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Naturalistic follow-up of a behavioral treatment for chronically parasuicidal borderline patients

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A randomized clinical trial was conducted to evaluate whether the superior performance of dialectical behavior therapy (DBT), a psychosocial treatment for borderline personality disorder, compared with treatment-as-usual in the community, is maintained during a 1-year posttreatment follow-up. We analyzed 39 women who met criteria for borderline personality disorder, defined by Gunderson's Diagnostic Interview for Borderline Personality Disorder and DSM-III-R criteria, and who had a history of parasuicidal behavior. Subjects were randomly assigned either to 1 year of DBT, a cognitive behavioral therapy that combines individual psychotherapy with group behavioral skills training, or to treatment-as-usual, which may or may not have included individual psychotherapy. Efficacy was measured on parasuicidal behavior (Parasuicide History Interview), psychiatric inpatient days (Treatment History Interview), anger (State-Trait Anger Scale), global functioning (Global Assessment Scale), and social adjustment (Social Adjustment Scale--Interview and Social Adjustment Scale--Self-Report). Subjects were assessed at 6 and 12 months into the follow-up year. Comparison of the two conditions revealed that throughout the follow-up year, DBT subjects had significantly higher Global Assessment Scale scores. During the initial 6 months of the follow-up, DBT subjects had significantly less parasuicidal behavior, less anger, and better self-reported social adjustment. During the final 6 months, DBT subjects had significantly fewer psychiatric inpatient days and better interviewer-rated social adjustment. In general, the superiority of DBT over treatment-as-usual, found in previous studies at the completion of 1 year of treatment, was retained during a 1-year follow-up.
... Dialectical Behavior Therapy (DBT) is a behaviorally oriented outpatient psychotherapy developed specifically for the treatment of chronically parasuicidal individuals [Linehan, 1987[Linehan, , 1989[Linehan, , 1993Linehan, Tutek, Heard, & Armstrong, 1994;Linehan, Heard, & Armstrong 1993;Linehan, Armstrong, Suarez, Allmon, & Heard, 1991]. Life-threatening and self-destructive behaviors are systematically addressed in a treatment hierarchy, including behaviors that interfere with the process of therapy. ...
... and had a lower attrition rate (16.7% vs. 50%) from individual therapy [Linehan, Armstrong, Suarez, Allmon, & Heard, 1991]. Other studies resulted in similar conclusions [Linehan et al., 1994;Linehan et al., 1993]. ...
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Recent research on the relationship between borderline personality disorder (BPD) and suicidal behavior is reviewed. Risk factors for attempted and completed suicide as well as the effect of the comorbidity of BPD with other Axis I and II disorders are considered. Explanations for suicidality in BPD are discussed. General assessment strategies are offered, along with treatment recommendations. Specifically, research has shown that borderline patients improve in the long-term, decreasing in suicidality, self-destructiveness, and interpersonal maladjustment, if survival is effectively managed during the turbulent years of youth. Clinical lore at times can lead clinicians to disregard the danger of suicide completion among chronically parasuicidal patients, which can prevent effective intervention during suicidal crises and result in unfortunate outcomes.
... They also showed that IPSRT helps to reduce depression episodes of BD better than medication. Furthermore, it was reported that IPSRT improved mood disorders (see Table 2 for more information) [122][123][124][125][126][127]. ...
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Bipolar disorder (BD) is a debilitating psychiatric disorder characterized by recurrent depression, mania, and hypomania episodes. The interaction of psychological, neuropsychological, and neurobiological factors (cognitive, behavioral, and emotional) is implicated in the development and persistence of BD. Accordingly, almost all investigators confirm that BD is the outcome of psychological and genetic interactions. Therefore, researchers should consider various factors in the psychopathology and psychotherapy of BD. This selective review first reviews research on these factors, then points to a variety of therapeutic methods for BD [interpersonal and social rhythm therapy (IPSRT), cognitive behavioral therapy (CBT), dialectical behavior therapy (DBT), mindfulness-based cognitive therapy (MBCT), and family-focused therapy (FFT)], and finally suggested a new comprehensive integrated model for the assessment and therapy of BD.
... This type of third-generation therapy keeps in mind the subjects personal goals while following structured protocols with well-de ned, replicable, objectives (9,10). DBT is the most e cacious treatment for borderline personality disorder (11,12), and it has been effective as a monotherapy in people with addictions (13), suicidal ideation (14), post-traumatic stress disorder (15), among others. It has also been speci cally adapted for use in adolescents (DBT-A) (16). ...
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Background Dialectic behavioral therapy (DBT) is a psychotherapeutic treatment to address emotional dysregulation (EDys) through acceptance and change strategies. It has been specifically adapted for use in adolescents (DBT-A). The aim of this study was to determine the effectiveness of a DBT-A skills training program in two different group formats, compared with standard care, for the treatment of EDys and depressive symptoms in adolescents. Methods We carried out a prospective cohort study on adolescents who were exposed to DBT-A skills training compared with standard care. The program included 14 sessions, two hours in duration, fortnightly. We examined clinical outcomes and measures of EDys (with the Difficulties in Emotion Regulation Scale - DERS) and depression (with the Children’s Depression Inventory - CDI) in three groups: Group A corresponded to separate DBT group skills training for patients and their caregivers; Group B-Multifamily, in which adolescents and their caregivers participated in the same sessions; and Group C was the treatment as usual group, with no DBT skills training. Group assignment was non-random and was subject to training group availability at time of inclusion. Linear models were used to control the effect of potential confounders. Results We identified a final sample of 130 subjects. Groups were significantly different only in sex distribution, and problematic alcohol/substance use. Significant differences in DERS and CDI scores were observed when comparing training groups (A and B) with the control (ANOVA p value < 0.001). The adjusted model for the difference in DERS scores showed a significant association between either of the intervention groups vs. treatment as usual. The model for change in the CDI scores showed a significant effect of Group B assignment over treatment as usual, but not of group A. Age showed a significant effect with an average decrease in the difference between pre and post scores of -1.207 per year (95%CI -2.292;-0.122). The use of antidepressants showed a significant effect with a magnitude of 5.411 (95%CI 1.415;9.407). Conclusions The implementation of DBT-A skills training, in either a separate or multifamily format, was both effective and safe for EDys treatment. DBT-A skills training delivered in a multifamily format may have the added benefit of impacting symptoms of depression.
... Complex psychological treatment is the only strategy with any evidence for effectiveness for borderline personality disorder (Linehan, Armstrong, Suarez, Allmon, & Heard, 1991), and follow-up studies indicate that these gains are maintained (Linehan, Heard, & Armstrong, 1993). Furthermore, as one might expect, for a chronic personality disorder, this treatment is long-term psychotherapy lasting at least one year, probably longer in the typical case. ...
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In a quest for accountability in the delivery of health services, health care policymakers in both government and private sectors are creating clinical practice guidelines, many of which heavily emphasize medical and pharmacological approaches. Yet, there are now sufficient data to support the efficacy of psychotherapeutic procedures for a wide variety of specific disorders, and it seems now is the appropriate time to communicate these findings to health care policymakers and the public at large. At the same time, data must be developed on the delivery of these interventions by frontline clinicians in the settings where they practice. The emergence of practice research networks may accomplish this latter goal.
... This type of third-generation therapy keeps in mind the subjects personal goals while following structured protocols with well-de ned, replicable, objectives (9,10). DBT is the most e cacious treatment for borderline personality disorder (11,12), and it has been effective as a monotherapy in people with addictions (13), suicidal ideation (14), post-traumatic stress disorder (15), among others. It has also been speci cally adapted for use in adolescents (DBT-A) (16). ...
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Full-text available
Background Dialectic behavioral therapy (DBT) is a psychotherapeutic treatment to address emotional dysregulation (EDys) through acceptance and change strategies. It has been specifically adapted for use in adolescents (DBT-A). The aim of this study was to determine the effectiveness of a DBT-A skills training program in two different group formats, compared with standard care, for the treatment of EDys and depressive symptoms in adolescents. Methods This study is a prospective cohort on adolescents who were exposed to DBT-A skills training compared with standard care. The program included 14 sessions, two hours in duration, fortnightly. We examined clinical outcomes and measures of EDys (with the Difficulties in Emotion Regulation Scale - DERS) and depression (with the Children’s Depression Inventory - CDI) in three groups: Group A corresponded to separate DBT group skills training for patients and their caregivers; Group B-Multifamily, in which adolescents and their caregivers participated in the same sessions; and Group C was the treatment as usual group, with no DBT skills training. Results We identified 331 adolescents who met the inclusion criteria, 201 subjects were excluded, leaving a final sample of 130 subjects. Groups were significantly different only in sex distribution, and problematic alcohol/substance use. Significant differences in DERS and CDI scores were observed when comparing intervention groups A and B with control Group C (ANOVA p value < 0.001). The adjusted model for the difference in DERS scores showed a significant association between either of the intervention groups vs. treatment as usual. The model for change in the CDI scores showed a significant effect of Group B assignment over treatment as usual, but not of group A. Additionally, age showed a significant effect with an average decrease in the difference between pre and post scores of -1.207 per year (95%CI -2.292; -0.122). The use of antidepressants also showed a significant effect with a magnitude of 5.411 (95%CI 1.415; 9.407). Conclusions The implementation of DBT-A skills training, in either a separate or multifamily format, was both effective and safe for EDys treatment. DBT-A skills training delivered in a multifamily format may have the added benefit of impacting symptoms of depression.
... Nowadays the interactions based on mindfulness, enriched with the diversity of therapeutical approaches, are becoming more and more popular, for example in ACT (Hayes et al., 2012), DBT (Linehan et al., 1994), MBCT (Segal et al., 2018). They put special emphasis on the role of acceptance in the regulation of the emotional process. ...
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Objective Emotion regulation is an adaptive ability affecting people’s physical and mental health, quality of life and functioning. In the present study we focused on the influence of the intensity of experienced emotions on emotion regulation strategies (ERS) that are applied in everyday life. Methods For 7 days the participants kept an online diary where every day they described the situation which had aroused their strongest negative emotions. Next, they identified the emotions, their intensity and the type of applied strategies (acceptance vs. reappraisal vs. rumination vs. distraction vs. suppression). The study involved 88 people N = 88, which gives 538 observations. Results The obtained results indicate that the intensity of emotions affects the choice of regulation strategies. When the intensity increases, people are more likely to choose the rumination strategy and less likely to choose the reappraisal strategy. However, the expected relationship between the intensity and the number of regulation strategies was not confirmed. In turn, it was gender (male) that turned out to be associated with a greater number of strategies used. Conclusion The concern of this research was to look at making regulatory decisions in personally relevant and complex everyday situations. Although the emotions experienced in response to a difficult situation were varied, the intensity of the emotional experience was an important factor determining the choice of a regulation strategy. It indicates that this emotional dimension is a basic and determining aspect in people’s regulatory capabilities. These results also indicate that perhaps men in a situation perceived as stressful and worthy of emotional involvement use more regulatory strategies than women. These findings may find an application in all kinds of psychological interventions (e.g., psychotherapy, anger management therapies).
... DBT is a gold-standard treatment for those with borderline personality disorder, who struggle with emotion dysregulation and distress tolerance (Linehan, 2015;Linehan et al., 1991Linehan et al., , 2015. Additionally, there is some evidence that DBT skills training can be an effective treatment for chronic pain, with improvements in emotion regulation, decreased pain intensity and catastrophizing, as well as with mood, coping behaviors, sleep, and general well-being (Linton & Fruzzetti, 2014;Norman-Nott et al., 2022). ...
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Persistent genital arousal disorder/genitopelvic dysesthesia (PGAD/GPD) is characterized by persistent, unwanted physiological genital arousal (i.e., sensitivity, fullness, and/or swelling) in the absence of sexual excitement or desire which can persist for hours to days and causes significant impairment in psychosocial well-being (e.g., distress) and daily functioning. The etiology and course of PGAD/GPD is still relatively unknown and, unsurprisingly, there are not yet clear evidence-based treatment recommendations for those suffering from PGAD/GPD. We present the case of a 58-year-old woman with acquired persistent genital arousal disorder, which began in March 2020; she believed she developed PGAD/GPD due to a period of significant distress and anxiety related to the COVID-19 pandemic. After seeking medical diagnosis and treatment from multiple healthcare providers and trying a combination of pharmacological and medical treatment modalities, she presented for psychological treatment. An integrative therapy approach (3 assessment sessions, 11 treatment sessions), which included cognitive behavior therapy, distress tolerance and emotion regulation skills from dialectical behavior therapy, and mindfulness practice, was utilized. The patient reported improvements anecdotally (e.g., decreased impact on occupational and social functioning, greater self-compassion, less frequent and shorter duration of PGAD/GPD flare-ups, improved ability to cope with PGAD/GPD symptoms, and decreased need for sleeping medication) and on self-report measures (e.g., lower PGAD/GPD catastrophizing, lower anxiety and depression, and greater overall quality of life).We report the use of an integrative (i.e., psychoeducational, cognitive behavioral, dialectical behavioral, and mindfulness-based) intervention, which may be an effective psychological treatment for PGAD/GPD.
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Systematic reviews and meta-analyses typically require significant time and effort. Machine learning models have the potential to enhance screening efficiency in these processes. To effectively evaluate such models, fully labeled datasets—detailing all records screened by humans and their labeling decisions—are imperative. This paper presents the creation of a comprehensive dataset for a systematic review of treatments for Borderline Personality Disorder, as reported by Oud et al. (2018) for running a simulation study. The authors adhered to the PRISMA guidelines and published both the search query and the list of included records, but the complete dataset with all labels was not disclosed. We replicated their search and, facing the absence of initial screening data, introduced a Noisy Label Filter (NLF) procedure using active learning to validate noisy labels. Following the NLF application, no further relevant records were found. A simulation study employing the reconstructed dataset demonstrated that active learning could reduce screening time by 82.30% compared to random reading. The paper discusses potential causes for discrepancies, provides recommendations, and introduces a decision tree to assist in reconstructing datasets for the purpose of running simulation studies. Supplementary Information The online version contains supplementary material available at 10.1186/s13643-024-02472-w.
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Borderline personality disorder (BPD) is thought to develop by early adulthood, and it is characterized by lack of control of anger, intense and frequent mood changes, impulsive acts, disturbed interpersonal relationships, and life-threatening behaviors. We describe data from a 2-year follow-up study of nonclinical young adults who, at study entry, exhibited a significant number of BPD features. Individuals with borderline features were more likely to have academic difficulties over the succeeding 2 years, and these participants were more likely to meet lifetime criteria for a mood disorder and to experience interpersonal dysfunction than their peers at the 2-year follow-up assessment. These findings indicate that BPD features are associated with poorer outcome even within a nonclinical population.
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Background: Identity diffusion plays a central role in the onset of borderline personality disorders. Dialectical Behavioral Therapy for Adolescents (DBT-A) is a treatment program for adolescents with emotional instability and dysregulation. The interest of this study is to examine the potential effects of a standardized and certified DBT-A therapy program on the identity development of adolescents in an inpatient setting. Methods: A total of 138 adolescents aged 13 to 18 years with symptoms of severe emotional instability were assessed before and after a certified and standardized 12-week in-patient DBT-A program targeting emotional regulation with the following standardized instruments: the Assessment of Identity Development in Adolescence (AIDA), Scale of the Experience of Emotions (SEE), and Symptom Checklist (SCL-90-R). Results: The results indicate a significant change in identity development, emotion regulation, and general symptoms of psychopathology after treatment with DBT-A. Conclusions: In this large sample of adolescents, DBT-A significantly improved identity development and reduced identity diffusion, however, without a treatment-as-usual control group as a limitation. Nevertheless, our results may become clinically relevant for the prevention of chronic impairment in emotionally unstable adolescents.
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