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Chest-compression-only after drowning: a call for more research

Authors:
Editorial
Chest-compression-only
after
drowning:
a
call
for
more
research
Every
now
and
again
a
publication
appears
that
challenges
long-held
beliefs:
that
by
Fukunda
et
al.
from
Japan,
published
in
the
current
issue
of
Resuscitation,
is
surely
one
such.
1
The
authors
conclusion,
from
a
large
observational
study
of
cases
of
drowning,
is
that
there
was
no
difference
in
the
one-month
neurologically-favourable
survival
between
those
victims
who
received
bystander-initiated
conventional
CPR
and
those
who
received
compression-only
CPR.
Since
the
initial
Advisory
Statements
from
the
International
Liaison
Committee
on
Resuscitation
(ILCOR),
2
drowning
has
been
considered
a
special
circumstance
requiring
some
variation
from
standard
adult
CPR.
Because
drowning
produces
an
asphyxial
rather
than
a
primary
cardiac
arrest,
emphasis
has
been
put
on
the
need
for
early
ventilation.
Whilst
the
subsequent
guidelines
for
adult
basic
life
support
(BLS)
continued
to
advise
starting
resuscitation
with
rescue
breaths,
only
minor
differences
were
needed
for
drowning
victims,
such
as
giving
5
initial
breaths
and
performing
resuscitation
for
about
1
min
before
going
for
help.
It
also
meant
that
the
same
algorithm
could
be
used
for
drowning
as
for
paediatric
BLS.
34
From
2005
onwards,
however,
the
standard
adult
BLS
algorithm
changed
to
30
initial
chest
compressions
followed
by
2
rescue
breaths,
5
reflecting
the
recognition
that
most
cardiac
arrests
are
due
to
a
cardiac
cause
and
chest
compressions
are
of
primary
importance.
In
parallel
with
this
came
publications
suggesting
that
chest
compres-
sions
alone
were
at
least
as
effective
as
combined
compression
and
ventilation
in
most
cases
of
adult
cardiac
arrest.
69
This
created
a
problem
for
those
responsible
for
advising
on
resuscitation
following
drowning,
as
compression-first
was
not
consistent
with
the
need
urgently
to
ventilate
a
hypoxic
victim.
Several
publications
appeared,
emphasising
this
need
and
calling
for
more
recognition
of
drowning
as
requiring
specific
attention
and
management.
1012
The
latest
(2015)
European
Resuscitation
Council
guidelines
still
recommend
combined
compression
and
ventilation
for
all
cases
of
cardiac
arrest,
13
but
recognise
that
the
far
simpler
chest-
compression-only
is
an
effective
alternative
for
dispatcher-
directed
(telephone)
CPR.
Dispatchers
are
advised
to
offer
compression-only
CPR
for
untrained
rescuers
in
all
cases
of
cardiac
arrest
except
children,
when
instruction
on
rescue
breaths
should
be
given
as
well.
Surprisingly,
drowning
is
not
included
as
a
similar
exception,
implying
that
dispatchers
should
offer
compres-
sion-only
CPR.
The
guidelines
do
contain
a
much-expanded
section
on
water
rescue
and
drowning,
including
a
unique
treatment
algorithm,
but
this
is
specifically
for
rescuers
with
a
duty
to
respond.
14
But
what
about
the
bystander
without
such
a
duty?
Fukunda
et
al.
suggest
that
it
is,
in
fact,
reasonable,
for
dispatchers
to
offer
compression-only
CPR.
In
spite
of
the
fact
there
has
not
been
any
previous
randomised
clinical
trial,
or
even
observational
study
of
conventional
versus
compression-only
CPR
following
drowning,
1
experts
in
the
field
have
argued
that
there
is,
a
priori,
a
case
for
combined
ventilation
and
compression
based
on
the
fact
that
drowning
is
an
asphyxial
event.
1012
A
Devils
Advocate*,
15
however,
could
argue
that
there
is
a
good
case
for
considering
the
results
of
this
new
study
as
a
call
for
further
research,
because:
-
dispatcher-
and
mass-teaching
of
compression-only
CPR
has
been
shown
to
improve
overall
results
from
out-of-hospital
bystander
resuscitation.
16
Might
this
not
also
be
the
case
for
drowning
itself?
-
by
no
means
every
victim
of
cardiac
arrest
in
the
water
has
suffered
primary
drowning.
17
-
at
least
in
developed
countries,
cardiac
causes
of
cardiac
arrest
are
much
more
common
than
drowning:
the
principle
of
the
greatest
good
for
the
greatest
number’
should,
therefore,
apply.
18
-
even
if
standard
CPR
(with
ventilation)
is
the
management
of
choice
for
drowning
victims,
surely
it
is
better
for
the
untrained
rescuer
to
be
instructed
to
do
something
simple
than
to
be
unable
to
do
anything?
Fukunda
et
al.,
quite
rightly,
admit
that
there
are
weaknesses
in
their
study,
mainly
related
to
a
lack
of
data
on
specific
features
of
drowning,
such
as
water
temperature,
submersion
duration,
and
body
of
water.
These
data
are
not
included
in
reports
according
to
Utstein
reporting
of
out-of-hospital
cardiac
arrest
19
although
they
are
in
the
Utstein-style
reporting
for
drowning.
20
In
addition,
both
reporting
styles
only
ask
whether
or
not
bystander
CPR
included
rescue
breathing
as
subset
or
supplementary
information.
Future
retrospective
researchers
will
have
no
choice
but
to
use
what
data
exist,
but
prospective
studies
should
be
designed
to
avoid
these
deficiencies.
We
are
about
a
year
away
from
a
5-yearly
review
of
the
resuscitation
guidelines,
and
already
working
groups
are
reviewing
current
literature.
This
paper
will
undoubtedly
be
of
interest.
How
might
it
change
the
management
of
drowning?
Probably
very
little,
particularly
for
rescuers
with
a
duty
of
care.
It
does
seem
a
little
strange
that
guidelines
for
R
E
S
U
S
C
I
T
A
T
I
O
N
1
4
5
(
2
0
1
9
)
1
9
4
1
9
5
Available
online
at
www.sciencedirect.com
Resuscitation
jou
r
n
al
ho
m
epag
e:
ww
w.els
evier.c
o
m/lo
c
ate/res
u
sc
itat
ion
dispatcher-directed
CPR
after
drowning
are
currently
compression-only;
it
is
even
possible
that
this
was
an
oversight.
The
results
of
the
present
study,
however,
suggest
that
the
advice
may,
in
fact,
be
correct.
The
appropriate
working
group
should
take
Fukunda
and
colleagues
research
into
consideration
when
reviewing
the
section.
We
have
been
set
a
challenge!
In
this
day
of
evidence-based
medicine,
we
need
to
be
open
to
all
ideas
that
could
possibly
result
in
a
significant
change
in
our
practice
of
resuscitation
medicine.
Who
will
be
first
to
try
and
replicate
these
database
results?
*Devils
Advocate
is
someone
who
takes
a
position
they
do
not
necessarily
agree
with
for
the
sake
of
debate
or
to
explore
the
thought
further.
Conflict
of
interest
statement
The
author
holds
honorary
(unpaid)
roles
in
the
European
Resuscita-
tion
Council,
Resuscitation
Council
(UK)
and
Royal
Life
Saving
Society
UK.
R
E
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2019;145:16775.
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BJ,
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Zhan
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cardiopulmonary-resuscitation-for-drowning/..
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Anthony
J.
Handley
Cambridge,
UK
E-mail
address:
tony.handley@outlook.com
(A.
Handley).
http://dx.doi.org/10.1016/j.resuscitation.2019.09.029
©
2019
The
Author.
Published
by
Elsevier
B.V.
This
is
an
open
access
article
under
the
CC
BY-NC-ND
license
(http://creativecommons.org/
licenses/by-nc-nd/4.0/).
R
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C
I
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1
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)
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... Only three studies in this review evaluated CPR methods [20][21][22]. The role of CPR with ventilation compared to only compression remains unclear, with varied findings reported in these three studies and those published since the review [23,24]. Automatic external defibrillator (AED) use was evaluated in only three studies, with mixed results [20,25,26]. ...
Article
Background: Identification of predictors of outcome at the scene of drowning events could guide prevention, care and resource utilization. This review aimed to describe where, what and how scene predictive factors have been evaluated in drowning outcome studies. Methods: We reviewed studies reporting scene drowning predictors published between 2003 and 2019. Data extraction included study populations, data sources, predictor factors (victim, incident, rescue, resuscitation and hospital-related), outcome measures and type of analyses. Results: Of 49 studies, 87.6% were from high-income countries, 57.1% used data from only one source (92.9% of these from either hospital or EMS), 73.5% included cases who received medical care and 53.1% defined outcomes as survival or death. A total of 78 different factors were studied; the most commonly studied group of factors described victim demographics, included in 42 studies (85.7%), followed by resuscitation factors, included in 30 studies (61.2%). Few studies described rescue (6.1%). The most frequent statistically significant single predictors of outcome known at the scene were submersion duration (evaluated in 19, predictor in 14) and age (evaluated in 31, predictor in 16). Only 38.7% of studies employed multivariable methods. Conclusions: Gaps to be addressed in drowning outcomes research include data from low- and middle-income countries, standardized definition of factors to allow evaluation across studies, inclusive study populations that can be generalized beyond those receiving medical care, study rescue and resuscitation factors, use of more meaningful outcomes (survival with good neurologic status) and advanced analyses to identify which factors are true predictors versus confounding variables.
... We wholeheartedly support the call for research on drowning resuscitation in Tony Handley's "devil's advocacy" relating to Fukuda's drowning study 1,2 . Advocacy statements on drowning research have been made since the beginning of the century, including in the World Health Organisation's identification of drowning as a neglected issue. ...
Chapter
Full-text available
Drowning is usually related to a leisure situation that turned into a dramatic, life-threatening event. Parents, friends, relatives, babysitters, or guardians may feel not only profound loss and grief but also either guilt for failure to fulfill protection responsibilities or intense anger at others who did not provide adequate supervision or medical care. Nevertheless, drowning is a neglected public health problem. 1 Each year, drowning is responsible for an estimated 500,000 deaths around the world. The exact number is unknown because many deaths go unreported. 2 Age, gender, alcohol use, socioeconomic status (as measured by income and/or education), and lack of supervision are key risk factors for drowning. Considering all ages, males die 5 times more often from drowning than females. An estimated 40% to 45% of deaths occur during swimming. 3 Young children, teenagers, and older adults are at highest risk of drowning. 4 In the age group of 5 to 14 years, drowning is the leading cause of death worldwide among males and the fifth leading cause of death for females. 4 The patterns of drowning are highly dependent on geographic factors. In the United States, drown-ing is the third most common cause of unintentional injury death for all ages and ranks second for people aged 5 to 44 years. 5 Considering all deaths by drowning in United States (4390 in 1993), 53% occurred in swimming pools. 3
Article
Background: Great emphasis has been placed on rescue breathing in out-of-hospital cardiac arrest (OHCA) due to drowning. However, there is no evidence about the effect of rescue breathing on neurologically favorable survival after OHCA due to drowning. The aim of this study is to examine the effect of bystander-initiated conventional (with rescue breathing) versus compression-only (without rescue breathing) cardiopulmonary resuscitation (CPR) in OHCA due to drowning. Methods: This nationwide population-based observational study using prospectively collected government-led registry data included patients with OHCA due to drowning who were transported to an emergency hospital in Japan between 2013 and 2016. The primary outcome was one-month neurologically favorable survival. Results: The full cohort (n = 5,121) comprised 2,486 (48.5%) male patients, and the mean age was 72.4 years (standard deviation, 21.6). Of these, 968 (18.9%) received conventional CPR, and 4,153 (81.1%) received compression-only CPR. 928 patients receiving conventional CPR were propensity-matched with 928 patients receiving compression-only CPR. In the propensity score-matched cohort, one-month neurologically favorable survival was not significantly different between the two groups (7.5% in the conventional CPR group vs. 6.6% in the compression-only CPR group; risk ratio, 1.15; 95% confidence interval, 0.82-1.60; P = 0.4147). This association was consistent across a variety of subgroup analyses. Conclusions: Among patients with OHCA due to drowning, there were no differences in one-month neurologically favorable survival between bystander-initiated conventional and compression-only CPR groups, although several important data (e.g., water temperature, submersion duration, or body of water) could not be addressed. Further study is warranted to confirm our findings.
Article
Background: Out-of-hospital cardiac arrest (OHCA) is a major cause of death worldwide. Cardiac arrest can be subdivided into asphyxial and non asphyxial etiologies. An asphyxia arrest is caused by lack of oxygen in the blood and occurs in drowning and choking victims and in other circumstances. A non asphyxial arrest is usually a loss of functioning cardiac electrical activity. Cardiopulmonary resuscitation (CPR) is a well-established treatment for cardiac arrest. Conventional CPR includes both chest compressions and 'rescue breathing' such as mouth-to-mouth breathing. Rescue breathing is delivered between chest compressions using a fixed ratio, such as two breaths to 30 compressions or can be delivered asynchronously without interrupting chest compression. Studies show that applying continuous chest compressions is critical for survival and interrupting them for rescue breathing might increase risk of death. Continuous chest compression CPR may be performed with or without rescue breathing. Objectives: To assess the effects of continuous chest compression CPR (with or without rescue breathing) versus conventional CPR plus rescue breathing (interrupted chest compression with pauses for breaths) of non-asphyxial OHCA. Search methods: We searched the Cochrane Central Register of Controlled Trials (CENTRAL; Issue 1 2017); MEDLINE (Ovid) (from 1985 to February 2017); Embase (1985 to February 2017); Web of Science (1985 to February 2017). We searched ongoing trials databases including controlledtrials.com and clinicaltrials.gov. We did not impose any language or publication restrictions. Selection criteria: We included randomized and quasi-randomized studies in adults and children suffering non-asphyxial OHCA due to any cause. Studies compared the effects of continuous chest compression CPR (with or without rescue breathing) with interrupted CPR plus rescue breathing provided by rescuers (bystanders or professional CPR providers). Data collection and analysis: Two authors extracted the data and summarized the effects as risk ratios (RRs), adjusted risk differences (ARDs) or mean differences (MDs). We assessed the quality of evidence using GRADE. Main results: We included three randomized controlled trials (RCTs) and one cluster-RCT (with a total of 26,742 participants analysed). We identified one ongoing study. While predominantly adult patients, one study included children. Untrained bystander-administered CPRThree studies assessed CPR provided by untrained bystanders in urban areas of the USA, Sweden and the UK. Bystanders administered CPR under telephone instruction from emergency services. There was an unclear risk of selection bias in two trials and low risk of detection, attrition, and reporting bias in all three trials. Survival outcomes were unlikely to be affected by the unblinded design of the studies.We found high-quality evidence that continuous chest compression CPR without rescue breathing improved participants' survival to hospital discharge compared with interrupted chest compression with pauses for rescue breathing (ratio 15:2) by 2.4% (14% versus 11.6%; RR 1.21, 95% confidence interval (CI) 1.01 to 1.46; 3 studies, 3031 participants).One trial reported survival to hospital admission, but the number of participants was too low to be certain about the effects of the different treatment strategies on survival to admission(RR 1.18, 95% CI 0.94 to 1.48; 1 study, 520 participants; moderate-quality evidence).There were no data available for survival at one year, quality of life, return of spontaneous circulation or adverse effects.There was insufficient evidence to determine the effect of the different strategies on neurological outcomes at hospital discharge (RR 1.25, 95% CI 0.94 to 1.66; 1 study, 1286 participants; moderate-quality evidence). The proportion of participants categorized as having good or moderate cerebral performance was 11% following treatment with interrupted chest compression plus rescue breathing compared with 10% to 18% for those treated with continuous chest compression CPR without rescue breathing. CPR administered by a trained professional In one trial that assessed OHCA CPR administered by emergency medical service professionals (EMS) 23,711 participants received either continuous chest compression CPR (100/minute) with asynchronous rescue breathing (10/minute) or interrupted chest compression with pauses for rescue breathing (ratio 30:2). The study was at low risk of bias overall.After OHCA, risk of survival to hospital discharge is probably slightly lower for continuous chest compression CPR with asynchronous rescue breathing compared with interrupted chest compression plus rescue breathing (9.0% versus 9.7%) with an adjusted risk difference (ARD) of -0.7%; 95% CI (-1.5% to 0.1%); moderate-quality evidence.There is high-quality evidence that survival to hospital admission is 1.3% lower with continuous chest compression CPR with asynchronous rescue breathing compared with interrupted chest compression plus rescue breathing (24.6% versus 25.9%; ARD -1.3% 95% CI (-2.4% to -0.2%)).Survival at one year and quality of life were not reported.Return of spontaneous circulation is likely to be slightly lower in people treated with continuous chest compression CPR plus asynchronous rescue breathing (24.2% versus 25.3%; -1.1% (95% CI -2.4 to 0.1)), high-quality evidence.There is high-quality evidence of little or no difference in neurological outcome at discharge between these two interventions (7.0% versus 7.7%; ARD -0.6% (95% CI -1.4 to 0.1).Rates of adverse events were 54.4% in those treated with continuous chest compressions plus asynchronous rescue breathing versus 55.4% in people treated with interrupted chest compression plus rescue breathing compared with the ARD being -1% (-2.3 to 0.4), moderate-quality evidence). Authors' conclusions: Following OHCA, we have found that bystander-administered chest compression-only CPR, supported by telephone instruction, increases the proportion of people who survive to hospital discharge compared with conventional interrupted chest compression CPR plus rescue breathing. Some uncertainty remains about how well neurological function is preserved in this population and there is no information available regarding adverse effects.When CPR was performed by EMS providers, continuous chest compressions plus asynchronous rescue breathing did not result in higher rates for survival to hospital discharge compared to interrupted chest compression plus rescue breathing. The results indicate slightly lower rates of survival to admission or discharge, favourable neurological outcome and return of spontaneous circulation observed following continuous chest compression. Adverse effects are probably slightly lower with continuous chest compression.Increased availability of automated external defibrillators (AEDs), and AED use in CPR need to be examined, and also whether continuous chest compression CPR is appropriate for paediatric cardiac arrest.
Article
Utstein-style guidelines contribute to improved public health internationally by providing a structured framework with which to compare emergency medical services systems. Advances in resuscitation science, new insights into important predictors of outcome from out-of-hospital cardiac arrest, and lessons learned from methodological research prompted this review and update of the 2004 Utstein guidelines. Representatives of the International Liaison Committee on Resuscitation developed an updated Utstein reporting framework iteratively by meeting face to face, by teleconference, and by Web survey during 2012 through 2014. Herein are recommendations for reporting out-of-hospital cardiac arrest. Data elements were grouped by system factors, dispatch/recognition, patient variables, resuscitation/postresuscitation processes, and outcomes. Elements were classified as core or supplemental using a modified Delphi process primarily based on respondents’ assessment of the evidence-based importance of capturing those elements, tempered by the challenges to collect them. New or modified elements reflected consensus on the need to account for emergency medical services system factors, increasing availability of automated external defibrillators, data collection processes, epidemiology trends, increasing use of dispatcher-assisted cardiopulmonary resuscitation, emerging field treatments, postresuscitation care, prognostication tools, and trends in organ recovery. A standard reporting template is recommended to promote standardized reporting. This template facilitates reporting of the bystander-witnessed, shockable rhythm as a measure of emergency medical services system efficacy and all emergency medical services system – treated arrests as a measure of system effectiveness. Several additional important subgroups are identified that enable an estimate of the specific contribution of rhythm and bystander actions that are key determinants of outcome.