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S1 Table. Most abundant transcripts in induced and partially silenced cells of the
conditional M. tuberculosis c-otsB2-tet-on mutant. Cells were cultivated in presence of
200 ng/ml (100% growth relative to WT) or 30 ng/ml ATc (ca. 30% residual growth relative to
WT) for 7 days. rRNA-depleted samples were analyzed by RNAseq. RPKM, reads per
kilobase of transcript per million mapped reads.
Average trimmed RPKM
Rv ID
Description
Size (bp)
partially
silenced
induced
Most abundant in partially silenced cells
RVnc0046
ssr
368
151348.7
301903.6
RVnc0036a
MTS2823
300
123055.7
856824.6
Rvnt03
leuT
83
45327.2
152403.1
Rvns01
rnpB
307
21422.5
66901.6
Rv1398c
vapB10
258
17890.8
13075.9
RVnc0006
C8
128
15441.2
122028.7
RVnc0036
MTS1338
117
13833.1
277857.0
Rvnt12
aspT
74
13515.8
44517.0
Rvnt38
metU
74
11107.0
15902.2
Rv1872c
lldD2
1245
11023.0
7265.6
Rvnt44
serT
89
9276.9
27669.3
RVnc0024
mcr7
350
6370.0
5655.6
Rvnr03
rrf
115
6344.6
11202.3
RVnc0004
B11
93
5964.1
17216.6
Rvnt37
alaU
73
5085.8
16496.5
Most abundant in induced cells
RVnc0036a
MTS2823
300
123055.7
856824.6
RVnc0046
ssr
368
151348.7
301903.6
RVnc0036
MTS1338
117
13833.1
277857.0
Rvnt03
leuT
83
45327.2
152403.1
RVnc0006
C8
128
15441.2
122028.7
Rvns01
rnpB
307
21422.5
66901.6
Rvnt12
aspT
74
13515.8
44517.0
Rvnt44
serT
89
9276.9
27669.3
RVnc0004
B11
93
5964.1
17216.6
Rvnt37
alaU
73
5085.8
16496.5
Rvnt38
metU
74
11107.0
15902.2
Rv1398c
vapB10
258
17890.8
13075.9
Rvnr03
rrf
115
6344.6
11202.3
RVnc0013
mcr11
131
3149.4
7376.8
Rv1872c
lldD2
1245
11023.0
7265.6