Arthur Vasilaras's research while affiliated with Chris O’Brien Lifehouse and other places

Publications (32)

Article
Full-text available
Objectives: To determine if early (three months) and late (one year) post-operative continence is improved by performing a novel retropubic vascularised fascial sling (RoboSling) procedure concurrently with robot-assisted radical prostatectomy in men undergoing treatment for localised prostate cancer. To additionally assess surgical outcomes, quali...
Article
Full-text available
Purpose Renal angiomyolipoma (AML) is the most common benign renal tumor. Whilst generally asymptomatic, they can cause life-threatening bleeding. Selective angioembolization (SAE) may be used to treat large symptomatic and asymptomatic AMLs. We aimed to evaluate the efficacy of SAE for symptomatic and asymptomatic renal AMLs and determine characte...
Article
Full-text available
Objective To describe a novel RoboSling technique performed at the time of robot‐assisted radical prostatectomy (RARP) and its utility for enhancing urinary function recovery postoperatively. Materials and Methods The surgical technique involves harvesting a vascularised, fascial flap from the peritoneum on the posterior aspect of the bladder. Fol...
Article
Introduction: Demand for donor kidneys far exceeds the availability of organs from deceased donors. Living donor kidneys are an important part of addressing this shortfall, and laparoscopic nephrectomy is an important strategy to reduce donor morbidity and increase the acceptability of living donation. Aim: To retrospectively review the intraope...
Article
Objectives: To assess the post-operative complication rate and overall survival when bovine pericardium is used as graft material for inferior vena cava reconstructions in patients with renal cell carcinoma. The ideal graft material is yet to be established, with synthetic grafts widely studied and used in the current literature. Methods: We per...
Article
Full-text available
46,XX disorders of sexual development (DSDs) occur rarely and result from disruptions of the genetic pathways underlying gonadal development and differentiation. We present a case of a young phenotypic male with 46,XX SRY-negative ovotesticular DSD resulting from a duplication upstream of SOX9 presenting with a painful testicular mass resulting fro...
Article
A custom CGH microarray that covers the SOX9 regulatory region. Log2 ratio scatterplot showing individual data points. Blue box highlights copy number gain with 3' breakpoint region magnified.
Article
Background: Total cystectomy and subsequent reconstruction of the urinary tract may be required for primary malignancy of the bladder, or in the context of multi-visceral resection for more advanced pelvic tumors. Complications following urinary diversion are a major source of morbidity, particularly in pelvic exenteration (PE) patients. Methods:...
Article
Urine leak following pelvic exenteration for locally advanced pelvic malignancy is a major complication leading to increased mortality, morbidity and length of stay. We reviewed our experience and developed a diagnostic and management algorithm for urine leaks in this patient population. Consecutive patients who underwent en bloc cystectomy and con...
Article
The best technique for anastomosis of the donor ureter remains unresolved and an individual surgeon's preferred technique is likely to be based on training background. This retrospective analysis compares three ureteroneocystostomy techniques in 204 consecutive transplants with an overall ureteric complication rate of 7.3%. Ureteric complications a...
Article
The aim of this study was to assess possible risk factors for urinary leakage of a newly formed urinary conduit after a partial or total pelvic exenteration. An analysis was conducted from prospectively collected data of patients who underwent a pelvic exenteration with conduit formation for advanced and recurrent pelvic cancer. Of 232 patients und...
Article
The aim of this study was to analyse the effect of the right donor kidney and multiple arteries, on donor and recipient outcomes in the era of laparoscopic live donor nephrectomy (LLDN). e retrospectively analysed the 200 donors and recipients who underwent a planned laparoscopic nephrectomy at two hospitals between September 1998 and December 2006...

Citations

... It was associated with lesser analgesic requirements in the post-operative recovery period, a swift return to the daily routine, lower complications rate, and shorter hospital stays. [3][4][5][6][7] However, there are a few inherent challenges while adopting laparoscopic nephrectomy in a new unit. These include a significant learning curve required to adopt this modality. ...
... The RoboSling technique has been developed as a novel method to improve recovery of continence in men undergoing RARP. The RoboSling is a vascularised flap of peritoneum positioned as a sling underneath the urethrovesical junction and then hitched to the pubic bone with dissolvable sutures [12]. The placement of this sling is intended to improve postoperative continence by restoring pelvic/urethral support, maintaining a greater length of urethra exposed to increases in intra-abdominal pressure, and providing outlet resistance. ...
... Infrarenal and retrohepatic clamping of the IVC alongside renal inflow control allows the resection of the tumor and its thrombus on a bloodless surgical field without serious hemodynamic changes by venotomy. However, when the thrombus enters the intrathoracic part of the IVC, defined as level IV, complete control of the IVC harboring the thrombus entails a transthoracic approach and vascular control of renal and liver blood inflow [4,5]. 1 1 1 1 ...
... 69470000-69570000). Заболевание было диагностировано в возрасте 18 лет в связи с острым заболеванием мошонки, причиной которого была овуляция [3]. В нашем случае выявление заболевания стало следст-вием оперативного вмешательства по поводу разрыва овотестикулярной гонады на границе овариального и тестикулярного компонентов. ...
... The 5.2-kb region of overlap has a core gonadal enhancer for SOX9 implicated in both 46,XX and 46,XY DSD (Gonen et al., 2017). eSR-B was identified after four 46,XX SRY-negative sex reversal DSD patients presented with duplications in the upstream regulatory region of SOX9 known as RevSex (Benko et al., 2011;Hyon et al., 2015;Ohnesorg et al., 2017;Vetro et al., 2011;Xiao et al., 2013). eSR-B is the RevSex fragment showing overlap amongst these patients and with a highly conserved SOX9 binding motif (Gonen et al., 2017). ...
... However, PE exacts a considerable toll, as evidenced by a substantial rate of morbidity and mortality [2]. Prior reports indicate an overall complications rate ranging from 24 % to 97 %, coupled with a median hospitalization period of 19 days, with considerable variation spanning from 7 to 84 days [3]. ...
... However, increased serum creatinine and blood urea nitrogen levels have also been described. Therefore, the validity of the drain fluid creatinine-to-serum creatinine ratio (DCSCR) as an initial indicator of urinary leak has been proposed by several authors, with a drain creatinine level just 18% higher than the serum creatinine level can potentially signify a urine leak, although there is no strong evidence in literature to support specific cut-off values or indices [141,142]. Because the diagnosis is often postoperative, other biological markers may be altered showing increased parameters of inflammation and impaired renal function, like what occurs in septic conditions [143,144]. ...
... Nevertheless, it should be noted that most living donors with multiple renal arteries in the reported studies were donors with a maximum of three renal arteries. 47,92,93,[95][96][97][98][99][111][112][113]115,116,[118][119][120][121][122][123]126,128,129,131 Only a minority of the donors with multiple renal arteries had four or more renal arteries. 92,93,95,98,112,113,119,[121][122][123] Moreover, as no literature is available on donors with more than four renal arteries, we cannot draw any definitive conclusions in this regard. ...
... The standard approach to the retroperitoneum is via an oblique incision in the iliac fossa in this unit. End-to-side vascular anastomoses were performed for the renal artery and vein, and a m o d ifi e d L i c h -G r e g o i r t e c h n i q u e w a s u s e d fo r t h e ureterocystostomy (26). Surgical drains were placed in the retroperitoneum at the discretion of the surgeon and were removed when the drain volume was <50 ml in 24 h. ...
... Nevertheless, urinary diversion, while commonplace, is intricately associated with a notably elevated incidence of urological morbidity, ranging from 9 % to 24 %. This encompasses an array of complications such as urinary tract infections (UTIs), urinary sepsis, hydronephrosis, urine leak, anastomotic stricture, and the imperative need for kidney drainage, collectively underscoring the heightened risk of urological complications in the context of PE [5,6]. ...