Matthew Hodges

Eukaryotic cilia/flagella are ancient organelles with motility and sensory functions. Cilia display significant ultrastructural conservation where present across the eukaryotic phylogeny; however, diversity in ciliary biology exists and the ability to produce cilia has been lost independently on a number of occasions. Land plants provide an excelle...

Protein information and sequence identification for orthologous sets of each protein identified in the bioinformatic screen. Protein information shown is the annotation from the JGI database for Chlamydomonas reinhardtii. Apime = Apis mellifera, Cioin = Ciona intestinalis, Caeel = Caenorhabditis elegans, Cyame = Cyanidioschyzon merolae, Capsp = Cap...

mRNA Expression data for Arabidopsis thaliana mined from and used in analysis of CCP protein functions.

Protein information and sequence identification for ciliary profile proteins.

Protein information and sequence identification for CCP proteins.

Eukaryotic cilia are complex, highly conserved microtubule-based organelles with a broad phylogenetic distribution. Cilia were present in the last eukaryotic common ancestor and many proteins involved in cilia function have been conserved through eukaryotic diversification. However, cilia have also been lost multiple times in different lineages, wi...

Centrioles are highly conserved structures that fulfil important cellular functions, such as nucleation of cilia and flagella (basal-body function) and organisation of pericentriolar material to form the centrosome. The evolution of these functions can be inferred from the distribution of the molecular components of extant centrioles and centrosome...