Natalia Lesiewska

Nicolaus Copernicus University | umk · Department of Clinical Neuropsychology

Objectives: It has been belived that changes in diastolic blood velocities in the fetal ductus venosus were due to increased central venous pressure secondary to increased fetal heart strain during hypoxia or heart failure. There have been recent reports of changes in ductus venosus blood velocity without signs of increased fetal heart strain. The...

Background: The role of executive functions (EF) is to maintain particular behaviours in order to achieve intended goals. EF are crucial in management of pre-diabetes, diabetes and obesity which are grievous diseases and can lead to severe complications. The aims of our study were to: assess EF in group of obese subject with carbohydrate disorders...

Purpose Affective temperament shows innate predisposition to affective disorders and has been studied in patients with type 2 diabetes mellitus (T2DM) and obesity. Studies describing connections between depressive disorders, obesity and T2DM, show a bidirectional way in which these disorders affect each other. Given that obesity, depression, and T2...

Aim The aim of this review is to analyze current evidence about how pregnancy and pathologies which occur during pregnancy may affect the function of woman's brain, and how those changes may influence cognitive functioning. Background During pregnancy occur adaptive changes in woman's body which are necessary for proper fetal development. Pregn...

Background: Obesity is a chronic condition associated with poorer cognitive functioning. Wisconsin Card Sorting Test (WCST) is a useful tool for evaluating executive functions. In this study, we assessed the association between dopaminergic gene polymorphisms: DAT1 (SLC6A3), COMTVal158Met, DRD4 (48-bp variable number of tandem repeats - VNTR) and...

Studies indicate the heritable nature of affective temperament, which shows personality traits predisposing to the development of mental disorders. Dopaminergic gene polymorphisms such as DRD4, COMTVal158Met, and DAT1 have been linked to affective disorders in obesity. Due to possible correlation between the aforementioned polymorphisms and the aff...

Background Patients with obesity experience many psychological burdens. Some of them result directly from the load that jets excessive weight. Nevertheless, it seems that the susceptibility of obese people to accompanying mental disorders can be ingested not only by the environment, but also genetically. The aim of this work was to determine the co...

Background Temperament is a group of inherited personality traits that emerge in the early stages of human life. Such temperament is the basis of personality formation. The Hagop Akiskal, based on the theorems of Kraepelin and Kretschmer, established the existence of five types of affective temperament: depressive, hyperthymic, cyclothymic, irritab...

Psychiatric disorders are significantly common complications among patients suffering from inflammatory bowel diseases (IBD). Affective temperament is a concept of core personality traits, which can decribe the vulnerability to mood disorders, therefore its evaluation might convey useful information about patients' mental status in autoimmune disor...

gastro TEMPS_3 anonim_Eng.xlsx. Data base of affective temperament in IBD patients. (XLSX)

gastro baza_12 anonim_ENG.xlsx. Data base of clinical factors and surgical treatment of IBD patients. (XLSX)

ABSTRACT Neurothrophins are crucial in the regulation of many processes, such as nerve cells development and neuroplasticity and brain-derived neurothrophic factor (BDNF) is the major one. Researchers still scrutinize the role of BDNF Val66Met polymorphism in eating disorders and cognition, however, literature present inconsistent findings regardin...

ABSTRACT Introduction. This study was conducted on a population of patients with inflammatory bowel disease (IBD) and was based on an assessment of the prevalence and severity of depression and anxiety symptoms in various clinical aspects. The psychological features of IBD patients are very important in the perception of symptoms, but crucial as tr...

Objectives Depressive symptoms are common among patients with obesity. Abnormalities in dopamine signaling involved in the reward circuit may ensue excessive consumption of food, resulting in obesity and leading to neuropsychiatric disorders such as depression. This study sought to investigate the association of polymorphisms in the genes encoding...

Many studies show high prevalence of affective disorders in obese patients. Affective temperament is a subclinical manifestation of such conditions. The 5-HTT gene encoding the serotonin transporter may be involved in both mood and eating dysregulation. The aim of this study was to investigate the influence of a polymorphism in the 5-HTT gene on af...