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Sinoatrial Nodal Artery Arising from the Right Posterolateral Artery: A Rare Anatomical Variant

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We discuss a case report of a 66-year-old male with no prior cardiac history who presented to the hospital with persistent hiccups and shortness of breath. Following a positive nuclear stress test and cardiac catheterization, a rare anatomical variant of a sinoatrial nodal artery originating from the right posterolateral artery was revealed.
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MULTIMODALITY
MUSEUM IMAGE
Sinoatrial Nodal Artery
Arising from the Right
Posterolateral Artery:
A Rare Anatomical Variant
PARVIZ-ALI LOTFIAN, MD
ARUN UMESH MAHTANI, MD, MS
SEYED ZAIDI, MD
RICHARD GRODMAN, MD
ABSTRACT
We discuss a case report of a 66-year-old male with no prior cardiac history who presented
to the hospital with persistent hiccups and shortness of breath. Following a positive
nuclear stress test and cardiac catheterization, a rare anatomical variant of a sinoatrial
nodal artery originating from the right posterolateral artery was revealed.
CORRESPONDING AUTHOR:
Arun Umesh Mahtani, MD, MS
Department of Medicine,
Richmond University Medical
Center/Mount Sinai, Staten
Island, New York, US
arun.mahtani@nyu.edu
KEYWORDS:
coronary vessels; anatomical
variation; coronary circulation;
NSTEMI
TO CITE THIS ARTICLE:
Lotfian P-A, Mahtani AU, Zaidi
S, Grodman R. Sinoatrial Nodal
Artery Arising from the Right
Posterolateral Artery: A Rare
Anatomical Variant. Methodist
DeBakey Cardiovasc J.
2022;18(4):86-88. doi: 10.14797/
mdcvj.1109
*Author affiliations can be found in the back matter of this article
87Lotfian et al. Methodist DeBakey Cardiovasc J doi: 10.14797/mdcvj.1109
A 66-year-old male with no prior cardiac history
presented to the hospital with persistent hiccups, causing
shortness of breath. A nuclear stress test showed a fixed
perfusion defect involving the inferior wall, possibly due
to diaphragmatic attenuation artifact with no evidence
of stress-induced myocardial ischemia, and a mildly
decreased left ventricular ejection fraction of 44% (Figure 1).
Coronary angiography revealed two-vessel coronary artery
disease, 80% stenosis of the middle right coronary artery
(RCA), diffuse heavy calcification of the left anterior descen-
ding artery (LAD) involving the proximal and mid-portions
with 80% maximal stenosis, a small caliber left marginal,
and a sinoatrial (SA) nodal branch originating from the right
posterolateral artery (RPLA) (Figure 2 A, B).
Figure 1 Nuclear stress test showing fixed perfusion defect in the inferior wall possibly due to diaphragmatic motion artifact.
Figure 2 (A, B) Coronary artery angiography left anterior oblique view of the SA nodal artery arising from the right posterolateral artery.
SA: sinoatrial
88Lotfian et al. Methodist DeBakey Cardiovasc J doi: 10.14797/mdcvj.1109
TO CITE THIS ARTICLE:
Lotfian P-A, Mahtani AU, Zaidi S, Grodman R. Sinoatrial Nodal Artery Arising from the Right Posterolateral Artery: A Rare Anatomical Variant.
Methodist DeBakey Cardiovasc J. 2022;18(4):86-88. doi: 10.14797/mdcvj.1109
Submitted: 20 March 2022 Accepted: 01 August 2022 Published: 06 September 2022
COPYRIGHT:
© 2022 The Author(s). This is an open-access article distributed under the terms of the Attribution-NonCommercial 4.0 International
(CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any noncommercial medium, provided the original
author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.
Methodist DeBakey Cardiovascular Journal is a peer-reviewed open access journal published by Houston Methodist DeBakey Heart &
Vascular Center.
The SA nodal artery, a branch of the main coronary
arteries, supplies blood to the SA node. The SA node is also
known as the natural pacemaker of the heart. In 60% to 70%
of cases, its blood supply originates from the RCA, and in
20% to 30% from the LAD and left circumflex coronary
artery (LCX). The SA nodal artery provides vital oxygen
and nutrients to the SA node, which is a key component in
heart contraction that originates the initial electrical signal
for atrial contraction.1 When originating from the RCA, the
SA nodal artery most frequently arises at a mean distance
of 1.2 cm (range 0.2–2.2 cm) from its beginning.2 In less
than 1% of cases, the artery originates from the distal RCA.3
The posterolateral artery, also known as the posterior left
ventricular artery, arises from the RCA in a typical dominant
circulation. It is a terminal branch that supplies the inferior
portion of the heart along with the posterior descending
artery (PDA). It can also arise from the LAD or LCX.4 Based
on available data, this the first documented case of an SA
nodal artery originating from the RPLA.
COMPETING INTERESTS
The authors have no competing interests to declare.
AUTHOR AFFILIATIONS
Parviz-Ali Lotfian, MD orcid.org/0000-0002-3041-9342
Department of Medicine, Richmond University Medical Center/
Mount Sinai, Staten Island, New York, US
Arun Umesh Mahtani, MD, MS orcid.org/0000-0002-2101-7157
Department of Medicine, Richmond University Medical Center/
Mount Sinai, Staten Island, New York, US
Seyed Zaidi, MD orcid.org/0000-0003-0112-3769
Department of Cardiology, SUNY Downstate Medical Center,
Brooklyn, New York, US
Richard Grodman, MD orcid.org/0000-0002-2983-950X
Department of Cardiology, Richmond University Medical Center/
Mount Sinai, Staten Island, New York, US
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Anatomy, Thorax, Sinoatrial Nodal Artery; 2021 Jul [cited
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Anatomical aspects of the arterial blood supply to the
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S-shaped sinoatrial node artery. AJR Am J Roentgenol.
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articles/58074
... When the SANa emerges from the RCA, it tends to arise from its proximal segment (Hutchinson 1978;Sow et al. 1996;Vikse et al. 2016). Nevertheless, there are studies reporting an uncommon origin of the SANa from the more distal part of the RCA or even from its more distal branches (Futami et al. 2003;Hutchinson 1978;Kara et al. 2014;Kyriakidis et al. 1988;Lotfian et al. 2022;Nerantzis et al. 2011). ...
Article
Full-text available
Several studies reported anatomical variations in the sinoatrial node artery (SANa). Here, we report a rare variation in the origin of the SANa on a human adult male cadaver. During dissection, we identified the SANa originating from a large atrial branch of the right coronary artery (RCA). This branch originates at the level of the inferior border of the heart and courses upwards. The initial part of this vessel is tortuous, and then it follows a straight path parallel to the RCA along the anterior surface of the right atrium. After this part, the artery curves posteriorly and to the left until it reaches the lower border of the right auricle, where it closely approaches the RCA. Finally, the artery runs posteriorly and to the right to follow a course along the medial wall of the right auricle and right atrium to reach a location close to the region of the junction of the superior vena cava and right atrium, where it follows its path buried in the myocardium. After perforating the myocardium, this vessel gives rise to branches that are distributed to both atria in addition to the SANa. The SANa runs to the sinoatrial node in a precaval (anterior to the superior vena cava) course. We also tried to characterize the vessels radiologically. The knowledge of the anatomical variations of the SANa is of the utmost importance for cardiologists and heart surgeons to better understand cardiac disease and accurately plan and execute cardiac interventions and surgical procedures.
Article
Full-text available
Classic anatomical dissection of 150 hearts from adults aged 18 - 80 years was performed. The sinoatrial (SA) node artery was most frequently a large atrial branch of the right coronary artery (63%), arising at a mean distance of 1.2 cm (range 0.2 - 2.2 cm) from its beginning, with a mean external diameter of 1.7 mm (range 1 - 3 mm). In 37% of cases the SA node artery was a branch of the left coronary artery or one of its branches, with an initial mean external diameter of 2.2 mm (range 2 - 3 mm). The origin of the SA node artery was not related to coronary arterial dominance. The atrioventricular (AV) node artery was the first and longest inferior septal perforating branch of the right (90%) or left (10%) coronary artery, arising from the U- or V-shaped segment of the corresponding artery at the level of the crux cordis. Mean external diameter was 2 mm (range 1 - 3.5 mm). The origin of the AV node artery was dependent on coronary arterial dominance. Identification of the anatomical variants of the arterial blood supply to the SA and AV nodes may help in overcoming potential difficulties in treating arrhythmias and in mitral valve surgery.
Article
The purpose of this study was to use 64-MDCT to investigate the anatomic characteristics of the S-shaped variant of the sinoatrial node (SAN) artery and to describe the clinical implications of the findings in ablative procedures involving the left atrium. Coronary CT angiograms of 250 patients (152 men, 98 women; mean age, 60 +/- 12 [SD] years) were retrospectively analyzed for identification of the origin, number, anatomic course, mode of termination, and S-shaped variant of the SAN artery. At least one SAN artery was detected in 244 patients. The S-shaped variant was seen in 35 (14.3%) of these patients. Thirty-four of the variants (30.6% of all left SAN arteries) arose from the proximal to middle portion of the left circumflex artery (mean distance between the ostium of the left circumflex artery and the origin of S-shaped variant, 28.7 +/- 13.1 mm). The other variant (0.7% of all right SAN arteries) originated from the distal right coronary artery. The S-shaped variant was the only artery supplying the SAN in 28 (11.4%) of the patients. In patients with two arteries supplying the SAN, the right SAN artery and the S-shaped variant of the left SAN artery were seen together in seven patients. The S-shaped SAN artery (mean distance from atrial wall, 2.43 +/- 0.992 mm) had a predictable proximal course, lying in the posterior aspect in a groove between the orifices of the left superior pulmonary vein and the left atrial appendage close to the left atrial wall. The terminal segment of the artery approached the nodal tissue posterior to the superior vena cava in 22 patients, anterior to the vena cava in 10 patients, and through branches surrounding the vena cava in two patients. The S-shaped variation of the SAN artery is common and has a characteristic anatomic course. MDCT can be used to plan surgical and catheter-based left atrial interventions in which this artery is at risk of injury.
Grand Rapids, MI: Advanced Radiology Services Foundation; c2022. Weerakkody Y, Feger J. Posterior left ventricular artery
  • Radiopaedia
National Library of Medicine; c2022
  • M D Bethesda
  • K Nordick
  • B L Tedder
  • M R Zemaitis
Bethesda, MD: National Library of Medicine; c2022. Nordick K, Tedder BL, Zemaitis MR.
Sinoatrial Nodal Artery
  • Thorax Anatomy
Anatomy, Thorax, Sinoatrial Nodal Artery; 2021 Jul [cited