New pre-arrival instructions can avoid abdominal hand placement for chest compressions

Abstract

To investigate if modified pre-arrival instructions using patient's arm and nipple line as landmarks could avoid abdominal hand placements for chest compressions.
Volunteers were randomized to one of two telephone instructions: "Kneel down beside the chest. Place one hand in the centre of the victim's chest and the other on top" (control) or "Lay the patient's arm which is closest to you, straight out from the body. Kneel down by the patient and place one knee on each side of the arm. Find the midpoint between the nipples and place your hands on top of each other" (intervention). Hand placement was conducted on an adult male and documented by laser measurements. Hand placement, quantified as the centre of the compressing hands in the mid-sagittal plane, was compared to the inter-nipple line (INL) for reference and classified as above or below. Fisher's exact test was used for comparison of proportions.
Thirty-six lay people, age range 16--60, were included. None in the intervention group placed their hands in the abdominal region, compared to 5/18 in the control group (p = 0.045). Using INL as a reference, the new instructions resulted in less caudal hand placement, and the difference in mean hand position was 47 mm [95% CI 21,73], p = 0.001.
New pre-arrival instructions where the patient's arm and nipple line were used as landmarks resulted in less caudal hand placements and none in the abdominal region.

Full text

ORIGINAL RESEARCH Open Access
New pre-arrival instructions can avoid abdominal
hand placement for chest compressions
Tonje S Birkenes
1,2*
, Helge Myklebust
2
and Jo Kramer-Johansen
1
Abstract
Objective: To investigate if modified pre-arrival instructions using patient’s arm and nipple line as landmarks could
avoid abdominal hand placements for chest compressions.
Method: Volunteers were randomized to one of two telephone instructions: “Kneel down beside the chest. Place
one hand in the centre of the victim’s chest and the other on top” (control) or “Lay the patient’s arm which is
closest to you, straight out from the body. Kneel down by the patient and place one knee on each side of the arm.
Find the midpoint between the nipples and place your hands on top of each other” (intervention). Hand
placement was conducted on an adult male and documented by laser measurements. Hand placement, quantified
as the centre of the compressing hands in the mid-sagittal plane, was compared to the inter-nipple line (INL) for
reference and classified as above or below. Fisher’s exact test was used for comparison of proportions.
Results: Thirty-six lay people, age range 16–60, were included. None in the intervention group placed their hands in
the abdominal region, compared to 5/18 in the control group (p = 0.045). Using INL as a reference, the new instructions
resulted in less caudal hand placement, and the difference in mean hand position was 47 mm [95% CI 21,73], p = 0.001.
Conclusion: New pre-arrival instructions where the patient’s arm and nipple line were used as landmarks resulted in
less caudal hand placements and none in the abdominal region.
Background
Initiation of bystander CPR doubles the chance of survival
after out-of-hospital cardiac arrest and is probably the most
feasible intervention to improve overall survival in many
communities [1]. CPR pre-arrival instructions resulted in
50% increase in bystander CPR in King County [2,3], and is
recommended by American Heart Association [4].
In the first publication on chest compressions for cardiac
arrest in humans, Kouwenhoven described hand place-
ment as “the heel of one hand […]isplacedonthester-
num just cephalad to the xiphoid” [5]. Subsequent CPR
guidelines have retained the lower half of the sternum as
the target, with different combinations of anatomical land-
marks in the instructions to achieve this.
“Place the heel of the hand on the lower half of sternum”
was used from 1966 to 1974 [6,7]. In 1980 the instructions
changed to: “.. use the lower margin of the victim’sribcage
to find the notch where the ribs meet the sternum” [8].
Guidelines 2000 continued to use the notch, but intro-
duced “the center of the chest between the nipples” as
alternative simplified instructions [9]. In 2005 the in-
struction were simplified to “in the middle of the chest”,
but the American guidelines re commended “in the mid-
dle of the chest, between the nipples” [10]. Both American
and European guidelines have used “in the middle of the
chest” since 2010 [11,12].
These instructions have resulted in a significant rate
of incorrect or too low hand placement on the ste rnum
and e ven in the abdominal region during lay people
manikin CPR [13–18]. When we tested adult lay people
CPR o n a dressed manikin, almost half of the partici-
pants initially compressed in the abdominal region [17].
In this study, we wanted to test a new combination of
anatomical landmarks aimed at avoiding abdominal hand
placements. To make it more realistic, we used a dressed,
adult person playing the role of the patient.
* Correspondence: tonje.birkenes@laerdal.no
1
Institute for Experimental Medical Research, Oslo University Hospital and
University of Oslo, Ulleval, PO Box 4956 Nydalen, N-0426 OSLO, Norway
2
Laerdal Medical AS, Tanke Svilandsgate 30, N-4002 Stavanger, Norway
© 2013 Birkenes et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited.
Birkenes et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2013, 21:47
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Method
Study design
During pilot testing , w e identified sitting astride the
arm and using internipple line (INL) as the best
combination of landmarks to avoid abdominal hand
placement.
We then conducted a randomized study to compare our
new instruction set with ERC’s recommendation. Follow-
ing consent, participants drew from a bowl with closed
envelopes (50/50 control and intervention), without re-
placement. Randomization result was communicated to
dispatcher by researcher on telephone. The study is regis-
tered locally at Oslo University Hospital with project
number 2010/1519.
Participants
We recruited volunteers among employees at the
local Norwegian L abor and W elfare office (NAV )
and from a youth group from The Norwegian Trek-
king A ssociation, excluding participant s with current
or recent duty-to-respond. Written consent was
obtained from all participants. Volunteers from NAV
were offered a free CPR course in return for their
participation.
Test situation
The study was conducted in a well-lit room with two re-
searchers present. The patient was played by a 46 year old
1.87 m tall adult male weighting 93 kg with sternal length
22.5 cm (from xiphosternal junction to jugular notch lying
on the floor, wearing three layers of clothes (underwear,
shirt, and sweater). The scenario was explained to partici-
pant: “This person has a confirmed cardiac arrest and
needs chest compressions. You must follow the instructions
given by the dispatcher on the phone. To save time, you de-
cide not to remove any clothes”. All participants were
handed a phone with an established connection with the
dispatcher and speaker function activated, with the initial
instruction: “Place the phone on the floor in front of you
such that we can hear each other”. The person acting as
dispatcher was located in another facility and pro-
vided instructions according to randomization, with
telephone as the only source of communication.
Two-way communication was possible, and a few
participants a sked the dispatcher to repeat the in-
structions once.
Each instruction set had two parts; to position the res-
cuer next to the victim and placement of the hands on
the chest.
Instructions for the control group (ba sed on ERC re-
commendations):
“Kneel beside the chest. Place the heel of your hand in
the center of the chest with the other on top”
Instructions for the intervention group:
“Lay the patient’s arm which is closest to you, straight out
from the body. Kneel down by the patient and place one
knee on each side of the arm. Find the midpoint between
the nipples and place your hands on top of each other.”
The test was ended when the participant had placed
the hands on the chest. Since we used an adult playing
the role of the patient and not a manikin, the partici-
pants were not asked to perform chest compressions.
Hand placement measurement
Hand placement was measured by using a hard base with
an end plate, measurement tape, laser beam (Black &
Decker LZR6) and a digital camera (Nikon D40x). The
marker was lying with the head against the end plate and
the laser beam direction adjusted to be parallel to his INL.
The hand position was measured using the laser beam at
the upper and lower borders of the compressing hands
and photographed. Hand position offset was quantified as
the distance from the end plate to the center of the
compressing hands in the mid-sagittal plane, compared to
INL and classified as above or below. Negative offset value
indicates hand placement caudal to INL. Hand position
caudal to the xiphosternal junction was classified as ab-
dominal. The laser beam was turned off until the partici-
pants had placed their hands. The researcher was blinded
for the randomization when measuring the hand position
from the photographs. See Figure 1 for test arrangement
and measurement principle.
Statistical analysis
Fisher’s exact test was used for comparison of propor-
tions above and below INL. Un-paired t-test was used
for con tinuous measurements (hand placement offset).
Power analysis
The study was powered based on categ orical pilot data
where we found that only 14% placed their hands on the
internipple line (or cephalad to INL). A power analysis
to detect a change from 14% to 60%, a power (1- β)of
0.8 and a significance level (α) of 0.05, estimated to 17
test persons in each group.
Results
Thirty-eight lay people between 16–60 years old were in-
vited and signed up for the study, which was conducted in
Stavanger (Norway), April 2010.
One control group subject placed the “patient’s” hands
in the center of his chest, instead of her own. Hence no
hand placement data were recorded due to this misunder-
standing of instructions. One other subject declined par-
ticipation on the study day, without giving specific reason.
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No participant ha d any recent obligations a s first-
responders or professional responders to cardiac arrest.
Demographic data of the remaining 37 participants is
described in Table 1.
Using the arm and internipple line as reference, the
new instruction set resulted in less caudal hand place-
ment, and the difference in mean hand position offset
was 47 mm [95% CI 21,73], p = 0.001. None in the inter-
vention group placed their hands in the abdominal re-
gion vs. 5/18 in the control group (p = 0.045) (Table 2
and Figure 2).
Discussion
The instructions of kneeling astride the arm and placing
the hands between the nipples gave less abdominal hand
placement compared to the instruction of placing them
in the center of the chest. One of the reasons is probably
that when sitting astride the arm the distance to the
chest is short with a longer distance to the abdomen.
Hand placement also varied less when using clear ana-
tomical landmarks ( arm a nd nipple line) compared to
the center of the c hest , which we think is more open for
interpreta tio n.
Improving hand placement for chest compressions is
important s ince all the various instructions for hand
placement used in the last decade [12,19,20], have
resulted in poor hand placement [14,15,18,21–23], with
a significant proportion of abdominal hand placement
[16–18].
Table 1 Demography, education and CPR training
background of participants
Participants Control
group
Intervention
group
n=19 n=18
Women 16 13
Age <20 years 5 5
Age ≥20 years 14 13
Completed education
High school 5 5
Occupational school/lower
university grade
76
Higher university grade 6 7
Previous CPR training
Never attended CPR training 3 6
Completed 1–2 CPR courses 14 6
Completed more than 2 courses 2 5
Unknown 0 1
Years since last training:
1-3 years 6 5
4-6 years 3 2
7-9 years 2 2
9+ years 5 2
Unknown 3 7
Figure 1 Test arrangement and measurement principle. Circle (○) indicates laser-ruler intersection for upper and lower border of compressing
hands documented by photo.
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Kneeling astride the arm, hand placement between the
nipples, or both?
Both instruction sets comprises two instructions, and
both instructions in the intervention instruction set are
new. Introducing two new instructions in one interven-
tion raises the question whether it was kneeling astride
the arm or placing the hands between the nipples, or
both, that resulted in less abdominal hand placements.
This study design does not answer this question, as we
decided to test a new instruction set, not just a single
instruction.
Development of these new instructions was an itera-
tive process. In a pre vious simulation study we observed
that many participants knelt down by the lower part of
torso, when given the instructions “kneel down by the
chest”. The majority of these participants also compressed
too low on the chest [17]. To prevent this, we used the
patient’s arm a s landmark to position the rescuer better.
While sitting a stride the arm, the distance to lower half
of sternum and to patient airways is short a nd this allow
rescuers t o remain i n the same position and more easily
alternate between compressions and ventilations with-
out moving sideways.
Neither inter-nipple line nor center of the chest are
clearly visible landmarks with three layers of clothing.
Test subjects had to use their perception of these land-
marks to guide themselves. Yeong reported less variability
using internipple line as landmark compared to center of
the chest, when identifying the location on a photo of
dressed patients [22]. In addition, we observed partici-
pants in our previous simulation study who understood
the center of the chest to be the same as the center of the
torso. We judged that nipple line is a more specific in-
struction. To reduce variability and avoid too low hand
placement, we selected internipple line as landmark for
hand placement.
Table 2 Hand placement relative to internipple line (INL) or over abdomen
Hand placement Reference instructions Intervention instructions
[n = 18] [n = 18]
On/above INL 2 11
Below INL 11 7
Abdominal 5 0
Hand placement Relative to INL Difference
Mean offset* [mm] −46 (±47) 0.8 (±28) 47 [21, 73], p = 0.001
* Minus sign indicates offset value caudal to INL. See “Hand placement measurement” in Methods section for definition.
Results for hand placement. Mean offset is the distance between center of compressing hands and internipple line.
Figure 2 Hand placement in the control and intervention groups. Individual compression point centers are marked by x, the means by a full
line, top and bottom of the sternum and inter-nipple line by interrupted lines.
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“Internipple line is unreliable”
ERC Guidelines 2010 [12] states that internipple line is
unreliable based on studies from Shin [24] and Kusunoki
[25], and therefore lower half of sternum should be used in
guidance for hand placement. Shin reports that internipple
line location varies based on CT scans of adults. Kusunoki
compared hand size (width) with lengths of sternum, and
found that in overall 50% of the cases, the heel of the hand
wouldextendtothexiphoidprocess,butonly3outof506
female patients had an internipple line crossing the xiphoid
process or abdomen. Their validation study also demon-
strated that the combination of female rescuer and male
patient, which is the most likely combination in out of hos-
pital cardiac arrests, [26,27] gave no cases of hand deviation
into epigastrium [25]. Using an average female hand palm
size of 9.8 ± 0.8 cm, as reported by Kusunoki [25], 10/18
participants from our reference group, placed their hands
close to the xiphoid process and would overlap with the
epigastrium, compared to only 3/18 of the intervention
group. Both Kusunoki and Shin reports that the internipple
line crosses the lower half of sternum. This justifies that
“between the nipples” can be used in instructions.
Time to first chest compression and between
compression series
The time from scenario start until hand placement was
not recorded, and it is reasonable to assume that the
delay before the first compression might be longer with
the intervention instructions than in the control group.
Larsen and co-workers estimated a drop in survival by
2.3% per one minute delay to begin CPR [28]. But quality
of CPR seems to matter more: In the studies by Gallagher
[29], Van Hoeyweghen [30] and Wik [31], patients who re-
ceived competent CPR were more than three times more
likely to survive compared to those who received not-
competent CPR. Based on this, it is reasonable to spend
some extra seconds in the beginning to help ensure better
quality CPR by avoiding abdominal compressions.
We did not test the effectiveness of kneeling astride the
arm if a single rescuer performs both chest compressions
and ventilations. This should reduce the need for repo-
sitioning between compression and ventilation attempts
and thereby decrease time between compression series ,
but this needs to be further investigated.
Limitations
The study was performed with only one adult playing
the role of the patient, and in a larger study it would be
beneficial to include several adults of different size and
both genders.
The optimal hand placement for chest compressions is
still unknown. A pilot study by Qvigstad evaluating ETCO
2
as a surrogate marker for cardiac output during CPR on
patients indicates that there is no specific hand placement
that gives optimal cardiac output for all patients [32]. The
purpose of our study was to test if a new set of instructions
would avoid lay people placing their hands in epigastrium.
The translation of the instructions from one language
to another might give semantic differences. To ensure the
instructions are effective, they need to be validated, recog-
nizing that culture and language influence our interpret-
ation of instructions.
We tested instructions for initial hand placement
only. It is unknown whether the participants would have
maintained their hand placement during chest compressions
or if a more cephalad hand placement would cause more
shallow compressions. This should be further investigated.
Conclusion
New pre-arrival instructions where the patient’s arm and
nipple line were used as landmarks resulted in less caudal
hand placements and none in the abdominal region.
Competing interests
Birkenes receive research scholarships provid ed by the Norwegian
Research Council. Birkenes and Myklebust are employees at Laerdal
Medical. Kramer-Johansen receives financial research sup port f rom Laerdal
Medical. The study was sponsored by Laerdal Medical, Stavanger, Norway.
Authors' contributions
All authors participated in the study design. TSB and HM collected the data;
TSB performed the statistical analysis and drafted the manuscript. All authors
have critical reviewed the manuscript, and the study was supervised by JKJ.
All authors read and approved the final manuscript.
Acknowledgements
We would like to thank Petter Westnes for giving telephone instructions
to the participants, Harald Sævareid and Ingunn Anda Haug for support
in cre ating the illustrations, and Joar Eilevstjønn for insightful revision of
the manuscript.
Birkenes receive research scholarships provid ed by the Norwegian
Research Council. Birkenes and Myklebust are employees at Laerdal
Medical. Kramer-Johansen receives financial research sup port f rom Laerdal
Medical. The study was sponsored by Laerdal Medical, Stavanger, Norway.
Received: 19 March 2013 Accepted: 16 June 2013
Published: 22 June 2013
References
1. Holmberg M, Holmberg S, Herlitz J: Effect of bystander cardiopulmonary
resuscitation in out-of-hospital cardiac arrest patients in sweden.
Resuscitation 2000, 47(1):59–70.
2. Culley LL, Clark JJ, Eisenberg MS, Larsen MP: Dispatcher-assisted telephone
CPR: Common delays and time standards for delivery. Ann Emerg Med
1991, 20(4):362–366.
3. Rea TD, Eisenberg MS, Culley LL, Becker L: Dispatcher-assisted
cardiopulmonary resuscitation and survival in cardiac arrest. Circulation
2001, 104(21):2513–2516.
4. Lerner EB, Rea TD, Bobrow BJ, et al: Emergency medical service dispatch
cardiopulmonary resuscitation prearrival instructions to improve survival
from out-of-hospital cardiac arrest: a scientific statement from the
american heart association. Circulation 2012, 125(4):648–655.
5. Kouwenhoven WB, Jude JR, Knickerbocker GG: Closed-chest cardiac
massage. JAMA 1960, 173:1064–1067.
6. National Academy of Sciences-National Research Council: Cardiopulmonary
resuscitation - statement by ad hoc committee of national academy of
sciences. JAMA 1966, 198:138–145.
7. American Heart Association: Standards for cardiopulmonary resuscitation
(CPR) and emergency cardiac care (ECC). JAMA 1974, 227(7):833.
Birkenes et al. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2013, 21:47 Page 5 of 6
http://www.sjtrem.com/content/21/1/47

8. American Heart Association: Standards and guidelines for
cardiopulmonary resuscitation (CPR) and emergency cardiac care (ECC).
JAMA 1980, 244(5):453–509.
9. European Resuscitation Council: International guidelines 2000 for CPR and
ECC - A consensus on science. Resuscitation 2000, 46:1–448.
10. ECC Committee, Subcommittees and Task Forces of the American Heart
Association: 2005 american heart association guidelines for
cardiopulmonary resuscitation and emergency cardiovascular care.
Circulation 2005, 112(24 Suppl):IV1–203.
11. American Heart Association: 2010 american heart association guidelines
for cardiopulmonary resuscitation and emergency cardiovascular care
science. Circulation 2010, 122(18 Suppl 3):S640–S946.
12. European Resuscitation Council: European resuscitation council guidelines
for resuscitation 2010. Resuscitation 2010, 81(10)):1219–1452.
13. Mortensen RB, Hoyer CB, Pedersen MK, Brindley PG, Nielsen JC: Comparison
of the quality of chest compressions on a dressed versus an undressed
manikin: A controlled, randomised, cross-over simulation study. Scand J
Trauma Resusc Emerg Med 2010, 18:16.
14. Handley AJ: Teaching hand placement for chest compression-a simpler
technique. Resuscitation 2002, 53(1):29–36.
15. Einspruch EL, Lynch B, Aufderheide TP, Nichol G, Becker L: Retention of CPR
skills learned in a traditional AHA heartsaver course versus 30-min video
self-training: A controlled randomized study. Resuscitation 2007,
74(3):476–486.
16. Nielsen AM, Henriksen MJ, Isbye DL, Lippert FK, Rasmussen LS: Acquisition
and retention of basic life support skills in an untrained population
using a personal resuscitation manikin and video self-instruction (VSI).
Resuscitation 2010, 81(9):1156–1160.
17. Birkenes TS, Myklebust H, Neset A, Olasveengen TM, Kramer-Johansen J:
Video analysis of dispatcher-rescuer teamwork-effects on CPR technique
and performance. Resuscitation 2012, 83(4):494–499.
18. Kellermann AL, Hackman BB, Somes G: Dispatcher-assisted
cardiopulmonary resuscitation. validation of efficacy. Circulation 1989,
80(5):1231–1239.
19. American Heart Association: Guidelines 2000 for cardiopulmonary
resuscitation and emergency cardiovascular care. Circulation 2000,
102(8):I1–I370.
20. European Resuscitation Council: European resuscitation council guidelines
for resuscitation 2005. Resuscitation 2005, 67(Suppl 1):S1–S189.
21. Woollar d M , Smith A, Whitfield R, et al: To blow or not to blow: a
randomised controlled trial of compression-only and standard
telephone CPR instructions in simulated car diac arres t. Resuscitation
2003, 59(1):123–131.
22. Yeung J, Butler T, Digby JW, et al: Basic life support prov iders’
assessment of centre of t he chest and inter-nipple line for hand
position and their underl ying anatomical structures. Resuscitation 2011,
82(2):190–194 .
23. Cheung S, Deakin CD, Hsu R, Petley GW, Clewlow F: A prospective
manikin-based observational study of telephone-directed
cardiopulmonary resuscitation. Resuscitation 2007, 72(3):425–435.
24. Shin J, Rhee JE, Kim K: Is the inter-nipple line the correct hand position
for effective chest compression in adult cardiopulmonary resuscitation?
Resuscitation 2007, 75(2):305–310.
25. Kusunoki S, Tanigawa K, Kondo T, Kawamoto M, Yuge O: Safety of the
inter-nipple line hand position landmark for chest compression.
Resuscitation 2009, 80(10):1175–1180.
26. Herlitz J: Nationellt register för hjärtstopp - årsrapport 2010. Göteborg,
Sweden: Flisa & HLR-rådet; 2010.
27. Swor R, Khan I, Domeier R, Honeycutt L, Chu K, Compton S: CPR training
and CPR performance: Do CPR-trained bystanders perform CPR? Acad
Emerg Med 2006, 13(6):596–601.
28. Larsen MP, Eisenberg MS, Cummins RO, Hallstrom AP: Predicting survival
from out-of-hospital cardiac arrest: A graphic model. Ann Emerg Med
1993, 22(11):1652–1658.
29. Gallagher EJ, Lombardi G, Gennis P: Effectiveness of bystander
cardiopulmonary resuscitation and survival following out-of-hospital
cardiac arrest. JAMA 1995, 274(24):1922
–1925.
30. Van Hoeyweghen RJ, Bossaert LL, Mullie A, et al: Quality and efficiency of
bystander CPR. belgian cerebral resuscitation study group. Resuscitation
1993, 26(1):47–52.
31. Wik L, Steen PA, Bircher NG: Quality of bystander cardiopulmonary
resuscitation influences outcome after prehospital cardiac arrest.
Resuscitation 1994, 28(3):195–203.
32. Qvigstad E, Kramer-Johansen J, Tomte O, et al: Clinical pilot study of different
hand positions during manual chest compressions monitored with
capnography. Resuscitation 2013. doi:10.1016/j.resuscitation.2013.03.010
doi:10.1186/1757-7241-21-47
Cite this article as: Birkenes et al.: New pre-arrival instructions can avoid
abdominal hand placement for chest compr essions. Scandinavian Journal
of Trauma, Resuscitation and Emergency Medicine 2013 21:47.
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