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Comparison of smoking habits of Blacks and Whites in a case-control study

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Abstract and Figures

Information from Blacks and Whites interviewed in a case-control study of tobacco-related diseases was analyzed to identify explanatory factors for racial differences in smoking habits. Blacks were three times more likely to be light vs heavy smokers. This association did not differ according to such variables as cigarette preference, degree of inhalation, or quitting. The association of race and light smoking was present in both current and ex-smokers. Sociodemographic or smoking-related characteristics do not appear to explain racial differences in smoking habits. Future studies should focus on cultural factors influencing smoking behavior.
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Comparison
of
Smoking
Habits
of
Blacks
and
Whites
in
a
Case-Control
Study
Geoffry
C.
Kabat,
PhD,
Alfredo
Morabia,
MD,
PhD,
and
Emst
L.
Wynder,
MD
Intrducion
Incidence
rates
of
tobacco-related
cancers,
such
as
cancers
of
the
lung,
esophagus,
larynx,
and
oral
cavity,
are
higher
in
Black
than
in
White
Americans.1
In
addition,
Blacks
are
more
often
current
smokers
but,
on
average,
smoke
fewer
cigarettes
per
day
than
Whites.2-8
Blacks
also
tend
to
smoke
higher
tar,
higher
nic-
otine,
and
more
mentholated
cigarettes
than
Whites.5'9'10
Understanding
the
causes
of
racial
differences
in
smoking
habits
has
major
public
health
implications
since
it
deter-
mines
the
best
strategy
for
smoking
ces-
sation.
Racial
differences
are
apparently
not
attnbutable
to
socioeconomic
factors2
but,
to
our
knowledge,
the
role
of
smok-
ing-related
factors
such
as
tar
level,
men-
tholation,
inhalation,
degree
of
habitua-
tion,
butt
length,
and
quitting
has
not
been
examined
heretofore.
Metwds
Data
presented
here
derive
from
a
previously
descnibed
hospital-based
case-
control
study
of
tobacco-related
can-
cers.11
Briefly,
case
patients
with
cancers
of
the
lung,
larynx,
oral
cavity,
esopha-
gus,
bladder,
pancreas,
and
kidney
and
first
occurrences
of
nonfatal
myocardial
infarction
were
interviewed
in
28
collab-
orating
hospitals
in
eight
US
cities.
At
least
one
control
patient
with
a
condition
not
known
to
be
related
to
smoking
or
alcohol
was
interviewed
within
2
months
following
the
case
patient's
interview.
Control
patients
were
matched
to
case
pa-
tients
on
sex,
age
(+/-
5
years),
race,
and
hospital.
A
total
of 23
011
case
and
control
pa-
tients,
of
whom
9%
were
Black,
were
in-
terviewed
between
1980
and
1990.
After
removal
of
exclusively
pipe
and/or
cigar
smokers
(n
=
903),
5301
never
smokers
(8%
Black),
9252
current
smokers
(11%
Black),
and
7555
former
smokers
(6%
Black)
remained
for
analysis.
The
distribution
of
diagnoses
was
similar
between
Black
and
White
case
pa-
tients.
The
most
common
case
diagnoses
in
men
were
lung
cancer
(37%
of
White
and
Black
case
patients),
myocardial
in-
farction
(21%
of
Whites,
18%
of
Blacks),
oral
cancer
(13%,
17%),
and
larynx
cancer
(7%,
8%).
Among
control
patients,
Blacks
had
a
smaller
proportion
of
cancers
than
Whites,
because
Blacks
are
underrepre-
sented
in
collaborating
hospitals
with
al-
most
exclusively
cancer
patients.
The
study
questionnaire
contained
detailed
items
on
smoking
history,
includ-
ing
age
at
initiation;
tobacco
products
(cig-
arettes,
cigars,
pipes,
chewing
tobacco,
snuff);
up
to
four
cigarette
brands,
speci-
fying
whether
filter
or
mentholated;
years
of
smoking
each
brand;
and,
for
ex-smok-
ers,
the
number
of
years
since
quitting.
Information
was
also
available
on
inhala-
tion
(not
at
all,
slightly,
moderately,
deep-
ly),
how
much
of
the
cigarette
the
subject
usually
smoked,
and
how
long
after
wak-
ing
the
subject
generally
smoked
his
or
her
first
cigarette
of
the
day
(0
through
15
min-
utes,
16
through
30
minutes,
31
through
59
minutes,
60+
minutes).
A
smoker
was
defined
as
one
who
had
smoked
at
least
one
cigarette
per
day
for
at
least
1
year.
A
smoker
who
had
smoked
within
a
year
of
diagnosis
was
a
current
smoker,
otherwise
an
ex-smoker.
A
"heavy"
smoker
was
defined
as
a
smoker
of
more
than
a
pack
per
day
(2
21
ciga-
rettes
per
day).
Tar
level
was
categorized
into
low,
moderate,
and
high
tar
(<
10,
10
through
14.9,
2
15
mg/cigarette).
Mentho-
lation
was
categorized
into
nonmenthol
only
(those
who
had
never
smoked
a
men-
tholated
brand
for
at
least
1
year),
menthol
At
the
time
of
this
study,
all
authors
were
with
the
American
Health
Foundation,
New
York.
Alffedo
Morabia
is
now
with
the
Clinical
Epi-
demiology
Unit
of
the
University
Cantonal
Hospital,
Geneva,
Switzerland.
Requests
for
reprints
should
be
sent
to
Geoffrey
C.
Kabat,
PhD,
Division
of
Epidemi-
ology,
American
Health
Foundation,
320
East
43rd
Street,
New
York,
NY
10017.
This
paper
was
submitted
to
the
journal
April
5,
1991,
and
accepted
with
revisions
July
9,
1991.
American
Journal
of
Public
Health
1483
Public
Health
Briefs
adjust
for
confoundingvariables
and
to
as-
sess
multiplicative
interaction.
Results
The
breakdown
of
the
total
study
population
by
case-control
status,
sex,
and
race
is
displayed
in
Table
1.
As
in
national
surveys,
the
prevalence
of
cur-
rent
smoking
was
higher
in
Blacks.
Among
current
smokers
in
the
control
group,
Blacks
smoked
fewer
cigarettes
per
day,
tended
to
smoke
higher
tar
and
mentholated
cigarettes,
and
tended
to
have
smoked
for
fewer
years
compared
with
Whites
(Table
2).
Black
men
and
women
were
much
more
alike
in
terms
of
amount
smoked
than
were
White
men
and
women
(Table
2).
Among
control
patients
(not
shown
in
Table
2),
Black
men
were
5.0
(95%
con-
fidence
interval
[CI]
=
3.3-7.1)
times
more
likely,
and
Black
women
were
2.5
(95%
CI
=
1.4-6.7)
times
more
likely,
to
be
light
smokers.
For
case
patients,
the
corresponding
ORs
and
95%
CIs
were
3.0
(2.6-4.2)
for
men
and
3.0
(2.0-4.4)
for
women.
These
associations
persisted
across
strata
of
age,
education,
marital
status,
Quetelet's
Index,
menthol
use,
tar
level,
inhalation,
duration
of
smoking,
butt
length,
and
timing
of
first
cigarette.
As
shown
in
Table
3,
among
male
control
patients
the
association
of
race
with
light
smoking
was
greater
in
current
smokers
(OR
=
5.0;
95%
CI
=
3.4-7.5)
than
in
ex-smokers
(OR
=
2.5;
95%
CI
=
1.6-3.7).
The
interaction
was
statis-
tically
significant
(P
=
.01)
and
was
of
similar
magnitude
within
strata
of
age,
Quetelet
Index,
tar
level,
inhalation,
and
alcohol.
Differences
between
current
and
ex-smokers
were
even
stronger
among
more
educated
subjects
and
among
smok-
ers
of
mentholated
cigarettes.
In
these
two
subgroups,
among
current
smokers
Blacks
were
about
7
times
more
likely
than
Whites
to
be
light
smokers,
but
among
ex-smokers
Blacks
were
only
about
1.5
times
more
likely
to
be
light
smokers.
No
interaction
among
smoking
status,
level
of
smoking,
and
race
was
seen
in
female
control
patients (not
shown
in
Table
3).
1
through
14
years,
or
menthol
15
years
or
more
based
on
lifetime
smoking
history.
We
present
Black-White
compari-
sons
in
case
and
control
patients
to
dem-
onstrate
that
the
pattern
of
differences
is
not
an
artifact
of
the
study
design.
We
also
determined
whether
differences
in
smok-
ing
between
the
two
races
were
present
in
both
current
and
ex-smokers.
We
com-
puted
the
odds
ratio
(OR)
of
being
a
light
vs
a
heavy
smoker
related
to
race
(Black
vs
White)
and
used
logistic
regression
to
Diwuion
In
the
present
study,
more
Blacks
smoked;
however,
among
smokers,
Blacks
smoked
fewer
cigarettes
per
day
than
Whites.
This
pattern
was
constant
across
subgroups
defined
by
sex,
case-
control
status,
sociodemographic
factors,
1484
American
Journal
of
Public
Health
November
1991,
Vol.
81,
No.
11
Public
Health
Brie
life-style
factors,
and
smoking
behaviors,
and
is
consistent
with
US
survey
data.24,6
Novotny
et
al.
reported
that
Blacks
were
less
likely
than
Whites
to
be
heavy
smokers,
after
adjustment
for
employ-
ment
status,
blue/white
collar
status,
ed-
ucation,
and
poverty
level.2
Our
results
are
consistent
with
the
latter
findings
but,
in
addition,
suggest
that
the
larger
propor-
tion
of
light
smokers
among
Black
current
smokers
is
not
explained
by
differences
in
smoking-related
factors.
The
agreement
of
our
results
with
National
Health
Interview
Survey
data
makes
selection
or
recall
bias
of
hospital
patients
an
unlikely
explanation.4.12
How-
ever,
purchasing
power
could
account
for
the
racial
difference
in
level
of
smoking.
Although,
in
the
present
study,
Black-
White
differences
persisted
within
strata
of
educational
level,
education
may
be
a
poor
indicator
of
socioeconomic
status
when
comparing
Blacks
and
Whites.
Another
explanation
is
that
since
the
proportion
of
quitters
is
higher
among
Whites
and
since
light
smokers
are
more
likely
to
quit,13
this
Could
lead
to
an
over-
representation
of
heavy
smokers
among
White
current
smokers.
Indeed,
there
is
such
a
phenomenon,
but
it
does
not
com-
pletely
explain
the
observed
association
of
race
and
smoking
habits
since
Black-
White
differences
persist,
even
though
at-
tenuated,
among
ex-smokers
(Table
3).
It
is
also
possible
that
Blacks
are
less
suscepti-
ble
to
becoming
habituated
to
smoking
since
they
inhale
less
(Table
2)
and
have
higher
mean
cotinine
levels
compared
with
Whites
for
a
similar
level
of
smoking.14.15
In
conclusion,
smoking-related
fac-
tors
do
not
seem
to
explain
racial
differ-
ences
in
smoking
habits.
Thus,
effective
preventive
strategies
aiming
at
smoking
cessation
may
require
a
better
under-
standing
of
cultural
factors
that
affect
smoking,
such
as
the
timing
of
the
most
"important"
cigarettes,
whether
smoking
is
engaged
in
mainly
in
the
company
of
others,
reason
for
smoking,
reason
for
smoking
mentholated
cigarettes
(where
applicable),
and
degree
of
satisfaction
from
smoking.
O
Acknowledgments
Portions
of
the
material
contained
in
this
paper
were
presented
at
the
12th
scientific
meeting
of
the
International
Epidemiological
Association,
Los
Angeles,
August
9,
1990.
This
research
was
supported
by
National
Cancer
Institute
Contract
N01-CP.05684
and
Grant
CA-32617.
We
would
like
to
acknowledge
the
valu-
able
contributions
of
the
following
cooperating
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institutions
and
individuals:
Memorial
Hospital
(New
York,
NY),
Dr.
David
Schottenfeld
and
Dr.
Nael
Martini;
Manhattan
Veterans
Hospi-
tal
(New
York,
NY),
Dr.
Norton
Spritz;
Long
Island
Jewish
Hillside
Medical
Center
(New
York,
NY),
Dr.
Arthur
Sawitsky,
University
of
Alabama
Hospital
(Birmingham,
Ala),
Dr.
William
Bridgers;
Birmingham
Veterans
Hos-
pital
(Bimingham,
Ala),
Dr.
Herman
L.
Leh-
man;
Loyola
University
Hospital
(Chicago,
IIl),
Dr.
Walter
S.
Wood;
Hines
Veterans
Hospital
(Chicago,
Ill),
Dr.
John
Sharp;
Henry
Ford
Hospital
(Detroit,
Mich),
Robert
M.
O'Bryan,
MD,
and
Christine
Johnson,
PhD;
Hospital
of
the
University
of
Pennsylaa
(Philadelphia,
Pa),
Dr.
Paul
Stolley;
Jefferson
Medical
College
and
Thomas
Jefferson
University
Hospital
(Philadelphia,
Pa),
Dr.
J.
E.
Colberg;
Alleghe-
ny
General
Hospital
(Pittsburgh,
Pa),
Dr.
Stan-
ley
A.
Briller;
University
of
Pittsburgh
Eye
and
Ear
Hospital
(Pittsburgh,
Pa),
Dr.
Lewis
H.
Kuller;
Pittsburgh
Veterans
Hospital
(Pitts-
burgh,
Pa),
Dr.
Eugene
N.
Meyers;
Moffitt
Hospital
and
University
of
California
at
San
Francisco
and
County
Hospital
(San
Fran-
cisco,
Calif),
Dr.
Nicholas
Petrakds;
St.
Luke's
Hospital
(San
Francisco,
Calf),
Dr.
Richard
A.
Bohannan;
Georgia
Baptist
(Atlanta,
Ga),
Dr.
A.
H.
Letton;
and
Emory
University
Clinic
(Atlanta,
Ga),
Dr.
K.
Mansour.
We
would
also
like
to
thank
Dr.
Ken
Resnicow
for
thoughtful
comments
on
the
manuscript,
Pao
Huan
Chung
for
programming
assistance,
and
Laurie
Marmelstein
for
preparation
of
the
manuscript.
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1988.
15.
WagenknechtLE,
Cutter
GR,
HaleyNJ,
et
al.
Racial
differences
in
serum
cotinine
lev-
els
among
smokers
in
the
Coronary
Artery
Risk
Development
in
(Young)
Adults
study.
Am
JPublic
Health.
1990;80:1053-
1056.
A
5-Year
Follow-up
Study
of
117
Battered
Women
Bo
Bergman,
MD,
DrMed
Sci,
and
Bo
Bnsmar,
MD,
DrMed
Sci
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Intdudion
During
the
last
few
decades,
with
more
and
more
attention
being
given
to
the
problem
of
wife
battering,
various
in-
tervention
programs
aimed
at
stopping
the
battering
or
otherwise
helping
or
support-
ing
battered
wives
have
been
tried.1-3
However,
conclusive
information
con-
cerning
the
effect
of
different
intervention
programs
is
sorely
lacking.
In
this
study
the
use
of
medical
care
will
be
used
as
an
indicator
of
the
general
life
strain,
including
battering,
under
which
battered
women
live.
The
aim
of
the
study
was
to
investigate
the
use
of
somatic
and
psychiatric
hospital
care
by
battered
women
and
to
use
these
data
as
a
model
to
evaluate
the
effectiveness
of
a
wife
battering
intervention
program
in
a
medical
setting.
Subjects
and
Method
From
November
1983
to
June
1984,
there
was
an
emergency
room
project
at
the
Huddinge
Hospital,
Huddinge,
Swe-
den,
that
attempted
to
identify
and
sup-
port
battered
women
seeking
hospital
care.
All
women
in
the
emergency
room
who
reported
injuries
resulting
from
bat-
tering
were
offered
admission
to
the
hos-
pital
even
if
the
injuries
did
not
warrant
it
per
se.
The
women
were
given
supportive
counseling
by
a
social
worker
and,
if
nec-
essary,
they
talked
to
a
psychiatrist.
They
were
also
offered
continued
supportive
counseling
by
the
social
worker
after
re-
turning
home,
and,
on
these
occasions,
they
were
provided
an
opportunity
to
con-
tact
social
services,
lawyers,
and
other
sources
of
help.
During
the
8-month
period
in
ques-
tion,
a
total
of 117
battered
women
sought
help
in
the
emergency
room.
Fifty-eight
agreed
to
enter
the
treatment
program,
and
59
went
home
after
routine
care.
The
batterer
was
the
woman's
husband,
co-
habitant,
or
steady
partner
(65%);
her
ex-
husband
or
ex-cohabitant
(19%);
or
a
close
male
relative
(16%).
The
mean
age
at
the
time
of
the
battering
was
33
+
2
years
(range:
16-75).
The
battered
women
were
compared
with
a
control
group
that
was
selected
from
the
population
register
and
matched
with
the
group
of
117
battered
women
for
age
and
geographic
area
in
Stockholm.
The
battered
women
and
the
control
subjects
were
studied
regarding
consump-
tion
of
somatic
and
psychiatric
hospital
care
during
the
period
from
10
years
be-
fore
to
5
years
after
the
battering.
These
data
were
obtained
from
the
Stockholm
County
Council's
computer
files,
supple-
Bo
Bergman
is
with
the
Department
of
Psychi-
atry
and
Bo
Brismar
is
with
the
Department
of
Surgery
of
Huddinge
Hospital,
Karolinska
In-
stitute,
Huddinge,
Sweden.
Requests
for
reprints
should
be
sent
to
Dr.
Bo
Bergman,
Department
of
Psychiatry,
Karo-
linska
Institute/Huddinge
Hospital,
S-141
86
Huddinge,
Sweden.
This
paper
was
submitted
to
the
journal
May
5,
1990,
and
accepted
with
revisions
April
4,
1991.
November
1991,
Vol.
81,
No.
11
... These findings might indicate underlying genetic differences in the development of smoking behaviors in EAs and AAs. AAs tend to start smoking later in life [93][94][95][96] and have a lower lifetime prevalence of ND compared to EAs. 97 Additionally, AAs report higher cravings and more pleasurable sensations after smoking, 96,98 lower rates of regular smoking, [94][95][96][97][99][100][101][102][103] higher nicotine intake per cigarette, 104 and slower metabolism rates of nicotine 103-107 compared to EAs. Finally, EAs have higher smoking cessation rates than AAs. ...
Article
Introduction: Cigarette smoking is a physiologically harmful habit. Nicotinic acetylcholine receptors (nAChRs) are bound by nicotine and upregulated in response to chronic exposure to nicotine. It is known that upregulation of these receptors is not due to a change in mRNA of these genes, however, more precise details on the process are still uncertain, with several plausible hypotheses describing how nAChRs are upregulated. We have manually curated a set of genes believed to play a role in nicotine-induced nAChR upregulation. Here, we test the hypothesis that these genes are associated with and contribute risk for nicotine dependence (ND) and the number of cigarettes smoked per day (CPD). Methods: Studies with genotypic data on European and African Americans (EAs and AAs, respectively) were collected and a gene-based test was run to test for an association between each gene and ND and CPD. Results: Although several novel genes were associated with CPD and ND at P < 0.05 in EAs and AAs, these associations did not survive correction for multiple testing. Previous associations between CHRNA3, CHRNA5, CHRNB4 and CPD in EAs were replicated. Conclusions: Our hypothesis-driven approach avoided many of the limitations inherent in pathway analyses and provided nominal evidence for association between cholinergic-related genes and nicotine behaviors. Implications: We evaluated the evidence for association between a manually curated set of genes and nicotine behaviors in European and African Americans. Although no genes were associated after multiple testing correction, this study has several strengths: by manually curating a set of genes we circumvented the limitations inherent in many pathway analyses and tested several genes that had not yet been examined in a human genetic study; gene-based tests are a useful way to test for association with a set of genes; and these genes were collected based on literature review and conversations with experts, highlighting the importance of scientific collaboration.
... Response to pharmacotherapy for smoking cessation may differ in AAs compared with other racial/ethnic groups for a range of reasons, including racial variation in smoking patterns and socioeconomic status, pharmacokinetic and pharmacodynamics factors, and other biological and genetic factors. 7,8 Few studies examining smoking cessation pharmacotherapies have enrolled sufficient numbers of AAs to make meaningful direct comparisons of outcomes relative to EAs. However, several recent studies in other therapeutic areas have highlighted differential or reduced treatment response among AA subgroups, including in depression and heart failure. ...
Article
To determine whether there were differential quit rates between African Americans (AA) and European Americans with the experimental treatment naltrexone, and examine the role of genetic ancestry on these outcomes among AAs. Data from a previous randomized trial of 315 smokers to naltrexone versus placebo were reanalyzed using West African (WA) genetic ancestry to define subpopulations. Logistic regression models were used to estimate treatment effects on early and end of treatment quit rates, by race and WA ancestry. Among European Americans (n=136), naltrexone significantly increased quit rates at 4 weeks (62 vs. 43%, P=0.03) with directional, but not statistically significant effects at 12 weeks (30 vs. 18%, P=0.12). In contrast, among the AAs (n=95), quit rates did not differ between naltrexone and placebo groups at either interval (4 weeks: 43 vs. 32%, P=0.27; 12 weeks: 22 vs. 18%, P=0.60). A median split was conducted in AAs for WA ancestry. Among AAs with low WA ancestry, quit rates were significantly higher with naltrexone compared with placebo (60 vs. 27%, P=0.03). There was no advantage in quit rates with naltrexone for the high WA ancestry group. Naltrexone efficacy for smoking cessation varies across AA individuals with different levels of WA ancestry. These results suggest that genetic background may partially explain racial differences in drug response.
Article
Introduction: Large racial disparities exist in the prevention and treatment of smoking-related diseases, and minoritized populations carry a heavier burden of smoking-related morbidity and mortality. To date, most studies investigating smoking-related illnesses have been conducted in samples in which the majority, or totality, self-identified as White or Caucasian. While Black individuals who smoke tend to have a lower rate of nicotine clearance, in part due to the use of mentholated cigarettes, less is known about how slower clearance affects their acute subjective and physiologic responses in response to either overnight abstinence or subsequent nicotine administration. This study aimed to investigate differences between the experiences of Black and White individuals who smoke across these outcomes after a period of short-term abstinence and after IV nicotine infusion. Methods: The study included 206 smokers (N = 103 Black, N = 103 White, by self-report). The study investigated self-report, physiological, and biochemical smoking-related outcomes following confirmed overnight abstinence followed by IV nicotine infusion. The outcome measures were separately analyzed with repeated-measures mixed-models. Results: Black individuals had lower rates of nicotine clearance and were more likely to smoke mentholated cigarettes than White individuals. Despite these differences, no differences in withdrawal, cravings, or physiological outcomes were observed between the two groups. There were some trends toward differences in subjective experiences, in that an interaction with trend level significance between race and dose was observed for negative subjective drug effects, with White smokers trending towards endorsing higher levels of negative affect after abstinence and nicotine infusion. We also observed that Black individuals trended towards experiencing more negative drug effects in response to initial nicotine delivery than to saline, whereas White individuals had no differences in negative drug effects across saline or nicotine doses. Conclusions: Despite slower nicotine clearance, Black participants exhibited withdrawal and urges to smoke as severe as White participants, and did not have blunted physiological responses to overnight abstinence or administration of nicotine, which were contrary to our hypotheses. Our findings suggest minimal differences across races in the acute pharmacologic effects of nicotine. We observed trend-level differences in subjective and affective responses to nicotine. Greater insight into these differences may lead to improved prevention and treatment strategies for smoking-related illnesses for Black individuals who smoke.
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Full-text available
Research on the cigarette-smoking patterns of biracial adolescents and young adults is severely limited. In this study, we tested the intermediate biracial substance-use hypothesis, which suggests that the prevalence of substance use among biracial individuals falls intermediate to their monoracial counterparts. We examined cigarette-smoking trajectories of a de-aggregated sample of biracial Black adolescents and young adults. We used longitudinal data from the National Longitudinal Study of Adolescent and Adult Health (Add Health; Harris et al., 2009). Our sample (N = 9,421) included 4 monoracial groups (Black, White, Hispanic, and American Indian [AI]) and 3 biracial groups (Black–AI, Black–Hispanic, and Black–White). Study hypotheses were tested using latent growth-curve modeling. We found some support for the intermediate biracial substance-use hypothesis for 2 of 3 biracial groups (Black–American Indian, Black–Hispanic) and 2 of 4 cigarette-use outcomes (lifetime cigarette use, number of cigarettes smoked during past month for regular smokers). The cigarette-use trajectories of biracial Blacks were significantly different from only 1 corresponding monoracial group. Black–AIs and Black Hispanics engage in lifetime cigarette use at comparable rates to monoracial Blacks. Black–Hispanic regular smokers’ rate of cigarette smoking is comparable to the higher rates of Hispanics and not to the lower rates of Blacks. Knowledge of the origins, developmental course, and consequences of tobacco use among the biracial population may lead to effective intervention programs and policies for this group.
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Cancer is the most fatal and lethal disease for our society and the patients suffering from this are increasing continuously. There are many reasons of increasing number of cancer patients. Among others, the modernization of our society is contributing a lot towards cancer genesis. Therefore, the present article high lights the role of modernization for increasing number of cancer patients. Attempts have been made to describe various factors (modernizations) responsible for producing different types of cancers in human beings. Besides, efforts were also made to suggest the preventive and curable measures to control this lethal ailment. Among various suggestions, mass awareness is the most important tool to get rid of this curse serious disease.
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Context African Americans disproportionately experience greater smoking attributable morbidity and mortality. Few clinical trials for smoking cessation in African Americans have been conducted, despite a different profile of both smoking and quitting patterns.Objective To compare a sustained-release form of bupropion hydrochloride (bupropion SR) with placebo for smoking cessation among African Americans.Design, Setting, and Participants Randomized, double-blind, placebo-controlled trial conducted from February 11, 1999, to December 8, 2000, of 600 African American adults treated at a community-based health care center. Volunteers, who smoked 10 or more cigarettes per day were recruited by targeted media and health care professionals.Intervention Participants were randomly assigned to receive 150 mg of bupropion SR (n = 300) or placebo (n = 300) twice daily for 7 weeks. Brief motivational counseling was provided in-person at baseline, quit day, weeks 1 and 3, end of treatment (week 6), and by telephone at day 3 and weeks 5 and 7.Main Outcome Measures Biochemically confirmed 7-day point prevalence abstinence at weeks 6 and 26 following quit day.Results Using intention-to-treat procedures, confirmed abstinence rates at the end of 7 weeks of treatment were 36.0% in the bupropion SR group and 19.0% in the placebo group (17.0 percentage point difference; 95% confidence interval, 9.7-24.4; P<.001). At 26 weeks the quit rates were 21.0% in the treatment and 13.7% in the placebo groups (7.3 percentage point difference; 95% confidence interval, 1.0-13.7; P = .02). Those taking bupropion SR experienced a greater mean reduction in depression symptoms at week 6 (2.96 [9.45] vs 1.13 [8.84]) than those taking placebo, and after controlling for continuous abstinence, those taking bupropion SR also gained less weight than those taking placebo.Conclusions Bupropion SR was effective for smoking cessation among African Americans and may be useful in reducing the health disparities associated with smoking.
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African Americans are disproportionately exposed to and targeted by prosmoking advertisements, particularly menthol cigarette ads. Though African Americans begin smoking later than whites, they are less likely to quit smoking than whites.PurposeJump to sectionPurposeMethodsResultsDiscussion and Translation to Health Education PracticeBackgroundPurposeMethodsResultsDiscussion and Translation to Health Education PracticeConclusionsThis study was designed to explore African American smoking cessation attitudes, behaviors, and resources to gain insights on how to enhance the appeal of smoking cessation interventions in African American communities.MethodsJump to sectionPurposeMethodsResultsDiscussion and Translation to Health Education PracticeBackgroundPurposeMethodsResultsDiscussion and Translation to Health Education PracticeConclusionsTen focus groups were conducted with urban, suburban, and rural African American adult smokers and ex-smokers in Maryland who also completed brief questionnaires.ResultsJump to sectionPurposeMethodsResultsDiscussion and Translation to Health Education PracticeBackgroundPurposeMethodsResultsDiscussion and Translation to Health Education PracticeConclusionsAlthough knowledge of negative health effects of smoking and motivation for smoking cessation were high, participants lacked confidence in their ability to quit successfully and were poorly informed about resources and programs for smoking cessation.Discussion and Translation to Health Education PracticeJump to sectionPurposeMethodsResultsDiscussion and Translation to Health Education PracticeBackground PurposeMethods ResultsDiscussion and Translation to Health Education PracticeConclusions Findings from this study suggest that cultural tailoring, neighborhood focus, and strong marketing may enhance the appeal of smoking cessation programs to African American smokers. Programs also may be more attractive if they use respected nonsmoking role models and peer support.
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Cotinine was measured in the serum of nearly all 5,115 18-30 year old, Black and White, men and women participating in the Coronary Artery Risk Development in (Young) Adults Study, 30 percent of whom reported current cigarette smoking. Ninety-five percent of the reported smokers had serum cotinine levels indicative of smoking (greater than 13 ng/ml). The median cotinine level was higher in Black than White smokers (221 ng/ml versus 170 ng/ml; 95 percent CI for difference: 34, 65) in spite of the fact that estimated daily nicotine exposure and serum thiocyanate were higher in Whites. The difference persisted after controlling for number of cigarettes, nicotine content, frequency of inhalation, weekly sidestream smoke exposure, age, gender, and education. A reporting bias and nicotine intake were ruled out as explanations for the racial difference suggesting that the metabolism of nicotine or the excretion of cotinine may differ by race. Racial differences in cotinine levels may provide clues to the reasons for the observed lower cessation rates and higher rates of some smoking-related cancers in Blacks.
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A sample of adult Black policyholders of the nation's largest Black-owned life insurance company was surveyed in 1986 to add to limited data on smoking and quitting patterns among Black Americans, and to provide direction for cessation initiatives targeted to Black smokers. Forty per cent of 2,958 age-eligible policyholders for whom current addresses were available returned a completed questionnaire. Population estimates for smoking status agree closely with national estimates for Blacks age 21-60 years: 50 per cent never-smokers; 36 per cent current smokers; 14 per cent ex-smokers. Current and ex-smokers reported a modal low-rate/high nicotine menthol smoking pattern. Current smokers reported a mean of 3.8 serious quit attempts, a strong desire and intention to quit smoking, and limited past use of effective quit smoking treatments and self-help resources. Correlates of motivation to quit smoking were similar to those found among smokers in the general population, including smoking-related illnesses and medical advice to quit smoking, previous quit attempts, beliefs in smoking-related health harms/quitting benefits, and expected social support for quitting. Methodological limitations and implications for the design of needed Black-focused quit smoking initiatives are discussed.
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In a retrospective study, interviews were obtained with 3,716 patients with histologically proven cancer of the lung (Kreyberg types I and II), mouth, larynx, esophagus, or bladder and with over 18,000 controls. For each of these cancers, the relative risk of both male and female present smokers increased with the quantity smoked and the duration of the habit. The strongest increase occurred for cancer of the lung and larynx, and the least increase occurred for cancer of the esophagus and bladder. For exsmokers the risk decreased with years of cessation. The risk for mouth cancer of pipe and cigar smokers who inhaled much less than cigarette smokers was less than that of the latter and increased with the quantity smoked. The risk of mouth, larynx, and esophagus cancer among smokers increased with the quantity of alcohol consumed. Greater smoking habits and lesser cessation rates were noted among lower socioeconomic groups, suggesting that these groups will bear an ever increasing proportion of the burden of tobacco-related cancer.
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Mentholated cigarette use was studied in relation to age and race in 29,037 current smokers who were Kaiser Permanente Medical Care Program members. The percentages of mentholated cigarette users were much higher in Blacks and Asians than in Whites, especially in the younger age groups. A marked inverse relationship between mentholated cigarette use and age was present in Blacks and Asians; mentholated cigarette use showed little difference with age in Whites.
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The lung cancer risk factors of smoking prevalence, amount smoked, and age started to smoke were compared for blacks and whites, using the 1970 and 1979/80 National Health Interview Survey (NHIS) survey data. For both survey years, proportionally more blacks were never smokers and fewer were ever smokers (although more were current and fewer former smokers). The average adult black smoker smoked approximately 65% of the number of cigarettes smoked by the average white adult. Blacks started smoking later than whites for almost all occupational categories. Thus, it could be argued that whites had higher smoking-associated risk factors than did blacks. At the same time, a much greater proportion of blacks than whites were in the types of occupation where they would have been exposed to occupational hazards. The sharp rise in and the larger incidence of lung cancer among blacks compared to whites may not be due to differences in black and white smoking, but more likely are a reflection of occupational differences.
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Anecdotal evidence indicates that the cigarette industry is targeting the sale of specific brands, notably menthol cigarettes, to black consumers. This paper presents data on the types of cigarettes smoked by white and black smokers. The cigarette brand preferences of two populations of smokers were examined. The first comprised 70 white and 365 black adult smokers seen at the Deaconness Family Medicine Center located in Buffalo, NY. The second population included 1,070 white and 92 black smokers who called a Stop Smoking Hotline in Buffalo. The results showed that, in both populations, blacks were twice as likely to smoke mentholated cigarettes compared with whites. In an attempt to evaluate the targeting of cigarette ads to black smokers as a possible explanation for black-white differences in brand preferences, cigarette ads appearing in magazines targeted to predominantly white or black readers were compared. Cigarette ads appearing in seven magazines were reviewed, four directed to predominantly white readers (Newsweek, Time, People, Mademoiselle) and three with wide circulation among black audiences (Jet, Ebony, Essence). The results showed that the magazines targeted to black readers contained significantly more cigarette ads and more ads for menthol brand cigarettes than magazines similar in content but targeted to white readers. The observation that a higher percentage of blacks smoke menthol cigarettes than do whites is consistent with the findings regarding differences in the type of cigarette ads appearing in magazines intended for black or white readers. However, it is not possible to determine from this study whether cigarette advertising is the cause of the differences in preference of cigarette brands between white and black smokers. Future research focusing on understanding the reasons for cigarette brand preferences may provide ideas for anti smoking campaigns aimed at specific target groups.
Article
In 1982 the American Cancer Society (ACS) enrolled over 1.2 million American men and women in a prospective mortality study of cancer and other causes in relation to environmental and life-style factors. Biennial follow-up is planned through 1988. At the time of enrollment, 23.6% of the men and 20.0% of the women were current smokers of cigarettes. Compared with a similar ACS study of 1 million subjects enrolled 23 years earlier, among men the proportion of current smokers was halved and that of ex-smokers doubled, while among women the proportion of ever-smokers increased by 10% and that of ex-smokers quadrupled. Most smokers of filter cigarettes had smoked nonfiltered cigarettes earlier in life. The median year for switching to filters was 1964, the year of the first Surgeon General's report. More than one-third of male smokers' and one-half of female smokers' current brands had tar yields below 12 mg; less than 9% of male smokers' and 4% of female smokers' current brands had tar yields of 20.2 mg or more (nonfilters). The study population differed in many respects from the general U.S. population; the study population had, for example, a much higher average educational level. Nevertheless, distributions of smoking habits changed a few percentage points after adjustment to the educational level of the general population.
Health Prom on and Disease Peeion United States Washing-ton, DC: Public Health Service
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US Department of Health and Human Services. Health Prom on and Disease Peeion United States, 1985. Washing-ton, DC: Public Health Service; 1988. DHHSPublicationNo. (PHS)88-1591. National Health Survey, series 10, No. 163.