Veena D Singh

Shri Rawatpura Sarkar college of Pharmacy · Pharmacy

Aim of study: To isolate bioactive compound from methanolic extract of Carica papaya leaves (MECPL) and investigate their anti-inflammatory potential. Material and Methods: Soxhlet extraction of C. papaya leaves powder was performed by using methanol as a solvent. The isolation of MECPL extract was performed by using column chromatography. All frac...

Background Emtricitabine (ETC), Tenofovir disoproxil fumarate (TNF), Elvitegravir (EVG), and Cobicistat (CBS) are antiviral drugs used to treat human immunodeficiency virus (HIV) infections. Objective To develop chemometric-aided UV spectrophotometric methods for concurrent estimation of the aforementioned drugs used to treat HIV. This method can...

Background: Cancer is an ailment with having a very low survival rate globally. Poor cancer prognosis is primarily caused by the fact that people are found to have the disease when it is already well advanced. The goal of this study is to compile information on new avenues of investigation into biomarkers that may facilitate the routine detection...

Alzheimer's disease (AD) is a neurological condition characterised by cognitive and behavioural dysfunction. The presence of the blood brain barrier (BBB), which prevents medications from entering the brain, makes treating AD difficult. Currently, existing therapeutic modalities provide symptomatic alleviation while also being unsafe. Phytoconstitu...

Inflammation of the lining of the stomach is one of the most prevalent health problems that people face. In this study, the effects of herbal medication on the digestive system were examined in relation to the use of the cold-water immersion technique. Material & Methods: Male albino 6-week-old albino rats weighing 200-250 g each were used in the i...

Psoriasis is an autoimmune inflammatory skin disorder that affects 2–3% of the world's population. It has distinct features, such as accelerated keratinocyte proliferation and proinflammatory cytokines secretion. Topical, systemic, phototherapy, and biologic therapies are used in the treatment. Topical therapies are preferred over systemic medicine...

This study aims to carry out the extraction and isolation of bioactive compounds from the peel of Punica Granatum Linn and investigate the wound healing activity of isolated compounds. Soxhlet extraction of P. Granatum peel powder was done with ethanol as solvent. The isolation of phytochemical constituents, Punicalin and Punicalagin present in the...

New HPTLC method was developed and optimized for estimation of Ondansetron (OND), Dexamethasone (DEX) and Aprepitant (APT) in laboratory prepared ternary mixtures by using Central composite design (CCD). The independent variables used for the optimization were the acetone content in mobile phase (%mL), distance of developing solvent (cm) and satura...

This research work was emphasis to adopt green analytical chemistry via development of environmentally friendly methods for simultaneously estimation of drugs used for chemotherapy induced nausea and vomiting (CINV). In these study two multivariate calibration methods namely; Partial least square (PLS) models, Principal component regression (PCR) a...

Colorectal cancer (CRC) is a major cause of mortality and highly prevalent worldwide. Currently, no effective delivery system is available for clinical use which could specifically target metastatic cancers. Due to the complicated and variable metastasis process, the current treatment methods for colorectal cancer liver metastasis cannot meet the c...

Darunavir ethanolate (DRV) and Cobicistat (CBS) is a combination of antiretroviral drugs used for the treatment of human immunodeficiency virus (HIV) infections. Two Chemo-metric assisted UV-spectrophotometric methods were developed for simultaneous estimation of DRV and CBS in tablet dosage form, namely; partial least square (PLS) and Classical le...

A simple, sensitive, cost effective and robust RP-HPLC method for the simultaneous estimation of the Lamivudine (LAM) and Raltegravir (RAL) in laboratory prepared binary mixture was developed, optimized and validated. Separation was achieved on phenomenex C18 column (150 X 4.6 mm id, 5μ particle size) and mobile phase was composed of 75% methanol:...

Threemultivariate calibration spectrophotometric methodswere developed for simultaneous estimation of Paracetamol (PARA), Enalapril maleate (ENM) and Hydrochlorothiazide (HCTZ) in tablet dosage form; namely multilinear regression calibration (MLRC), trilinear regression calibration method (TLRC) and classical least square (CLS) method. The selectiv...

The present investigation is an attempt to study the formulation and evaluation of matrix tablet of Metformin HCl using natural mucilage of Cassia tora as a release retardant. The matrix tablet was formulated using different drug polymer ratio. The result of the pre-compression parameter like bulk density, tapped density, carr’s index and hausner r...

Context: Ambroxol Hcl is an active metabolite of bromohexine. It is an expectoration improver and a mucolytic agent used in the treatment of bronchial asthma and chronic bronchitis.The available formulation of Ambroxol was authorized first in market since 1978. Objective:This article highlights on published analytical methods reported in the litera...

Ethnopharmacological relevance: The plant Diospyros melanoxylon (Roxb) belongs to the family Ebenaceae that is native to India and Sri-lanka. This is a medium-sized tree, reaching a height of 15 m and is well known for its beedi making leaves throughout the world. The purpose of the present study is to assess the effect of Diospyros melanoxylon le...

The development and formulation of the pharmaceuticals brought a revolution in human health. These pharmaceuticals would help their intent only if they are free from impurities and are administered in an appropriate quantity. Hence, there are having many challenges and it can be reduced by effective use of excipients, which permits formulators to o...

The study of management of house dust mites with herbal extracts in Lambani households was carried out in Dharwad district during 1997-98 Results revealed that the leaf extracts when applied with 1:100 dilution, resulted in low per cent of mortality of house dust mites Hence leaf extract was not used for further study. When seed extracts were used...