Sivanantham Krishnamoorthi

All India Institute of Medical Sciences, India, Bathinda · Microbiology

We developed a rapid multiplex loop-mediated isothermal amplification (mLAMP) assay for two common intestinal parasites—Entamoeba histolytica and Giardia duodenalis, where early detection may be helpful. The mLAMP assay was optimized for detection of DNA of E. histolytica (18S rRNA gene) and G. duodenalis (Elongation factor 1 alfa gene) from standa...

Rickettsial diseases (RD) are widely reported all over the world. Scrub typhus (ST) is a major tropical infection which is well documented all over India. Therefore, the index of suspicion of scrub typhus is high among physicians with regard to patients presenting with acute febrile illness (AFI) and acute undifferentiated febrile illness (AUFI) in...

Background: Hand hygiene is a significant component involved in preventing transmission of health care associated infections including COVID-19. Compliance to hand hygiene among the health care workers (HCWs) requires evaluation and timely feedback. "You can't improve what you can't measure" is a famous saying and this multicentric study was design...

Purpose: Hand hygiene (HH), the core element in infection prevention in healthcare, especially for multidrug resistant organism's transmission. The role of HH audits and HH adherence rates in the COVID-19 pandemic, especially in resource limited settings, are yet to be established. Methods: A nationwide multicenter study was conducted in India, inv...

Background: Hand hygiene is a significant component involved in preventing transmission of health care associated infections including COVID-19. Compliance to hand hygiene among the health care workers (HCWs) requires evaluation and timely feedback. "You can't improve what you can't measure" is a famous saying and this multicentric study was design...

Background: Hand hygiene is a significant component involved in preventing transmission of health care associated infections including COVID-19. Compliance to hand hygiene among the health care workers (HCWs) requires evaluation and timely feedback. "You can't improve what you can't measure" is a famous saying and this multicentric study was design...

Background: Hand hygiene is a significant component involved in preventing transmission of healthcare associated infections including COVID-19. Compliance to hand hygiene among the healthcare workers (HCWs) requires evaluation and timely feedback. “You can't improve what you can't measure” is a famous saying and this multicentric study was designed...

Impact of conducting hand hygiene audit in COVID-19 care locations of India—A large scale national multicentric study –HHAC study

Background: Antifungal stewardship is a less explored component of antimicrobial stewardship programs, especially in developing countries. Objective: We aimed to determine antifungal prescription practices in a tertiary centre of a developing country to identify the challenges for antifungal stewardship programs. Methods: Four single-day point...

Purpose Free-living amoebae (FLA) exist in various environmental sources and are the causative agents of many serious human diseases. We surveyed various natural and artificial water bodies in areas of north India to detect the presence of FLA species. Materials and methods Surface water samples were collected from 29 water bodies and subjected to...

Cervicitis is predominantly caused by N. gonorrhoeae and C. trachomatis, which accounts for almost half of all the cases of cervicitis. The role of newer organisms like Mycoplasma genitalium and Ureaplasma spp. and association of bacterial load with cervicitis are also not well established. So the study aimed to determine the relative frequency of...

Rickettsial diseases (RDs) are major under-diagnosed causes of arthropod borne acute febrile illness (AFI) presenting with a range of symptoms from mild self-limiting fever to fatal sepsis. The spotted fever group (SFG) and typhus group (TG) are major RDs, which are commonly caused by Rickettsia conorii and Rickettsia typhi, respectively. The limit...

A 19-year-old previously healthy male presented with generalized weakness and chronic abdominal pain over a period of 2 years. The abdominal pain was characterized by dull aching confined to the lower abdomen and was occasionally associated with cramping. He endorsed indigestion, unintentional weight loss of 10 kilograms over the past two years, an...

Bevacizumab, a recombinant humanized monoclonal antibody to inhibit tumour-angiogenesis is available for off-label use for treating choroidal neovascularisation. Outbreaks have been reported after use of this drug, either because of contamination during manufacturing or the practice of multiple doses being administered from a single vial to differe...