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MICs data for the synergistic antifungal combinations and their FIC index at different time points. (DOC)

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Ketoconazole 16h 24h 48h

Caspo* FIC

Index

Caspo FIC

Index

Caspo FIC

Index

0.032 <0.0059 >2 <0.0059 >2 0.38-0.75 0.5-1

0.016 <0.0059 >1 <0.0059 >1 0.38-0.75 0.5-1

0.008 0.094-0.19 0.5-1 0.19-0.38 0.5-1 0.75 0.5-1

0.004 0.75 0.5-1 0.75 0.5-1 0.75-1.5 0.5-1

0.002 1.5 >1 1.5 >1 1.5 >1

0.001 1.5 >1 1.5 >1 1.5 >1

0.0005 1.5 >1 1.5 >1 1.5 >1

*: Caspo: caspofungin

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Article

July 2016

Abstract