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Shigeki Horiuchi

Shigeki Horiuchi

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116
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Publications

Publications (116)
Article
An earthquake has occurred at 10:22:33 UT on 5 August 2014 in the Klerksdorp district, the North West province of South Africa. Its hypocenter is located beneath an Orkney town, where more than 10 gold mines exist. The Council for Geoscience (CGS) in South Africa reported that the magnitude and depth was ML5.5 and 4.7 km, respectively. CGS has been...
Article
Three months of acoustic emission (AE) monitoring in a South African gold mine down to MW –5 revealed a newly emergent planar cluster of 7557 events –3.9 ≤ MW ≤ –1.8 (typical rupture radius of 6–70 cm) that expanded with time to reach a size of 20 m on a preexisting geological fault near an active mining front 1 km beneath the ground. It had a shar...
Conference Paper
Full-text available
A multi-disciplinary study of the response of the rock mass to mining and mining-induced earthquakes has been conducted in six gold mines in South Africa at sites deeper than 3 km, or with equivalent stress. More than 80 holes (with a total length of more than 2.8 km) were drilled in earthquake-prone areas to locate faults and install instruments....
Article
We conducted a three-dimensional traveltime tomographic reconstruction in and around the source region of the 1984 western Nagano Prefecture earthquake to investigate the generation process for the main shock and associated swarm activity. Up to 220 000 high-resolution traveltime records (2 ms error) were compiled from a dense seismic network. From...
Article
Full-text available
We investigated frequency-magnitude distribution (FMD) of acoustic emissions (AE) occurring near an active mining front in a South African gold mine, using a catalog developed from an AE network, which is capable of detecting AEs down to M W −5. When records of blasts were removed, FMDs of AEs obeyed a Gutenberg−Richter law with similar b values, n...
Article
Results of tomographic inversion enrich our understanding of the geodynamic processes in the Earth. Seismic imaging of fault zones, the shear rupture permits us to investigate the structure under gas storage areas, in districts of large hydroelectric power stations, nuclear plants. The information about the geodynamic evolution of seismic structure...
Article
In order to improve frequency-response estimation in earthquake early warning, we introduce a new source parameter, "frequency-response magnitude (Mres)" that can be calculated for each natural frequency from observed P-wave data using a pre-established attenuation relation. Users can easily estimate frequency responses of their target systems by u...
Article
We propose the method of the elevator operation control for the long-period ground motion using Earthquake Early Warning System (EEWS) and apply this method to the elevator operation control system of the 29-story building of Kogakuin University in the downtown Tokyo, Shinjuku, Japan. First, we estimate the velocity of surface wave that travels th...
Article
We found seismic reflectors aligned along the east side of the volcanic front in northeastern Honshu, Japan, by analyzing seismograms of intermediate-depth earthquakes recorded at High Sensitivity Seismograph Network Japan stations. We identified an unusual high-frequency later phase on the seismograms, which arrives after the direct S waves and co...
Article
Standard least squares method gives the possibility to cope with overdetermined inconsistent systems of linear equations. It is accepted that the more measurements will participate in the general inversion,the better solution will be obtained. However seismic data is special case of geophysical observations, which in practice have a large range of...
Article
Full-text available
We have investigated the spatial variation of the stress field along the fault rupture zone of the 1999 Izmit earthquake (M w 7.4) using first-motion polarity data at seven distinct aftershock clusters. In our approach, the first-motion polarities of all the aftershocks in a cluster are simultaneously inverted to determine the stress tensor paramet...
Article
Full-text available
Automatic pickings in earthquake real-time monitoring systems often contain noise bursts and/or phases of different event(s) occurring almost simultaneously. Typically, a locator uses these picks as P and S waves arrival times coming from a single event and, therefore, should be complemented by a distinctive phase association logic. The method we p...
Article
Full-text available
The Japan Meteorological Agency (JMA) has started the practical service of Earthquake Early Warning (EEW) and a very dense deployment of receiving units is expected in the near future. The receiving/alarm unit of an EEW system is equipped with a CPU and memory and is on-line via the internet. By adding an inexpensive seismometer and A/D converter,...
Article
Full-text available
The real-time earthquake information system (REIS) of the Japanese seismic network is developed for automatically determining earthquake parameters within a few seconds after the P-waves arrive at the closest stations using both the P-wave arrival times and the timing data that P-waves have not yet arrived at other stations. REIS results play a fun...
Article
Horiuchi et al. (2005) developed a real-time earthquake information system (REIS) using Hi-net, a densely deployed nationwide seismic network, which consists of about 800 stations operated by NIED, Japan. REIS determines hypocenter locations and earthquake magnitudes automatically within a few seconds after P waves arrive at the closest station and...
Article
Full-text available
The infamous Tokai Earthquake, which by some accounts is overdue, is expected to be a magnitude >= 8 event that will cause unprecedented damage in regions of Japan. To mitigate hazards from large earthquakes in Japan, an earthquake early warning (EEW) system was developed that is able to determine hypocentral locations from P-arrival data within a...
Chapter
In general, many earthquakes occur after a destructive shallow earthquake or before a volcanic eruption. It is very important to determine accurate hypocenters as first as possible at a time of such a huge seismic activity, since seismicity data are essential for the understanding of the seismic or volcanic activity. We developed an automatic data...
Article
Full-text available
We have developed an automated system for analyzing Hi-net seismograms for earthquake early warning (EEW) in Japan. Because of limitations imposed by station spacing, our system generally cannot issue an EEW to areas within about 30 km distance of the earthquake's hypocenter. We estimate that about 10 times the number of stations would be needed to...
Article
With the enhancement of regional seismic networks, real-time seismology becomes a practical way for effective damage mitigation. For example, using P-wave arrival times and amplitudes from only a few stations, a real-time earthquake analysis system developed by Horiuchi et al. (2004) can precisely locate the earthquake within a few seconds and issu...
Article
Full-text available
A reliable prediction of the shaking intensity from s-waves is the primary purpose of any earthquake early warning (EEW) system. To date, empirical regression formulae have been used to estimate this intensity from conventional seismic magnitude (e.g.,Mjma), which is the only parameter regarding earthquake size currently broadcast by an EEW. Others...
Article
Full-text available
Arising from: E. L. Olson & R. M. Allen Nature 438, 212–215 (2005); Olson & Allen reply
Article
Full-text available
An M=5 earthquake occurred on September 15, 1998, in the Nagamachi-Rifu fault (NRF), northeastern Japan. In the aftermath of this event, many seismograph stations were constructed temporarily around the fault, forming a dense network of stations with a spatial separation of 5 km. We report here our estimation of the three-dimensional velocity struc...
Article
We have developed an earthquake early warning system (EEWS) by using a spatially dense and high dynamic range seismic network that consists of 700 stations covering the Japanese Islands. The system is able to determine the hypocenter location, magnitude and a shaking intensity parameter within a few seconds from the P-wave arrivals at the closest s...
Article
Full-text available
A fundamental problem in seismology is earthquake location. It is especially important in real-time earthquake warning systems to locate a potentially hazardous earthquake as rapidly as possible in order to sound an alarm in the least amount of time. We have developed a method that uses only the two earliest p-wave arrival times in a seismic array....
Article
Japan is located in one of the most tectonically active region in the world. We have suffered from many disasters brought by earthquakes and tsunamis. Significant efforts to mitigate disasters have been made as one of the most important national programs. Considering the difficulty of the earthquake prediction in time, Japan Meteorological Agency (...
Article
We propose a method to estimate the probability of earthquake growth to a catastrophic one immediately after observing its initiation, for practical usage in an earthquake early warning system. This method is essentially an application of the conditional probability theory, where the magnitude-frequency relation plays a crucial role. We apply it to...
Article
In Japan, most of the damage caused by large earthquakes is concen-trated within areas less than about 100 km from the focal regions. We have developed an earthquake alarm system that determines earthquake parameters within a few seconds of the P wave's arrival at the closest station, and then transmits the earth-quake information before the S-wave...
Article
3D tomography using P- and S-wave arrivals was performed in a very small area of Tokachi-dake (8 x 6 km2) and two Mt Usu regions:Mt.Usu-1 (40 x 40 km2) and Mt. Usu-2 (140 x 170 km2), Hokkaido in order to investigate magma body changes and volcanic activities before and after the eruption. The high Vp/Vs anomalies greater than 1.97 in Tokachi-dake i...
Conference Paper
Full-text available
Three-dimensional seismic velocity structure in the region of the Nagamachi-Rifu fault, which passes through the center of Sendai City, northeastern (NE) Japan, was estimated by travel-time tomography. A low-Vp and low-Vs anomaly was detected close to the surface trace of the fault at depths down to 5 km,, probably due to the existence of thick lat...
Article
Most earthquake damage occurs after arrival of the S wave, whose amplitude is about five times larger than the P wave. Because the P wave travels faster than the S wave, the interval between their arrival times creates an opportunity to activate an earthquake alarm and take preemptive safety measures. We developed an automatic system which transmit...
Article
An extensive seismic network has been constructed nationwide composed of hi-sensitivity seismographic network, broadband seismographic network and strong motion seismographic network. All these data from some 3,000 sites belonging to NIED, JMA and universities are to be accumulated and distributed through NIED to any scientists and engineering thro...
Article
In the present analysis we introduced a calculation strategy of the staggered grid differentiation by using the real value FFT and real inverted FFT for the pseudospectral method and applied the technique to seismic wave simulation. The calculation method introduced here is one third faster on average than the traditional differentiation method by...
Article
We estimated the temperature distribution within the crust of the northeastern Japan arc from P wave velocity perturbations obtained by travel time tomography. By comparing the estimated temperature distribution with the focal depth distribution of shallow, precisely relocated microearthquakes, we found that the brittle to ductile or stick-slip to...
Article
A fine-scale three-dimensional attenuation structure beneath the northeastern Japan arc has been obtained using a joint inversion for source parameters, site response and Q values. Data used for this study are P wave spectra of microearthquakes occurring in the subducting Pacific plate. The subducting plate is found to have higher Q values than the...
Article
Development of new antiatherosclerotic agents were reviewed focusing on ACAT inhibitors and CETP inhibitors. ACAT inhibitors enhance intracellular degradation of VLDL in hepatocytes. Cholesterol absorption in small intestine is inhibited by ACAT inhibitors. Thus, ACAT inhibitors reduce plasma cholesterol levels. In atherosclerotic lesions, ACAT inh...
Article
We have previously shown, using human T-cell lymphocytotrophic virus-I (HTLV-I)-infected cell lines, that soluble interleukin-6 receptor (sIL-6R) is generated through an alternative splicing mechanism. In this study, we examined human sera for the presence of alternatively spliced soluble IL-6R (AS-sIL-6R). We produced a monoclonal antibody (mAb) r...
Article
Conclusions The real-time processing system of CTSN performs following: A/D conversion; automatic event detection; event data saving; automatic measure of P and S arrivals; event location and print out the calculated results. It is corrected at ny moment by using the off-line system. Since December 1993, this system has been operating normally in t...
Article
By using an ELISA, increased levels of the soluble form (sgp130) of gp130, the IL-6 signal transducer, were detected in the sera of various HTLV-1-associated conditions (HC, ATL, HAM) as compared to normal healthy individuals. Sgp130 levels seemed to be correlated with disease severity. The 94 KD of sgp130 was specifically precipitated in the sera...
Article
A P and S wave velocity model is obtained for the crust in the region along the Longmenshan fault zone, Sichuan Province, China, by using data from a refraction profiling survey carried out in this region and those from local earthquakes. 202 local earthquakes along the fault zone are based on this velocity model, location errors being estimated to...
Article
Since ray paths of direct P and S waves are largely distorted in a magma body, a seismic shadow zone is created. However, scattered or diffracted waves with very small amplitudes can arrive in the shadow zone because their ray paths are different from those of the direct waves. They become the first arrival in the shadow zone. More than 100 seismol...
Article
A polymerase chain reaction (PCR) method was used to detect the interleukin-2 receptor alpha-chain (IL-2R alpha) chain which lacks the conventional transmembrane (TM) domain in mRNA from human T-cell leukaemia virus type-I (HTLV-I)-infected cell lines or peripheral blood mononuclear cells (PBMC) isolated from adult T-cell leukaemia (ATL) patients....
Article
We have developed an inversion method for estimating Q structure by the use of a large number of waveform data from earthquakes. We divide an area to be analyzed into small blocks and simultaneously estimate the Q value in each block, source parameters for each event and site response spectrum for each station. The source spectrum is assumed to be...
Article
All disulfide analogs (types I, II and III) of protegrin (PG)-1, an 18-residue antimicrobial peptide having two intramolecular disulfide bonds, were synthesized using regioselective disulfide bond formation. Random air-oxidation of the fully reduced PG-1 formed the type III PG-1. In addition, a type III analog containing an amidated carboxy-termina...
Article
Full-text available
It is well known that there is a large difference in focal mechanism solutions of events even if they occur within a certain small area. Considering earthquake-generating stress to be uniform in a studied area, we developed a new method for simultaneously determining the stress tensor and the orientation of fault planes for many events by the use o...
Article
Spatial distributions of the depths to the Conrad and the Moho discontinuities show that both discontinuities are deep in the middle of the land area and shallow toward the coastlines. The Pn velocity is as low as ~7.5 km/s beneath the land area, while that beneath the Japan Sea and the Pacific Ocean is 8.0-8.2 km/s. It changes abruptly at the tran...
Article
To detect transcripts encoding the interleukin-6 receptor (IL-6R) molecule lacking the transmembrane (TM) domain, in various cell lines and peripheral blood mononuclear cells (PBMC), we used the polymerase chain reaction (PCR) with primer pairs that flank the TM domain and which were selected to generate a 398-bp fragment. We detected 398-bp and 30...
Article
Full-text available
Seven clinical isolates of Shigella sonnei with reduced susceptibilities to fluoroquinolones (sparfloxacin, ciprofloxacin, and ofloxacin) were obtained. The MICs of fluoroquinolones against these S. sonnei strains were 16 to 32 times higher than those obtained against typical strains that are highly susceptible to these agents. The kinetics of [14C...
Article
Full-text available
Seismic observations with a dense network using telephone telemetries have been done in the eastern part of Yamanashi Prefecture to study the configuration of northern tip of the Philippine Sea plate and the seismotectonics in this area. Hypocenter distributions obtained from this network indicate that most of earthquakes beneath the eastern part o...
Article
The present experiments were designed to study whether GTP binding protein activation and the resulting cAMP plays any role in HIV replication. The results showed that cholera toxin (CT) enhanced HIV replication dose dependently in myelo-monocytic cell lines latently infected with HIV-1, U1 and J22HL-60. Three- to 4-fold enhancement of virus produc...
Article
Possible evidence for deep-seated magmatic activity beneath the northeastern Japan arc has been obtained from micro-earthquake observations. Tomographic inversions for P-wave velocity clearly delineate low-velocity zones, which are inclined to the west and continuously distributed from the uppermost mantle to the upper crust beneath active volcanoe...
Article
Full-text available
The seismic body wave tomography method has been improved and extended to adapt to a general velocity structure with a number of complexity shaped seismic velocity discontinuities and with three-dimensional variations in the velocities in the modeling space. This method is applied to 18,679 arrival times from 470 shallow and intermediate-depth eart...
Article
More than 13,000 arrival times of 562 local shallow earthquakes selected from the Japan University Network Earthquake Catalog are used to investigate the seismic velocity structure of the crust beneath the Japan Islands. We simultaneously determined the hypocenter parameters, P- and S-wave station corrections and depth distributions of the Conrad a...
Article
We determined the minimum inhibitory concentration (MIC) of DR-3355, a newly developed quinolone-derivative antibacterial agent, against clinical isolates of various bacterial species from enteritis patients, and compared them with those of ofloxacin (OFLX), ciprofloxacin (CPFX), nalidixic acid (NA), ampicillin (ABPC), kanamycin (KM). MIC90 of DR-3...
Article
The relationship between type 1 pili-associated adhesion and invasion to HeLa cells by Salmonella braenderup and S. typhimurium was studied. When the clinical isolates of these strains were grown in L-broth, they showed both type 1 pili formation and mannose-sensitive adhesion to HeLa cells. On the other hand, the type 1 pili-defective mutants, whi...
Article
We determined the minimum inhibitory concentrations (MICs) of rokitamycin (TMS-19-Q, RKM), a macrolide antimicrobial agent, against strains of various bacterial species isolated from enteritis patients, and compared them with those of josamycin (JM), erythromycin (EM) and ofloxacin (OFLX). MIC90 of RKM against 147 strains of Campylobacter jejuni, a...
Article
Evidence for possible deep-seated magmatic activity beneath northeastern Japan can be obtained from seismic observations. Tomographic inversions of P-wave velocity data show low-velocity zones distributed in the crust and upper mantle beneath active volcanoes. In or around these zones, anomalously low-frequency micro-earthquakes, perhaps caused by...
Article
In 3-month-old male and female pikas, Ochotona rufescens rufescens, reared at an ambient temperature of 25 degrees C, the mean within-day body temperature was 39.2 degrees C without significant variance. At an ambient temperature of 35 degrees C it increased markedly in males while decreased slightly at 5 degrees C. The pikas showed lower sensitivi...
Article
To know the conditions of contamination by the chemicals in the experimental animal diets, the contents of nitrosodimethylamine (NDMA) were analyzed in the diets for mice and rats. The raw materials of the diets were also analyzed. In addition, NDMA levels were determined in the diets which were stored long or heated in the autoclaves. The averages...
Article
Among 1.041 clinical isolates (77 serovars) of Salmonella which had been derived from cases with acute enterocolitis, 601 (58%) contained one or more plasmids. Large serovar-specific plasmids were seen in 95 of 307 isolates (31%) of Salmonella typhimurium, in 34 of 34 isolates (100%) of Salmonella enteritidis and in 36 of 38 isolates (94.7%) of Sal...
Article
The clinical efficacy, safety and usefulness of Rokitamycin (RKM), a new macrolide antibiotic, were compared with those of Ofloxacin (OFLX) for the treatment of Campylobacter enteritis by a double blind method.The daily dose level of RKM or OFLX was 600 mg. They were orally administered in three divided doses for 5 days.Of 223 cases studied, 106 ca...
Article
Rokitamycin, a newly developed macrolide, was administered to a total of 107 cases, 16 years old or more, in order to evaluate its clinical efficacy, safety and usefulness on Campylobacter enteritis.Daily dosage of 600 mg of rokitamycin was administered orally in three divided doses for 5 days. Bacteriological and clinical efficacies were judged by...
Article
3-D seismic velocity structure of the crust and the uppermost mantle beneath the northeastern Japan Arc is investigated by using arrival time data from local earthquakes. We use a velocity model composed of three layers corresponding to the upper crust, the lower crust and the uppermost mantle, respectively. Taking into account the observed regiona...
Article
The quantity of histamine and the number of mast cells in the skin of the pika were measured and compared with rabbits, guinea pigs and rats. The ranking of regional histamine levels in the skin of the pika was: perianal region greater than abdomen greater than interscapular region = back greater than lumbus greater than head greater than auricle,...
Article
Experimental gastric ulcer formation was performed in the pika and compared with that in the rat. Gastric ulcers were formed in pika that were subjected to water restraint for 4-5 days for 2 hours each day. Gastric ulcers were also formed under conditions of 1-4 days for 3 hours each day and 1-2 days for 5 hours each day. The severest (widest) ulce...
Article
Minimum inhibitory concentrations (MICs) of 7432-S, a newly developed oral cephalosporin, were determined against 136 strains of Shigella spp., 55 of Salmonella spp., 33 of Escherichia coli, 24 of Campylobacter spp., 12 of Vibrio parahaemolyticus and 10 of V. cholerae, and compared with those of cefixime (CFIX), enoxacin (ENX), and nalidixic acid (...
Article
The skin of the pika (Ochotona rufescens rufescens) was found to be remarkably sensitive to the primary irritation of sodium hydroxide, as compared with the skin of the rabbit. After exposure to 0.1 N sodium hydroxide for 24 hr, the pika skin showed severe erosion, ulceration and necrosis as well as crust formation and hyperkeratosis with vascular...
Article
The in-vitro activity of DR-3355, the S-(-)-isomer of ofloxacin, was determined against bacterial pathogens associated with travellers' diarrhoea. DR-3355 was highly active against isolates of enteropathogenic Escherichia coli (MIC90 0.05 mg/l), Salmonella spp. (MIC90 0.10 mg/l), Shigella spp. (MIC90 0.10 mg/l), Campylobacter jejuni (MIC90 0.39 mg/...
Article
We examined 4,739 isolates of Salmonella isolated from patients with gastroenteritis during the period of 1966-1986 in Tokyo for the incidences of serovars, antibiotic resistance and conjugative R plasmids. The period of study was divided into three: 1966-73 (early period), 1974-79 (middle period), and 1980-86 (late period). The predominant serovar...
Article
For the purpose of evaluation of clinical efficacy, safety and usefulness on acute infectious enteritis (bacillary dysentery, and enteritis caued by Salmonella spp., Campylobacter spp., enteropathogenic E. coli, and so on), T-3262, a newly developed pyridone-carboxylic acid derivative, was administered to a total of 136 patients and carriers. In ad...
Article
T-3262 (Tosufloxacin tosilate), a newly developed pyridone-carboxylic acid derivative, was administered to a total of 103 patients and carriers.In addition, in vitro antibacterial activity of T-3262 was determined against the clinical isolates, and compared with those of nalidixic acid (NA), pipemidic acid (PPA), enoxacin (ENX), norfloxacin (NFLX)...
Article
Full-text available
The clinical efficacy, safety and usefulness of lomefloxacin (LFLX, NY-198), a new quinolone antimicrobial agent, were compared with those of pipemidic acid (PPA) in the treatment of infectious enteritis (bacillary dysentery, enteropathogenic Eschericia coli enteritis and Campylobacter enteritis) by a double blind method.Daily dosage of LFLX and PP...
Article
We determined the minimum inhibitory concentrations (MICs) of T-3262, a newly developed quinolone-derived antibacterial agent, against 50 strains of Shigella and 25 strains each of Salmonella, Escherichia coli, Campylobacter and Vibrio parahaemolyticus which had been isolated from enteritis patients and carriers, and compared them with those of oth...
Article
Full-text available
We evaluated the clinical effect and safety of a new quinoline antibacterial agent, NY-198, in patients with acute infectious enteritis (bacillary dysentery, enteropathogenic Escherichia coli enteritis, Campylobacter enteritis, Salmonella enteritis and other bacterial enteritis) and the corresponding carriers (118 subjects in all). NY-198 was orall...
Article
Minimum inhibitory concentrations (MICs) of NY-198, a newly developed quinolone-derivative antibacterial agent, against 99 strains of Shigella, 25 strains each of Salmonella and Escherichia coli, 16 strains of Campylobacter jejuni, and 24 strains of Vibrio (ten strains each of V. parahaemolyticus and V. cholerae and four strains of others), which h...
Article
Minimum inhibitory concentrations (MICs) of NY-198, a newly developed quinolone-derivative antibacterial agent, were determined against 37 strains of Shigella, 30 strains of Salmonella, 8 strains each of Escherichia coli and Campylobacter, 2 strains of Vibrio parahaemolyticus and 1 strain of Aeromonas hydrophila, which had been freshly isolated fro...
Article
Fifty-five cases treated by partial cystectomy (PC) for transitional cell carcinoma of the bladder were analyzed for their prognisis related to tumor grade and stage, and other variables. Demonstrated were (1) apparently no advantage of PC over TUR for low grade (grade 2 or less) and low stage (pT1 or less) tumors, (2) frequent local recurrence sho...
Article
A plasmid containing the transposon gamma delta sequence was immune to further insertion of gamma delta (transposition immunity). Plasmids carrying a fragment containing either 0.2 kilobase pairs of the gamma end or 0.4 kilobase pairs of the delta end of the gamma delta sequence were immune, and other parts of the gamma delta sequence did not confe...
Article
We examined 234 isolates of Salmonella spp. (31 serovars) isolated from patients with gastroenteritis for the presence of plasmids and antimicrobial resistance. Eighty percent or more of S. typhimurium, S. enteritidis and S. braenderup strains carried plasmids. Some of the plasmids were unique to each serovar and their molecular sizes were 90, 54,...
Article
The plasmid pNR333 is a kanamycin-resistant, deletion derivative of pNR113 with an extremely high copy number in Escherichia coli and in Proteus mirabilis. In order to determine the usefulness of pNR333 as a replication gene of vector, the genes encoding chloramphenicol acetyl-transferase (CAT) and beta-galactosidase (beta-gal) were cloned individu...
Article
The effect of norfloxacin (NFLX), a new quinolone agent, was compared with that of pipemidic acid (PPA) on infectious enteritis (bacillary dysentery, Campylobacter enteritis and enteropathogenic E. coli enteritis etc.) by a double-blind method.NFLX was administrated orally in a dose of 600mg/day, and PPA was administrated orally, 2, 000mg/day.The d...
Article
Minimum inhibitory concentrations (MICs) of norfloxacin (NFLX) against 100 strains of Shigella, each 25 strains of Escherichia coli, Salmonella, Campylobacter jejuni, and Vibrio (10 strains of V.parahaemolyticus, 10 strains of V. cholerae and 5 other Vibrio species), which had been isolated from enteritis patients, were measured by agar dilution me...
Article
The clinical effects and safety of a new antibacterial agent, AM-715, was evaluated in patients with acute infectious enteritis (bacillary dysentery, enteropathogenic E. coli enteritis, Campylobacter enteritis, Salmonella enteritis and other bacterial enteritis) and the corresponding carriers (174 subjects in total).AM-715 was orally administered t...
Article
We examined minimal inhibitory concentrations (MICs) of Cefixime (CFIX) against 169 strains of Shigella, 122 strains of Salmonella, 54 strains of Eschenchia coli, and 98 strains of Campylobacter jejuni isolated from patients with diarrhea. MICs of CFIX were higher against Campylobacter jejuni, but remarkably lower against Shigella, Salmonella, and...
Article
The slides from 1, 193 consecutive patients, who underwent simple prostatectomy for presumed benign prostatic hyperplasia were reviewed. Of these, 76 specimens were diagnosised as containing prostatic adenocarcinoma. 1) We divided those lesions into two subgroups, focal lesion and diffuse lesion, depending upon the extent of lesions. The sizes of t...