This paper is focused on solving engineering optimization problems, which contain often real and integer variables, a number of local extremes, multiple optimality criteria and disciplines. In latter case the conventional approaches based on traditional gradient technique fail or perform poorly. In the current study, an optimization approach that integrates meta-modeling and hybrid genetic algorithm (HGA) is developed. The methodology proposed is validated on following practical examples: optimal design of composite bathtub (large composite plastics), design of car frontal protection system.