No full-text available
To read the full-text of this research,
you can request a copy directly from the authors.
Paracoccidioidomycosis: an unusual presentation in a young girl disclosing an unnoted HIV-infection
... The most frequent endemic systemic mycosis in South America is PCM, and Brazil is the country with the largest number of cases. 1 Despite the considerable prevalence of PCM and HIV-1 infection in endemic areas, there are relatively few reported cases of association between these 2 diseases. [2][3][4] The involvement of the visual apparatus because of PCM occurs secondary to systemic disease and is uncommon, most frequently affecting the eyelids and conjunctiva. 5 To our knowledge, this is the first case report of lacrimal system obstruction by P. brasiliensis in a patient with unnoted HIV-1 infection. ...
... This type of co-infection occurs in 0.02% to 1.5% of individuals with PCM, and possible explanations for the low frequency of association between PCM and HIV-1 include cotrimoxazole prophylaxis and the use of azoles for candidiasis. 2,3 P. brasiliensis infection in the eyelids and conjunctiva, and also choroid involvement were previously reported in patients with AIDS/PCM co-infection. 5 However, the involvement of the lacrimal system in patients with PCM with or without AIDS had not yet been reported. ...
... Quelques cas de migrations d'Ozurdexs en chambre antérieure ont été décrits chez des patients aphakes ou ayant un cristallin artificiel a fixation irienne. [3][4][5] A notre connaissance, il s'agit du premier cas décrit dans la littérature chez un patient pseudophake ayant un implant a fixation sclérale. Il nous semble intéressant de ne pas méconnaître une telle complication chez les patients vitrectomisés avec une ...
... In immunosuppressed patients, the clinical picture of histoplasmosis, cryptococcosis, paracoccidioidomycosis and even disseminated sporotrichosis converges to similar manifestations: a relatively short history of fever, lack of appetite, weight loss, and asthenia, followed by or concomitant with the appearance of skin lesions showing an acneiform, disseminated ulcerated papular-nodular or ulcerated-necrotic pattern, frequent facial involvement, associated with signs and symptoms of systemic involvement. 3,9 The prognosis of paracoccidioidomycosis is reserved in post-transplant cases, resulting from the use and maintenance of immunosuppressants, disease dissemination and possible complications associated with therapy. The options of itraconazole, sulfamethoxazoletrimethoprim, amphotericin B deoxycholate, or liposomal are defined by the overall clinical picture and availability. ...
Paracoccidioidomycosis is an endemic systemic mycosis caused by Paracoccidioides brasiliensis complex and P. lutzii. It is a rare disease in non-HIV-induced immunosuppressed individuals. In organ transplant recipients, it is more frequently associated with immunosuppression after kidney transplantation. In a liver transplant patient, only one case has been published in the literature to date. The present report comprises the case of a 47-year-old female patient with disseminated skin lesions associated with signs and symptoms of systemic involvement of paracoccidioidomycosis that manifested one year after liver transplantation and under an immunosuppression regimen with tacrolimus and mycophenolate mofetil.
... 2,4 It is known that the immunological changes characteristic of pregnancy can exacerbate the natural history of systemic fungal infections; however, that is well accepted when associated with HIV infection. 3,4 Herein, the patient was in the sixth month of pregnancy and showed no immunological changes. These facts make the diagnosis of the systemic fungal infection unexpected. ...
... 6 Da mesma forma, observa-se em indivíduos imunossuprimidos pela infecção pelo HIV/Aids, ou iatrogenicamente, que o fungo adquire comportamento de agente oportunista, com evolução e aspectos clínicos distintos. 7 A relação entre o P. brasiliensis e o meio ambiente ainda não está totalmente esclarecida, mas acredita-se que o micélio seja a forma saprobiótica do fungo na natureza que, sob certas condições, produziria conídios, estruturas de reprodução assexuada e de propagação da espécie. Os conídios, presentes no solo, água e plantas, à temperatura ambiente, são considerados formas infectantes. ...
Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America, among immunecompetent patients. It's caused by the dimorphic fungus Paracoccidioiddes brasiliensis. Investigations regarding its immunopathogenesis are very important in the understanding of aspects related to natural history, as the protective immunity, and the relationship between host and parasite; also favoring the knowledge about clinical patterns and the elaboration of therapeutic strategies. The disease clinical polymorphism depends, at least, of the immune response profile according to the tissue and blood released citokynes, resulting in tissue damage.
Paracoccidioidomycosis is an acute - to chronic systemic mycosis caused by fungi of
the genus Paracoccidioides. Due to its frequent tegument clinical expression,
paracoccidioidomycosis is an important disease for dermatologists, who must be
up-to-date about it. This article focuses on recent epidemiological data and
discusses the new insights coming from molecular studies, as well as those related to
clinical, diagnostic and therapeutic aspects. In the latter section, we give
particular attention to the guideline on paracoccidioidomycosis organized by
specialists in this subject.
Paracoccidioidomycosis (PCM) is a systemic, endemic fungal disorder restricted to Latin America (Mexico to Argentina); Brazil accounts for the largest number of cases. Imported cases diagnosed in North America, Europe and Asia represent patients who had previously lived in recognized endemic areas. Paracoccidioides brasiliensis, the etiologic agent, is a thermally dimorphic fungus that in patients and cultures at 37 ° C adopts a yeast form while at lower temperatures it behaves as a mold that bears the infectious conidia. PCM has a peculiar gender distribution with preference for adult males at a ratio of ≥11 to 1. PCM afflicts predominantly adult males engaged in agriculture. It is mostly a chronic disease with acute/subacute cases accounting for less than 15 % of all reports. Specific diagnosis is established late and although available therapy is usually successful in controlling the fungal infection, patients who survive usually develop residual fibrotic lesions that heavily impair their quality of life.
ResearchGate has not been able to resolve any references for this publication.