Santanu Dutta

Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital · DEPARTMENT OF CTVS

Introduction: The likelihood of survival for patients receiving coronary artery bypass surgery with graft surgery is decreased by incomplete myocardial revascularization. The results of doing several grafts to each significant sick artery region are still unknown. They wanted to see how inserting numerous grafts in each myocardial area (supra-compl...

Introduction: Cardiovascular diseases are one of the most prominent health issues of the twenty rst century and the most common cause of death worldwide. Second half of the 20th century has witnessed a global spread of the coronary artery disease (CAD) especially in developing countries, including India. Aims:The aim of the study was to nd out wh...

Delayed Cardiac Perforation by Permanent Pacemaker lead beyond one year of implantation is rare. It is also rarer in passive fixation lead, compared to active fixation lead. There is no Universal consensus regarding management of such cases with percutaneous versus surgical removal of the lead followed by re-implantation. Here we report a case of R...

Buerger's disease or thromboangiitis obliterans is a type of obstructive vascular diseases categorized as vasculitis and usually present in 95% of young smoker men. The main pathogenetic mechanism is interplay between immune system and inflammation. Earlier our phase II study has shown that stempeucel are safe when injected at 2 million cells/kg bo...

Introduction: Cardiac Myxoma is the most common tumour of the heart. It is a benign tumour and is more predominant in the females of 30-60 years. It is very often found in the left atrium and is usually attached to the Inter-atrial septum (IAS). In the present study we aimed to clinically evaluate this disease and understand the various treatment m...

Diaphragmatic hernias of Morgagni are anatomical defects in the anterior diaphragm that allow herniation of abdominal viscera into the thorax. They are the rarest of congenital diaphragmatic hernias and usually present in childhood with respiratory symptomatology. Adults are often asymptomatic or present with strangulation of visceral contents. We...

Introduction: Mediastinum is located in the central part of the chest cavity splitting into the superior, anterior, middle and posterior compartments. They represent a wide diversity of disease states. So, the location and composition of a mass is significant in confining the differential diagnosis. Aims: To study the frequency, location and distri...

This cross-sectional study assessed distribution and pattern of echocardiography confirmed congenital heart disease, among 593 pediatric patients in outpatient departments of a tertiary care hospital in eastern India. Commonest defects were ventricular septal defect (43, 40.7%), atrial septal defect (241, 31.7%), and tetralogy of Fallot (125, 21%).

Abstract: PURPOSE: To evaluate the efficacy and safety of oral tadalafil in reducing pulmonary arterial hypertension (PAH) in adult ostium secundum strial septal defect (OS-ASD) patients. METHODS: Pre-operative patients with OSD complicated with PAH, age >18 years, were enrolled into two groups; Group A (oral tadalafil) and Group B (without tada...

Significance: Critical limb ischemia (CLI) due to Buerger's disease presents a major unmet medical need. The limited therapeutic options lead to increased morbidity and mortality. This study showed that use of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells is safe and efficacious when the cells are injected...

Background: Aspergillus fumigatus is a saprophytic fungus which colonizes in the cavitary lesions in the lungs. In our part of the world, where tuberculosis is endemic, the healed tubercular cavities form a good nidus for this fungus. The fungus forms a fungal ball or aspergilloma within the cavity, which erodes the walls of the cavity and causes h...

Background Hydatid disease is endemic in sheep-raising regions of the world. It is caused by the larval stage of a tapeworm Echinococcus granulosus. The lifecycle of Echinococcus revolves between sheep and dog. Humans get the infection by ingesting the eggs. Lungs are the second most common site of involvement after the liver. We review our 4-year...

Background: Aspergillus fumigatus is a saprophytic fungus which colonizes in the cavitary lesions in the lungs. In our part of the world, where tuberculosis is endemic, the healed tubercular cavities form a good nidus for this fungus. The fungus forms a fungal ball or aspergilloma within the cavity, which erodes the walls of the cavity and causes h...

Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) is associated with intense activation of hemostatic mechanisms. But the precise knowledge of the effects of eliminating CPB in patients undergoing off-pump coronary artery bypass grafting (CABG) are not well established. The present study was carried out to compare and documen...

Background: Rheumatic fever in childhood is the most common cause of Mitral Stenosis in developing countries. The disease is characterized by damaged and deformed mitral valves predisposing them to scarring and narrowing (stenosis) that results in left atrial hypertrophy followed by heart failure. Presently, echocardiography is the main imaging te...

BACKGROUND: Rheumatic Heart Disease (RHD), a chronic acquired heart disorder results from Acute Rheumatic Fever. It is a major public health concern in developing countries. In RHD, mostly the valves get affected. The present study investigated whether extracellular matrix remodelling in rheumatic valve leads to altered levels of collagen metabolis...

Thyroid develops from median rudiment which is a surface elevation dorsal to the tuberculam impar and forms by proliferation of endodermal cells. Lateral thyroid element of the fourth pouch contributes in the development of thyroid gland. Failure of the lateral thyroid element to fuse with the median element may result in a lateral ectopic thyroid...

Objective This study was carried out to evaluate effect of low volume normal frequency ventilation during Cardiopulmonary Bypass (CPB) on immediate postoperative respiratory outcome in patients undergoing elective open heart surgeries. Background Lung deflation during CPB is considered as major cause of postoperative pulmonary dysfunction. Various...

Objectives: The present study is aimed at investigating the involvement of oxidative stress in ischemic heart disease (IHD) of patients in tertiary care hospital in Kolkata.Methods: Serum parameters of myocardial injury, oxidative stress biomarkers and antioxidant enzymes were measured. These data were supported by the data of electrocardiography a...

Murraya koenigii is a popular spice herb in India and South East Asia. The leaves have uses in folk medicine and ayurvedas. Lead is a widely distributed, toxic environment pollutant. Aim of the study is to find therapeutic potentials of aqueous extract of Murraya koenigii (CuLE) against lead induced oxidative damage in cardiac tissue of rats. The o...

Objective: The present studies were aimed at evaluating whether an aqueous extract of Tulsi leaves is capable of ameliorating piroxicam–induced gastric injury in rats. Methods: Male Wister rats were used for the present studies. The aqueous Tulsi leaf extract (TLE) [25, 50, 100 and 200 mg/kg bw] was administered orally to the fasted rats (water ad...

Treatment of rats with lead acetate at a dose of 15 mg / kg body weight intraperitoneally (i.p) for seven consecutive days caused a significant accumulation of lead with concomitant damage in the rat hepatic and renal tissues indicated by the increase in the level of activities of SGPT and serum lactate dehydrogenase 5, levels of blood creatinine a...

Objective: The present study was intended to examine whether administration of aqueous extract of the Curry leaves (Murraya koenigii L.) do possess a protective effect against cadmium-induced oxidative stress in rat liver. Methods: Male albino rats used for present studies were divided in to four groups; control, cadmium treated, aqueous extract pr...

Objectives: The present study is aimed at investigating the involvement of oxidative stress in ischemic heart disease (IHD) of patients in tertiary care hospital in Kolkata.Methods: Serum parameters of myocardial injury, oxidative stress biomarkers and antioxidant enzymes were measured. These data were supported by the data of electrocardiography a...

Objectives: Pleural hydatid is very rare. Pyopneumothorax caused by rupture of pleural hydatid is also very rare. Here we present one such rare case. Study design: Clinical note. Material and methods: A 35 years aged female suffering from pyopneumothorax for one month, was referred to our tertiary referral hospital. USG of right hemithorax, CT scan...

Objectives: Aim of the study is to find therapeutic potentials of aqueous Curry Leaf (Murraya koenigii) Extract (CuLE) against lead induced oxidative damage in hepatic tissue. The objectives are to study the alterations of various stress parameters in lead induced hepatotoxicity and amelioration of the same with CuLE. Methods: Rats were intraperito...

Cardiac myxomas are benign intracavitary neoplasms. Their incidence in cardiac surgery is approximately 0.3%. Biatrial myxomas are extremely rare. A 3 years old child presented with dysphagia, progressive weight loss and repeated attacks of cough and cold with systolic murmur in mitral area. Echocardiography detected biatrial myxoma. Myxomas are kn...

Hydatid cyst is caused by the tapeworm Echinococcus granulosus. It usually involves liver and lungs in humans. Cardiac hydatid cyst is rare, commonly affecting the left ventricle. Here we are reporting a case of Hydatid cyst in the right ventricle without any involvement of liver and lungs which was successfully managed.