s. Vedha Pal Jeyamani

Tamil Nadu Dr. M.G.R. Medical University | TNMGRMU · Department of Allied Health Sciences

In this study a cross sectional survey was conducted in the State of Tamil Nadu to assess the Knowledge, Attitude and Perception of Community Pharmacists on the Professional standards and Responsibilities Entrusted by Pharmacy Practice Regulation-2015. The at most aim in framing and developing of pharmacy practice regulations- 2015 was to develop...

Aim: The aim of the present study was to analyze the cost of Psychiatric drugs in the elderly and to evaluate potentially inappropriate medications (PIMs) in them at the Neurology Outpatient department of a tertiary care hospital using Beers criteria and factors associated with it. Study design: An observational cross-sectional study was carried ou...

Background: Cellulitis, especially of the lower limbs is found to be more common now-a-days in both the sexes. Ascending cellulitis was found to pose both short and long term morbidities. Objective and Methodology: The following study carried out is at the general medicine ward of a government hospital where about 90 patients were taken for study w...

India reported its first cases of COVID 19 in a group of returned Indian medical students from Wuhan to Kerala in January 30, 2020. Tamilnadu reported its first case on March 7, 2020 in Kanchipuram. Disease prognosis worsen when associated with various comorbidities. Understanding the impact of demography and various comorbidities on the disease ou...

Steven Johnson Syndrome (SJS) is an idiosyncratic reaction characterized by severe hypersensitive reactions towards medications, presenting with exfoliative dermatitis, epidermal erythema and blistering. It may or may not be occasionally associated with Toxic Epidermal Necrolysis. Its clinical presentation includes mucocutaneous lesions and fever w...

Cabozantinib (CAB), a Tyrosine Kinase Inhibitor (TKI) is the first-line therapy for Metastatic Renal Cell Carcinoma (mRCC) updated recently. Reports on adverse reactions of CAB include cutaneous reactions in a RCC patient. Other TKI (Sunitinib) reported cases on drug induced acute interstitial nephritis. To illustrate this, we depict a case on CAB...

Rationale: Atherosclerosis is a prominent underlying factor to Diabetes and Hypertension seen in 80% of patients leading to increased formation of thrombus thus blocking blood supply to myocardium. Fibrinolytics, such as streptokinase in the dose of 1,500,000 U in slow IV infusion has good activity for reperfusion. The study is aimed to evaluate th...

S Ethambutol/isoniazid/rifampicin Fulminant hepatitis: case report A 53-year-old man developed fulminant hepatitis during treatment with ethambutol, isoniazid and rifampicin for tuberculosis meningoencephalitis. The man was admitted to hospital with altered sensorium for 1 day, grade IV breathlessness, decreased responsiveness and abdominal distens...

INSILICO docking investigation and molecular properties of phytocompounds in Capsicum annuum on anti lung cancer targets

The prevalence of Anti-Tuberculosis Therapy (ATT) induced liver injury is increased for the past many years with many preexisting factors and conditions like alcohol abuse, persisting liver injury, female gender etc., Studies already mention Isoniazid (INH), Rifampicin (RIF) and Pyrazinamide (PYZ) to report many cases on liver hepatitis/injury. The...

Thyroid carcinoma is the majority widespread endocraine malignancy in that papillary thyroid cancer is a well-differentiated type. Since hyperthyroidism protects from thyroid cancer due to lack of reproduction of thyroid tissue by the thyroid-stimulating hormone. The papillary carcinoma is the fast-growing and metastases to local region rapidly. A...

Disease profile, Crohns Disease, A short description about the disease

Ethyl cellulose, hydroxy propyl methyl cellulose, Methaceylic acid were investigated as a sustained release matrix. Theophylline is used as a model drug for evaluating sustained release drug delivery system. Ethyl cellulose, hydroxyl propyl methyl cellulose, methaceylic acid were used in different concentration i.e. 2%, 3%, 5%, 7.5%, 10% w/w, along...

Background: Irrational practicing of antibiotic prescribing adds up to increased morbidity and mortality of pediatric patients, especially with infections such as pneumonia, meningitis, bronchitis, etc. Objective: To determine the prevalence of irrational usage of antibiotics among pediatric patients and its effect on them. Methods: A cross-section...

ABSTRACT Bullous Pemphigoid is an auto-immune rare disorder occurring both in male and female with more number among females. It comprises of bullae, blisters, lesions formation in the oral mucosa, genital mucosa and other regions where its healing takes a lot of time. The exact etiological cause of Bullous Pemphigoid is not known. More than 70-90%...

Sexual hormones are of essential importance for reproduction and later in life for metabolism, cardiovascular system and general well being of women. Menopause leads to a multiple loss of functions with decrease in estrogen, progesterone levels particularly in regions of brain, bone, skin, connective tissue, peripheral vessels and cardiovascular sy...

Background: Plants have been used as a source of drug for the treatment of Diabetes Mellitus in developing countries where the cost of conventional medicines represents a burden to population. Management of Diabetes Mellitus is a global problem and successful treatment is very essential for preventing or at least delaying the onset of long term com...

Pharmaceutical care including pharmaceutical care plan process (CORE, PRIME and FARM/SOAP) is a systematic method for recording the pharmacist’s examination of patient pharmacotherapy and subsequent modification of medication related problems.

The shaken baby syndrome was once a undefined and challenging case. To detect the proper death cause behind the child’s increased mortality rate caused by abuse occurring in the late of 19’s was really confusing. People of that age blindly believe that shaking the baby while crying will stop them from weeping and induce the baby to sleep. In this r...

ABSTRACT Background: Irrational practicing of antibiotic prescribing add up to increased morbidity and mortality of pediatric patients, especially with infections such as pneumonia, meningitis, bronchitis etc. Objective: To determine the prevalence of irrational usage of antibiotics among pediatric patients and its effect on them. Methods: A cross...

Drug-induced Psoriasis is one among the common etiological factors of Psoriasis reported worldwide. Familiar drugs known to cause psoriasiform eruptions include Anti-malarials, Beta blockers, NSAIDs, Lithium. etc. Certain antihypertensives like ACE inhibitors, diuretics are also documented to have caused psoriatic episodes. A 57 y old South-Indian...

Gastritis is one among the many gastrointestinal conditions commonly found. The etiological cause of gastritis may be of various sources like food habits, toxicity from food etc,. Alcoholic gastritis is where chronic abusers of alcohol face a serious condition with revilement possible only once the withdrawal of alcohol is done. Rehabilitation ther...

Dengue is one of the common mosquito-borne arbovirus infections, especially in India. Dengue virus is a single strand RNA virus, which composed of four serotypes and these serotypes, belongs to the flavivirus genus. Dengue viruses are normally transmitted through the bites of aedes mosquito species. Dengue is the most frequent cause of fever which...

Abstract Steven Johnson syndrome (SJS) is a life-threatening illness usually associated with usage of medicines, which causes drug interactions. SJS seems to be one of the lethal drug reactions. Herbal medications are also responsible for these syndromes; many medications have been reported to cause SJS. Even though only few cases are described in...

Background: Worldwide epidemiological rate of psychiatric disorders has been on an increased count among which Depression stands more common than others. Research under this sector is always a choice of interest which is on progress. Aim: The present study is carried out to study the antidepressant activity with aqueous extract of Rosa centifolia....

Hypersensitivity reactions against non steroidal anti-inflammatory drugs (NSAIDs) like diclofenac can elicit noticeable allergic reactions including systemic anaphylaxis and dermatological lesions. We present a case on diclofenac induced hypersensitivity erythematous Oedematous plaque and urticarial weal positive. No allergic history and no other d...

Health ailments due to occupational disease spawn by exposure to a work place health hazard. It might be due to job environment and exposure intensity. Carpal tunnel syndrome (CTS) is a peripheral compression induced neuropathy results due to median nerve intrigue and at the level of the carpal tunnel, delimitated by the carpal bones and by the tra...

The main objective of the present study was to formulate and evaluate the nanoparticulate drug delivery system for the controlled release of budesonide to control asthma, inflammatory bowel diseases and its associated disease condition. To achieve the above object budesonide nanoparticles were prepared by solvent displacement technique using variou...

Nanoparticles are engineered structures with diameter of <100 nm they are formulated to provide controlled drug release. Polymeric nanoparticles consist of biodegradable polymer, latest development includes natural polymers like Eudragit S100, gelatin, sodium alginate. In this work, polymeric nanoparticles containing antiepileptic drug (AED) - preg...

Objective: The objective of the present study was to formulate and evaluate the nanoparticulate drug delivery system for the controlled release of budesonide to control asthma, inflammatory bowel diseases and its associated disease condition. Materials and Methods: To achieve the above objective, budesonide nanoparticles (NPs) were prepared by solv...

Pemphigus is a group of autoimmune blistering intraepidermal disease of skin and mucosal membranes where there is the acantholysis taking place and gradual binding of autoantibody to antigens on cell surfaces. Drug-induced pemphigus mostly mimics Pemphigus Foliaceus and drugs known to induce are thiol drugs or SH drugs, nonthiolnonphenol drugs, phe...

Diabetes in one among the leading cause of death in the world causing various other secondary complications associated with it. Neuropathy is a foremost primary cause of diabetic ulceration, which reduces sensation at the nerve endings. Diabetic foot ulcer is one of the increasing causes of morbidity and mortality in the present era with uncontroll...

With the increase in number of patients, multiple diseases and complex therapeutic regimen the chances of drug interaction is widening. Poly pharmacy is an unavoidable condition with age, leading to elevated healthcare costs, morbidity and mortality. A prospective observational study was conducted in outpatient department of a tertiary care hospi...

The resistance among innumerable microbial species to various antimicrobial drugs has materialized as a cause of public health hazard all over the world at an alarming rate. Even though the development of multi drug resistant infection is a natural phenomenon, the incongruous use of antimicrobial drugs, inadequate sanitary conditions, irrational u...

Objective: The aim of the present research was formulation and evaluation of anti-inflammatory drug dexibuprofen loaded chitosan-based polymeric nanoparticles (NPs) for the controlled release of dexibuprofen using different concentrations of chitosan and surfactant.

Objective: The objective of the present study was to formulate and evaluate the nanoparticulate drug delivery system for the controlled release of budesonide to control asthma, inflammatory bowel diseases and its associated disease condition.

The resistance among innumerable microbial species to various antimicrobial drugs has materialized as a cause of public health hazard all over the world at an alarming rate. Even though the development of multi drug resistant infection is a natural phenomenon, the incongruous use of antimicrobial drugs, inadequate sanitary conditions, irrational u...

The chances for drug-drug interaction increased with polypharmacy and age, drug-drug interaction have the ability to change the therapeutic effect or the risk of adverse drug reactions. Thus, early detection and recognition of clinically important drug-drug interaction and adverse drug reaction by health care professionals are important.

Aim: The aim of the present study was to analyze the cost of Psychiatric drugs in the elderly and to evaluate potentially inappropriate medications (PIMs) in them at the Neurology Outpatient department of a tertiary care hospital using Beers criteria and factors associated with it. Study design: An observational cross-sectional study was carried ou...

Alcoholic leaf extract of Mucuna pruriens was isolated with different fractions and were subjected to preliminary qualitative chemical investigations. The chloroform fractions showed the presence of glycosides and alkaloids and were subjected to antihyperglycemic activity, antihyperlipidemic activity studies. Acute toxicity was carried out in wiste...

All pharmacists working in a clinical setting whether dispensing medicine or advice require a well-grounded knowledge of drug interactions to prevent harm to patients from medicine combination. The mechanisms by which most interactions develop are well documented and related tom the basic processes by which a drug acts and are acted upon in the bod...

Acute eczema is a chronic, relapsing, inflammatory skin condition characterised by an itchy red rash that favours the skin creases such as the folds of the elbows or behind the knees. Cellulitis can happen when bacteria enter a break in skin and spread. This results in infection, which may cause swelling, redness, pain or warmth. A 60 years old mal...

Introduction: Like all that glitters are not gold, everything white is not always good or angelic.Nutritionists say there are four white poisons salt, refined sugar ,maida and pasteurized milk. White poison poses indeed place a heavy burden on the health care system as it leads to large number of diseases directly attributable to obesity, heart pro...

Erythrodermic psoriasis may ascend from any type of psoriasis and occurs in all age groups. The generalized manifestations of the disease are erythema, edema, desquamation and systemic compromise like fever, dehydration, malaise and malnutrition. Case Presentation: A 70 year old male patient was admitted to the hospital with skin lesions all over t...

Introduction: Acute eczema is a chronic, relapsing, inflammatory skin condition characterized by an itchy red rash that favours the skin creases such as the folds of the elbows or behind the knees. Cellulitis can happen when bacteria enter a break in skin and spread. This results in infection, which may cause swelling, redness, pain or warmth....

With the increase in number of patients, multiple diseases and complex therapeutic regimen the chances of drug interaction is widening. Poly pharmacy is an unavoidable condition with age, leading to elevated healthcare costs, morbidity and mortality. A prospective observational study was conducted in outpatient department of a tertiary care hospita...

Participated in awareness campaign at Perambur Park, Chennai on behalf of Jaya college of Paramedical Sciences for World Pharmacist day, 24.Sep.2017, in association with IPA. Published in Dhinamalar newspaper daily circular, 10.10.2017, Dhinakaran 11.10.2017 Also Published in Pharma Web: newsletter of Tn Pharmaceutical welfare trust: Jul-Aug-Se...

As oral medications are the most preferred route of administration for various physical alignments and there are lots of modified release medications which are formulated for extended release or delayed release of medications, it's a pharmacist role to circulate the information how to use, things which should not be done when the modified release m...

Short Communication

Depression is the disorder of mood rather than disturbances of thought or cognition which ranges from very mild condition, to severe depression accompanied by hallucinations and delusions. A number of drugs are available for the treatment of depression, but clinical evaluation of these drugs has shown incidence of relapses, side effects and drug in...

Ethanolic bark extract of Aegeles mermoles was carried out using soxhlet apparatus. The extract was evaluated for preliminary phytochemical studies, acute toxicity studies and hypoglycemic activity. Acute toxicity study revealed that the ethanolic bark extract even at high dose (2000mg/ kg) produced no death and found to be safe. The hypoglycemic a...

ABSTRACT: Lansoprazole is a proton pump inhibitor used in the management of peptic ulcer. It also has high antimicrobial activity. The main aim of the current study was to improve the therapeutic efficacy and to reduce the side effects of lansoprazole by loading it in nanoparticle drug delivery system. Lansoprazole nanoparticles were prepared by Na...

Pulmonary tuberculosis is a contagious, airborne infection which primarily attacks the lungs, if the therapeutic regimen was not complied it can lead to MDR (Multi drug resistant) condition. The effect of patient counseling can be chart with the episodic improvement which has been documented in the present case. The present case can demonstrate t...

Dengue is the most common mosquito borne viral infection (caused by Dengue type 1, Dengue type 2, Dengue type 3, and Dengue type 4 of the genus Flavivirus and Chikungunya virus) in Chennai, which had an outbreak due to seasonal and monsoon changes. Infection with one of the serotype provides immunity to only that serotype of life, to a person li...

India has a strong history of traditional herbal system of treatment of various health ailments. In spite of substantial advances in medicinal plant research and rapid advances in modern medicine, there was an increasing problem of liver disorders. The aim of the current study was to perform preliminary phytochemical screening, HPTLC finger prin...

Introduction: Diabetes is a chronic disease which require continuous medical care and self-management education to prevent acute and vascular complications, and to reduce the risk of complications and to improve patient quality of life. The prevalence of diabetes and its complications seems to be increasing globally in a higher rate. Materials and...

Women's day was organised in KK college of pharmacy, with prof. Jayashree. M.pharm.Ph.D.. (MMC)as chief guest. Principal Prof A. Meena. M.pharm.Ph.d made a warm note on international womens day. "The idea of this theme is to consider how to build momentum for the effective implementation of the new Sustainable Development Goals, especially goal num...

Organized public awareness Ralley as a community work in Porur to Gerugambakam area for cancer awareness on world cancer day 2015. (Published in Porur times weekly circular)/05.Feb.2015

Ethanolic leaf extract of Erythrina varigata was carried out using soxhlet apparatus. The extract was evaluated for preliminary phytochemical studies, acute toxicity studies and hypoglycemic activity. Acute toxicity study revealed that the ethanolic leaf extract even at high dose (2000mg/ kg) produced no death and found to be safe. The hypoglycemic...

were also carried out. Silyrnarin was used as the standard drug for comparison for hepatoprotective studies. Significant increased in tissue GSH level , free radical scavenging acitivity and decreased lipid peroxidation was observed. The results were comparable with the standard. Administration of 70 % EEBAL (100mg/kg and 200mg/kg) markedly reduced...

The present study deals with formulation of flutamide nanoparticles. Nanoparticles were formulated by emulsification method using ultrasonification and a Cross Linking Technique using different ratios (1:1, 1:2 and 1:3) of drug and polymer ch ltosan. The formulated nanoparticles were characterized by determining its particle size, drug content and...