Raoul Schorer

BACKGROUND Arterial hypotension commonly occurs after anesthesia induction and is associated with negative clinical outcomes. Point-of-care ultrasound examination has emerged as a modality to predict postinduction hypotension (PIH). We performed a systematic review and network meta-analysis of the predictive performance of point-of-care ultrasound...

OBJECTIVES The effectiveness of CytoSorb at removing inflammatory mediators in critically ill patients is controversial. DATA SOURCES Electronic databases were searched from inception to May 2023. STUDY SELECTION Randomized controlled trials reporting the effects of CytoSorb therapy on inflammatory parameters in critically ill patients with hyper...

The infusion of glucose-insulin-potassium (GIK) has yielded conflicting results in terms of cardioprotective effects. We conducted a meta-analysis to examine the impact of perioperative GIK infusion in early outcome after cardiac surgery. Randomized controlled trials (RCTs) were eligible if they examined the efficacy of GIK infusion in adults under...

Background Intrapulmonary shunt is a major determinant of oxygenation in thoracic surgery under one-lung ventilation. We reviewed the effects of available treatments on shunt, Pao2/FiO2 and haemodynamics through systematic review and network meta-analysis. Methods Online databases were searched for RCTs comparing pharmacological interventions and...

Patient: Female, 74-year-old Final Diagnosis: Native lung hyperinflation Symptoms: Dyspnea Medication:— Clinical Procedure: — Specialty: Anesthesiology • Pulmonology • Transplantology Objective Unusual clinical course Background Following single-lung transplantation, native lung inflation can progressively develop in patients with emphysema. Cas...

Background Patent foramen ovale (PFO) is associated with perioperative stroke in noncardiac surgery. The magnitude of this association was assessed in a systematic review and meta-analysis. Methods Electronic databases were searched up to June 2022 for studies assessing the association between patent foramen ovale and perioperative stroke in adult...

Background: The effects and safety of extracorporeal hemoadsorption with CytoSorb® in critically ill patients with inflammatory conditions are controversial. Methods: We performed a systematic review with meta-analysis and trial sequential analysis (TSA) of randomized-controlled trials to assess the mortality and safety of CytoSorb® therapy in c...

Smartphones may provide a highly available access to simplified hypertension screening in environments with limited health care resources. Most studies involving smartphone blood pressure (BP) apps have focused on validation in static conditions without taking into account intraindividual BP variations. We report here the first experimental evidenc...

Background Myocardial injury after noncardiac surgery frequently occurs and may influence survival. The aims of this study were to examine the association between myocardial injury after noncardiac surgery and patient and procedural factors as well as its impact on postoperative clinical outcome. Methods A retrospective analysis was conducted from...

Perioperative fluid balance has a major impact on clinical and functional outcome, regardless of the type of interventions. In thoracic surgery, patients are more vulnerable to intravenous fluid overload and to develop acute respiratory distress syndrome and other complications. New insight has been gained on the mechanisms causing pulmonary compli...

The “moderate-to-high-risk” surgical patient is typically older, frail, malnourished, suffering from multiple comorbidities and presenting with unhealthy life style such as smoking, hazardous drinking and sedentarity. Poor aerobic fitness, sarcopenia and “toxic” behaviors are modifiable risk factors for major postoperative complications. The physio...

More than 70 years after its original report, the hypoxic pulmonary vasoconstriction (HPV) response continues to spark scientific interest on its mechanisms and clinical implications, particularly for anesthesiologists involved in thoracic surgery. Selective airway intubation and one-lung ventilation (OLV) facilitates the surgical intervention on a...

Objective Hypertension is a preventable disease but only half of the affected population is aware of it. Digital health approaches, in particular mobile health diagnostics, have been shown to be effective and scalable for chronic disease detection and management. Smartphones are widely available and have the potential to be used as a “cuffless” blo...

Background The aim of this study was to compare the occurrence of postoperative complications in patients undergoing elective open abdominal surgery and receiving intraoperative goal-directed hemodynamic therapy or restrictive normovolemic therapy. Methods A total of 401 patients were randomized in the goal-directed hemodynamic therapy or restrict...

Abstract Mobile health diagnostics have been shown to be effective and scalable for chronic disease detection and management. By maximizing the smartphones’ optics and computational power, they could allow assessment of physiological information from the morphology of pulse waves and thus estimate cuffless blood pressure (BP). We trained the parame...

Rationale: Preoperative poor physical fitness and respiratory muscle weakness are associated with postoperative pulmonary complications that result in prolonged hospital length of stay and increased mortality. Objectives: Examine the effect of preoperative exercise training on the risk of postoperative pulmonary complications across different su...

Introduction Although experimental studies strongly support the cardioprotective effects of glucose—insulin—potassium (GIK) infusion, clinical trials have yielded mixed results due to the heterogeneity of patient populations as well as varying GIK administration patterns. An updated systematic review and meta-analysis were conducted to assess the i...

What we already know about this topic: Among patients with sepsis or septic shock, a variety of extracorporeal blood purification techniques are availableIndividual existing trials evaluating these options are underpowered to provide clear evidence WHAT THIS PAPER TELLS US THAT IS NEW: Meta-analysis of very low-quality randomized controlled trial...

An ongoing issue in vascular medicine is the measure of the blood flow. Catheterization remains the gold standard measurement method, although non-invasive techniques are an area of intense research. We hereby present a computational method for real-time measurement of the blood flow from color flow Doppler data, with a focus on simplicity and moni...

Background: Impairment in aerobic fitness is a potential modifiable risk factor for postoperative complications. In this randomized controlled trial, we hypothesized that a high-intensity interval training (HIIT) program enhances cardiorespiratory fitness before lung cancer surgery and therefore reduces the risk of postoperative complications. Me...