Author Correction: WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response

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Corrections & amendments
Author Correction: WDR77 inhibits prion-like aggregation of
MAVS to limit antiviral innate immune response
Jiaxin Li, Rui Zhang, Changwan Wang, Junyan Zhu, Miao Ren, Yingbo Jiang,
Xianteng Hou, Yangting Du, Qing Wu, Shishi Qi, Lin Li, She Chen, Hui Yang &
Fajian Hou
The original version of this Article contained errors in the legends of Figures 1–4, 6, and 7.
The legend of Figure 1 originally incorrectly read ‘P-value was determined by two-tailed
Student’st-test.’The correct version replaces this sentence with ‘P-values were determined by
two-way ANOVA (Dunnett’stest)(f) or two-way ANOVA (Šídák’stest)(g,h,i,jand k).’
The legend of Figure 2 originally incorrectly read ‘P-value was determined by two-tailed
Student’st-test.’The correct version replaces this sentence with ‘P-values were determined by
two-way ANOVA (Šídák’stest)(a,b,d–f,i,j), ordinary one-way ANOVA (Tukey’stest)(h)ortwo-
way ANOVA (Tukey’stest)(l).’
The legend of Figure 2h originally incorrectly read ‘GFP-VSV titers were quantitated in
plaque assay (For d,VSV:*p= 0.0123, ****p< 0.0001 in s equence).’The correct version states
‘For h’instead of ‘For d’.
The legend of Figure 2l originally incorrectly read‘IFNB1 induction was measured by qPCR
(For l,IFNB1:****p< 0.0001, ***p=0.0001,nsp= 0.9957 in sequence).’The correct version states
‘***p= 0.0004’instead of ‘***p=0.0001’.
The legend of Figure 3 originally incorrectly read ‘P-value was determined by two-tailed
Student’st-test.’The correct version replaces this sentence with ‘P-values were determined by
two-way ANOVA (Šídák’stest)(a–c,h) or unpaired two-sided t-test (e).’
The legend of Figure 3h originally incorrectly read ‘IFNB1 induction was measured by qPCR
(ISRE:all****p< 0.0001; nsp= 0.9998).’The correct version states ‘IFNB1’instead of ‘ISRE’.
The legend of Figure 4 originally incorrectly read ‘P-value was determined by two-tailed
Student’st-test.’The correct version replaces this sentence with ‘P-values were determined by
two-way ANOVA (Šídák’stest)(i).’
The legend of Figure 4i originally incorrectly read ‘Cells were harvested at specified time
points post infection and IFNB1 induction was measured by qPCR (IFNB1:allnsp> 0.9999,
***p<0.0001,**p= 0.0018).’The correct version states ‘****p<0.0001’instead of ‘***p< 0.0001’.
The legend of Figure 6 originally incorrectly read ‘P-value was determined by two-tailed
Student’st-test.’The correct version replaces this sentence with ‘P-values were determined by
two-way ANOVA (Tukey’stest)(a,b,g), two-way ANOVA (Šídák’stest)(c) or two-way ANOVA
(Dunnett’stest)(d–f).’
The legend of Figure 7 originally incorrectly read ‘P-value was determined by two-tailed
Student’st-test.’The correct version replaces this sentence with ‘P-values were determined by
two-way ANOVA (Tukey’stest)(a,c), two-way ANOVA (Šídák’stest)(b,d,h) or Gehan-Breslow-
Wilcoxon test (f,g,i).’
The legend of Figure 7i originally incorrectly read ‘WT, Wdr77CKO and Mavs-/- mice (n=10
each) were injected intravenously with HSV at 1.5 × 108PFU per mouse, and the survival rates
were monitored for 15 days (*p= 0.445).’The correct version states ‘nsp=0.445’instead
of ‘*p=0.445’.
This has been corrected in both the PDF and HTML versions of the Article.
The original version of this Article contained errors in the legends of supplementary Fig-
ures 1–5, 7, and 8.
The legend of supplementary Figure 1 originally incorrectly read ‘Pvalue was determined
by two-tailed Student’st-test.’The correct version replaces this sentence with ‘Pvalues were
determined by two-way ANOVA (Dunnett’stest)(a,b).’
The legend of supplementary Figure 2 originally incorrectly read ‘Pvalue was determined
by two-tailed Student’st-test.’The correct version replaces this sentence with ‘Pvalues were
Correction to: Nature Communications
https://doi.org/10.1038/s41467-023-40567-5,
published online 10 August 2023
https://doi.org/10.1038/s41467-023-41712-w
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determined by unpaired two-sided t-test (b), ordinary one-way ANOVA
(Dunnett’stest)(e) or two-way ANOVA (Šídák’stest)(c,f,g).’
The legend of supplementary Figure 3 originally incorrectly read
‘Pvalue was determined by two-tailed Student’st-test.’The correct
version replaces this sentence with ‘Pvalues were determined by two-
way ANOVA (Šídák’stest)(b–e,g,i).’
The legend of supplementary Figure 4 originally incorrectly read
‘Pvalue was determined by two-tailed Student’st-test.’The correct
version replaces this sentence with ‘Pvalues were determined by two-
way ANOVA (Šídák’stest)(c,e,f,h).’
The legend of supplementary Figure 5 originally incorrectly read
‘Pvalue was determined by two-tailed Student’st-test.’The correct
version replaces this sentence with ‘Pvalues were determined by two-
way ANOVA (Šídák’stest)(g).’
The legend of supplementary Figure 7 originally incorrectly read
‘Pvalue was determined by two-tailed Student’st-test.’The correct
version replaces this sentence with ‘Pvalues were determined by
ordinary one-way ANOVA (Dunnett’stest)(e,f), two-way ANOVA
(Dunnett’stest)(g,i–k)ortwo-wayANOVA(Šídák’stest)(h).’
The legend of supplementary Figure 8 originally incorrectly read
‘Pvalue was determined by two-tailed Student’st-test.’The correct
version replaces this sentence with ‘Pvalues were determined by two-
way ANOVA (Dunnett’stest)(a,c,d(liver), e(lung), f(spleen, lung)),
two-way ANOVA (Tukey’stest)(b,d(spleen, lung), e(spleen), f(liver)),
or two-way ANOVA (Šídák’stest)(e(liver)).’
The HTML has been updated to include a corrected version of
the Supplementary Information.
The original version of this Article contained errors in the Statis-
tical Analysis in the Methods.
The Statistical Analysis in the Methods originally incorrectly read
‘Unpaired two-sided Student’st-test was used to analyze the sig-
nificance of mean values between groups. Kaplan–Meier survival ana-
lysis was used to analyze mouse survival data by two-sided log-rank
(Mantel–Cox) test.’
The correct version replaces these sentences with ‘Unpaired two-
sided Student’st-test, ordinary one-way ANOVA and two-way ANOVA
were used to analyze the significance of the differences between
groups. Survival data of mice were analyzed using Gehan-Breslow-
Wilcoxon test.’
This has been corrected in both the PDF and HTML versions of the
Article.
The original version of this Article contained an error in the
Source Data for Figure 2h.
The Source Data for Figure 2h originally incorrectly read ’35.6,
27.2 and 24.8’for VSV titer in WT, and ‘7.4, 6 and 8’forVSVtiterin
WDR77-/- and omitted measurements for MAVS-/-. The correct version
replaces these values with ‘410000000, 310000000 and 370000000’
for VSV titer in WT, and ‘44000000, 38000000 and 34000000’for
VSV titer in WDR77-/-,andadds‘1200000000, 1500000000 and
1300000000’for VSV titer in MAVS-/-.
The HTML has been updated to include a corrected version of the
Source Data.
Additional information
Supplementary information The online version contains supplementary material
available at
https://doi.org/10.1038/s41467-023-41712-w.
Open Access This article is licensed under a Creative Commons
Attribution 4.0 International License, which permits use, sharing,
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long as you give appropriate credit to the original author(s) and the
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indicated otherwise in a credit line to the material. If material is not
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© The Author(s) 2023
Corrections & amendments
nature communications (2023) 14:5960 | 2
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