Shushanik Kazarian

Russian - Armenian (Slavonic) University · Department of Medical Biochemistry

Nanotechnology is an advanced and promising field that focuses on creating unique nanoparticles with various properties. Among them, silver-based nanoparticles have gained significant attention and are extensively studied. The liver and kidney are particularly vulnerable to AgNPs because they play a crucial role in excreting exogenous substances.Th...

The widespread use of silver nanoparticles (AgNPs) requires a study of their safety. The aim of the present study was to assess the levels of oxidative stress markers and histopathological changes in the experimental model of sarcoma S-180 of outbred mice caused by biogenic AgNPs. AgNPs were synthesized using 50% ethanol extract of Ocimum araratum...

For the use of iron oxide nanoparticles (NPs) for medical purposes, they must have the following properties: low cytotoxicity, bioavailability, the possibility of large-scale production, etc. Nowadays, there are many approaches for the iron oxide NPs synthesis, including chemical, biological, physical methods, etc. In this research, a comparative a...

The emergence of antibiotic-resistant bacterial strains leads to the need to find new antibacterial agents. Due to their properties, silver nanoparticles and plant extracts are more often considered as promising antibacterial agents. The aim of this work was to study the antibacterial properties of silver nanoparticles and evaluate the potential ef...

Nanoparticles green synthesis by plants and extracts is very cost-effective and can be used as an economic and environment friendly alternative in large-scale production. But the effect of these structures on the liver isn’t fully investigated. In this study green silver nanoparticles (AgNPs) were synthesized by O. araratum 50% ethanol extract that...

Antibiotic resistance is one of the main public health problems. The increase in the occurrence of multi-resistant pathogenic strains of bacteria due to biofilm formation gradually leads to inefficiency of traditional antibiotics. There are many strategies to combat biofilms, such as nanotechnologies. It is extremely important and relevant for nano...

The plant Prunella vulgaris L. has long been used in traditional European and Asian medicine. Its extracts reveal immunoprotective, antitumor, antiinflammatory, and antiestrogenic features. We obtained aqueous and ethanol extracts from P. vulgaris L. leaves; carried out HPLC analysis; detected the total flavonoids content and the antiradical activi...

In present study effect of laurel leaf extract (Laurus nobilis) on biochemical parameters and histomorphology of rat liver induced by toxic damage of CCl4 was studied. Introduction of CCl4 in animals was always carried out in fatal to 36 hours. A single injection of the L. nobilis extract ssimultaneously with CCl4 leads to 100% survivability. To ev...