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Hair Loss after Dengue virus infection Report of 3 cases

Authors:
  • CAECI - Centro de Aperfeiçoamento Educacional e Científico

Abstract

References: Tan PC, RajasingamG, Devi S, Omar SZ. Dengue infection in pregnancy: prevalence, vertical transmission, and pregnancy outcome. Obstet Gynecol. 2008;111(5):1111-1117. Marovich et al. Human Dendritic Cells as targets of Dengue Virus Infection. Journal of Investigative Dermatology. 2001;6:219-224. Rothman AL, Dengue: defining protective versus pathologi immunity. J Clin Invest. 2004; 113(7):946-951. Murrell S, Wy SC, Butler M. Review of dengue infection and the development of a vaccine. Biotechnol Adv. 2011;29(2):239-247. Barreto ML, Teixeira MG, Bastos FI, Ximenes RA, Barata RB, Rodrigues LC. Successes and failures in the control of infections diseases in Brazil: social and enviromental context, policies, interventions, and research needs.
Ademir Carvalho Leite Junior Fabiana Padovez
Clínica Dr Ademir Júnior Espaço de Medicina e Saúde
Universidade Anhembi Morumbi SP/SP - Brasil
References:
Tan PC, RajasingamG, Devi S, Omar SZ. Dengue infection in pregnancy: prevalence, vertical transmission, and pregnancy outcome. Obstet Gynecol.
2008;111(5):1111-1117.
Marovich et al. Human Dendritic Cells as targets of Dengue Virus Infection. Journal of Investigative Dermatology. 2001;6:219-224.
Rothman AL, Dengue: defining protective versus pathologi immunity. J Clin Invest. 2004; 113(7):946-951.
Murrell S, Wy SC, Butler M. Review of dengue infection and the development of a vaccine. Biotechnol Adv. 2011;29(2):239-247.
Barreto ML, Teixeira MG, Bastos FI, Ximenes RA, Barata RB, Rodrigues LC. Successes and failures in the control of infections diseases in Brazil: social and
enviromental context, policies, interventions, and research needs. Lancet. 2011; 377(9780):1877-1889.
Hair Loss after Dengue virus infection
Report of 3 cases
Dengue is a disease common in tropical and
subtropical countries caused by an arbovirus.
The virus is transmitted by the Aedes aegypti
mosquito and can cause clinical
manifestations in the infected organism for a
period of approximately seven days after the
period of incubation (3 to 14 days). There are
four types of dengue virus: DENV-1, DENV-2,
DENV-3 and DENV-4. The World Health
Organization estimates that about 50 million
infections occur annually, with approximately
500 thousand cases of dengue hemorrhagic
fever and 21 thousand deaths, mostly in
children.
Dengue can affect children and adults and its
most frequent clinical manifestation is high
fever. Complications such as hemorrhagic
fever that is related with thrombocytopenia (<=
100.000/mm3) and hemorrhagic trends
evidenced by petechiae, ecchymoses, purpura
and digestive tract mucous bleeding may
occur. Plasma extravasation may occur due to
increased capillary permeability (identified by
a20% increase in hematocrit compared to
baseline, low hematocrit of 20% after
appropriate treatment, pleural effusion, ascites
and hypoproteinemia).
.
P-34
In 2010 we evaluated and treated three adult
females experiencing severe hair loss (Acute
Telogen Effluvium) 2 months after being
infected by dengue, two of them with history of
dengue hemorrhagic fever.
The clinical examination of scalp and hair of
the patients showed intense diffuse hair loss.
The event of dengue infection and the
exclusion of other diagnostic possibilities
accused acute telogen effluviun caused by
dengue fever.
The suggested treatment for these patients
was observation and regular use of lotion with
2% of minoxidil twice a day until the
disappearance of the hair loss symptoms and
total recovery of hair that occurred 8 to 11
months after infection.
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