Correct inference on the coefficients of dynamic regression models depends in a crucial manner on the degree of persistence of the explanatory variables. While standard asymptotic inference applies in OLS regressions with stationary regressors, the limiting distributions are nonstandard in the presence of integrated regressors. The paper studies test procedures that are robust in the sense that their asymptotic null distributions are the same irrespective of whether the regressors are stationary or (nearly/fractionally) integrated. Two alternative approaches are considered. We first propose an extension of the variable addition method with improved asymptotic power. Second, inference based on instrumental variables may further improve the (local) power of the test. We give primitive conditions under which the suggested procedures are robust.All statistics proposed here are asymptotically standard nor-mal or χ 2 distributed irrespective of the degree of persistence of the regressors. Monte Carlo experiments show that tests based on simple combinations of instru-ments perform quite promising relative to existing tests.