Alev Yilmaz's research while affiliated with Istanbul University and other places
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Publication (1)
Bakcground
The aim of this study was to evaluate the efficacy and safety of citrate versus heparin anticoagulation for CRRT in critically-ill children.
Methods
This retrospective comparative cohort reviewed the clinical records of critically-ill children undergoing CRRT with either RCA or systemic heparin anticoagulation. The primary outcome measu...
Citations
... In the current issue of Pediatric Research, Atis et al. reported their experience treating 131 critically ill children on CKRT with systemic heparin or regional citrate anticoagulation (RCA) in a tertiary PICU located in Istanbul. 2 Here, we will review the advantages and disadvantages of the two anticoagulant strategies and discuss key points relevant to the study of Atis et al. Systemic unfractionated heparin (UFH) was the first-choice anticoagulant used in the 90 s for CKRT, given the experience available using heparin in hemodialysis, its low cost and efficacy to prevent thrombotic events, and rapid reversal with protamine. ...