Neomal De Silva

The National Hospital of Sri Lanka · Department of Endocrinology

Purpose Vitamin D deficiency/insufficiency may increase the susceptibility to COVID-19. We aimed to determine the association between vitamin D deficiency/insufficiency and susceptibility to COVID-19, its severity, mortality and role of vitamin D in its treatment. Methods We searched CINHAL, Cochrane library, EMBASE, PubMED, Scopus, and Web of Sci...

Background Screening for undiagnosed diabetes is not widely undertaken due to the high costs and invasiveness of blood sampling. Simple non-invasive tools to identify high risk individuals can facilitate screening. The main objectives of this study are to develop and validate a risk score for screening undiagnosed diabetes among Sri Lankan adults a...

Background: Pseudohypoparathyroidism(PHP) is a heterogeneous group of disorders due to impaired activation of c AMP dependant pathways following binding of parathyroid hormone (PTH) to its receptor. In PHP end organ resistance to PTH results in hypocalcaemia, hyperphosphataemia and high PTH levels. Case presentation: A 59 year old male presented...

We present a 62-year-old patient who presented with polyuria, loss of appetite, malaise and vomiting. He was found to have PTH independent hypercalcaemia and vitamin D insufficiency. Extensive evaluation for solid organ or haematological malignancy including contrast enhanced CT chest, abdomen, pelvis, serum protein electrophoresis, bence jones pro...

BACKGROUND: Dyslipidemia is a major risk factor for cardiovascular disease. Prevalence patterns and determinants of dyslipidemia in Sri Lanka are unkown. OBJECTIVES: We aimed to determine the prevalence and correlates of dyslipidemia among Sri Lan-kan adults. METHODS: A nationally representative sample was recruited by multistage random cluster sam...

A 48-year-old patient with a history of diabetes mellitus, presented to a surgical ward with abdominal pain. She was found to have hypokalemia. Her younger sister had passed away due to sudden cardiac death at the age of 25years. Further evaluation revealed an elevated trans-tubular potassium gradient suggestive of renal potassium loss, normal bloo...

Long-term use of exogenous glucocorticoids leads to the suppression of the hypothalamic–pituitary–adrenal axis. Therefore, if the glucocorticoid is withdrawn abruptly, patients will develop adrenal insufficiency. Hypercalcaemia is a rare but well-known complication of adrenal insufficiency. However, hypercalcaemia is a rare presentation of glucocor...

Background: Postmenopausal hirsutism could be due to a myriad of causes, including ovarian and adrenal tumours, ovarian hyperthecosis, exogenous androgens, and Cushing's syndrome. We report a patient who was found to have a rare cause of postmenopausal hirsutism. Case Presentation. A 64-year-old postmenopausal woman with a history of hypertension,...

Background : Miller Fisher Syndrome usually presents with complete ophthalmoplegia, areflexia and ataxia. We present an unusual case which presented with unilateral abducens nerve palsy. Case presentation : A 51 year old female patient presented with a history of difficulty in walking and double vision for 1 week which started 2 weeks following an...

Background Dyslipidaemia is a major risk factor for CVD. Prevalence patterns and determinants of dyslipidemia in Sri Lanka are unkown. Objectives We aimed to determine the prevalence and correlates of dyslipidaemia among Sri Lankan adults. Methods Nationally representative sample was recruited by multi-stage random cluster sampling in Sri Lanka D...