Mohsen Arbabi

Kashan University of Medical Sciences and Health Services · Department of Medical Laboratory

Introduction: Recent studies have proposed various COVID-19 vaccines to control the disease and protect susceptible individuals. However, immunogenicity and safety of COVID-19 vaccines in various populations are not well identified yet. Therefore, this study aimed to elucidate the efficacy and safety of the BBIBP-CorV (Sinopharm) and ChAdOx1 nCoV-1...

Therapeutic research is very important in the prevention and treatment of leishmaniasis due to problems such as drug resistance, scarring and disease recurrence. The aim of this study was to determine how Leishmania major responds to the anti-leishmaniasis properties of podophyllotoxin and podophyllin. Cultured Leishmania promastigotes were exposed...

Malaria is the most common cause of fever in travellers returning from malaria-endemic areas. Imported malaria can hinder the progress of elimination programs. In the present study, we describe an imported malaria case in a 45-year-old Iranian man from Ivory Coast who had returned to Iran after taking annual leave. He was hospitalized in Kamkar-Ara...

Objectives: Endolimax is a protozoan genus belongs to Amoebida order. The member of this genus occurrence in a vast range of vertebrate and invertebrate, but the species of this genus are not well studied. This review aimed to provide an updated list and some summarized information on Endolimax species, which were identified in human and animals up...

Introduction: Trichostrongyloiasis is a prevalent infection in humans and some animals worldwide. Morphology is a reliable tool for identifying Trichostrongylus species. This study aimed to determine the prevalence of Trichostrongylus infection in livestock and compare the morphometric characteristics of the species in sheep and goats referred to K...

Background: Dicrocoeliasis and fascioliasis are foodborne parasitic diseases of the biliary tract, resulting from Dicrocoelium dendriticum and Fasciola hepatica causing extensive financial losses and serious health problems in ruminants. Due to low-performance medications, drug delivery is a tremendous project to improve interventions available for...

Fentanyl is a potent narcotic drug with the same effects as morphine or heroin, but it’s significantly more potent than these drugs. That means a tiny dose can have a dangerous impact and is also lethal, so it is essential to measure it. In this work, we have developed a new electrochemical sensor to measure this deadly drug utilizing a nanocomposi...

Objective: Hepatocellular carcinoma (HCC) as a chronic liver condition is largely associated with immune responses. Previous studies have revealed that different subsets of lymphocytes play fundamental roles in controlling or improving the development and outcome of solid tumors like HCC. Hence, this study aimed to investigate whether immune system...

Aim: Despite the various studies done in the field of cutaneous leishmaniasis treatment, there is still no perfect and safe drug for definite treatment of this disease. Therefore, the quest to find an appropriate drug continues. Previous studies have shown that auranofin has anti-leishmanial activity; therefore, in this study; the effect of auranof...

Aims: In vitro cultivation of digenea would help the development of effective treatments and studies of the biology of the parasites. The goal of the present study was to optimize culture conditions for the maintenance liver fluke, Dicrocoelium dendriticum. Materials and Methods: Forty fresh D. dendriticum were collected from the sheep liver and wa...

Background: Dicrocoeliasis is a rare Food-Born parasitic disease of the grazing herbivores as well humans, caused by Dicrocoelium dendriticum making severe pathological changes of the liver and bile systems, and therapeutic options for treatment are limited. With the appearance of drug resistance in liver flukes, there is a need to focus on alterna...

Original ArticleAims: Blastocystis species are one of the most common enteric protist infections in humans and some animals worldwide. Molecular studies have shown that there is a high level of genetic variation among Blastocystis isolates. The aim of this study was to identify the subtypes and frequency of Blastocystis isolates in patients who ref...

OriginaAims: The control of fascioliasis has depended on the utilization of a predetermined number of anthelmintic drugs. Nonetheless, the resistance of antifasciolid is presently boundless, and there is a need for potential drug properties of medicinal plants as new medications against Fasciola spp. to interrupt the parasite transmission. Material...

Aims: Hydatidosis is an important zoonotic disease that is caused by a tiny tapeworm, namely Echinococcus granulosus. In this study, three polymerase chain reaction (PCR)-based methods, including, high resolution melting (HRM) analysis, DNA sequencing, and PCR-restriction fragment length polymorphism (RFLP) have been used for genotype the identific...

Aim: Cattle is one of the main sources of food supply chain for humans in most countries. The present study aimed to identify the infection rates for Toxoplasma gondii, Neospora caninum, and Sarcocystis spp. by polymerase chain reaction (PCR) method in native slaughtered cattle in Kashan, central Iran. Materials and Methods: Totally, 159 diaphragm,...

Present strategy introduces a novel method established for the synthesis of spherical shape ErVO4/MnWO4 heterostructures by a sonochemical method. This heterostructures with optima morphology can be synthesized by changing power and time ultrasound irradiation without any capping agent. BET analysis revealed that ErVO4/MnWO4 prepared in the presenc...

The article's abstract is no available.

Purpose In the current era, cystic echinococcosis (CE), as larval stage of Echinococcus granulosus, is considered as a threat to human health. Scolicidal agents used in the surgery of cysts have different side effects. Therefore, the present study aimed to assess the effects of chitosan nanoparticles containing curcumin (Ch–Cu NPs) on the protoscol...

BACKGROUND: Dicrocoeliasis is one of the commonest parasitic diseases of the bile ducts and gallbladder in a wide range of mammals including ruminants and sometimes human being. The disease is really important in medicine, economy, and veterinary medicine. Annually, slaughter house loses a huge amount because of losing a great deal of valuable prot...

Background and Aims: The aim of this study is to clarify nitric oxide (NO)-production by spleen and the importance of spleen in malaria infection in murine model. Materials and Methods: Thirty outbred NMRI female mice were divided into four groups, Group I: No intervention (Healthy control), Group II: With splenectomy (Healthy test), Group III: No...

Giardiasis has a global distribution and it is a common cause of diarrhea in both children and adults and is transmitted via the fecal-oral route through direct or indirect ingestion of cysts. The laboratory diagnosis of Giardia spp. is mainly based on demonstration of microscopic cyst or trophozoite in stool samples but several immunological-based...

Recurrence of hydatidosis may results from cyst fluid spillage during surgery. To inactivate the cyst content, different scolicidal agents have been introduced. Nevertheless, novel and more effective treatments are needed due to the associated complications. In the current study, we examined the scolicidal effects of gold nanoparticles on Echinococ...

Aim Fasciolosis and dicrocoeliosis are important parasitic diseases worldwide, causing significant financial losses due to decrease in production and viscera condemnation in animals. We performed the current research to assess the epidemiology of these infections and determine their significance from an economic perspective in Arak, Iran. Material...

The most important transmission path of intestinal parasites is the consumption of contaminated water and food. This survey was conducted to determine the prevalence of intestinal parasites among food handlers in Kashan, central Iran. This cross-sectional study was carried on 1018 food handlers who referred to the health centers in order to receive...

Background In Iran, both forms of cutaneous (CL) and visceral leishmaniasis (VL) have been reported; so the accurate species identification of the parasite(s) and the analysis of genetic diversity are necessary. Methods The smears were collected from lesions samples of 654 patients with CL, who attended local health centers in 12 provinces of Iran...

Neospora caninum and Toxoplasma gondii are two closely related protozoan parasites that have been detected from various species of bird hosts. However, little is known about the prevalence of N. caninum and T. gondii in crows. Hence, we examined the molecular frequency of N. caninum and T. gondii in the brain samples of hooded crows (Corvus cornix)...

Trichomoniasis, which is caused by Trichomonas vaginalis, is the most common non-viral sexually transmitted infection (STI) in the world including Iran. There were roughly 250 million new cases all over the world in a year. T. vaginalis as an important disease has been associated with HIV (in terms of exposure to sexually transmitted infection, STI...

Background: The protozoan Trichomonas vaginalis is a sexually transmitted disease (STD). Metronidazole is a chosen drug for the treatment. This study evaluated the anti trichomonal activity of alcoholic extracts of combination Verbascum thapsus and Ginger officinale. Methods: This experimental study was conducted in the Parasitology Laboratory, Ka...

The prevalence of bovine Sarcocystosis is high in the most regions of the world. It can be a human health problem due to consumption of raw or under cooked hamburgers or other bovine meat products. This study was carried out to investigate the prevalence and species identification of Sarcocystis among of hamburgers, using PCR–RFLP methods in Kashan...

Trichomonas vaginalis is a flagellated parasite affecting about 276 million people annually worldwide. Tricomoniasis is associated with different complications in pregnant women and infants. 5'-nitroimidazole derivatives (metronidazole, ornidazole, and tinidazole) are FDA approved drugs recommended for trichomoniasis treatment. Treatment with metro...

Background: Hydatidosis is one of the most important zoonotic parasitic disease worldwide caused by Echinococcus granulosus. Given the importance of parasite genotyping in disease control, this study was aimed to evaluate the genetic variation of the camel and dog isolates in Isfahan. Material and Methods: This cross-sectional study was done on inf...

Background: Based on genotyping study of human isolates of Giardia lamblia; humans are mainly infected by two assemblages A and B. The present study was carried out to determine the sub-assemblages of G. lamblia isolated from food handlers referred to Kashan health centers, central Iran, 2015. Methods: In this cross-sectional study, 3653 stool samp...

Background: Trichomoniasis is the most common sexually transmitted protozoan diseases in the worldwide. Metronidazole is the choice drug for trichomoniasis treatment, however, metronidazole resistant Trichomonas vaginalis (T.vaginalis) has been reported. Natural products are the source of most new drugs, and Zingiber officinale (Ginger) is widely u...

Little is known about latent infection and molecular characterisation of Neospora caninum in sheep (Ovis aries). In this study, 330 sheep samples (180 hearts and 150 brains) were analysed for N. caninum DNA by nested polymerase chain reaction (PCR) targeting the Nc-5 gene. Neospora caninum DNA was detected in 3.9% (13/330) of sheep samples. The par...

Background: Insecticide resistance is one of the serious problems for German cockroach control program. This study was conducted to determine the bendiocarb and Carbaryl resistance mechanisms in German cockroaches using the piperonyl butoxide (PBO). Methods: Bioassay tests were conducted with 4 to 6 different concentrations of both insecticides...

Background: There are scant evidences between giardiasis and enterobiasis with human mal-absorption of micronutrient. Objectives: The aim of the present study was to found out the changes in the serum zinc, copper, magnesium and vitamin B12 levels in schoolchildren infected with Giardia intestinalis and Enterobius vermicularis. Patients and Methods...

Trichomoniasis is a sexually transmitted disease (STD) caused by a tiny parasite called Trichomonas vaginalis. Metronidazole is used as routine treatment of disease. Some reports have confirmed the potential carcinogenic and teratogenic effects of this drug on fetus and indication of drug resistance. Verbascum thapsus belongs to the family of Scorp...

Trichomoniasis is a sexually transmitted disease (STD) caused by a tiny parasite called Trichomonas vaginalis. Metronidazole is used as routine treatment of disease. Some reports have confirmed the potential carcinogenic and teratogenic effects of this drug on fetus and indication of drug resistance. Verbascum thapsus belongs to the family of Scorp...

Neospora caninum is an intracellular protozoan parasite with a wide range of intermediate animal hosts. There is little information describing the prevalence and genetic characterization of N. caninum in bird hosts worldwide and in Iran. In this study, a total 217 brain samples of house sparrow (Passer domesticus) were examined for N. caninum prese...

Background: Treatment of cutaneous leishmaniasis with pentavalent antimony compounds, as an established drug, may have limitations, side effects and recurrence risk. For this reason, finding new and effective drugs is of great importance. In the present study, the effect of tamoxifen on the growth of Leishmania major promastigotes and amastigotes w...

Background: Treatment of cutaneous leishmaniasis with pentavalent antimony compounds, as an established drug, may have limitations, side effects and recurrence risk. For this reason, finding new and effective drugs is of great importance. In the present study, the effect of tamoxifen on the growth of Leishmania major promastigotes and amastigotes w...

Background: This study was conducted to determine acute and chronic toxoplamosis in pregnant women and its complications in newborn. Materials and Methods: In this cohort study, 798 pregnant women were tested for Toxoplasma IgG/ by ELISA. PCR and IgM were performed on 4 newborns of acute and 5 chronic maternal infections; were followed for 1 year....

Abstract: Background: Trichomoniasis is the most common sexually transmitted parasite in the world. The mainstay treatment for trichomoniasis is metronidazole, but some resistant strains to this treatment have also been detected. Considering the therapeutic properties of Pelarqonium roseum in traditional medicine, this study aimed to examine the an...

Objective: To determine the prevalence and economic losses of Fasciola spp. incurred due to liver condemnation from ruminants in Kashan region, center o fi sIroalant efrso amn d2 0c1o2s ttos 2013. Methods: In this cross-sectional study, a total number of 251 325 slaughtered sheep, goats and cinadttules tr(8ia8 l9 3K9a sshheaenp a, b1a5t1t o9i2r4s g...

Objective: To determine the prevalence and economic losses of Fasciola spp. isolates and costs incurred due to liver condemnation from ruminants in Kashan region, center of Iran from 2012 to 2013. Methods: In this cross-sectional study, a total number of 251 325 slaughtered sheep, goats and cattle (88 939 sheep, 151 924 goats and 10 462 cattle) wer...

Background: Trichomonas vaginalis infection is one of the most common sexually transmitted diseases in humans. T.vaginalis is a parasitic protozoan with a predilection for human urogenital tract and causative agent for vaginitis, cervicitis and urethritis in females. T.vaginalis infection is associated with risk of Human Immunodeficiency Virus infe...

Abstract Toxoplasmosis is one of the most common parasitic diseases worldwide. It is estimated that approximately one-third of the world's population is latently infected. Infection generally occurs via oral the route and maternal transmission. Damage of the central nervous system is one of the most serious consequences of congenital toxoplasmosis....

Objective: To determine the prevalence and economic losses of Fasciola spp. isolates and costs incurred due to liver condemnation from ruminants in Kashan region, center of Iran from 2012 to 2013. Methods: In this cross-sectional study, a total number of 251 325 slaughtered sheep, goats and cattle (88 939 sheep, 151 924 goats and 10 462 cattle)...

Toxoplasmosis is one of the most common parasitic diseases worldwide. It is estimated that approximately one-third of the world’s population is latently infected. Infection generally occurs via oral the route and maternal transmission. Damage of the central nervous system is one of the most serious consequences of congenital toxoplasmosis. Moreover...

Background: Entamoeba histolytica/Entamoeba dispar and Enterobius vermicularis are the major health problems in the developing countries especially in Iran. The prevalence of infection is variable among different social groups in the world. Objectives: Since elderly and mentally retarded are high risk group, the present survey was carried out in or...

Background: Entamoeba histolytica/Entamoeba dispar and Enterobius vermicularis are the major health problems in the developing countries especially in Iran. The prevalence of infection is variable among different social groups in the world. Objectives: Since elderly and mentally retarded are high risk group, the present survey was carried out in or...

Cutaneous leishmaniasis is still a health problem in many rural and urban regions of Iran and drug resistance has emerged as a major impediment in the treatment of leishmaniasis. This study aims to determine the drug resistance gene in cutaneous leishmaniasis by PCR in some endemic areas of Iran. Ninety seven samples were collected from ulcers of l...

Trichomoniasis is a worldwide protozoan parasitic disease and metronidazole is a choice drug for its treatment. Because of disease importance in public health and its controversial ideas about the prevalence of drug resistance, this study was carried out. Fifty-two suspected vaginal samples were collected from 2006 to 2007 in Gynecology Maryam Hosp...

Considering the role of parasites in contamination of human beings and domestic animals and lack of information in the region, the present study was performed to investigate the infection status of helminthes and protozoa of stray cats in central Iran. A cross - sectional study was conducted on 113 stray cats trapped from different geographic regio...

Introduction and objective: Toxoplasma gondii is a widespread protozoan parasite that infects human and animals. Tissue cyst of T. gondii is an important source of human and other hosts infection including cats as definitive host. This study was carried out to determine growth of T. gondii tissue cyst in laboratory syurian mouse. Materials and meth...

A r c h i v e o f S I D Iranian J Arthropod-Borne Dis, (2008), 2(2): 42-47 A Doroodgar et al: Treatment of Cutaneous Abstract Background: Considering the prevalence of leishmaniasis in Iran and many side effects associated with pentavalent antimony compounds use in its treatment, this study was designed to evaluate the effect of Artemisia sieberi e...

Background: Cat as definitive host of Toxoplasma gondii is important in the epidemiology of toxoplasmosis. The object of this study was to determine the seroprevalence of T. gondii as well as parasite isolation from faeces and brain tissues of stray cats in Kashan, central Iran. Methods: The prevalence of T. gondii was determined in serum, feces an...

Hydatidosis is one of the major zoonotic diseases that cause considerable economic losses and public health problems worldwide. The present study was conducted to determine the prevalence of E. granulosus in domestic and wild carnivores and the infection rate of hydatid cyst in slaughtered animals and people in Kashan area, central Iran. A total of...

Abstract: Background: Considering the roles of cockroaches in transmission and distribution of pathogen agents, their prevalence and lack of data on this kind of parasitic and fungal infections in this region, this study was carried out to determine the cockroaches species and their parasitic and fungal agents at the Hospitals of Kashan, Iran in 2...