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Managing logistics risks in pharmaceutical supply chain: a 4PL perspective

Taylor & Francis
Production Planning & Control
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As of March11, 2020 the world Health Organization (WHO) declared Corona virus disease 2019 (COVID-19) as a pandemic. The disastrous outbreak of Covid-19 is described as humanity’s worst crisis since World War II. Effectively, not only has it caused severe disruptions around the world at different levels–social, economic, political-but it has also acutely disrupted supply chains worldwide. Pharmaceutical supply chain is a significant component of the health system as to supplying medicines. Today, pharmaceutical companies face a tremendous array of risks. The purpose of this research is to assess different risks in Tunisian pharmaceutical supply chain during this challenging period due to COVID-19 pandemic by providing quantified empirical results. Based on the review of literature, some major risks affecting the pharmaceutical supply chain are identified as regulatory risk, inventory risk, counterfeit risk and financial risk. The fuzzy AHP method is used, in this work, in order to identify the most important risk. It has to be noted that the top risk identified in pharmaceutical supply chain is that related to the Supply and suppliers.
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Network design plays an essential role in logistics supply chain management. Under fourth-party logistics (4PL), an industry innovator mode helps to balance the service satisfaction of both suppliers and customers. In this study, this “balancing” advantage is investigated, and a novel network is proposed for 4PL platforms. Specifically, a mixed-integer nonlinear programming model is developed to maximize the service satisfaction of both sides under a limited budget, and to determine the locations for transshipment centers (TCs), third-party logistics (3PL) providers between parties, and transport volumes. The service satisfaction is defined according to prospect theory. Considering the NP-hard characteristic of the problem and its complicated objective function, a particle swarm optimization plus (PSO+) algorithm integrating an average adjustment (AA) strategy is introduced for managing complex budget constraints. A series of numerical experiments are conducted to validate the effectiveness and efficiency of the model and algorithm. The results provide strong evidence for certifying the performance of the model, in which both suppliers and customers can achieve their anticipated service levels.
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Purpose This study develops and tests a model exploring the relationship between supply chain (SC) counterfeit risk management and performance in the healthcare supply chain (HCSC). Design/methodology/approach In the proposed theoretical model, HCSC counterfeit risk management is characterized by HCSC counterfeit risk orientation (HCRO), HCSC counterfeit risk mitigation (HCRM) and HCSC risk management integration (HRMI), while performance is represented by healthcare logistics performance (HLP) and healthcare organization overall performance (HOP). Partial least squares structural equation modeling (PLS-SEM) and survey data from 55 HCSC managers are used to test the research hypotheses. Findings HCRO has a significant positive effect on HCRM, while HCRM has a positive impact on HRMI. With respect to HLP, HCRM has a nonsignificant effect, while HRMI has a significant impact, thus confirming the important mediating role of HRMI. Finally, HLP has a significant positive effect on the overall performance of healthcare organizations. Research limitations/implications All study participants were from the United States, limiting the generalizability of the study findings to different countries or regions. The sample size employed in the study did not allow the authors to distinguish among the different types of healthcare organizations. Originality/value This study delineates between a healthcare organization's philosophy toward counterfeiting risks vs actions taken to eliminate or reduce the impact of counterfeiting on the HCSC. By offering firm-level guidance for managers, this study informs healthcare organizations about addressing the challenge of counterfeiting in the HCSC.
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The United States government has identified the health care sector as part of the critical infrastructure for homeland security to protect citizens against health risks arising from terrorism, natural disasters, and epidemics. Citizens also have expectations about the role that health care plays in enjoying a good quality of life, by providing response systems to handle emergencies and other illness situations adequately. Among the systems required to support desired performance levels is a robust and resilient pharmaceutical supply chain that is free of disruption. Shortages of drugs place undue pressure on healthcare providers to devise alternative approaches to administer patient care. With climate change expected to result in increasingly severe weather patterns in the future, it is critical that logistics engineers understand the impact that a catastrophic weather event could have on supply chain disruption to facilitate the design of supply systems that are robust and resilient. This study investigates the main causal and intermediate events that led to risk propagation in, and disruption of, the U.S. pharmaceutical supply chain following Hurricane Maria. A causality Bayesian model is developed to depict linkages between risk events and quantify the associated cumulative risk. The quantification is further examined through different advanced techniques such as predictive inference reasoning and sensitivity analysis. The general interpretation of these analyses suggests that port resilience is imperative to pharmaceutical supply chain performance in the case of Puerto Rico.
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Service supply chain management is more and more complex and managers find that old-style methods fall short in effectively addressing many associated challenges. Although risk management in supply chains is continuing to obtain momentous attention in the extant literature, investigation on risk aspects connecting to tactical sourcing crossways various industry segments from a transnational viewpoint is scant. The objective of this study is to investigate the effect of social ties, institutional support and inter-agency collaboration in mitigating service supply chain risk in the healthcare sectors. Qualitative and quantitative approaches were used to collect data from 171 respondents from Ethiopia. Partial least square structural equation model is applied to examine the association among these latent variables and the dependent variable. The result of the study indicates inter-agency collaboration plays a critical role in managing service supply chain risk, especially in volatility, uncertainty, complexity, and ambiguity environment. As for practical contributions, results may be helpful to policymakers, managers and organizations to do their jobs better or build competitive advantage by responding the issues and problems related to healthcare individual managers, organizations, and their partners.
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Trucking industry plays a major role in the transportation of goods across different geographical locations. The operational complexities of the trucking industry lead to various risks. This study focuses on effective design and implementation of risk-mitigation strategies for the trucking industry with consideration for budget restrictions. In this paper, both subjective and objective attributes are considered in the mathematical modeling and thereby tries to capture realism in the strategic decision-making process. The results of the study provide novel insights that relate the impact of risk on the cost of mitigation. Further, the effect of three characteristics, targeted risk level (TRL), implementation cost (IC) of strategy, and the probability of risk occurrence (PO) is shown in designing and developing risk-mitigation strategies. The experimental analysis not only augments theoretical knowledge related to risk management decision-making processes but also contributes to designing and developing a risk-mitigation strategy under economic constraints. From the managerial perspective, the study demonstrates how decision-makers can benefit from an integrated approach to develop a more holistic understanding of risk-management processes. This study also provides guidelines in policy selection considering higher return on investment (ROI). The paper concludes by highlighting the key findings and discussing opportunities for future research.
Article
Purpose Risk management is crucial for all organizations, especially those in the global supply chain network. Failure may result in huge economic loses and damage to company reputation. Risk assessment usually involves quantitative and qualitative decisions. The purpose of this paper is to apply fuzzy logic to capture and inference qualitative decisions made in the House of Risk (HOR) assessment method. Design/methodology/approach In the existing HOR model, aggregate risk potential (ARP) is calculated by the risk event times the risk agent value and its occurrence. However, these values are usually obtained from interviews, which may involve subjective decisions. To overcome this shortcoming, a fuzzy-based approach is proposed to calculate ARP instead of the current deterministic approach. Findings Risk analyses are conducted in five major categories of risk sources: internal, global environment, supplier, customer and third-party logistics provider. Moreover, each category is further divided into different sub-categories. The results indicate that the fuzzy-based HOR successfully inferences the inputs of the risk event, risk agents and its occurrence, and can prioritize the risk agents in order to take proactive decisions. Practical implications The proposed fuzzy-based HOR model can be used practically by manufacturers in the global supply chain. It provides a framework for decision makers to systematically analyze the potential risks in different categories. Originality/value The proposed fuzzy-based HOR approach improves the traditional approach by more precise modeling of the qualitative decision-making process. It contributes to a more accurate reflection of the real situation that manufacturers are facing.
Article
Supply chain risks are one of the significant hurdles faced by the organisations in achieving operational excellence. The purpose of this study is to assess the supply chain risks in the pharmaceutical industries and their influence on supply chain operational performance (SCOP). Through extent literature review, we have identified 44 items which are classified under five constructs consisting of supplier risk (SR), production risk (PR), demand risk (DR), infrastructure risk (IR) and macro risk (MR). Using these constructs, a structured questionnaire has been developed. An online survey was conducted in the pharmaceutical industries yielding a response rate of 66.20%. To validate the hypotheses between these constructs and SCOP, we used Structural equation modelling (SEM). From the SEM result expect demand risks, all other threats have the negative relationship with SCOP (i.e., the higher the chances, the lower the SCOP).Further, to rank the organisation based on their SCOP, we proposed a supply chain risk assessment index (SCRAI) based on the ratings obtained from the experts using Fuzzy techniques. From these results, it is clear that SCRAI is essential for evaluating the organisation's efficiency on supply chain operations. Keywords: supply chain risks; pharmaceutical industries; supply chain operational performance; SCOP; risk index. 2 V. Raja Sreedharan et al. Reference to this paper should be made as follows: Raja Sreedharan, V., Kamala, V. and Arunprasad, P. (xxxx) 'Supply chain risk assessment in pharmaceutical industries: an empirical approach', Int.
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With the expansion of the medical assistance scheme in 2012, the consumption of pharmaceutical products in the Moroccan public sector increased exponentially. Several assessments of the current supply chain of pharmaceutical products indicated the saturation of the logistical system and its inadequacy to the new challenges faced. The purpose of this paper is to elaborate a general approach to distribution network redesign. Based on prioritized criteria, such as supply chain responsiveness and costs, it allows comparing different distribution network designs and selecting the most appropriate one using AHP multi-criteria decision making method. This general approach is applied to the case study of the Moroccan pharmaceutical supply chain in the public sector.
Article
Purpose The purpose of this paper is to review the extant literature on supply chain risk management (SCRM, including risk identification, assessment, treatment, and monitoring), developing a comprehensive definition and conceptual framework; to evaluate prior theory use; and to identify future research directions. Design/methodology/approach A systematic literature review of 354 articles (published 2000-2016) based on descriptive, thematic, and content analysis. Findings There has been a considerable focus on identifying risk types and proposing risk mitigation strategies. Research has emphasised organisational responses to supply chain risks and made only limited use of theory. Ten key future research directions are identified. Research limitations/implications A broad, contemporary understanding of SCRM is provided; and a new, comprehensive definition is presented covering the process, pathway, and objectives of SCRM, leading to a conceptual framework. The research agenda guides future work towards maturation of the discipline. Practical implications Managers are encouraged to adopt a holistic approach to SCRM. Guidance is provided on how to select appropriate risk treatment actions according to the probability and impact of a risk. Originality/value The first review to consider theory use in SCRM research and to use four SCRM stages to structure the review.
Article
Purpose The purpose of this paper is to present a methodology to analyze the risks present in perishable food supply chain and to determine the most effective risk mitigation strategies. It is achieved by understanding the dynamics between various risks in perishable food supply chain and modeling them using interpretive structural modeling (ISM). Design/methodology/approach Four categories and 17 types of risk are established from literature and conducting brainstorming sessions with managers/engineers in Indian dairy firms. A methodology is proposed using ISM, risk priority number and risk mitigation number to prioritize risk mitigation strategy decisions for the dairy industry. Findings For a perishable food supply chain, risk positioned at lower levels (levels 1 or 2) in the hierarchy should be targeted first, while formulating mitigation strategies. To investigate further, risk- enabling factors which are identified for an Indian dairy firm for these levels 1 and 2 risks and mitigation strategy prioritization show that supplier side risks are more dominant followed by market risks and process risks. Research limitations/implications This proposed methodology has not been statistically validated or empirically tested, and factors taken are in the Indian context, but the authors believe that the study is highly relevant to other markets as well because the ISM-based analysis is for generic perishable food supply chain environment. Practical implications This study provides a useful approach to managers/decision makers to identify, analyze and prioritize risk in the supply chain. It also provides insights into the mutual relationships of supply chain risks which would help them to focus on the effective risk mitigation strategies formulation. The study provides the insights to benchmark and risk management in the dairy industry environment with priority considerations. Originality/value This paper provides an integrated approach to identifying, quantify, analyze, evaluate and mitigate the risks of perishable food (in the dairy environment) in the Indian context.
Article
The purpose of this paper is to determine the main security threats in supply chains, to understand gaps in today’s supply chain management strategies and to make recommendations to enhance security in the context of supply chain management. Previous research lacks comprehensive studies and recommendations about how supply chain managers deal with security issues in line with the business visions and strategies of their companies. The study methodology is based on an exploratory approach. Data were collected from 20 managers from international companies by means of self-administered surveys, one-to-one interviews and group interviews. Study findings point out risk management as an important tool at the disposal of managers for trading off performance and vulnerability. However, some important challenges also need to be considered, such as lack of data, insiders, IT vulnerabilities, regulatory frameworks, criminal behaviour, etc. Hence, recommendations are made for managers to improve their understanding of supply chain security.
Article
Purpose – From a synthesis of literature, the purpose of this paper is to present a conceptual risk management framework, showing the effect of logistics outsourcing on the supply chain vulnerability (SCV) of shippers. The framework is designed to assist practitioners and academics in better understanding the key research, management as well as operational aspects involved. Design/methodology/approach – A literature review is conducted and based on these findings a conceptual framework developed. Findings – Logistics outsourcing is increasingly used by shippers, but the specific aspect of supply chain risk management (SCRM) and SCV in this context is rarely covered in research and implementation in practice is limited. Logistics outsourcing can have an ambiguous effect on the SCV of shippers and is influenced by other internal and external factors. Research limitations/implications – Literature directly dealing with logistics outsourcing and SCV/SCRM is rare and thus the framework is built on insights, compiled from the distinct research areas. Further research should be performed on this nascent topic. Practical implications – Shippers may use the framework to revise their risk management strategy and actively use logistics outsourcing to decrease SCV. Logistics service providers can tailor their services specifically toward clients and thus both can be better prepared for future supply chain disruptions. Originality/value – This paper looks specifically at SCV and SRCM of shippers with regards to logistics outsourcing.
Article
This paper analyses the interrelationships between risks faced by third party logistics service providers (3PLs) in relation to one of its customers using DEMATEL. Novel analysis of both within and between risk categories and generation of threshold value to prioritize risks generate useful insights. Results show that arms-length relationship between the customer and the 3PLs has strong influence on other risks and there is a need for collaborative relationships between 3PLs and its customers. Moreover, analysis indicates that the 3PLs need to improve internal processes related to quality management, flexibility of its operations and also geographical coverage of their services.