Per Morberg

Umeå University | UMU · Department of Surgical and Perioperative Sciences

Background: Venous thromboembolic events (VTE) are well-known and serious complications following a trauma to the lower extremities. There is an ongoing debate on the benefit of low molecular weight heparin (LMWH) as prophylaxis following ankle fracture treatment. We examined the association between the incidence of VTE and the use of LMWH-prophyla...

Background The purpose of this study was to compare the cumulative incidence of postoperative periprosthetic fracture (PPF) in a cohort of femoral neck fracture (FNF) patients treated with two commonly used cemented stems: either a collarless, polished, tapered Exeter stem or the anatomic Lubinus SP2 stem. Methods In this retrospective multicenter...

Objectives - We aimed to investigate how pre-bending affects the mechanical properties, specifically fatigue, of stainless-steel plates. Methods - 3.5mm LCP 10-hole plates were pre-bent in 1, 2 and 3 locations to the same overall degree and fatigue testing performed. Finite Element Analysis (FEA) was performed in Strand7 (version 2.4.6) to better...

Introduction: The literature regarding undisplaced femoral neck fractures (FNF) is sparse. The aim of this prospective feasibility study is to compare the clinical outcome after undisplaced FNF treated with internal fixation (IF) and displaced FNF treated with hip arthroplasty. We hypothesized that hip arthroplasty would give a lower incidence of...

Background: What is the right surface for an implant to achieve biological fixation? Surface technologies can play important roles in encouraging interactions between the implant surface and the host bone to achieve osseointegration. Preclinical animal models provide important insight into in vivo performance related to bone ongrowth and implant f...

Background What is the right surface for an implant to achieve biological fixation? Surface technologies can play important roles in encouraging interactions between the implant surface and the host bone to achieve osseointegration. Pre-clinical animal models provide important insight into in-vivo performance related to bone ongrowth and implant fi...

Background What is the right surface for an implant to achieve biological fixation? Surface technologies can play important roles in encouraging interactions between the implant surface and the host bone to achieve osseointegration. Pre-clinical animal models provide important insight into in-vivo performance related to bone ongrowth and implant fi...

Background context: The potential for osseointegration to provide biological fixation for implants may be related to anatomical site and loading conditions. Purpose: To evaluate the influence of anatomical site on osseointegration of 3D-printed implants. Study design: A comparative preclinical study was performed evaluating bone ingrowth in co...

Background The ankle fracture is one of the most common fractures, increasing in an ageing population, but not generally seen as an osteoporotic fracture. The aim of this study was to examine the relationship between different AO/OTA classes of ankle fractures, age, sex and type of trauma. Methods Ankle fractures, treated at any of the hospitals i...

Background The Swedish Fracture Register (SFR) currently contains information on more than 190,000 fractures. Patient Reported Outcome Measures (PROMs) are used for monitoring functional results after fracture treatment. One weakness, as in many surveys, is a low response rate. The aim of the current study was to examine if non-responders of a surv...

Background and purpose — Displaced femoral neck fractures (FNFs) are associated with high rates of mortality during the first postoperative year. The Sernbo score (based on age, habitat, mobility, and mental state) can be used to stratify patients into groups with different 1-year mortality. We assessed this predictive ability in patients with a di...

Introduction: Since 2011 the Swedish Fracture Register (SFR) has collected information on fracture epidemiology, treatment and outcome. More than 112 000 fractures, including 11 600 ankle fractures, have been registered so far. The accuracy of the classification is crucial when using the register in future research and quality improvement of care....

Uncemented joint replacement with a variety of substrate materials, structures, and coatings are commonplace in arthroplasty. Even with specialized surgical preparation of bone, intimate contact between the implant and host bone may not always be achieved. This study evaluated the in vivo effect of fibrillar atelopeptide and PEG crosslinked collage...

Wear of the polyethylene (PE) insert in total knee arthroplasty remains a significant problem. The generation of biologically active wear particles may ultimately affect implant longevity through osteolysis or premature/catastrophic PE failure. The rate and pattern of wear is influenced by many factors, including component geometry and individual l...

Calcium sulfate, plaster of Paris, has a long clinical history for use as a bone graft substitute in various skeletal sites. The current authors examined the in vivo response of calcium sulfate pellets alone or in combination with autogenous bone graft in a bilateral critical-size distal femoral cancellous defect in an adult sheep model. New thick...

Knee kinematics after total knee arthroplasty is dictated primarily by implant geometry and native soft tissue constraints. This study highlights the importance of a functioning posterior cruciate ligament in limiting excessive anteroposterior translation in a mobile bearing knee design that relies on native posterior cruciate ligament integrity an...

This study examined the role of substrate preparation and hydroxyapatite (HA) coating thickness on bone ongrowth and shear strength in a bilateral bicortical sheep model. Plasma-sprayed and grit-blasted titanium implants with different thickness HA coatings were examined at 4, 8, 12, and 26 weeks after implantation. Shear strength increased with ti...

The strain distribution imposed on a femur following a total joint replacement is an important factor, in proximal bone loss due to stress shielding, and long term clinical success. This study investigated how five different design parameters of a cementless titanium femoral prosthesis influenced cortical strains. Test loads were applied and strain...

We used vital staining with tetracycline to detect viability of bone at the bone-cement interface in 11 stable ICLH femoral surface replacement prostheses that were retrieved at revision surgery for acetabular loosening. The resected femoral heads were processed for undecalcified ground sections with the prostheses in situ. All sections showed dire...

Purpose: This study was an investigation to determine whether human growth hormone (hGH) continuously administered to rabbits may improve implant integration in bone. Materials and methods: Thirty-two commercially pure titanium (c.p. Ti) implants were inserted in the tibiae of 16 rabbits. Human growth hormone (0.3 U/kg/d) or sodium chloride (NaC...

Achieving a stable bone-implant interface is an important factor in the long-term outcome of joint arthroplasty. In this study, we employed an ovine bicortical model to compare the bone-healing response to five different surfaces on titanium alloy implants: grit blasted (GB), grit blasted plus hydroxyapatite (50 microm thick) coating (GBHA), Poroco...

We compared analgesic effects and pharmacokinetics of intraarticular versus intravenous administration of morphine after arthroscopic anterior cruciate ligament surgery. In a double-blind placebo-controlled study, 40 patients were randomly allocated to one of four treatment groups. Group I received 1 mg morphine intraarticularly and saline intraven...

A computerised, real time, thin-film pressure transducer method is used to measure tibiofemoral contact area in total knee arthroplasty (TKA) devices that is easier and more reliable and reproducible as compared to the Fuji pressure-sensitive film technique. Many authors have suggested that contact areas and pressures within TKA devices can be a pr...

Both tibial marrow cavities of 12 rabbits were evacuated and filled with curing bone cement. In one of the tibias conventional curing bone cement (Simplex P) was injected, while the other tibia of the same animal was filled with a low temperature curing bone cement (Boneloc). Three titanium implants were inserted along the proximal metaphysis of ea...

Although Achilles tendon injuries are common overuse injuries in sports, the exact incidence is unknown, primarily as a result of varying definitions and diagnoses of the underlying pathological changes. Despite numerous studies of treatment of the Achilles tendon injuries, the long-term results are not well known. The results after surgical treatm...

We diagnosed entrapment of the superficial peroneal nerve in 17 patients (19 legs) with a mean age of 41 years. In all cases, plain radiographs of the leg, nerve-conduction studies of the superficial peroneal nerve and measurement of the intramuscular pressure at rest after exercise were normal. Diagnostic tests for nerve compression during rest af...

Several recent studies have investigated the effects of growth hormone (GH) on the healing of fractures and bone ingrowth, but with conflicting results. The negative results may be due to antibody formation against injected GH or because some experimental models are able to prove only positive GH effects. In this study, we wanted to investigate the...

We diagnosed entrapment of the superficial peroneal nerve in 17 patients (19 legs) with a mean age of 41 years. In all cases, plain radiographs of the leg, nerve-conduction studies of the superficial peroneal nerve and measurement of the intramuscular pressure at rest after exercise were normal. Diagnostic tests for nerve compression during rest af...

Ten commercially pure titanium implants were inserted in the tibia of ten mature New Zealand white rabbits for a healing period of 3 months. Cut and ground sections were performed on transversely and longitudinally cut tibia bone with implants in situ. Each implant with surrounding bone was processed by (a) dividing it into two parts by cutting tra...

Titanium implants were inserted in transgenic mice overexpressing bovine growth hormone. Four weeks after insertion the implants were cut out en bloc with the surrounding bone. The undecalcified specimens were cut and ground to a thickness of approximately 10 m. Histomorphometry demonstrated significantly more direct bone to metal contact for the t...

Ten screw-shaped commercially pure titanium implants were inserted in 10 rabbit tibia. The implants with surrounding bone were harvested after 12 weeks. The samples were processed to be cut and ground. Histomorphometrical analyses of the bone-to-metal contact and the bone area around the entire implants were performed on transvertically cut section...

Tissue reactions and percentage of mineralized bone in three different types of retrieved femoral head hip resurface prostheses were studied in undecalcified ground sections without removing the metal. All of the prostheses demonstrated soft tissue between the cement-implant and bone. There were some areas without soft tissue between bone and cemen...

Screw implants of c.p. titanium and polymerized methylmethacrylate (PMMA) were inserted in the rabbit tibia. The animals were sacrificed after 5 weeks and 9 months, respectively. In all sections a soft tissue membrane was observed around the PMMA implants and numerous macrophages and many giant cells were observed at the interface. The titanium imp...

The bone healing capacity after filling the medullary cavity with bone cement, was investigated using the bone harvest chamber. With this technique it is possible to repeatedly harvest newly formed cortical bone inside the chamber for, in principle, indefinite times of follow-up. In the short-term follow-up, 3–11 weeks after cement insertion, there...

Screw-shaped implants of commercially pure titanium and polymerized methyl methacrylate were inserted into the rabbit tibia. The animals were divided into two groups, and the implants were unscrewed after 5 weeks and 9 months, respectively. After both intervals, removal torque was greatest for the titanium implants. This difference was probably due...

We describe a titanium implant for repeated intramedullary pressure measurements. The implant has been inserted permanently in the tibia of rabbits. Pressure is transmitted through a membrane in the chamber to a transducer connected to a meter. During the recordings no penetration of the cortex is necessary. The measured intact intramedullary press...