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© 2022 Indian Journal of Ophthalmology | Published by Wolters Kluwer - Medknow
Special Focus, Healthcare Professionals, Original Article
Vitamin B12 deciency in a large cohort of healthcare professionals across the
network of an eyecare organization in India
Sushma Nandyala*, Ashik Mohamed*, Archana Bhargava1, Sunita Chaurasia2, Sirisha Senthil3,
Pravin K Vaddavalli2
Access this article online
Website:
www.ijo.in
DOI:
10.4103/ijo.IJO_2823_21
PMID:
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Purpose:
Methods:
Results:
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P Conclusion:
Key words:
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Cite this article as: Nandyala S, Mohamed A, Bhargava A, Chaurasia S,
Senthil S, Vaddavalli PK. Vitamin B12 deciency in a large cohort of healthcare
professionals across the network of an eyecare organization in India. Indian
J Ophthalmol 2022;70:1718-21.
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Nandyala, et al.: Vitamin B12 deciency in eye care professionals
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Results
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shows the results of survey responses that were
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Discussion
Singla et al.[11]
Table1: Vitamin B12 in eyecare professionals. This table
summarizes age, gender, and vitamin B12 in employees
of a tertiary eyecare center with vitamin B12 deficient and
vitamin B12 normal levels
Parameter Vitamin B12
deficient
Vitamin B12
normal
Age(years), mean±SE 30.6±0.4 29.2±0.7
Male:Female(% males) 371:235(61.2%) 793:975(44.9%)
Vitamin B12 in all(pg/ml)
N(%)
Mean±SE
Minimum
Maximum
606(25.5%)
182.2±2.3
99
210
1768(74.5%)
340.8±18.9
211.1
2000
Vitamin B12 in males(pg/ml)
N(%)
Mean±SE
Minimum
Maximum
371(31.9%)
181.1±2.4
99
210
793(68.1%)
316.7±17.7
211.1
2000
Vitamin B12 in females(pg/
ml)
N(%)
Mean±SE
Minimum
Maximum
235(19.4%)
183.9±2.5
119
210
975(80.6%)
363.3±17.6
211.1
2000
(SE: standard error)
with a maximum population following a vegetarian diet.
professionals is very important for maintaining the health of
This
[15]
In our
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higher (P
levels.
in males.
Green et al.
Table2: Risk factor analysis of vitamin B12 in eyecare professionals. This table summarizes the responses to survey by
employees of a tertiary eye care centre
Question related to B12 deficiency All employees
(208 respondents)
Vitamin B12
deficient (n=81)
Vitamin B12
normal (n=127)
P
Strict vegan 41(19.7%) 18(22.2%) 23(18.1%) 0.43
Predominantly or strictly vegan 107(51.4%) 41(50.6%) 66(52.0%) 0.85
Family history* 15/110(13.6%) 8/45(17.8%) 7/65(10.8%) 0.29
Stomach or intestine diseases or infections 12(5.8%) 5(6.2%) 7(5.5%) 0.53
Immune disorders, human immunodeficiency
virus infection or chronic pancreatitis
15(7.2%) 4(4.9%) 11(8.7%) 0.31
Diabetes mellitus 6(2.9%) 1(1.2%) 5(3.9%) 0.26
Pregnancy and lactation** 2/92(2.2%) 1/35(2.9%) 1/57(1.8%) 0.73
Intake of medications 10(4.8%) 3(3.7%) 7(5.5%) 0.55
(*Available only from 110 respondents; **Applicable only on 92 respondents)
Table3: Regression analysis for vitamin B12 deficiency. This table summarizes the results of analysis of risk factors for
vitamin B12 deficiency by multilevel mixed effects regression analysis
Risk factor PCo‑efficient±standard error 95% confidence intervals
Age 0.56 ‑0.0005±0.0009 ‑0.0023 to 0.0013
Male gender <0.0001 0.10±0.02 0.07 to 0.13
Strict vegan 0.42 0.07±0.08 ‑0.10 to 0.23
Predominantly or strictly vegan 0.89 ‑0.10±0.07 ‑0.14 to 0.12
Family history 0.26 0.15±0.13 ‑0.11 to 0.41
Stomach or intestine diseases or infections 0.49 0.10±0.14 ‑0.18 to 0.38
Immune disorders, human immunodeficiency
virus infection or chronic pancreatitis
0.25 ‑0.15±0.13 ‑0.40 to 0.10
Diabetes mellitus 0.26 ‑0.22±0.20 ‑0.61 to 0.17
Pregnancy and lactation 0.73 0.12±0.35 ‑0.56 to 0.80
Intake of medications 0.41 ‑0.13±0.16 ‑0.43 to 0.18
Nandyala, et al.: Vitamin B12 deciency in eye care professionals
in old ages.
et al.
Conclusion
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Conicts of interest
References
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