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IntroductionThe plasma membrane of a cell undergoes continuous deformations and turning-over of its constituents required for a diverse set of functions. And yet, the membrane retains its steady-state surface tension—without which these functions are adversely affected.Objectives In this review, we discuss how the establishment and maintenance of t...
Actomyosin network under the plasma membrane of cells forms a cortical layer that regulates cellular deformations during different processes. What regulates the cortex? Characterized by its thickness, it is believed to be regulated by actin dynamics, filament-length regulators and myosin motor proteins. However, its regulation by cellular morpholog...
Dilated Cardiomyopathy (DCM) is one of the different types of laminopathies caused by the mutations in A-type lamins in somatic cells. The involuntary cyclic stretching of cardiac muscle cells, as observed in normal physiological conditions is perturbed in DCM which afflict patients globally. As A-type lamins are principal components in nuclear mec...
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Question (1)
I want to know the basic fundamental definition of membrane tension and do we have any technique to find out local membrane tension of a particular region of a cell?
