Detailed Statistics on FDR from Simulation Study. The table displays the 5th, 25th, 50th, 75th, and 95th quantiles of observed FDR for simulation runs. Observed FDR was calculated with and without variance filtering for both FDR methods (Benjamini-Hochberg and q-value) using a stated FDR level of 0.05. Both dependent and independent cases were considered over a range of π0 values, where π0 is the
... [Show full abstract] proportion of genes which are truly not differentially expressed.