Agatha Carina Leite Galvan's research while affiliated with Universidade Federal da Fronteira Sul and other places
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Publications (4)
Early life stress (ELS), characterized as abuse, neglect, and abandonment, can cause several adverse consequences in the lives of affected individuals. ELS experiences can affect an individual’s development in variable ways, persisting in the long term and promoting lasting impacts, considering that early exposure to stressors can be biologically i...
Anxiety and depression are prevalent mental disorders around the world. The etiology of both diseases is multifactorial, involving biological and psychological issues. The COVID-19 pandemic settled in 2020 and culminated in several changes in the routine of individuals around the world, affecting mental health. People infected with COVID-19 are at...
Neuroinflammation is closely related to the development of depression, since the latter is caused, among other factors, by inflammatory processes, mainly related to the activation of microglia and expression of specific genes, which occurs during the neuroinflammatory process. Thus, COVID-19 is an important risk factor for the development of depres...
Citations
... The COVID-19 pandemic created a favorable environment based on social isolation and fear of the unknown. Diagnoses of depression and anxiety have increased significantly in recent years [34]. According to WHO data, there was an increase of at least 25% in cases of depression and anxiety in the first year of the pandemic alone, which may have been even more significant in the following years [35]. ...
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... The purinergic system also can contribute to tissue homeostasis, wound healing, neurodegeneration, inflammatory responses, and pathogenesis of various diseases, such as viral infections (Franciosi et al. 2021). In viral infections, the release of ATP from damaged and infected cells induces a cascade, activating purinergic receptors, enhancing the release of pro-inflammatory mediators, and migrating neutrophils and macrophages to the site of infection (Franciosi et al. 2021, Simões, Galvan et al. 2022. These occurrences confirmed the cooperation between the purinergic and immune systems. ...
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