Rajiu Venkatesan

Bharathidasan University | bdu · Centre for Nanoscience and Nanotechnology

Diluted magnetic semiconductors (DMS), fractionally doped by magnetic ions, are peculiar, and a single semiconductor effectively contributes to charge and spin properties for various applications, including data and energy storage. Here, a low temperature assisted co-precipitation method produced a series of Co doped ZnO nanoparticles. After struct...

The high-ordered crystal structure of a thermoelectric material does not delimit the phonon conductivity but shows improved electrical properties. Disordered crystal structures act as scattering centers for phonon, but at the expense of the electrical properties of the material. Hence, a diminished thermal (phonon) conductivity and improved electro...

The acute lung injury (ALI) is an inflammatory disorder associated with cytokine storm, which activates various reactive oxygen species (ROS) signaling pathways and causes severe complications in patients as currently seen in coronavirus disease 2019 (COVID-19). There is an urgent need for medication of the inflammatory lung environment and effecti...

The chronic autoimmune of rheumatoid arthritis (RA) usually results in inflammation of synovial joint, leading to pain, and destruction of cartilage and bone. Activated macrophages (M1 macrophages) actively take part in the RA pathogenesis, intensifying the inflammation and destruction of bone and cartilage. In this study, a nanoplatform was develo...

In recent years, the development of a nano-conjugate system for drug delivery applications has gained attention among researchers. Keeping this in mind, in this study, we developed a doxorubicin–platinum conjugate system that targeted breast cancer cell lines. To achieve this, we developed platinum nanoparticles using polyvinylpyrrolidone (PVP). Hi...

Herein, we report facile theranostic platinum nanoparticles (PtNPs) conjugated to an anticancer drug, doxorubicin (DOX), in unraveling the inhibition of a cell survival PI3K/AKT (phosphatidylinositol 3-kinase/protein kinase B) signaling pathway in MCF-7 and MDA-MB-231 human breast cancer cells. The significant features of our [email protected] as a...

Herein, we report the one-pot synthesis of WO3/RGO composite and its efficient electrochemical activity in catechol (CC) oxidation. Anchoring of 1-D WO3 microrods on 2-D RGO nanosheets were confirmed through the detailed physicochemical analyses (XRD, FESEM, XPS, Raman). Availability of large electrocatalytically active surface area yields the cond...

Herein, we report the one-pot synthesis of WO3/RGO composite and its efficient electrochemical activity in catechol (CC) oxidation. Anchoring of 1-D WO3 microrods on 2-D RGO nanosheets were confirmed through the detailed physicochemical analyses (XRD, FESEM, XPS, Raman). Availability of large electrocatalytically active surface area yields the cond...

Aspects of inorganic medicinal chemistry aim at developing metal coordinated complexes that are efficient therapeutic agents for cancer. However, intrinsic toxicity of these complexes impedes their effective clinical use. In order to reduce the toxicity and improve the pharmacokinetics and biodistribution, we developed a nanovector candidate and en...

The importance of inflammatory tissue microenvironment on the repair and regeneration of tissues and organs has been well recognized. In particular, the phenotypes of macrophages can significantly influence on the processes of tissue repair and remodeling. Among the many types of biomaterials, the particles in the range from nanometers to submicron...

Catechol, an essential industrial feedstock is one of the major environmental pollutant which causes several health issues including skin irritation, eye damage and genetic defects. In this work, we have investigated the catechol sensing performance of ZnO/RGO composites for its quantitative detection. ZnO/RGO composite showed superior electron tra...

Herein, different polymorphs (α, β, γ and δ) of MnO2 have been synthesized and its electrochemical sensing behaviour was scrutinized with glucose as a probe molecule. Comparative morphology and structural features of all the polymorphs of MnO2 were investigated through Field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), mi...

Recent advances in nanotechnology have revolutionized nanomedicine to concurrently deliver multiple drugs for combination chemotherapy. Despite some improvements in drug delivery system, the accommodation of combination chemotherapeutics in hybrid nanostructure with tunable chemistry remains a challenge. Here, we have made a hypothesis and designed...

Curcumin (Curcuma longa L), a yellow-colored Indian spice, receives immense attention for the prevention and treatment of various cancers. Despite the superlative therapeutic efficacy, its poor solubility and instability in the aqueous medium hinder the effectiveness of cancer treatment. The novel preparation of curcumin nanoparticles by mechanical...

Theranostic nanoparticles with multifunctional ability have been emerging as a new platform for biomedical applications such as imaging, sensing and drug delivery. Despite gold nanorods (Au NRs) being an excellent nanosource with multifunctional versatility, they have certain limitations in biomedical applications, which include surfactant toxicity...