This study presents a descriptive content analysis of the research trends of postgraduate theses conducted in the field of science
education on biotechnological concepts in Turkey between 2000-2020. In line with the aim of the study, 65 postgraduate theses in total
were examined by searching the database of the Council of Higher Education (CoHE) National Thesis Center. In this study using document
analysis, one of the qualitative research designs, theses were analyzed according to years, universities, study subjects, concepts, methods, data collection tools, sampling, and sample size. The results showed that theses were predominantly master's theses, postgraduate theses conducted in the field of science education on biotechnological concepts were carried out in a total of 27 universities, and theses were mainly conducted at Gazi University, Inonu University, and Bolu Abant Izzet Baysal University. Regarding the subject distribution, it was seen that theses were mainly written on the attitudes, perceptions, and interests of middle school, high school, and university students and
teachers concerning biotechnology and were teaching- and learning-oriented. Furthermore, it was concluded that quantitative approaches were mostly used in the examined theses, and experimental designs among quantitative research methods were preferred more than non-experimental designs. As data collection tools, mostly skill, attitude, perception, personality, etc. tests, achievement tests, Likert-type
questionnaires, and semi-structured interviews were used, and it was observed that the most preferred sample group was university and
high school students and the sample size was mostly between 101-300 and 31-100. Based on the study results, it can be suggested that researchers conduct more studies on biotechnology-related subjects using different samples and scales.