent 3-hydroxyacyl-CoA dehydrogenase [78]), Clostridium acetobutylicum (Cacrt, a crotonase that catalyzes the dehydration of 3-hydroxybutyryl-CoA to crotonyl-CoA in the n-butanol biosynthetic pathway [79]) and Treponema denticola (Tdter, a trans-enoyl-CoA reductase [80]), or feeding hexanoic acid as a substrate for AAE (encoded by CsAAE1 from Cannabis). Expression of the genes encoding CsTKS and CsOAC produced olivetolic acid, which was prenylated by CsPT4-T, a geranylpyrophosphate:olivetolate geranyltransferase activity. ...
... These three compounds are used for various purposes, ranging from pharmaceutical precursors (BDO and HB) to a drop-in gasoline replacement (n-butanol). [11][12][13] In particular, BDO can be used as a humectant or solvent for a variety of different high-value products, as well as a co-monomer for production of various polymers. These three compounds can also be further dehydrated to produce the C 4 monomers 1,3butadiene (from BDO), 14 methyl vinyl ketone (from HB), 15 and 1butene (from n-butanol). ...
