It is significant to research the metallurgical performance of mold because it's the heart of the continuous caster. Many high-grade steels are made in bloom mold, so this paper set a coupled mathematical model including fluid flow, heat transfer with solidification, inclusion movement in bloom mold with area of 380mm*280mm. Based on this model, the effect of three kinds of submerged entry nozzles with one-port, two-port and four-port on the fluid flow field, temperature field, solidified shell thickness profile and inclusions movement was investigated respectively. Results show that one-port nozzle makes the thickness of solidified shell increase gradually and uniformly because there is no impingement on shell, but it causes a deeper impinging jet which results in an only 7% removal rate of Al2O3 inclusions with size of 50 mu m and a higher inclusion concentration within 25-35mm beneath the bloom. Two-port nozzle causes a strong impingement on the narrow face which results in a thinner and worse shell growing there, but causes a lower impinging depth which results in a 17% removal rate of inclusions and a higher inclusion concentration within 10-20mm beneath the bloom. Four-port nozzle can weaken the jet impingement on shell and promote the flotation of inclusions because of the formation of several spiral rising flows in mold. The removal rate of inclusions is 25% by using four-port nozzle which is worth to popularize in practice.