Vivian Ezeh

Kenyon College

Oct-2-enitols undergo a Pd(0)-mediated cyclization to produce C-vinyl α-gluco- and α-galactopyranosides, and C-vinyl β-mannopyranoside in good yield and with high stereoselectivity. While substrate control demonstrates a clear stereochemical preference during cyclization, the α- and β-epimeric ratios are enhanced by double diastereoselection using...

The EPA has established a maximum contaminant level (MCL) of 10 ppb for arsenic (As) in drinking water requiring sensitive and selective detection methodologies. To tackle this challenge, we have been active in constructing small molecules that react specifically with As to furnish a new fluorescent species (termed a chemodosimeter). We report in t...

Arsenic contamination is a leading environmental problem. As such, levels of this toxic metalloid must be constantly monitored by reliable and low-cost methodologies. Because the currently accepted upper limit for arsenic in water is 10 ppb, very sensitive and selective detection strategies must be developed. Herein we describe the synthesis and ch...

Air-stable four-coordinate As(III) complexes, [As(L4)Cl] (1) and [As(L4)I] (2), were prepared using a rearranged form of the deprotonated benzothiazoline ligand, 2-(pyridin-2-yl)-2,3-dihydrobenzo[d]thiazole. Complexes 1 and 2 have been characterized by FTIR, (1)H NMR, UV-vis, and elemental microanalysis. The solid-state structure of 2 was also solv...

The equilibrium constant of the reaction of 5,5'-dithiobis(2-nitrobenzoate) with the CysF9[93]beta sulfhydryl group of hemoglobin decreases by 2 to 3 orders of magnitude between pH 5.6 and 9. The reaction is coupled to the ionizations of two groups on the protein. At 25 degrees C one group has a pK(a) of 5.31+/-0.2 when hemoglobin is in its (tertia...