Sarwo Handayani

Vaccination is one of the methods of preventing SARS-Cov-2 infection. Although the efficacy of several vaccines has been observed, it is unknown how long the antibodies remain in the body. The purpose of this study was to examine the antibody titers in adults, 18 months after receiving two doses of the Astra Zeneca vaccine. This is a cross-sectiona...

Objective To identify circulating HPV types among urban Indonesian women and their specific co-infection patterns in bid to curb HPV infection in the general population and minimize its complications. Methods Urban Indonesian women from general population were selected as sample framework. Sample size and distribution across regions were determine...

Background Hepatitis B is a viral infection that has a high prevalence in Indonesia. The Ministry of Health of Indonesia has conducted a national vaccination program for hepatitis B. In order to evaluate the success of the hepatitis B vaccination in Indonesia, a community study based on basic health research (Riskesdas) was performed nationwide sin...

Hospital is a place with the highest risk of Covid-19 transmission. Healthcare workers should apply safety precautions in order to avoid infection. This study was conducted to obtain information about hospital loci (rooms) that are at risk of transmission of the SARSCov-2 virus. Six hospitals located in DKI Jakarta, East Java, West Java, and North...

Novaria Sari Dewi Panjaitan, Sarwo Handayani, Rita Marleta Dewi Center for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, West Java, IndonesiaCorrespondence: Novaria Sari Dewi Panjaitan, Center for Biomedical Research, Research Organization for Health, National...

Human invasion in the forest domain results in close contact between humans and macaques which may increase the potential transmission of zoonotic diseases, including malaria. Primate-to-human cross-species transmission of infectious agents has become a focus of significant scientific interest over the years. This present study aims to identify mal...

Dengue disease is still a global health problem, according to WHO, which reported cases increased more than eight times over the last two decades. The vector control has been developed, but the dengue fever outbreak cannot be prevented. Meanwhile, there is no dengue antiviral drug until now. Dengue vaccine is one of the potentials to prevent dengue...

Human Papilloma Virus is a major cause of cervical cancer. Recently more than 170 HPV genotypes have been identified. Therefore, the identification of HPV genotype is important for screening, therapy, and management of cervical cancer cases. As part of the national study of cervical cancer in Indonesia, the objective of this study is to identify HP...

Novaria Sari Dewi Panjaitan, Fitriana Fitriana, Sarwo Handayani Center for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center, Cibinong, West Java, IndonesiaCorrespondence: Novaria Sari Dewi Panjaitan, Center for Biomedical Research, Research Organization for Health, Nation...

Host genetic factors, such as the genes for various cytokines and adhesion molecules, play a significant role in determining susceptibility to malaria infection. Polymorphisms in host genes have been correlated with malaria infection in both African and Asian regions. The purpose of this study was to investigate the association between both cytokin...

Background: The World Health Organization reported Indonesia as one of the countries with the most prevalent cases of diphtheria worldwide. The microbiological aspects of diphtheria-inducing bacteria are of great significance in tracing disease transmission and case management. However, clinical aspects are critical for updating clinical features a...

Background: Based on Basic Health Research (RISKESDAS) conducted by Ministry of Health, Indonesia, prediabetes prevalence tends to increase from 2007 until 2018. The numbers are relatively higher in rural than those in urban area despite of small discrepancies between the two (~ 2-4%). The purpose of this study was to identify urban-rural differen...

Primaquine is an effective anti-hypnozoite drug for Plasmodium vivax and Plasmodium ovale. However, it can trigger erythrocyte hemolysis in people with glucose 6-phosphate dehydrogenase (G6PD) deficiency. In a previous report from South Central Timor (SCT), Indonesia, we described the prevalence of Vanua Lava, Chatham, and Viangchan variants; in th...

Children under five years are a vulnerable group for diseases infection, therefore immunity to vaccine preventable diseases are essential, such as diphtheria, pertussis and tetanus. Those mentioned diseases, immunization is the most effective effort to reduce the mortality and morbidity. As a part of Basic Health Research analysis for samples colle...

Gametocytes are a source of malaria transmission, so gametocytes clearance is an important factor especially for falciparum malaria treatment. Since 2010, a combination of dihidroartemisinin-piperaquine(DHP) was applied for malaria treatment in Indonesia. To determine the effect of DHP, we analyzed the factors affecting to gametocytes clearance on...

Positive control of Plasmodium spp. is needed in identification of malaria species using Polymerase Chain Reaction (PCR) method. The limitedness of malaria positive control encourages us to develop the cloning method to multiply Plasmodium spp. DNA particularly P.vivax, P. malariae, and P. ovale that are still unable to be cultured continuously. DN...

A cross sectional study of imunity against rubella was conducted in Surabaya and Tabanan districts with the samples of 343 and 257 on children less than five years old and childbearing age women respectively. Rubella antibody was examined by ELISA method (Enzygnost, Behring). The result showed that approximately 90.6% children less than five years...

This study was a part of the activity of monitoring Dihydroartemisinin-Piperaquine (DHP) treatment in subjects infected with P.falciparum and P.vivax in Kalimantan and Sulawesi. SNP Y976F had been proved as the mutation in pvmdr1 gene which was related to P. vivax resistance chloroquine in Papua. Data of spreading pvmdr1 SNP Y976F outside Papua is...

Maturation of Plasmodium falciparum decreases the deformability of infected red blood cells (RBCs), increasing their clearance as they attempt to pass through endothelial slits of the splenic sinus. Previous studies of Plasmodium vivax-infected RBCsled to opposite conclusions with respect to cellular deformability. To resolve this controversy, P. v...