Kancharla Suman

Mylan Laboratories · Chemical Research & development

p> Background: Heterocyclic compounds containing heteroatoms (O, N and S) attracted recently as potential molecules for various applications such as pharmaceutical drugs, agrochemical products and organic materials. Among many known heterocyclic moieties, quinolines and its derivatives are one of the privileged scaffolds found in many natural produ...

Background: The 3,4-diyne substituted isocoumarins have been designed, synthesized and explored as potential anti-proliferative agents. Method: Ultrasound assisted synthesis of these compounds was carried out by using a three-step method involving (i) Pd/C-Cu catalyzed cross-coupling between the methyl 2-iodobenzoate and buta- 1,3-diynylbenzene...

Background: 3-Methyleneisoindolin-1-one derivatives containing a pyridin-2-ylmethyl substituent on their ring nitrogen were designed as potential bioactive agents. A one-pot synthesis of these compounds was achieved via sequential C-C coupling, followed by C-Si bond cleavage and subsequent tandem C-C/C-N bond forming reaction under ultrasound irra...

Genus Habenaria belongs to the family Orchidaceae and H. intermedia & H. edgeworthii are two species mentioned as drugs of Astavargha group of having antioxidant and anti ageing activity for a long time in ancient text of Ayurvedic literature. The increasing demand has resulted in commercial harvesting pressure on wild populations and that were alr...

Till recently dedicated hardware has been required to perform real-time MPEG-2 video encoding.

Till recently dedicated hardware has been required to perform real-time MPEG-2 video encoding. However, with increase in clock frequency and the introduction of video-specific instruction sets, general-purpose processors and DSPs can now approximate the function and performance of single-function hardware. In this paper, a software-only MPEG-2(MP@M...

A fast motion vector estimation algorithm for Field Motion Estimation having computational complexity independent of search range is presented for interlaced video encoding. The algorithm is based on spatial correlation of motion vectors and yields good tradeoff between motion estimation distortion and number of SAD computations. The speed up achie...

International video compression standards provide bit-stream syntax for decoders. The standards offer enough flexibility to control various features at encoding so that continuous improvement in the quality and performance of encoders can take place. Innovative algorithms can be used in motion estimation (ME), rate control, usage of interlaced tool...

A fast motion vector estimation algorithm for Field Motion Estimation having computational complexity independent of search range is presented for interlaced video encoding. The algorithm is based on spatial correlation of motion vectors and yields good tradeoff between motion estimation distortion and number of SAD computations. The speed up achie...

We report three cases of biopsy proven pancreatic tuberculosis. The patients presented with abdominal pain and intermittent fever. Ultrasound and computed tomography revealed a diffusely enlarged pancreas with focal hypoechoic/hypodense lesions in all three patients. In addition, one patient had a large pancreatic cyst with internal echoes. Associa...

A study was undertaken to determine the usefulness of ultrasonography as an investigative tool, and its role in deciding the management of Peyronie's disease. Fifteen patients with Peyronie's disease were studied by ultrasonography. The plaque could be demonstrated in all patients. The dimensions of the plaque varied from less than 1 cm to more tha...

Forty-six patients with peripheral lung lesions underwent ultrasound-guided percutaneous needle aspiration biopsy. Aspirates were sent for cytological and/or microbiological examination. Confirmative diagnosis was obtained in 40 patients (86.9%). Twenty-eight patients had positive cytology for malignancy and 12 patients with benign lesions had diag...