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Estimating premorbid intelligence Comparison of traditional and contemporary methods across the intelligence continuum

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Abstract

The present investigation compared the North American Adult Reading Test (NAART), Wide Range Achievement Test-3 (WRAT-3) Reading subtest, Barona, and Oklahoma Premorbid Intelligence Estimate Best(OPIE) premorbid intelligence estimates in 64 chronic pain patients across three intelligence ranges. Results for the entire sample revealed that the NAART, Barona, and OPIE Best equations overestimated Wechsler Adult Intelligence Scale – Revised Full Scale IQ (WAIS-R FSIQ), while the WRAT-3 underestimated FSIQ. When the sample was divided into three intelligence ranges, the OPIE more accurately classified individuals with above average intelligence, while the WRAT-3 more accurately classified individuals with below average intelligence. Three methods (NAART, OPIE, and WRAT-3) provided relatively equivalent classifications of individuals in the average intelligence range. The Barona method tended to systematically under- and overestimate FSIQ across the intelligence continuum. These results suggest the potential utility of using different estimation methods for individuals in different IQ ranges, and speak to the need for development of estimation methods that incorporate current reading ability with best performance and demographic variables.

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... This formula displays adequate predictive validity in estimating WAIS-R Full Scale IQ (FSIQ) for individuals in the borderline and average intelligence ranges (Barona et al., 1984). Nonetheless, the Barona index may provide significant under-or overestimates in cases where premorbid IQ is above 120 or below 69 (Barona et al., 1984;Franzen et al., 1997;Griffin et al., 2002). ...
... More recent approaches employ multiple regression equations to predict cognitive performance using both demographic variables and cognitive instruments as predictors (Griffin et al., 2002;Harnett et al., 2004;Ball et al., 2007;Sierra Sanjurjo et al., 2015). For example, the Oklahoma Premorbid Intelligence Estimation (OPIE) estimates premorbid IQ by combining demographic variables (age, education, occupation, and race) with current performance on the WAIS-R (Vocabulary and Picture Completion subtests) (Scott et al., 1997;Griffin et al., 2002). ...
... More recent approaches employ multiple regression equations to predict cognitive performance using both demographic variables and cognitive instruments as predictors (Griffin et al., 2002;Harnett et al., 2004;Ball et al., 2007;Sierra Sanjurjo et al., 2015). For example, the Oklahoma Premorbid Intelligence Estimation (OPIE) estimates premorbid IQ by combining demographic variables (age, education, occupation, and race) with current performance on the WAIS-R (Vocabulary and Picture Completion subtests) (Scott et al., 1997;Griffin et al., 2002). The OPIE showed a wider range of premorbid IQ scores in which no systematic under-or over-estimation was performed compared to other available techniques (Griffin et al., 2002). ...
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The Word Accentuation Test (WAT, Spanish adaptation of the NART) and the Pseudo-Words (PW) Reading subtest from the Battery for Reading Processes Assessment-Revised (PROLEC-R) are measures to estimate premorbid IQ. This study aims to develop demographically calibrated norms for these premorbid measures in a representative sample of the adult Spanish population in terms of age, education, and sex. A sample of 700 healthy participants from 18 to 86 years old completed the WAT and the PW Reading subtest. The effect of age, years of formal education, and sex on WAT total score, PW total score, and time to complete the PW task (PW time) were analyzed. Percentiles and scalar scores were obtained for each raw score according to nine age ranges and individual education levels. The results indicated a significant effect of age and education on the premorbid performance assessed, with no significant effect of sex. Age and education explained from 1.9 to 33.2% of the variance in premorbid IQ variables. Older participants with fewer years of education obtained worse premorbid IQ estimates. This premorbid IQ estimation decline started in the 56–65 age range for WAT total score and PW time, whereas it started in the 71–75 age range for PW total score. This study reports the first demographic-calibrated norms for WAT and PW Reading subtest for Spanish-speaking population. Even though the influence of age and years of education on premorbid IQ measures was confirmed, the PW Reading subtest showed to be more resistant to decline in elderly population than the WAT.
... Introdução capacidades cognitivas pré-mórbidas quando se pretende avaliar a existência, natureza e grau do potencial declínio cognitivo em distintas condições clínicas (e.g., demência, traumatismo craniano, esquizofrenia, depressão, síndrome de Korsakoff e HIV) (Griffin et al., 2002;Powell, Brossart, & Reynolds, 2003;Baade & Schoenberg, 2004). Por este motivo, a estimação da inteligência pré-mórbida (IPM) é considerada crucial na determinação da presença de declínio cognitivo em qualquer avaliação neuropsicológica (e.g., Lezak, Howieson, & Loring, 2004). ...
... Recentemente, aumentando o poder de predição relativamente aos métodos que utilizam apenas uma das fontes de informação anteriormente referidas, foram elaboradas fórmulas de regressão que combinam variáveis demográficas pertinentes com níveis actuais de desempenho cognitivo identificados através do recurso a provas de leitura e a medidas de inteligência (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002;Schoenberg, Duff, Scott, Patton, & Adams, 2006). Uma vertente da conjugação entre níveis actuais de desempenho, variáveis demográficas e fórmulas de regressão utiliza a capacidade de leitura para a estimação da IPM. ...
... Esta metodologia é actualmente a opção mais valorizada por investigadores e clínicos, já que revisões recentes (Matsuoka et al., 2006;Halliday, 2006;The Psychological Corporation, 2001;Mackinnon, Ritchie, & Mulligan, 1999) evidenciam que os resultados em Testes de Leitura se encontram fortemente correlacionados com pontuações em Escalas de Inteligência e, ainda, que a metodologia mais robusta e com maior valor preditivo combina a capacidade de leitura e o actual nível intelectual, identificados por instrumentos de referência (exemplo: WAIS-III; Wechsler, 1997;2008), utilizando fórmulas de regressão com variáveis demográficas pertinentes (Gladsjo, Heaton, Palmer, Taylor, & Jeste, 1999;McGurn, Starr, Tropfer, Pattie, Whitemann, Lemmon, Whalley, & Deary, 2004). Neste contexto, têm sido desenvolvidos diversos instrumentos para a estimação da inteligência pré-mórbida (e.g., Nelson, 1982;Colombo et al., 2000;Halliday, 2006;Matsuoka et al., 2006;Mackinnon, Ritchie & Mulligan, 1999) baseados na capacidade/competência de leitura, já que dados de natureza clínica apontam para a relativa estabilidade desta capacidade na população normal e para a sua maior preservação ou resistência ao dano cognitivo (e.g., Blair & Spreen, 1989;Krull, Sherer, & Adams, 1995;Bright, Jaldow, & Kopelman, 2002;Griffin et al., 2002), incluindo demência (e.g., Starr & Lonie, 2007), traumatismo craniano (e.g., Morris et al., 2005) ou perturbação psiquiátrica (e.g., Mackinnon & Mulligan, 2005). ...
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Na ausência de informação objectiva sobre o nível de funcionamento cognitivo anterior, é essencial uma estimação fiel da inteligência pré-mórbida (IPM) quando se pretende avaliar a existência, natureza e grau de lesões com potencial declínio cognitivo. Trabalhos recentes nesta área interligam a presente capacidade de leitura de palavras irregulares com índices de inteligência actuais e variáveis demográficas, utilizando fórmulas de regressão. A utilidade e uso frequente de testes de estimação da IPM em protocolos de avaliação neuropsicológica justificam a construção de um teste análogo para a população portuguesa. Deste modo, com o propósito de criar um instrumento objectivo de estimação da IPM, foi desenvolvida a primeira versão experimental do TeLPI, constituída por 121 palavras portuguesas que ostentam casos de irregularidade na relação grafema-fone (palavras irregulares), 105 das quais infrequentes e 16 frequentes. O presente estudo apresenta a metodologia de construção do TeLPI, o processo de selecção de itens e os desafios futuros para a concretização da sua versão final.
... Using a variety of word-reading tests, Lucas, Carstairs, and Shores (2003) identified large standard errors of estimate for regression models predicting IQ. Generally speaking, hold-test estimates have been identified as more accurate than demographic-only estimates (e.g., Blair & Spreen, 1989;Bright & van der Linde, 2018;Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). Researchers have also identified that some combinations of word-reading tests and demographic variables perform better for certain ranges of intellectual functioning (e.g., Griffin et al., 2002). ...
... Generally speaking, hold-test estimates have been identified as more accurate than demographic-only estimates (e.g., Blair & Spreen, 1989;Bright & van der Linde, 2018;Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). Researchers have also identified that some combinations of word-reading tests and demographic variables perform better for certain ranges of intellectual functioning (e.g., Griffin et al., 2002). An additional barrier to the use of word reading tests is that estimates may not be interchangeable from test-to-test (McFarlane et al., 2006;Mullen & Fouty, 2014). ...
Article
Objective: The purpose of this study was to evaluate the clinical utility of regression-based formulas for the RBANS indexes in screening for cognitive impairment. Method: A database of neuropsychological test results was created from archival records in a memory assessment clinic. The sample consisted of 83 individuals (37 males/46 females) with an average age of 70.1 (SD = 9.8) and 14.6 years of education (SD = 2.8). Diagnostic accuracy of regression-based predictions provided by Duff and Ramezani (2015) (Duff, K., & Ramezani, A. (2015). Regression-based normative formulae for the Repeatable Battery for the Assessment of Neuropsychological Status for older adults. Archives of Clinical Neuropsychology, 30, 600-604.) and from regression of WTAR standard score were examined via receiver operator characteristic curves. Preliminary generalizability investigation was completed using two additional datasets. Results: The WTAR was found to mediate the relationship between education and all RBANS index scores. The WTAR standard score was also found to contribute uniquely and significantly to the prediction of RBANS performance. Results of diagnostic accuracy analyses showed similar discriminating accuracy for all scores. There was limited support for using the WTAR over demographic variables alone in the estimation of RBANS performance; however, the WTAR was found to be more predictive than education, indicating potential clinical utility to using the word-reading score over just years of attained education. Conclusions: Use of these derived Total Scale score variants is recommended for the screening of cognitive impairment, particularly in individuals with superior or poor educational quality. Further research is required to evaluate the utility of these variations in more diverse samples.
... While there are various approaches to estimating premorbid functioning, the "hold" approach, using reading level, is one of the most widely used in clinical and research settings due to the tests' ease of administration, patient tolerability, and low costs (Barona, Reynolds, & Chastain, 1984;Lezak, Howieson, & Loring, 2004;Schoenberg, Scott, Duff, & Adams, 2002). Tests assessing reading level, which measure the ability to read phonetically irregular words, rely more heavily on previous knowledge than current cognitive functioning , are moderately to strongly correlated with intelligence (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002), are considered temporally stable (Casaletto et al., 2014;Crawford, Parker, Stewart, Besson, & De Lacey, 1989;Harvey et al., 2006;Morrison, Sharkey, Allardyce, Kelly, & McCreadie, 2000;Uttl, 2002), and make use of abilities that are typically only mildly affected by many forms and degrees of cerebral injury or pathology (Casaletto et al., 2014;Green, Melo, Christensen, Ngo, Monette, & Bradbury, 2008;Maddrey, Cullum, Weiner, & Filley, 1996;Patterson, Graham, & Hodges, 1994;Stebbins, Wilson, Gilley, Bernard, & Fox 1990;Willshire, Kinsella, & Prior, 1991). ...
... been generally well established (Crawford, Deary, Starr & Whalley, 2001;Uttl, 2002;Whitney, Shepard, Mariner, Mossbarger, & Herman, 2010), as discussed above, reading tests may be poor predictors of IQ, particularly at high and low extremes (Griffin et al., 2002;Ryan et al., 2008;Sprinks et al., 2009). ...
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Objective: We examined test-retest reliability of the WRAT-3 RR over time in an HIV+ sample of predominantly racial/ethnic minority adults. Method: Participants (N = 88) completed a comprehensive neuropsychological battery, including the WRAT-3 RR, on at least two separate study visits. Intraclass correlation coefficients (ICCs) were computed using scores from baseline and follow-up assessments to determine the test-retest reliability of the WRAT-3 RR across racial/ethnic groups and changes in medical (immunological) and clinical (neurocognitive) factors. Additionally, Fisher's Z tests were used to determine the significance of the differences between ICCs. Results: The average test-retest interval was 58.7 months (SD = 36.4). The overall WRAT-3 RR test-retest reliability was high (r = .97, p < .001) and remained robust across all demographic, medical, and clinical variables (all r's > .92). ICCs did not differ significantly between the subgroups tested (all Fisher's Z p's > .05). Conclusions: Overall, this study supports the appropriateness of word-reading tests, such as the WRAT-3 RR, for use as stable premorbid IQ estimates among ethnically diverse groups. Moreover, this study supports the reliability of this measure in the context of change in health and neurocognitive status and in lengthy inter-test intervals. These findings offer strong rationale for reading as a "hold" test, even in the presence of a chronic, variable disease such as HIV.
... From the error score on this test one can estimate Full Scale IQ [using the formula 127.8 -.78(NAART errors)] ( Blair & Spreen, 1989). Griffin, Mindt, Rankin, Ritchie, and Scott (2002) report that this measure of intelligence is highly correlated (r = .80, p < .001) ...
... with Full Scale IQ as measured with the Wechsler Adult Intelligence Scale-Revised. As such, it is considered to provide a good estimate of overall intellectual ability ( Griffin et al., 2002). For information about the reliabil- ity and validity of the NAART see Uttl (2002). ...
... Neuropsychologists have long used tests of the ability to read phonetically irregular words as a means of estimating premorbid intellectual functioning (Nelson & McKenna, 1975;Nelson & O'Connell, 1978). The primary rationales for this methodology are that such tests are moderately to strongly correlated with intelligence (Blair & Spreen, 1989;Griffin, Mindt, Rankin, Ritchie, & Scott, 2002;Johnstone, Callahan, Kapila, & Bouman, 1996;Nelson & McKenna;Wiens, Bryan, & Crossen, 1993), are highly reliable (Crawford, Parker, Stewart, Besson, & De Lacey, 1989;Uttl, 2002), make use of abilities that are only mildly affected by many forms and degrees of cerebral pathology (Crawford, Parker, & Besson, 1988;Hart, Smith, & Swash, 1986;Maddrey, Cullum, Weiner, & Filley, 1996;Nebes, Martin, & Horn, 1984;O'Carroll & Gilleard, 1986;Willshire, Kinsella, & Prior, 1991), are more resistant to dysfunction compared with open-ended vocabulary procedures (Kendrick, 1964;Nelson & O'Connell, 1978), and are quick, simple, and inexpensive to administer. While criticisms have been levied, such as that word-reading tests may be inappropriate for use in patients experiencing visual or language dysfunction or with limited education (Crawford, Moore, & Cameron, 1992;Crawford et al., 1989), they are still frequently employed. ...
... The WRAT-4, based on its correlation with the WAIS-III FSIQ and VIQ (r ¼ .64 for both; Wilkinson & Robertson), would appear to also acceptably estimate intelligence. Compared with the NAART, WRAT Reading similarly underestimates above-average intelligence, estimates average intelligence equally well, and estimates below-average intelligence more accurately (Griffin et al., 2002;Johnstone et al.). These data have led some to suggest using the WRAT Reading rather than the NAART when estimating premorbid intelligence (Johnstone et al.). ...
Article
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Tests of word-reading ability, such as the North American Adult Reading Test (NAART) and Wide Range Achievement Test (WRAT) Word Reading subtest, are often used by neuropsychologists to estimate premorbid intelligence. However, despite the fundamental basis in reading, little work has been done to calculate or estimate literacy level from NAART performance. Additionally, few prior studies have evaluated the use of word-reading tests in underrepresented populations such as African Americans or individuals with lower socioeconomic status and educational attainment. Finally, while the correlations between the NAART and older editions of the WRAT are known, no study has yet examined the relationship between the NAART and WRAT-Fourth Edition (WRAT-4). The purpose of the current study, then, was to replicate and extend prior research in these areas. NAART and WRAT-4 Word Reading (WRAT4WR) performances were examined in a sample of 173 primarily African American individuals who were HIV-positive and who had an average of fewer than 12 years of education. Analyses revealed a strong correlation between NAART error scores and WRAT4WR raw scores (r = -.866, p < .001). Linear regression was used to establish the predictive equation to estimate WRAT4WR scores from NAART errors. This information allows for determining reading grade-level equivalents based on NAART error scores.
... From the error score on this test one can estimate Full Scale IQ [using the formula 127.8 -.78(NAART errors)] (Blair & Spreen, 1989). Griffin, Mindt, Rankin, Ritchie, and Scott (2002) report that this measure of intelligence is highly correlated (r = .80, p < .001) ...
... with Full Scale IQ as measured with the Wechsler Adult Intelligence Scale-Revised. As such, it is considered to provide a good estimate of overall intellectual ability (Griffin et al., 2002). For information about the reliability and validity of the NAART see Uttl (2002). ...
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Interest in studying the effects of extensive music training on nonmusical perceptual and cognitive abilities has grown in recent years. Here, we present evidence that formal music instruction is associated with superior verbal and visual memory. Participants included 15 highly trained pianists and 21 individuals with little or no formal music training. The groups were comparable in terms of age, gender distribution, and socioeconomic status. Musicians showed superior immediate and delayed recall of word lists and greater use of a semantic clustering strategy during initial list-learning than nonmusicians. They also exhibited superior learning, delayed recall, and delayed recognition for visual designs. Group differences in delayed free recall of both words and designs persisted after controlling statistically for estimated Full Scale IQ. These results suggest that extensive music training is associated with a generalized enhancement of auditory and visual memory functions.
... It is common in clinical practice for neuropsychologists to use a discrepancy between a predicted and an obtained test score to assist in the determination of whether organic impairment or a progressive disease is present. Thus, an accurate estimation of premorbid intelligence is necessary to prevent errors such as under-or overestimation of a patient's level of cognitive decline (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002), and the availability of techniques demonstrating good validity and reliability for predicting premorbid intellectual functioning is a central concern of clinicians. When premorbid ability levels can be reasonably estimated, a diagnosis can be made with confidence, and cognitive rehabilitation programs can be properly designed, monitored, and modified (Reynolds, 1997). ...
... The demographic-based regression method for estimating premorbid ability involves developing a multiple linear regression (MLR) model by employing onlydemographicbased variables (e.g., age, gender, education, ethnicity, and occupation) that are easily obtainable and potentially avoid the effects of current ability levels or neurological injury (Griffin et al., 2002). The approach that combinesthe use of demographic variables and current actual performancealso utilizes MLR to predict scores on an IQ measure. ...
Article
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Statistical prediction of an outcome variable using multiple independent variables is a common practice in the social and behavioral sciences. For example, neuropsychologists are sometimes called upon to provide predictions of preinjury cognitive functioning for individuals who have suffered a traumatic brain injury. Typically, these predictions are made using standard multiple linear regression models with several demographic variables (e.g., gender, ethnicity, education level) as predictors. Prior research has shown conflicting evidence regarding the ability of such models to provide accurate predictions of outcome variables such as full-scale intelligence (FSIQ) test scores. The present study had two goals: (1) to demonstrate the utility of a set of alternative prediction methods that have been applied extensively in the natural sciences and business but have not been frequently explored in the social sciences and (2) to develop models that can be used to predict premorbid cognitive functioning in preschool children. Predictions of Stanford-Binet 5 FSIQ scores for preschool-aged children is used to compare the performance of a multiple regression model with several of these alternative methods. Results demonstrate that classification and regression trees provided more accurate predictions of FSIQ scores than does the more traditional regression approach. Implications of these results are discussed.
... Franzen et al. 1997;Binder et al. 2009). See Griffin et al. (2002) for a comprehensive review and critique of methods of pre-morbid estimation. ...
... In this study, we relied on the performance scores (ratio of total correct responses) from the wide range achievement test (WRAT), which assessed the general learning ability (such as reading recognition, spelling, and arithmetic computation). While some reservations remain, the WRAT is still an effective method to estimate intelligence quotient (IQ) values (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). ...
Article
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Brain functional connectome analysis is commonly based on population‐wise inference. However, in this way precious information provided at the individual subject level may be overlooked. Recently, several studies have shown that individual differences contribute strongly to the functional connectivity patterns. In particular, functional connectomes have been proven to offer a fingerprint measure, which can reliably identify a given individual from a pool of participants. In this work, we propose to refine the standard measure of individual functional connectomes using dictionary learning. More specifically, we rely on the assumption that each functional connectivity is dominated by stable group and individual factors. By subtracting population‐wise contributions from connectivity patterns facilitated by dictionary representation, intersubject variability should be increased within the group. We validate our approach using several types of analyses. For example, we observe that refined connectivity profiles significantly increase subject‐specific identifiability across functional magnetic resonance imaging (fMRI) session combinations. Besides, refined connectomes can also improve the prediction power for cognitive behaviors. In accordance with results from the literature, we find that individual distinctiveness is closely linked with differences in neurocognitive activity within the brain. In summary, our results indicate that individual connectivity analysis benefits from the group‐wise inferences and refined connectomes are indeed desirable for brain mapping.
... Zur Beurteilung und Interpretation der Testergebnisse ist es wichtig, Angaben über das prämorbide Leistungsvermögen der untersuchten Patienten zu haben (Griffin, Mindt, Rankin, Ritchie & Scott, 2002), da sich damit das Ausmaß der Leistungsdefizite besser einschätzten lässt. Dies ist vor allem dann wichtig, wenn der Verdacht besteht, dass eine relative Leistungseinbuße vorliegt, also die erzielten Testergebnisse noch in der Altersnorm liegen, aber das prämorbide Leistungsniveau vermutlich deutlich über der Altersnorm lag. ...
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Neurocognitive disorders play an important role in many mental disorders. They are not only accompanying phenomena, but also depict elementary characteristics of neuropathophysiological changes in many disorders. Neuropsychology and the neuropsychological diagnostics serve to determine and quantify neurocognitive disorders and their effects on activity and participation. However, they can also make a substantial contribution to the development of etiological models of mental illness. The following article describes the historical development of neuropsychology, the methodological approach (lesion-symptom cartography), the importance of cognitive models in neuropsychology, and important developments in modern neuropsychology. Finally, the benefits of neuropsychological evaluation in psychiatry and psychotherapy are discussed.
... Third, the current study used two different versions of the WRAT Reading subtest as its estimate of premorbid intellect, version 3 in the development sample and version 4 in the validation sample. Although it would have been ideal to use the same version of the WRAT Reading subtest, word reading premorbid estimates are highly related (Berg et al., 2016;Bright & van der Linde, 2018;Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). It is also not known if other estimates (e.g., Test of Premorbid Functioning, National Adult Reading Test) would be as effective as predicting premorbid RBANS scores. ...
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Objective: Assessing cognitive change during a single visit requires the comparison of estimated premorbid abilities and current neuropsychological functioning. Although premorbid intellect has been widely examined, premorbid expectations for other cognitive abilities have received less attention. The current study sought to develop and validate premorbid estimates for the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Method: Using demographic variables and an estimate of premorbid intellect, premorbid performance on the RBANS was predicted in a sample of 143 community-dwelling, cognitively intact older adults. Results: On all six Indexes of the RBANS, premorbid intellect was the best predictor of current cognitive functioning, with gender adding to one of the prediction models (R2 = 0.04-0.16, ps < .02). These prediction formulae were then applied to a sample of 122 individuals with amnestic Mild Cognitive Impairment to look for discrepancies between premorbid and current RBANS scores. Despite minimal differences between premorbid and current RBANS scores in the intact sample, large, and statistically significant differences were observed in the impaired sample, especially on the Immediate Memory Index (discrepancy = -29.00, p < .001), Delayed Memory Index (discrepancy = -32.28, p < .001), and Total Scale score (discrepancy = -25.58, p < .001). Conclusion: Although validation in larger samples is needed, the current estimates of premorbid RBANS abilities may aid clinicians in determining change across time.
... There are limitations to the current study that must be acknowledged. We used a test of reading ability to estimate premorbid IQ, which may be affected by multiple factors (Griffin et al., 2002). The study employed performance-based measures of functional capacity and social skills and did not directly assess work, educational, or psychosocial outcomes. ...
Article
Neuropsychological abilities may underlie successful performance of everyday functioning and social skills. We aimed to determine the strongest neuropsychological predictors of performance-based functional capacity and social skills performance across the spectrum of severe mental illness (SMI). Unemployed outpatients with SMI (schizophrenia, bipolar disorder, or major depression; n = 151) were administered neuropsychological (expanded MATRICS Consensus Cognitive Battery), functional capacity (UCSD Performance-Based Skills Assessment-Brief; UPSA-B), and social skills (Social Skills Performance Assessment; SSPA) assessments. Bivariate correlations between neuropsychological performance and UPSA-B and SSPA total scores showed that most neuropsychological tests were significantly associated with each performance-based measure. Forward entry stepwise regression analyses were conducted entering education, diagnosis, symptom severity, and neuropsychological performance as predictors of functional capacity and social skills. Diagnosis, working memory, sustained attention, and category and letter fluency emerged as significant predictors of functional capacity, in a model that explained 43% of the variance. Negative symptoms, sustained attention, and letter fluency were significant predictors of social skill performance, in a model explaining 35% of the variance. Functional capacity is positively associated with neuropsychological functioning, but diagnosis remains strongly influential, with mood disorder participants outperforming those with psychosis. Social skill performance appears to be positively associated with sustained attention and verbal fluency regardless of diagnosis; however, negative symptom severity strongly predicts social skills performance. Improving neuropsychological functioning may improve psychosocial functioning in people with SMI.
... Best performance approaches to estimating premorbid ability are based upon the assumption that the tests in which patients accrue the highest score are likely to reflect relatively intact function, and therefore provide a baseline ability level against which current functioning can be compared. Typically, the clinician infers general premorbid ability on the basis of the one or two best WAIS-IV subtest scores, but given the considerable variability among the subtests observed in healthy populations, it is acknowledged that this approach is likely to significantly overestimate premorbid ability (Franzen et al., 1997;Griffin, Mindt, Rankin, Ritchie, & Scott, 2002;Mortensen, Gade, & Reinisch, 1991;Reynolds, 1997). Some authors have, in response to this problem, developed a "correction" to be applied to such estimates that uses demographic (and other) information, but have not satisfactorily resolved the tendency towards premorbid IQ overestimation (Powell, Brossart, & Reynolds, 2003). ...
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To evaluate impact of neurological injury on cognitive performance it is typically necessary to derive a baseline (or ‘premorbid’) estimate of a patient’s general cognitive ability prior to the onset of impairment. In this paper, we consider a range of common methods for producing this estimate, including those based on current best performance, embedded ‘hold/no hold’ tests, demographic information, and word reading ability. Ninety-two neurologically healthy adult participants were assessed on the full Wechsler Adult Intelligence Scale – Fourth Edition (WAIS-IV; Wechsler, 2008) and on two widely used word reading tests: National Adult Reading Test (NART; Nelson, 1982; Nelson & Willison, 1991) and Wechsler Test of Adult Reading (WTAR; Wechsler, 2001). Our findings indicate that reading tests provide the most reliable and precise estimates of WAIS-IV full-scale IQ, although the addition of demographic data provides modest improvement. Nevertheless, we observed considerable variability in correlations between NART/WTAR scores and individual WAIS-IV indices, which indicated particular usefulness in estimating more crystallised premorbid abilities (as represented by the verbal comprehension and general ability indices) relative to fluid abilities (working memory and perceptual reasoning indices). We discuss and encourage the development of new methods for improving premorbid estimates of cognitive abilities in neurological patients.
... The Mini-international Neuropsychiatric Interview (MINI; Sheehan et al., 1998) and an adapted version of the Addiction Severity Index (ASI; McLellan et al., 1992), assessing last, recent (30 day), and lifetime use of drugs and alcohol, were administered to screen for psychotic symptoms in the SUD sample and current substance abuse in all participants. Reading level and premorbid IQ estimate (Griffin et al., 2002) were ascertained using the Wide Range Achievement Test reading subtest (WRAT-3; Wilkinson, 1993). ...
Article
The Social Attribution Task-Multiple Choice (SAT-MC) tests the ability to extract social themes from viewed object motion. This form of animacy perception is thought to aid the development of social inference, but appears impaired in schizophrenia. The current study was undertaken to examine psychometric equivalence of two forms of the SAT-MC and to compare their performance against social cognitive tests recommended for schizophrenia research. Thirty-two schizophrenia (SZ) and 30 substance use disorder (SUD) participants completed both SAT-MC forms, the Bell-Lysaker Emotion Recognition Task (BLERT), Hinting Task, The Awareness of Social Inference Test (TASIT), Ambiguous Intentions and Hostility Questionnaire (AIHQ) and questionnaire measures of interpersonal function. Test sensitivity, construct and external validity, test-retest reliability, and internal consistency were evaluated. SZ scored significantly lower than SUD on both SAT-MC forms, each classifying ~60% of SZ as impaired, compared with ~30% of SUD. SAT-MC forms demonstrated good test-retest and parallel form reliability, minimal practice effect, high internal consistency, and similar patterns of correlation with social cognitive and external validity measures. The SAT-MC compared favorably to recommended social cognitive tests across psychometric features and, with exception of TASIT, was most sensitive to impairment in schizophrenia when compared to a chronic substance use sample.
... The Wechsler Test of Adult Reading (WTAR) standard score was used as a measure of premorbid IQ, due to its resistance to injury and stability over time in adulthood, compared to other cognitive variables that are affected by brain injury. Level of education, measured by the self-reported number of formally completed years of education, was also included as a predictor in the model, given its frequent use as a proxy for premorbid IQ (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). Education is also established to have a correlation with measures of PCS in that lower education has been found to be associated with higher endorsements of symptoms on measures of PCS (Sullivan, Edmed, Allan, Smith & Karlsson, 2015). ...
Article
Objective: Extant literature has demonstrated that symptoms of postconcussive syndrome (PCS) persist well beyond the expected 3-month post-injury recovery period in a minority of individuals with mild traumatic brain injury (mTBI). Suboptimal performance on validity measures and pre- and post-injury psychosocial stressors - rather than actual mTBI or current cognitive functioning - have been identified as predictors of chronic PCS. Whether premorbid IQ has any influence on chronic PCS has been understudied, in the context of established psychogenic etiologies. Method: The sample included 31 veterans, who underwent mTBI neuropsychological evaluations six or more months post-injury in a VA outpatient neuropsychology clinic. A two-step multiple linear regression was conducted to examine the effects on the outcome variable, PCS (Neurobehavioral Symptom Inventory), of the following predictors: cognitive functioning (Repeatable Battery for the Assessment of Neuropsychological Status; Attention, Immediate Memory, and Delayed Memory Indices), performance validity, depression (Beck Depression Inventory-Second Edition), posttraumatic stress disorder (PTSD Checklist, Civilian Version), quality of sleep (Pittsburgh Sleep Quality Index), pain (Brief Pain Inventory), education, and Premorbid IQ (Wechsler Test of Adult Reading). Results: The overall regression model containing all nine predictor variables was statistically significant. Depression (p < .05) and premorbid IQ (p < .05) were the most salient predictors of chronic PCS; in that lower premorbid IQ and greater endorsed symptoms of depression were associated with higher PCS scores. In Step 2 of the multiple linear regression, the WTAR explained an additional 6.7% of the variance in PCS after controlling for psychosocial stressors and current cognitive ability. Conclusion: The findings support premorbid IQ as a unique and relevant predictor of chronic PCS, with significance variance accounted for beyond education, cognitive functioning, and psychosocial variables. Given the predictive relationship between premorbid IQ and PCS, adapting postconcussive interventions to meet the specific needs of individuals with varying levels of intellect may be important in minimizing ongoing symptomatology.
... Longitudinal studies are probably the best way to address this issue, by measuring cognitive performance before and after a period of life in which cannabis is consumed. Otherwise, in the absence of these possibilities, reading tests have been suggested as a better method because they are able to estimate the general ability before eventual impairment, as opposed to other tests (Griffin, Rivera-Mindt, Rankin, Ritchie, & Scott, 2002). Table 24.3 simplifies methods and conclusions of the principal longitudinal studies on premorbid IQ and cannabis use. ...
Chapter
The chapter focuses on premorbid intellectual quotient (IQ) in cannabis users, one of the most controversial topics in studies on the harmful effects of cannabis use on cognition. We critically reviewed the literature in order to propose a model that would be able to summarize the complex relationship between premorbid IQ and cannabis use, in determining different outcomes. Longitudinal studies that assessed IQ measures before and after cannabis consumption had yielded discordant findings. We, however, observed a relationship between higher premorbid IQ and recreational or discontinued use, while a lower premorbid IQ resulted as a predictor for regular or heavy cannabis use. Using these observations as a starting point, we sustain the hypothesis of a shared genetic vulnerability to psychosis and cannabis use, reflected on premorbid IQ, and able to influence the contact with the substance. In turn, cannabis may be a trigger for psychosis toward this continuum of neurodevelopmental vulnerability.
... After approval from the Beth Israel Deaconess Medical Center Institutional Review Board, staff announced the pilot study to residents and asked each individually about their interest. Eligibility was based on: a DSM-IV diagnosis of schizophrenia or schizoaffective disorder, as determined by chart review; 18 years or older; English as a first language (or were capable of communicating fluently in English); stability of positive symptoms; maintenance antipsychotic medication regimen; presence of social and cognitive disability (assessed with the Cognitive Style and Social Cognition Eligibility Scale; Hogarty et al., 2004); an IQ of at least 80 (estimated by the WRAT-4 reading test) (Griffin et al., 2002); and for whom staff indicated no medical contraindications (Hogarty et al., 2004;Hogarty and Greenwald, 2006). Six of the 15 residents met these criteria, gave informed consent to participate, and were enrolled. ...
Article
Objective: This pilot project was designed to develop procedures for and test the feasibility of implementing Cognitive Enhancement Therapy (CET) in a group home environment, with a goal of maximizing treatment efficacy by augmenting social engagement in group CET sessions with ongoing social interaction. Methods: Six participants who met criteria including chronic schizophrenia were recruited in a group home with 30 residents. After two months of CET, pre-and posttest measures, including cognitive tests, were administered and qualitative interviews were conducted periodically. Interaction was observed in the house and staff members were interviewed in a focus group. Results: Five of the initial six participants completed the intervention-which continued for a total of 45 weeks-engaging in weekly group CET sessions and computer exercises outside of the formal sessions. All participants liked the computer exercises, and all but one participated in and reported enjoying the group exercises. Observations and staff comments indicated increased social interaction and sustained impact for some residents. Some aspects of cognitive functioning improved for some participants during the initial two months. Conclusions: CET now needs to be tested more formally to determine if it can be delivered successfully in other group homes with a manualized procedure. The idea should be tested that feedback effects due to the sustained social contact may enhance the effectiveness of CET in group homes and lead to larger, sustained gains in community functioning. Clinicians who provide cognitive interventions should focus attention on the social context in which treatment is delivered and consider providing treatment to patient groups whose daily, ongoing social interaction can enhance its effects.
... Equations from demographic variables in Anglo-Saxon samples (Eppinger, Craig, Adams, & Parsons, 1987;Griffin, Rivera-Mint, Rankin, Ritchie, & Scott, 2002;Powell, Brossart, & Reynolds, 2003) had shown an overestimation in participants with low IQ and underestimation in participants with high IQ. Our analysis of residuals according to IQ range (low, average, high) was consistent with previous research. ...
... As such, reading ability is also correlated with other cognitive domains. Because reading is believed to be relatively resistant to most types of brain injury and disease (Bright, Jaldow, & Kopelman, 2002;Maddrey, Cullum, Weiner, & Filley, 1996;Strauss, Sherman, & Spreen, 2006), reading test performance has been used to estimate preinjury or predisease cognitive functioning (Bright et al., 2002;Green et al., 2008;Griffin, Mindt, Rankin, Ritchie, & Scott, 2002;Paolo, Ryan, Troster, & Hilmer, 1996). ...
... However, given the favorable results, the reported findings should be verified and extended in a larger sample of older stroke patients and those with SAH, or a homogeneous sample of subcortical strokes. Second, the failure to take into account premorbid intelligence may introduce biases such as its confounding effect on PS as well as under-or overestimation of a patient's level of cognitive decline (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). Third, although useful as a screening tool for dementia, the MMSE is sensitive to the brain atrophy (Apostolova et al., 2006;Fjell, Amlien, Westlye, & Walhovd, 2009), but not to the presence of silent brain infarcts and WM lesions (Swirsky-Sacchetti et al., 1992;Vermeer et al., 2003). ...
Article
The association between speed of information processing and cognition has been extensively validated in normal aging and other neurocognitive disorders. Our aim was to determine whether such a relationship exists in stroke. Thirty patients and 30 age- and education-matched healthy individuals were administered a comprehensive battery of neuropsychological tests divided into the following six cognitive domains: processing speed (PS), verbal memory, visual memory, visuoperceptual function, language, and cognitive flexibility. The results demonstrate that stroke patients were characterized by cognitive deficits in almost all of these domains, but have the most pronounced deficits in PS. After adjusting for symbol digit modalities test score, all significant group differences in cognitive functioning disappeared. However, group differences remained significant after controlling for the influence of other cognitive factors. These findings suggest that decreased PS appears to underlie post-stroke cognitive dysfunction and may serve as a potential target for intervention. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
... Equations from demographic variables in Anglo-Saxon samples (Eppinger, Craig, Adams & Parsons, 1987;Griffin, Rivera-Mint, Rankin, Ritchie & Scott, 2002;Powell, Brossart & Reynolds, 2003) Overall, this is the first study to derive regression equations for estimating premorbid intelligence in a large and representative Latin American sample. It provides a way to estimate the IQ from information obtained quickly and reliably, such as years of education and performance on the WAT-R, which is a simple and fast test to implement in any setting. ...
Article
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Spanish is the fourth most spoken language in the world, and the majority of Spanish speakers have a Latin American origin. Reading aloud infrequently accentuated words has been established as a National Adult Reading Test-like method to assess premorbid intelligence in Spanish. However, several versions have been proposed and validated with small and selected samples, in particular geographical conditions, and they seldom derive a formula for IQ estimation with the Wechsler Adult Intelligence Scale (WAIS) Full-Scale IQ (FSIQ). The objective of this study was to develop equations to estimate WAIS-Third Edition (WAIS-III) FSIQ from the Word Accentuation Test-Revised (WAT-R), demographic variables, and their combination within diverse Latin American samples. Two hundred and forty participants from Argentina and Colombia, selected according to age and years of education strata, were assessed with the WAT-R, the WAIS-III, and a structured questionnaire about demographic and medical information. A combined approach including place of birth, years of education, and WAT-R provided the best equation, explaining 76% of IQ variance. These equations could be useful for estimating premorbid IQ in patients with Latin American Spanish as their birth language.
... Other techniques such as using a statistical model designed to estimate premorbid intelligence from demographic variables are also available (Crawford et al., 2001). Although reading tests such as the NART have been shown to yield the most accurate estimates of premorbid IQ, measures combining reading ability, best performance, and demographic variables are needed and have the potential to be more accurate than a test of reading ability used in isolation (Griffin et al., 2002). ...
Article
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Background Mild cognitive impairment (MCI) is a diagnostic classification used to describe patients experiencing cognitive decline but without a corresponding impairment in daily functioning. Over the years, MCI diagnostic criteria have undergone major changes that correspond to advancements in research. Despite these advancements, current diagnostic criteria for MCI contain issues that are reflected in the research literature. Methods A review of the available MCI literature was conducted with emphasis given to tracing MCI from its conceptual underpinnings to the most current diagnostic criteria. A clinical vignette is utilized to highlight some of the limitations of current MCI diagnostic criteria. Results Issues are encountered when applying MCI diagnostic criteria due to poor standardization. Estimates of prevalence, incidence, and rates of conversion from MCI to dementia reflect these issues. Conclusions MCI diagnostic criteria are in need of greater standardization. Recommendations for future research are provided that could potentially bring more uniformity to the diagnostic criteria for MCI and, therefore, more consistency to the research literature.
... Subtest (WRAT-3) as an estimate of IQ (Kremen et al., 2006). Although the WRAT-3 may underestimate full-scale IQ, it tends to be very accurate when used to classify individuals with below average intelligence (Griffin et al., 2002). ...
... Identifying performance that is indicative of subtle decline is challenging and requires appropriate population-based norms or individual baseline performance or both. Because baseline testing from earlier in life is generally lacking, demographically-based prediction equations have been developed to estimate premorbid intellectual levels (e.g., Barona, Reynolds & Chastain, 1984;Crawford et al., 1989;Griffin et al., 2001) [34][35][36]. Duff and colleagues [37,38] have demonstrated that this approach can be extended to estimate premorbid memory abilities based on demographics and a measure of premorbid intellect; they further demonstrated that people with aMCI show significantly greater discrepancies between actual performance and estimated premorbid performance than cognitively healthy peers. Adopting a similar approach, we used linear regression to develop prediction equations to estimate premorbid functioning for each of the aMCI-related factors using a combination of demographic variables (age, gender, race (non-Hispanic Caucasian vs. other) and premorbid intellect. ...
Article
Aim: It is difficult to reliably detect the earliest signs of Alzheimer's disease (AD)-associated cognitive impairment. Our aim was to compare 3 psychometric methods of identifying amnestic mild cognitive impairment (aMCI) in a middle-aged longitudinal cohort enriched for AD risk. Methods: Wisconsin Registry for Alzheimer's Prevention (WRAP) participants with 3 waves of cognitive assessment over approximately 6 years were coded as meeting each of 3 psychometric aMCI definitions: (a) 'aMCI standard-baseline' used published norms to establish cutoffs for baseline performance; (b) 'aMCI robust-baseline' applied WRAP-specific robust norms to baseline, and (c) 'aMCI robust-multiwave' applied these robust norms across 3 waves of assessment. Each group was compared to a cognitively healthy subset. Results: Half the aMCI standard-baseline and one third of the aMCI robust-baseline group reverted to normal ranges at follow-up. Only the aMCI robust-multiwave method had an aMCI × age interaction showing significantly worse age-related memory declines in the aMCI group compared to the cognitively healthy group over 6 years of follow-up. Conclusion: Both cross-sectional methods showed instability over time, with many reverting to normal performance after baseline. The multiwave approach identified a group who showed progressive memory declines over 3 visits. Being able to detect progressive decline in late middle age is a critical step in improving prevention efforts.
... Verbal ability was estimated using the Wide Range Achievement Test (3 rd Edition) (WRAT-3) (Jastak, 1993) because numerous CD participants did not exert adequate effort on the more challenging Wechsler Intelligence Scale for Children (3 rd Edition; WISC-III) or Wechsler Adult Intelligence Scale (3 rd Edition; WAIS-III) Vocabulary subtests originally intended to estimate verbal-conceptual ability (i.e., many refused to complete the tests or did not provide credible answers as test items became difficult). The WRAT-3 has a moderately strong correlation with IQ (Griffin et al., 2002;Strauss et al., 2006). Consistent with previous research (Moffitt, 1993b;Moffitt et al., 1994), verbal ability was significantly lower in CD relative to controls (t 39 =5.09, p<. ...
Article
Emerging research suggests that antisocial behavior in youth is linked to abnormal brain white matter microstructure, but the extent of such anatomical connectivity abnormalities remain largely untested because previous Conduct Disorder (CD) studies typically have selectively focused on specific frontotemporal tracts. This study aimed to replicate and extend previous frontotemporal diffusion tensor imaging (DTI) findings to determine whether noncomorbid CD adolescents have white matter microstructural abnormalities in major white matter tracts across the whole brain. Seventeen CD-diagnosed adolescents recruited from the community were compared to a group of 24 non-CD youth which did not differ in average age (12-18) or gender proportion. Tract-based spatial statistics (TBSS) fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) measurements were compared between groups using FSL nonparametric two-sample t test, clusterwise whole-brain corrected, p < .05. CD FA and AD deficits were widespread, but unrelated to gender, verbal ability, or CD age of onset. CD adolescents had significantly lower FA and AD values in frontal lobe and temporal lobe regions, including frontal lobe anterior/superior corona radiata, and inferior longitudinal and fronto-occipital fasciculi passing through the temporal lobe. The magnitude of several CD FA deficits was associated with number of CD symptoms. Because AD, but not RD, differed between study groups, abnormalities of axonal microstructure in CD rather than myelination are suggested. This study provides evidence that adolescent antisocial disorder is linked to abnormal white matter microstructure in more than just the uncinate fasciculus as identified in previous DTI studies, or frontotemporal brain structures as suggested by functional neuroimaging studies. Instead, neurobiological risk specific to antisociality in adolescence is linked to microstructural abnormality in numerous long-range white matter connections among many diverse different brain regions.
... The Frontal Systems Behavior Scale® (FrsBe; (Malloy & Grace, 2005) and the Behavior Rating Inventory of Executive Function® (BRIEF; (Gioia, Isquith, Guy, & Kenworthy, 2000) were added as informant-based measures of day-to-day executive functioning and behavior. Trail-making (Reitan & Wolfson, 1985) and Stroop interference Lezak, 2004) were added as comparison tasks drawn from the traditional neuropsychological literature, and the Wide Range Achievement Test (WRAT-4) Reading subject was added as a proxy for verbal intelligence (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). Three alternate forms were created for all measures. ...
Article
Executive functioning is widely targeted when human cognition is assessed, but there is little consensus on how it should be operationalized and measured. Recognizing the difficulties associated with establishing standard operational definitions of executive functioning, the National Institute of Neurological Disorders and Stroke entered into a contract with the University of California-San Francisco to develop psychometrically robust executive measurement tools that would be accepted by the neurology clinical trials and clinical research communities. This effort, entitled Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (EXAMINER), resulted in a series of tasks targeting working memory, inhibition, set shifting, fluency, insight, planning, social cognition and behavior. We describe battery conceptualization and development, data collection, scale construction based on item response theory, and lay the foundation for studying the battery's utility and validity for specific assessment and research goals. (JINS, 2013, 19, 1-9).
... The NAART consists of 61 words with irregular spellings that participants are required to pronounce correctly. WAIS-R Full-scale IQ estimates (eFSIQ) are obtained; however, performance is highly correlated with WAIS-R Verbal IQ, (31) (33)(34)(35)(36)(37)(38) which is heavily dependent upon crystallized knowledge and educational achievement (i.e., quality of education). The NAART is also generally resistant to age, gender, and ethnicity. ...
Article
Objectives: Memory evaluation is a key component in the accurate diagnosis of cognitive disorders.One memory procedure that has shown promise in discriminating disease-related cognitive decline from normal cognitive aging is the New York University Paragraph Recall Test; however, the effects of education have been unexamined as they pertain to one's literacy level. The current study provides normative data stratified by estimated quality of education as indexed by irregular word reading skill. Method: Conventional norms were derived from a sample (N = 385) of cognitively intact elderly men who were initially recruited for participation in the PREADViSE clinical trial. A series of multiple linear regression models were constructed to assess the influence of demographic variables on mean NYU Paragraph Immediate and Delayed Recall scores. Results: Test version, assessment site, and estimated quality of education were significant predictors of performance on the NYU Paragraph Recall Test. Findings indicate that estimated quality of education is a better predictor of memory performance than ethnicity and years of total education. Normative data stratified according to estimated quality of education are presented. Discussion: The current study provides evidence and support for normativedata stratified by quality of education as opposed to years of education.
... The estimation of premorbid ability is a critical component of clinical psychological and clinical neuropsychological evaluation (Griffin, Mindt, Rankin, Ritchie, & Scott, 2002). Clinicians often need to make a determination of the extent and pervasiveness of deterioration relative to an individual's preinjury cognitive functioning (Lezak, Howieson, & Loring, 2004). ...
Article
Some research suggests the National Adult Reading Test (NART) may be impaired by traumatic brain injury (TBI). To investigate this, a prospective, longitudinal study included 214 Australian TBI participants given the NART within 1 month post-injury, and at 6 and 12 months. TBI severity, age, education, sex, and mood (HADS) were examined, and significant improvement in NART- estimated full-scale IQ (FSIQ) was noted over time (p < .001). A three-way interaction of time, severity, and age showed younger and middle-aged mild TBI sub-groups improved significantly between 1 and 6 months post-injury, and the older sub-group between 6 and 12 months. In severe TBI, significant NART-estimated FSIQ improvement was noted only for the middle-aged and only between 6 and 12 months post-TBI. NART administration soon after TBI underestimated premorbid IQ, with a complex relationship between time post-injury, severity, and age. Participants with a longer education had higher NART FSIQs, although those with less education gained more IQ points between initial and 6 months assessments suggesting higher initial NART impairment. Regression equations predicted NART FSIQ at 6 (R = 0.813) and 12 months post-trauma (R = 0.792-0.845), their effectiveness being confirmed via cross-validation. No significant relationships were noted between NART-estimated FSIQ and mood variables, or evidence of significant gains in estimated FSIQ between 12 and 24 months post-injury.
... Reading ability, as a correlate of both education and intelligence, is also related to neuropsychological test performance. Reading is believed to be relatively resistant to the effects of brain injury and disease (Bright et al. 2002;Maddrey et al. 1996;Strauss et al. 2006); thus, reading test performance has been used to estimate pre-injury or pre-disease cognitive functioning (Bright et al. 2002;Green et al. 2008;Griffin et al. 2002;Paolo et al. 1996). The relation between reading test scores and cognitive functioning is presented in Fig. 32.12. ...
Chapter
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Deficit measurement is the sine qua non of neuropsychology. The risk, of course, is that we can be so focused on deficit measurement – and so focused on describing the nature and severity of a person’s cognitive impairment – that we can underappreciate human diversity and overattribute low or unexpected test scores to brain injury or disease. The North American psychometric tradition has long since attempted to minimize possible misattribution of low test scores through a reliance on the normal curve. However, clinicians know that overly formulaic reliance on the normal curve can result in false positive and false negative attributions of cognitive diminishment. Moreover, the normal curve relates to a single test score in relation to a theoretical normal population. Neuropsychologists never rely on single tests. Instead, we administer numerous tests and we interpret performance in combination, not in isolation. Thus, the principles of normative test score interpretation, applied to single test scores, are inherently limited when interpreting performance across a battery of tests.
... Word reading tests are used to estimate premorbid intelligence because word reading correlates highly with IQ in healthy adults and is relatively resistant to decline in patients with various brain disorders. 15 Thus, reading literacy represents a baseline from which cognitive changes can be judged. The difference between reading literacy and higher-order cognitive abilities scores is used as an estimate of cognitive change. ...
Article
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Aim and method The present university-based outpatient clinic, cross-sectional study assessed cognitive performance in a sample of 137 adults, with the primary objective of determining differences in cognitive performance as a function of gender and hypertension status in a type 2 diabetes cohort.Results Approximately 64% of the sample was 65 years old and younger, and 50 subjects had > 13 years of education. Global mental ability scores were relatively similar by age grouping, and higher-ordered cognitive functioning and reading literacy were strongly correlated, r (98) = 0.62, P < 0.01. Approximately 30% of the sample posted global mental ability scores in the slow learner range on tasks measuring attention, immediate memory and verbal reasoning. Males achieved higher cognitive functioning scores compared to females on multiple mental ability tasks. The presence of hypertension was associated with significantly worse cognitive performance compared to those subjects without hypertension, t = 2.11, P = 0.03. Approximately 57% of the hypertension group was classified as mild cognitive impaired.Conclusion While approximately half of the general population can be expected to demonstrate an average range of performance on cognitive ability measures, such an expectation could be inappropriately generalised to persons diagnosed with type 2 diabetes, even among those who were high school educated.
... Results using this method of comparison have been decidedly mixed, with no one method proving superior. All methods of estimating the preexisting neuropsychological skill level from individual data suffer regression to the mean (Baade & Schoenberg, 2004;Ball et al., 2007;Griffin et al., 2002;Langeluddecke & Lucas, 2004;Powell et al., 2003;Spinks et al., 2009;Yates, 1956). ...
Article
Conventional neuropsychological norms developed for monolinguals likely overestimate normal performance in bilinguals on language but not visual-perceptual format tests. This was studied by comparing neuropsychological false-positive rates using the 50th percentile of conventional norms and individual comparison standards (Picture Vocabulary or Matrix Reasoning scores) as estimates of preexisting neuropsychological skill level against the number expected from the normal distribution for a consecutive sample of 56 neurologically intact, bilingual, Hispanic Americans. Participants were tested in separate sessions in Spanish and English in the counterbalanced order on La Bateria Neuropsicologica and the original English language tests on which this battery was based. For language format measures, repeated-measures multivariate analysis of variance showed that individual estimates of preexisting skill level in English generated the mean number of false positives most approximate to that expected from the normal distribution, whereas the 50th percentile of conventional English language norms did the same for visual-perceptual format measures. When using conventional Spanish or English monolingual norms for language format neuropsychological measures with bilingual Hispanic Americans, individual estimates of preexisting skill level are recommended over the 50th percentile.
... Verbal ability was estimated using the Wide Range Achievement Test (3 rd Edition) (WRAT-3) (35) because numerous CD participants did not exert adequate effort on more challenging WISC-III/WAIS-III Vocabulary subtests originally intended to estimate verbalconceptual ability. WRAT-3 is strongly correlated with verbal IQ (36,37). Consistent with previous research (38,39), CD verbal ability was significantly lower compared to controls (t 39 =5.09, p<.001). ...
Article
Studies of pediatric conduct disorder (CD) have described frontal and temporal lobe structural abnormalities that parallel findings in antisocial adults. The purpose of this study was to examine previously unexplored cortical thickness and folding as markers for brain abnormalities in "pure CD"-diagnosed adolescents. On the basis of current frontotemporal theories, we hypothesized that CD youth would have thinner cortex or less cortical folding in temporal and frontal lobes than control subjects. We obtained T1-weighted brain structure images from 24 control and 19 CD participants aged 12 to 18 years, matched by gender and age. We measured group differences in cortical thickness and local gyrification index (regional cortical folding measure) using surface-based morphometry with clusterwise correction for multiple comparisons. The CD participants, compared with control subjects, showed both reduced cortical thickness and folding. Thinner cortex was located primarily in posterior brain regions, including left superior temporal and parietal lobes, temporoparietal junction and paracentral lobule, right superior temporal and parietal lobes, temporoparietal junction, and precuneus. Folding deficits were located mainly in anterior brain regions and included left insula, ventro- and dorsomedial prefrontal, anterior cingulate and orbitofrontal cortices, temporal lobe, right superior frontal and parietal lobes, and paracentral lobule. Our findings generally agree with previous CD volumetric studies but here show the unique contributions of cortical thickness and folding to gray matter reductions in pure CD in different brain regions.
... A major limitation for the use of psychometric instruments not calibrated and validated for the Portuguese population is the impossibility of adopting cutoff points extracted from an originally studied population. To overcome this difficulty, we decided to perform an intra-individual comparison between the values found in each domain of the neurocognitive battery and the cognitive abilities of their premorbid state [8,[25][26][27] derived from the WAIS-R. The method chosen to accomplish this was first described by Barona et al. [28] and has been used in multiple previous studies including HIV-infected populations [29][30][31]. ...
Article
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This study focused on neurocognitive disorders associated with HIV infection, characterizes the most affected neuropsychological domains and their potential as factors related with depression. 130 HIV-positive individuals with CD4 >200 cells/mm(3), undetectable viral load, treated with HAART and with all kinds of risk behaviors were included. A structured interview composed by seven sections was used and relevant clinical and laboratory data was assessed. For the neuropsychological and depression assessment the HIV Neurobehavioral Research Center (HNRC) Battery and Hamilton Rating Scale for Depression (HAM-D) were chosen. Univariate nonparametric statistics and multivariate regression model were performed. Among 34% of depressed subjects, 20.7% had attempted suicide, 45.4% were under psychiatric medication and only 19% had no diagnostic criteria for HIV Associated Neurocognitive Disorders (HAND). The effect of depression on cognitive function revealed a significant deterioration in five of the eight measures. In the multivariate analysis, five variables significantly determined depression: sex, social class, antidepressant medication, history of suicide attempt and Dexterity and motor speed (neuropsychological test battery). Despite good patient adherence to treatment (HAART and antidepressive) and good immune status, the prevalence of HAND and depression are high and suggest a significant relation between severity of depression and cognitive functioning.
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A par de uma tendência global, o aumento de idosos dementes com quadros de agitação patológica e oposição aos cuidados é uma realidade crescente em Portugal. Contexto onde a enfermagem proporciona cuidados de proximidade relacional em espaços de intimidade e instrumenta os procedimentos numa sintonia emocional comunicativa, fina e subtil, trabalhando com as pessoas dementes a sua autonomia para aderirem aos cuidados e realizarem as atividades por si mesmas participando na sua própria aprendizagem procedimental, maximizando potencialidades restantes, minimizando dependências e prevenindo complicações, isto é, promovendo a relação de cuidados à altura da dignidade humana. No entanto, a ação dos enfermeiros indica, por vezes, uma tendência para o afastamento do essencial relacional, tanto em favor dos princípios da economia e da tecnologia, como pela não utilização de modos de cuidar que o proporcionem. Em França, a Metodologia de Cuidados Humanitude Gineste Marescotti (MGM) revelou ser uma resposta válida. Diminuiu os quadros de agitação e oposição aos cuidados das pessoas dementes, promovendo-lhes uma postura ativa, melhorando também a satisfação profissional dos cuidadores e reduzindo significativamente a taxa de absentismo devido a lesões músculo-esqueléticas e burnout. Efeitos que motivaram o primeiro estudo científico sobre o método desenvolvido em Portugal, base da elaboração desta obra que levou Gineste e Marescotti a expressarem: Notre rencontre avec Mário Simões fût salutaire. Son désir d'apprendre, sa curiosité l'emmène à investiguer davantage et il nous fait l'honneur d'explorer la philosophie de l'Humanitude pour développer sa thèse de doctorat. Mais c'est aussi avec d'autres précurseurs Nídia, Rafael, João que le Portugal va s'ouvrir à ce prendre soin qui nous unis dans la tendresse. Nous vous remercions pour la confiance que vous nous accordez et nous souhaitons à chacun des lecteurs une belle route sur les chemins de l'Humanitude. Rosette Marescotti et Yves Gineste Concepteurs Philosophie de l'Humanitude
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Background Heavy smokers perform worse on neuropsychological assessment than age‐matched peers. However, traditional pulmonary measures of airflow limitation and hypoxemia explain only a modest amount of variance in cognition. The current objective was to determine whether carotid artery stiffness is associated with cognition in former smokers beyond the effects of amount of smoking and pulmonary function. Methods and Results Eighty‐four former smokers including individuals across a spectrum of airflow limitation severity were included: 30 without chronic obstructive pulmonary disease (Global Initiative for Chronic Obstructive Lung Disease [GOLD] 0 with normal spirometry and lung computed tomography), 31 with mild‐moderate chronic obstructive pulmonary disease ( GOLD 1–2), and 23 with severe‐very severe chronic obstructive pulmonary disease ( GOLD 3–4). Participants completed questionnaires, spirometry, carotid ultrasonography, and neuropsychological testing. Multiple linear regression was used to determine whether carotid artery stiffness is associated with neuropsychological performance in 4 cognitive domains after adjusting for age, sex, pack‐years of smoking, estimated premorbid intellectual functioning, and airflow limitation. Higher carotid artery β‐stiffness index was associated with reduced executive functioning‐processing speed in the fully adjusted model (β=−0.49, SE =0.14; P =0.001). Lower premorbid intellectual function, male sex, and presence of airflow limitation ( GOLD 1 or 2 and GOLD 3 or 4) were also associated with worse executive functioning‐processing speed. β‐Stiffness index was not significantly associated with performance in other cognitive domains. Conclusions Carotid artery stiffness is associated with worse performance on executive functioning‐processing speed in former smokers beyond the effects of aging, amount of past smoking, severity of airflow limitation, and hypoxemia. Future research should examine whether carotid stiffness can be used to identify former smokers at risk for subsequent cognitive impairment.
Article
Psychotic patients with a lifetime history of cannabis use generally show better cognitive functioning than other psychotic patients. Some authors suggest that cannabis-using patients may have been less cognitively impaired and less socially withdrawn in their premorbid life. Using a dataset comprising 948 patients with first-episode psychosis (FEP) and 1313 population controls across 6 countries, we examined the extent to which IQ and both early academic (Academic Factor [AF]) and social adjustment (Social Factor [SF]) are related to the lifetime frequency of cannabis use in both patients and controls. We expected a higher IQ and a better premorbid social adjustment in psychotic patients who had ever used cannabis compared to patients without any history of use. We did not expect such differences in controls. In both patients and controls, IQ was 3 points higher among occasional-users than in never-users (mean difference [Mdiff] = 2.9, 95% CI = [1.2, 4.7]). Both cases and control daily-users had lower AF compared to occasional (Mdiff = -0.3, 95% CI = [-0.5; -0.2]) and never-users (Mdiff = -0.4, 95% CI = [-0.6; -0.2]). Finally, patient occasional (Mdiff = 0.3, 95% CI = [0.1; 0.5]) and daily-users (Mdiff = 0.4, 95% CI = [0.2; 0.6]) had better SF than their never-using counterparts. This difference was not present in controls (Fgroup*frequency(2, 2205) = 4.995, P = .007). Our findings suggest that the better premorbid social functioning of FEP with a history of cannabis use may have contributed to their likelihood to begin using cannabis, exposing them to its reported risk-increasing effects for Psychotic Disorders.
Article
Detection of cognitive impairment and dementia (CID) through the use of brief cognitive assessment tools (BCATs) is the first step to establishing an accurate diagnosis and care plan for individuals seen in primary practices. While the cognitive-behavioral syndrome and underlying etiology may not be readily apparent through brief assessment, clinicians can refer patients for a more comprehensive neuropsychological evaluation. A timely diagnosis maximizes the potential for patients to be involved in decision-making and planning for their future, and allows for expedited intervention and harm reduction. This activity provides a practical review of validated and standardized BCATs that can aid in the detection of CID; reviews cognitive and neuropsychological domains and their clinical relevance; and delineates circumstances for referral to neuropsychology and the utility of neuropsychological evaluation to practicing clinicians.
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This paper reports on the association between intellectual functioning and lifetime homelessness duration among 172 homeless adults with mental illness in Toronto, Canada. Using a standardized test of intellectual functioning, we created two groups: individuals with borderline or lower intellectual functioning (16%) and individuals with above borderline intellectual functioning (84%). Lifetime homelessness duration was approximately three years longer, or almost twice as long, for individuals with borderline or lower intellectual functioning. Implementing more systematic strategies for identifying and supporting individuals with cognitive impairments may hasten transitions out of homelessness for this population. Brief intellectual functioning assessment tools are available.
Article
Cognitive decline assessment implies measuring discrepancies between the subject's previous (premorbid) and the current levels of functioning. However, this information is rarely available and clinicians have to infer it by using indirect methods. This article provides an historical overview of the different methods that have been developed for premorbid intelligence estimation, from the first qualitative methods to the most recent quantitative approaches. The discussion sustains that the most valid methods for premorbid intelligence estimation are those that combine current level of the subject's performance and demographic variables in regression formulas. The constant development of premorbid estimation methods with increasing validity is suggestive of the importance that this measure has for psychological assessment.
Article
The diagnostic specificity of poor premorbid intelligence is controversial. We explored premorbid intelligence level in psychiatric patients with personality disorders, depressive disorders, bipolar disorders and schizophrenic disorders. 273 consecutively admitted patients and 81 controls were included in the study and tested with the ‘Test di Intelligenza Breve’, an Italian adaptation of the National Adult Reading Test. Significant differences between the clinical samples and the control subjects were found but not among the 4 clinical groups. The observation of premorbid IQ deficits in subjects with diagnoses other than schizophrenia suggests a common vulnerability diathesis, which is most likely to have a neurodevelopmental basis.
Article
Searching for a neurobiological understanding of human intellectual capabilities has long occupied those very capabilities. Brain gyrification, or folding of the cortex, is as highly evolved and variable a characteristic in humans as is intelligence. Indeed, gyrification scales with brain size, and relationships between brain size and intelligence have been demonstrated in humans [1-3]. However, gyrification shows a large degree of variability that is independent from brain size [4-6], suggesting that the former may independently contribute to cognitive abilities and thus supporting a direct investigation of this parameter in the context of intelligence. Moreover, uncovering the regional pattern of such an association could offer insights into evolutionary and neural mechanisms. We tested for this brain-behavior relationship in two separate, independently collected, large cohorts-440 healthy adults and 662 healthy children-using high-resolution structural neuroimaging and comprehensive neuropsychometric batteries. In both samples, general cognitive ability was significantly associated (pFDR < 0.01) with increasing gyrification in a network of neocortical regions, including large portions of the prefrontal cortex, inferior parietal lobule, and temporoparietal junction, as well as the insula, cingulate cortex, and fusiform gyrus, a regional distribution that was nearly identical in both samples (Dice similarity coefficient = 0.80). This neuroanatomical pattern is consistent with an existing, well-known proposal, the Parieto-Frontal Integration Theory of intelligence [7], and is also consistent with research in comparative evolutionary biology showing rapid neocortical expansion of these regions in humans relative to other species. These data provide a framework for understanding the neurobiology of human cognitive abilities and suggest a potential neurocellular association.
Article
Background: Depression and diabetes commonly co-occur; however, the strength of the physiological effects of diabetes as mediating factors towards depression is uncertain. Method: We analyzed extensive clinical, epidemiological and laboratory data from n = 2081 Mexican Americans aged 35-64 years, recruited from the community as part of the Cameron County Hispanic Cohort (CCHC) divided into three groups: Diagnosed (self-reported) diabetes (DD, n = 335), Undiagnosed diabetes (UD, n = 227) and No diabetes (ND, n = 1519). UD participants denied being diagnosed with diabetes, but on testing met the 2010 American Diabetes Association and World Health Organization definitions of diabetes. Depression was measured using the Center for Epidemiological Studies - Depression (CES-D) scale. Weighted data were analyzed using dimensional and categorical outcomes using univariate and multivariate models. Results: The DD group had significantly higher CES-D scores than both the ND and UD (p ⩽ 0.001) groups, whereas the ND and UD groups did not significantly differ from each other. The DD subjects were more likely to meet the CES-D cut-off score for depression compared to both the ND and UD groups (p = 0.001), respectively. The UD group was also less likely to meet the cut-off score for depression than the ND group (p = 0.003). Our main findings remained significant in models that controlled for socio-demographic and clinical confounders. Conclusions: Meeting clinical criteria for diabetes was not sufficient for increased depressive symptoms. Our findings suggest that the 'knowing that one is ill' is associated with depressive symptoms in diabetic subjects.
Article
Research has suggested that sustaining a traumatic brain injury (TBI) may increase one’s risk of developing Dementia of the Alzheimer’s Type (DAT) later in life. Several neuropathological models have been proposed to explain the association between TBI and DAT and studies using a neuropsychological deficit profile methodology suggest that the pattern and extent of cognitive decline associated with these conditions are similar. This paper presents a new conceptual model, derived from deficit profile methodology, regarding the relationship between TBI and DAT. This model proposes that, for some individuals, TBI may not lead to true DAT neuropathology, but rather produces a profile of neuropsychological deficits similar to DAT, which increasingly mimics the symptoms of true DAT as the TBI survivor ages. Understanding how TBI may contribute to the development of DAT has important social and medical implications, influencing the direction of prevention efforts and contributing to one’s understanding of DAT.
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When processing music stimuli, most people show a global bias (e.g., Evers et al., 1999). Extensive music training, however, develops both global (Halpern & Bower, 1982) and local (Burton et al., 1989) music processing abilities. Our goal was to determine whether enhancement of musicians' local processing abilities is domain-specific or extends to processing nonmusical, visual stimuli. Musicians outperformed nonmusicians on the Group Embedded Figures Test (Experiment 1) and on Block Design (Experiment 2). Additionally, musicians' ability to copy drawings of physically impossible objects accurately was also superior to that of nonmusicians (Experiment 2). These effects could not be accounted for by group differences in several demographic indicators (age, education, gender, or SES), or (in Experiment 2) in verbal intelligence. The results provide converging evidence that extensive music training is specifically associated with superior visual processing of local details, beyond any benefits it may have on verbal intelligence.
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STOESZ, JAKOBSON, KILGOUR, AND LEWYCKY (2007) and Jakobson, Lewycky, Kilgour, and Stoesz (2008) examined whether music training is associated with nonmusical abilities. They concluded that their results provided evidence of "specific" associations between music training and local-processing abilities (Stoesz et al., 2007), and between music training and memory for verbal and visual stimuli (Jakobson et al., 2008). Closer inspection of their methods, consideration of the available literature, and a reanalysis of previous data reveal that these conclusions are debatable. Moreover, the causal direction of the observed associations could go either or both ways.
Article
Objective Cognitive dysfunction and neuropsychiatric disturbance are common in systemic lupus erythematosus (SLE). This study addressed the ability of the Automated Neuropsychological Assessment Metrics (ANAM), a computerized cognitive testing battery consisting of cognitive subtests, a sleepiness rating scale, and a mood scale, to predict neuropsychological status in patients with SLE.Methods Sixty individuals with SLE and no overt neuropsychiatric symptoms were administered ANAM to determine its validity as a screening measure of cognitive dysfunction and emotional distress in SLE.ResultsPerformance on ANAM was compared with results of a consecutively administered, 2-hour battery of traditional neuropsychological tests and the Beck Depression Inventory II (BDI-II). Individual ANAM cognitive test scores were significantly correlated with most neuropsychological tests, particularly those measuring psychomotor processing speed and executive functioning. Using logistic regression, ANAM cognitive subtests successfully predicted individuals with SLE who had probable versus no impairment after controlling for premorbid levels of cognitive ability. Sensitivity of group classification was 76.2% and specificity was 82.8%, with 80% correct classification overall. ANAM's ability to predict neuropsychological functioning remained even after controlling for subjective reports of depressed mood and current sleepiness. Further, the ANAM mood scale was significantly correlated with the BDI-II (r = 0.67, P < 0.001), indicating its potential future use as a screening tool for emotional distress.ConclusionANAM shows promise as a time- and cost-efficient tool for screening and monitoring cognitive and emotional functioning in SLE, and can indicate when a more thorough neuropsychological investigation is warranted.
Chapter
Clinical neuropsychologists are professionals within the field of psychology with special expertise in applying the principles of brain-behavior relationships to individuals with various neurological injuries or illnesses, as well as other medical, developmental, and/or psychiatric conditions (National Academy of Neuropsychology [NAN], 2001). Using various tests, techniques, and principles, neuropsychologists evaluate individuals’ cognitive, behavioral, and emotional strengths and weaknesses, and the impact of these on the person’s ability to function. This information, combined with information from other professionals (physician, occupational, speech-language, physical therapists, etc.) and families/significant others, is utilized to develop, recommend, and implement treatment interventions.
Article
Several reports show that traumatic brain injury (TBI) results in abnormalities in the coordinated activation among brain regions. Because most previous studies examined moderate/severe TBI, the extensiveness of functional connectivity abnormalities and their relationship to postconcussive complaints or white matter microstructural damage are unclear in mild TBI. This study characterized widespread injury effects on multiple integrated neural networks typically observed during a task-unconstrained "resting state" in mild TBI patients. Whole brain functional connectivity for twelve separate networks was identified using independent component analysis (ICA) of fMRI data collected from thirty mild TBI patients mostly free of macroscopic intracerebral injury and thirty demographically-matched healthy control participants. Voxelwise group comparisons found abnormal mild TBI functional connectivity in every brain network identified by ICA, including visual processing, motor, limbic, and numerous circuits believed to underlie executive cognition. Abnormalities not only included functional connectivity deficits, but also enhancements possibly reflecting compensatory neural processes. Postconcussive symptom severity was linked to abnormal regional connectivity within nearly every brain network identified, particularly anterior cingulate. A recently developed multivariate technique that identifies links between whole brain profiles of functional and anatomical connectivity identified several novel mild TBI abnormalities, and represents a potentially important new tool in the study of the complex neurobiological sequelae of TBI.
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Data from the WAIS-R standardization sample was used to generate a premorbid IQ estimation formula using both demographic and current performance variables. The sample was randomly divided into two groups for development and cross-validation of the formula. Age, education, occupation, race, Vocabulary subtest raw score, and Picture Completion subtest raw score were used as predictor variables. The formulas for Verbal, Performance, and Full Scale IQ were highly significant and accurate in prediction, without the substantial restriction of range or overestimation found in other methods. Formulas for use with a lateralized population are also presented.
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Investigated the efficacy of the variables age, sex, race, education, occupation, rural–urban residence, geographic residence, and handedness in predicting premorbid IQ on the WAIS—R. Data were from the 1981 WAIS—R standardization sample. Results indicate that education, race, and occupation were the most powerful predictors of premorbid IQ and that the present estimation formulas can assist in predicting premorbid IQ on the WAIS—R. (6 ref) (PsycINFO Database Record (c) 2012 APA, all rights reserved)
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Assessed 45 patients with a probable diagnosis of dementia of the Alzheimer type (DAT), varying from minimal to moderate levels of dementia, on 3 tasks of reading aloud: (1) an extensive list of regular and exception words across a range of word frequencies, (2) the National Adult Reading Test (NART), and (3) a test of nonword reading. On the first test, the patients showed substantial effects of regularity, word frequency, and disease severity. Reading of less common words with atypical spelling-sound correspondences was significantly impaired in the moderately demented subgroup of patients and significantly correlated with measures of semantic memory for the patient group as a whole. This impaired exception word reading was attributed to the breakdown in semantic memory that occurs as the DAT disease process advances. A significant drop in performance on both the NART and nonword reading also accompanied increasing disease severity. (PsycINFO Database Record (c) 2012 APA, all rights reserved)
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Correlated the assessment of brain damage vs. no brain damage and of right vs. left brain damage with factors and individual subtest results obtained from a factor analysis of the WAIS. Corresponding groups of 103 hospitalized patients were used. Results demonstrate that the WAIS was affected by brain damage although its factor structure was not. The general scores in each factor were reduced while the structure of the general, verbal, performance, and memory factors was not greatly changed from normal WAIS factors. All subtests, especially Digit Symbol, were affected but not in accordance with Wechsler's Deterioration Index. Laterality of brain damage was not related to verbal and performance factors in chronic brain damage although the Digit Span was significantly more impaired by left-hemisphere damage. (26 ref.)
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A study by Wiens, Bryan, and Crossen (1993) suggests the Wide Range Achievement Test-Revised (WRAT-R) Reading subtest and North American Adult Reading Test (NAART) are adequate predictors of Wechsler Adult Intelligence Scale-Revised (WAIS-R) IQ scores for a normal population. Although it is common practice to use reading scores to estimate premorbid IQ in clinical populations, the WRAT-R and NAART have not been compared using individuals with brain dysfunction. The current study cross-validated the Wiens et al. (1993) study using neurologically impaired populations: traumatic brain injury (n = 118), dementia (n = 37), and other neurologic impairments (n = 77). The results were generally consistent across all three groups: (a) the WRAT-R and NAART were equivalent and accurate estimates of average VIQ levels; (b) the WRAT-R and NAART were equivalent but underestimates of higher intelligence ranges; and (c) the WRAT-R is a more accurate estimate for lower VIQ ranges, although both are overestimates. This third finding is in contrast to Wiens et al.'s (1993) results that suggest the WRAT-R is an accurate estinate of lower IQ ranges for normals. It is concluded that the WRAT-R is the preferred measure of premorbid verbal intelligence for psychometric and clinical reasons.
Article
The authors assessed 45 patients with a probable diagnosis of dementia of the Alzheimer type (DAT), varying from minimal to moderate levels of dementia, on 3 tasks of reading aloud: (a) an extensive list of regular and exception words across a range of word frequencies, (b) the National Adult Reading Test (NART), and (c) a test of nonword reading. On the first test, the patients showed substantial effects of regularity, word frequency, and disease severity. Reading of less common words with atypical spelling-sound correspondences was significantly impaired in the moderately demented subgroup of patients and significantly correlated with measures of semantic memory for the patient group as a whole. This impaired exception word reading was attributed to the breakdown in semantic memory that occurs as the DAT disease process advances. A significant drop in performance on both the NART and nonword reading also accompanied increasing disease severity.
Article
In a preliminary effort to improve the early diagnosis of dementia, we developed a regression-based method for estimating premorbid intelligence measured by the ability to read irregular words from the American version of the Nelson Adult Reading Test (AMNART). Using errors on the AMNART and years of education, a model for predicting current verbal intelligence (VIQ) was developed in a sample of nondemented elderly. Double cross validation showed that the model had high accuracy and stability in estimating current VIQ in nondemented subjects. The model was then used to estimate premorbid VIQ in mildly demented subjects. Estimated premorbid IQ exceeded current IQ by at least 10 points and did not differ from that of nondemented subjects. Less than 10% of nondemented elderly had discrepancies that were as large. If intellectual decline predicts future functional loss and can be reliably measured using cross-sectional data, the requirement of functional impairment may be an unnecessary barrier to the early diagnosis of dementia.
Article
Examined the accuracy of the North American revision of the National Adult Reading Test (NART-R; Blair & Spreen, 1989) in predicting current WAIS-R FSIQ scores in a sample of 302 healthy job applicants. Also wished to establish adult norms for the NART-R according to age, education, and level of intelligence. Finally, also compared the accuracy of the NART-R in predicting WAIS-R FSIQ scores with that of the Reading Subtest of the Wide Range Achievement Test-Revised. Using the prediction equations developed by Blair and Spreen, estimated and obtained mean WAIS-R FSIQs were found to be nearly identical for the group as a whole, with r = .46 (p < 001). However, WAIS-R FSIQ was overestimated by NART-R performance among lower IQ groups, and underestimated among higher IQ groups. The WRAT-R Reading Score correlation with WAIS-R FSIQ was r = .45 (p < .001); the Reading Score also underestimated among higher IQ groups. Using the NART-R, 95% of the subjects had less than 15-point estimated-obtained IQ differences, supporting this cutoff as a potentially useful indicator of deterioration.
Article
A sample of 200 healthy individuals, representative of the adult UK population in terms of age, gender, and occupational classification, completed a full-length WAIS-R. Demographic variables for the participants were recorded (age, gender, years of education, and occupational classification) and used to develop regression equations for the estimation of premorbid WAIS-R IQ. Stepwise multiple regression revealed that occupation was the best predictor of IQ for all three WAIS-R scales (FSIQ, VIQ, and PIQ). Age and years of education significantly increased the variance predicted. Together these three variables accounted for 53%, 53%, and 32% of the variance in FSIQ, VIQ, and PIQ, respectively. The results indicated that the demographic approach to the estimation of premorbid WAIS-R IQ has utility beyond the USA. However, in common with findings for American participants (Barona, Reynolds, & Chastain, 1984) the ability to predict PIQ was markedly inferior to that achieved for FSIQ and VIQ. A frequency table of the discrepancies between estimated premorbid IQ and obtained IQ for the present sample is provided for clinical use.
Article
The present research is an effort to evaluate a new method of estimating premorbid IQ in which both demographic and current performance methods are utilized in a regression algorithm. Two hundred and twenty-seven patient files from the archives of the University of Oklahoma Health Sciences Center were used to evaluate the Oklahoma Premorbid Intelligence Estimation (OPIE) procedure. This procedure combines both premorbid demographic variables of age, education, occupation, and race with current performance on the WAIS-R Vocabulary and Picture Completion subtests in estimating premorbid IQ. The results are presented for clinical populations including those with dementia, traumatic brain injury, cerebral vascular accident, neoplasm, epilepsy, and a medical control chronic pain group. Results indicate that the OPIE produces a less restricted range of scores than other currently available methods of estimating premorbid IQ without systematic under or over-estimation of IQ. Considerations for the use of this method with diffuse and cerebrally lateralized populations are discussed.
Article
The National Adult Reading Test (NART) has promise as an assessment tool for the determination of premorbid intellectual function, but needs to be modified for current use in a North American population and validated against the WAIS-R. A revision based on American and Canadian pronunciation rules was prepared. Sixty-six unimpaired subjects were tested with a revised NART and all subtests of the WAIS-R. Demographic variables were also recorded. Correlations between actual VIQ, PIQ and FSIQ, and predicted IQs on the basis of revised NART score were .83, .40, and .75, respectively (all p < .001). Prediction of IQs was more accurate with equations based on revised NART score than with demographic variable prediction equations developed by Barona, Reynolds, and Chastain (1984).
Article
Reviews the work over a 5-yr (1981–1985) period that has been conducted subsequent to the summary on measures of cognitive, intellectual, and neuropsychological premorbid functioning levels by R. C. Klesges et al (see record 1982-04747-001). Several additional articles are reviewed, new regression formulas are outlined, and an attempt is made to meld a diverse and controversial literature. New data are presented to provide cross-validational support of a recent formula, and future possible research directions are explored. (PsycINFO Database Record (c) 2012 APA, all rights reserved)
Article
Judgment of neuropsychological decline is typically made by comparing a patient's current cognitive performance to data from demographically similar normal individuals. Even within narrowly defined demographic categories, however, there is variability in level of performance, approximating the normal curve. The present study explored the degree to which oral reading scores on the American National Adult Reading Test (ANART) could more accurately predict a person's test performance relative to other demographically similar individuals. In a sample of 141 neurologically healthy participants, the ANART added modestly to the precision of WAIS–R Verbal and Full Scale IQ and Learning score predictions, beyond that achieved by demographics alone; however, ANART score did not significantly improve estimation of Performance IQ, Average Impairment Rating, or Memory score. Use of the ANART tended to improve demographic predictions primarily with “outlier” participants whose oral reading skills were relatively poor. For Verbal IQ, ANART helped with participants who had both poor ANART and relatively high education. Oral reading can be useful for estimating premorbid verbal intelligence and learning in combination with demographic variables, but it does not appear to improve estimates of other neurocognitive abilities. (JINS, 1999, 5, 247–254.)
Article
It is frequently necessary in research and clinical evaluations to obtain estimates of premorbid intelligence (IQ) which are separate from measured IQ. There is evidence that word reading may be useful in this aim. In order to determine the potential of the Wide Range Achievement Test-Revised (WRAT-R) reading subtest (READ) as an estimate of premorbid IQ, the present study examined the relationship between READ and IQ in healthy subjects. Consistent with other findings, READ accounted for a significant amount of variance in Verbal, Performance, and Full Scale IQ. Race and parental education, the latter being a variable not previously examined in this literature, accounted for incrementally valid variance in IQ beyond READ. The predictive power of these variables compares favorably with estimates made by the Barona IQ estimation formula, which uses only demographic information.
Article
Compendio de pruebas neuropsicológicas en que se ofrece también la información necesaria para seleccionar el test adecuado, cómo aplicarlo, cómo preparar al cliente, cómo interpretar los resultados y cómo ponerlos por escrito, así como duración, costo y validación de cada uno de ellos.
Article
The NART is a new word-reading test which was specifically designed for use with adults: the 50 words were selected in order to assess familiarity with words rather than the ability to phonetically decode unfamilar words, i.e. for each word intelligent guesswork alone would not result in a correct response. The results from a group of patients with cortical atrophy and a control group demonstrated the superiority of the NART over the best previously available word list (the Schonell GWRT) in enabling higher and more accurate levels of intelligence to be predicted. The evidence implied that the reading of the NART words was not significantly affected by the dementing processes in the patients with cortical atrophy, and therefore that the NART reading score can provide an accurate estimate of premorbid intelligence levels in these patients.
Article
Barona, Reynolds, and Chastain (1984) proposed new demographic information formulas for estimating premorbid Wechsler Adult Intelligence Scales-Revised IQ-scores. Our study was directed toward the following issues: (a) cross-validation of this index on a neurologically normal but clinically relevant criterion group, and (b) determining the neuropsychological utility of the formulas to discriminate between neurologically normal and brain-impaired populations. Our subjects included 80 neurologically normal patients and 83 brain-impaired patients. Cross-validation results generally support the estimation accuracy of the formulas within a neurologically normal clinical sample, although by all three formulas, scores are significantly overestimated. To determine the neuropsychological usefulness of the formulas, we derived a difference score (D-score) cut-point method. D-score diagnostic discrimination of patients was slightly greater than obtained IQs, but not at a statistically significant level. Suggestions for clinical use and further research with the Barona Index are provided. (10 ref) (PsycINFO Database Record (c) 2012 APA, all rights reserved)
Article
Reading tests are assumed to be accurate estimates of premorbid intelligence, based on the belief that reading remains relatively stable following cerebral injury/disease. However, this assumption has been primarily inferred only from studies comparing differences in reading/intelligence measures between neurologically impaired and normal groups. The current study, using within-subject comparisons, compared the longitudinal stability of reading (WRAT-R/3) and intelligence (WAIS-R FIQ) scores for 39 individuals with cognitive dysfunction referred for repeat neuropsychological evaluation. Wilcoxon signed-ranks tests indicated that reading scores: (1) did not statistically change for those demonstrating intellectual decline (> 0 point decline in FIQ), or for those who remained relatively stable (FIQ increase between 0 and 6 points) over retest, but (2) did significantly improve for those demonstrating intellectual improvement greater than 6 points. These results suggest that reading scores may be appropriately considered as "hold" tests for individuals who intellectually decline/remain stable over time, but not for those demonstrating significant intellectual improvement. Additionally, significant variability in reading score decline/improvement suggests that caution must be used when estimating premorbid intelligence based on WRAT-R/3 Reading scores.
Article
The estimation of premorbid ability levels has been debated for some time. Some of the difficult issues involved are reviewed here and comments provided on certain approaches, some of which tend to be popular for reasons of convenience and false beliefs of their accuracy, and some that are less well-known. Demographic estimation procedures in particular tend to fare better than believed in some research. An additional approach is recommended for further research, one that is equally applicable to children and adults, and that takes maximum advantage of the known relationships among IQ and genetic and environmental variance in intellectual development. © 1997 National Academy of Neuropsychology. Published by Elsevier Science Ltd
Article
Clinical neuropsychological assessment frequently requires the comparison of obtained scores against some estimate of premorbid level of functioning, but only recently has significant attention been turned to objective methods to accomplish this objective. Clinical judgment, although useful in some circumstances, is generally insufficient. Other methods of estimating premorbid function include demographic regression formulae, such as the Barona formula, subtest scatter methods, such as that suggested by Lezak, and the use of current scores on tests of presumably spared abilities, such as the National Adult Reading Test (NART). Almost all methods predict to some general level of intellectual functioning rather than to specific neuropsychological skills. This paper reviews the suggested methods in terms of the underlying assumptions and the available empirical evidence. Suggestions for future research include the development of skill specific predictors as well as investigations regarding the relation between predictor accuracy and characteristics of the subject, such as high versus low premorbid functioning in the subject. Additionally, there is a great need for methods to predict premorbid functioning in children. © 1997 National Academy of Neuropsychology. Published by Elsevier Science Ltd
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