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404 Innovation in Aging, 2023, Vol. 7, No. S1
Aquitaine, France, 3. Norwegian University of Science and
Technology, Trondheim, Nord-Trondelag, Norway
After a hip fracture, rehabilitation starts with the primary
aim to get older persons back on their feet and mobile again.
Multidisciplinary hospital treatment is suggested as the rst
essential step for optimization of care immediately after the
fracture, followed by subacute exercise interventions to fur-
ther improve mobility. However, reported outcomes of re-
habilitation vary widely geographically and within regions
and most often consist of repeated physical capacity meas-
ures without knowledge of the actual mobility behaviour
of patients after hospital care. Evidence emerges that small
changes in physical capacity (e.g., gait speed) coincide with
larger changes in physical activity (e.g., number of steps)
during the rst six months post-fracture. In a pooled longitu-
dinal analysis of n=785 hip fracture patients (mean age: 83.4
years, SD=6.1) from Germany and Norway, we found daily
walking duration trajectories to increase until week 28 post
surgery, and that 50% of the peak mobility was achieved
within the rst four weeks. Still, in order to better under-
stand the underlying mechanisms of mobility performance
and to improve rehabilitation measures, in-depth data on pa-
tients’ real-world mobility beyond walking volume is needed.
Therefore, in the Mobilise-D project, a novel sensor algo-
rithm is used to quantify patients’ real-world mobility with
higher granularity and more extensive information. Baseline
data on physical capacity measures, sensor-based mobility
outcomes, and patient-reported outcomes of mobility and
function of n= 454 (mean age: 78.1 years, SD=9.2) hip frac-
ture patients is presented.
Abstract citation ID: igad104.1335
LISTENING TO THE PATIENTS' VOICE: A
CONCEPTUAL FRAMEWORK OF HIP FRACTURE
PATIENTS' WALKING EXPERIENCE
LauraDelgado-Ortiz1, AshleyPolhemus2, AlisonKeogh3,
LynnRochester4, AnjaFrei2, MiloPuhan2, and
JudithGarcia-Aymerich5, 1. ISGlobal, Barcelona, Catalonia,
Spain, 2. Zürich University, Zürich, Zurich, Switzerland,
3. University College Dublin, Dublin, Dublin, Ireland,
4. Newcastle University, Newcastle upon Tyne, England,
United Kingdom, 5. IS Global, Barcelona, Catalonia, Spain
Walking is crucial for an active and healthy ageing, but
it changes with age and in the presence of diverse health
conditions, including hip fracture and frailty. So far, con-
ceptual frameworks of walking have not included the im-
pact of these conditions and individuals’ lived experiences
on their walking. Thus, we aimed to identify and synthesize
evidence describing the walking experience from the perspec-
tive of individuals recovering from a hip fracture, as well as
from the perspective of individuals living with highly preva-
lent walking-impairing conditions of diverse etiology. We
conducted a systematic review and meta-ethnography, fol-
lowing appropriate guidance. Out of 2,552 unique records,
117 (8.5% hip fracture) were deemed eligible for the meta-
ethnography. We identied seven themes that explain the
experience of walking: (1) becoming aware of the walking
experience, (2) the walking experience as a link between in-
dividuals’ activities and sense of self, (3) the physical walking
experience, (4) the mental and emotional walking experi-
ence, (5) the social walking experience, (6) the context of
the walking experience, and (7) behavioral and attitudinal
adaptations resulting from the walking experience. We pro-
posed a framework that describes the interplay between
these themes, providing a conceptualization of walking that
is grounded in the experiences of individuals recovering
from a hip fracture or living with other walking-impairing
health conditions, and that may be used to set priorities and
improve patient centricity in clinical practice, research and
public health initiatives.
SESSION 3555 (SYMPOSIUM)
Abstract citation ID: igad104.1336
GETTING BETTER OR GETTING WORSE: MARKERS
OF LONGEVITY ACROSS COHORTS AND
COUNTRIES
Chair: PeterMartin Co-Chair: YasuyukiGondo Discussant:
OscarRibeiro
The expansion of life expectancy and the lengthening
of the human life span are extraordinary achievements ob-
served over the last century. Among those accomplishments
is the increasing number of centenarians in many countries.
However, it is not clear whether new cohorts of centenarians
are in better health when compared to earlier born cohorts of
centenarians. The purpose of this symposium is to compare
centenarian cohorts across different countries. Two centen-
arian cohorts each from Hong Kong, Japan, and the United
States are included in the analyses. Results provide different
perspectives across countries. The Hong Kong Centenarian
Studies compared current centenarians to those who partici-
pated at an earlier time and noted that proxies in the second
study rated centenarians in worse health when compared to
centenarian self-ratings. The Kyotango study assessed living
conditions, care need level, ADL, IADL, and cognitive func-
tion by gender and noted cognitive improvement for men.
Finally, later cohorts of the U.S. Health and Retirement Study
were in worse health when compared to the earlier born co-
hort. The results provide an indication for policy makers and
practitioners who will prepare for a larger number of cen-
tenarians in need of additional support. Although some im-
provement for later born cohorts is noticeable, it is obvious
that more care provision will also be needed as centenarians
around the world will survive with more health conditions.
Additional research should evaluate centenarians in other
parts of the world.
Abstract citation ID: igad104.1337
INTRODUCING CENTENARIAN STUDIES IN AN
AGING WORLD
PeterMartin, Iowa State University, Ames, Iowa, United Sta
tes
Centenarian studies have come of age. With the rst com-
prehensive centenarian studies conducted more than 35 years
ago, there are now centenarian databases in the United States,
in Europe, and in Asian countries. The major focus of these
studies has been on genetic and family longevity factors, on
support systems, personality, and on health behaviors. Another
emphasis has been on various health components, such as
physical health, mental health, frailty, and psychological
well-being. In recent years, a second generation of centenarian
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Innovation in Aging, 2023, Vol. 7, No. S1 405
studies has been initiated, comparing earlier born cohorts with
later born cohorts. Among the rst studies conducting a co-
hort comparison, the Danish centenarian studies, the Georgia
centenarian studies, and the Tokyo centenarian studies showed
inconsistent results. Whereas some studies indicated that
later born cohorts enjoyed higher levels of functioning (e.g.,
Denmark, U.S. Georgia), other studies showed poorer perform-
ance (e.g., Japan). The current symposium sheds additional
light on cohort comparisons with recently collected data from
the second Hong Kong Centenarian Study, the Kyotango cen-
tenarian cohort, and the Health and Retirement Study. This
presentation summarizes major ndings from centenarian
studies conducted around the world and highlights activities
of the International Consortium of Centenarian Studies (ICC).
Abstract citation ID: igad104.1338
IMPROVING COGNITIVE FUNCTION IN THE NEW
COHORT—BUT ONLY FOR MEN. FINDINGS FROM
THE KYOTANGO CENTENARIAN STUDY
YasuyukiGondo, and XinyuZhang, Osaka University,
Suita, Osaka, Japan
The Kyotango Centenarian Cohort Study was established
with the aim of tracing long-term changes in the overall
functioning of centenarians. This study started in 2014 in
Kyotango City. Since then, new centenarians and those who
were expected to be 100 years old the following April were
invited to the study every year in September. Eligible centen-
arians were invited by the city, and centenarians and their
families agreed to participate to answer questions either by
mail or face-to-face interviews, according to their preference.
For the non-participants, anonymized living conditions and
care need levels were provided by the city. The number of
centenarian candidates varied by year (24-55). However, the
number of woman centenarians had increased through the
8-year surveyed period (31 and 42 for women, 10 and 9 for
men in 2014 and 2021). On average, every year 40 new cen-
tenarians were invited and 80% of them participated in the
survey. Among the functional variables, cognitive function
was estimated by proxies, which had a high correlation with
MMSE. No clear improving trend for nursing care level in
Japanese long-term care insurance, as measured by activities
of daily living and cognitive function rating, was observed.
Meanwhile, an improving trend for cognitive function was
observed among men but not among women. This might
be caused by the gender difference in the survival ratio that
frail women were more likely to survive. Future research
should investigate possible reasons for a cohort improve-
ment in Japanese centenarian men, and cognitive interven-
tion programs should particularly target women.
Abstract citation ID: igad104.1339
PROFILES OF TWO COHORTS OF NEAR-
CENTENARIANS AND CENTENARIANS: FINDINGS
FROM HONG KONG CENTENARIAN STUDY 1 AND 2
Bobo Hi-poLau, Hong Kong Shue Yan University, Hong
Kong, Hong Kong
Hong Kong launched its rst centenarian study in 2011
when there were just over 3,600 centenarians, and sub-
sequently, the second phase in 2021/22 when the popula-
tion of centenarians tripled. Both studies investigated the
multidimensional well-being of local older adults of Chinese
ethnicity aged 95 or above (near centenarians and centenar-
ians, NCCs). A comparison of the two cohorts of community
dwelling NCCs who lived with their family (2011: N=77;
2021/22: N=151) indicates a substantial drop in sensory
functions (2011 vs 2021/22: intact vision: 94.8% vs 40.4%;
intact hearing: 93.5% vs 53.6%), social activities (weekly or
more: 48.1% vs 40.4%), outdoor activities (weekly or more:
75.3% vs 45.3%), and independence in activities of daily
living (ADL) (no. of dependent task: 0.79 vs 2.79). Although
the prevalence of comorbidities was comparable (Charlson
age-adjusted comorbidity index: Mean = 2.7 vs 3.5), the
frailty and pre-frailty was considerably more common in
the 2021/22 cohort (55.3%; 39.0%) than the 2011 cohort
(50.6%; 23.4%). We also found disparate predictors for
health evaluations. Among the 2011 cohort, being male and
having better psychological well-being were related to more
favorable assessments of health compared to their peers.
Among the 2021/22 cohort, favorable peer-compared health
assessments were related to fewer ADL dependent tasks,
better psychological well-being, higher age and being female.
Despite the impact by COVID on the 2021/22 cohort, our
ndings alert policy makers and practitioners worldwide to
the growing number of community-dwelling adults of ad-
vanced age with considerable personal care and health needs.
Abstract citation ID: igad104.1340
COMPARING EARLIER- VERSUS LATER-BORN
CENTENARIAN COHORTS FROM THE HEALTH AND
RETIREMENT STUDY
GinaLee, and PeterMartin, Iowa State University, Ames,
Iowa, United States
The current study aimed to compare the health status of
earlier and later born centenarian cohorts. Using the data
from the Health and Retirement Study, we selected those
who survived to at least 98 years and divided them into
earlier (n=189) and later (n=304) cohorts. The birth year of
the earlier cohort ranged from 1890 to 1906, and the birth
year of the later cohort ranged from 1907 to 1920. We rst
recoded variables to examine health status when all parti-
cipants were at least 98 years old. To explore differences in
health status between earlier vs. later cohorts, we computed
t-tests/χ2 difference tests with activities of daily living, de-
pressive symptoms, self-report of health and health change
(SRHC), BMI, current smoking, drinking, cognition, and a
number of diseases. There were signicant differences in de-
pressive symptoms, SRHC, high blood pressure, and current
drinking between the earlier and later centenarian cohorts.
The later cohort had signicantly higher blood pressure,
more depressive symptoms, worse SRHC, and later cohorts
had a higher proportion of participants who currently con-
sumed alcohol. Finally, the results of two separate regression
analyses predicting depressive symptoms indicated that no
demographic or health variables of the earlier cohort signi-
cantly predicted depressive symptoms, but years of educa-
tion and current diagnosis of cancer signicantly predicted
depressive symptoms for the later cohort. Overall, the later
born cohort had a worse health status compared to the
earlier born cohort. This ndings highlights the need for
healthcare providers to pay attention to psychological health
among cancer-diagnosed centenarians.
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