Maria Elisa Galarraga-Vinueza

Tufts University | Tufts · Department of Prosthodontics and Operative Dentistry

Background Zirconia has emerged as a versatile dental material due to its excellent aesthetic outcomes such as color and opacity, unique mechanical properties that can mimic the appearance of natural teeth and decrease peri-implant inflammatory reactions. Objective The aim of this review was to critically explore the state of art of zirconia sur...

Background Different nonsurgical, antibacterial, surgical, and regenerative approaches to treat peri‐implantitis have been proposed, but there is no an actual “gold” standard treatment showing the most favorable results to counteract peri‐implantitis effects. Purpose To evaluate radiographically and clinically the disease resolution and peri‐impla...

Aim: To assess volumetric tissue changes at peri-implantitis sites following combined surgical therapy of peri-implantitis over a 6-month follow-up period. Materials and methods: Twenty patients (n = 28 implants) diagnosed with peri-implantitis underwent access flap surgery, implantoplasty at supracrestally or bucally exposed implant surfaces an...

Background and Objective Macrophages’ cytokine expression and polarization play a substantial role in the host's “destructive” inflammatory response to periodontal and peri‐implant pathogens. This study aimed to evaluate cell viability, anti‐inflammatory activity, and macrophage polarization properties of different cranberry concentrates. Methods...

Aim To apply high‐frequency ultrasound (HFUS) echo intensity for characterizing peri‐implant tissues at healthy and diseased sites and to investigate the possible ultrasonographic markers of health versus disease. Materials and Methods Sixty patients presenting 60 implants diagnosed as healthy ( N = 30) and peri‐implantitis ( N = 30) were assessed...

Background Peri‐implant disease prevalence is associated with a multifactorial etiology and distinct clinical characteristics of inflammation. Methods The present study aimed to assess the prevalence of peri‐implant diseases, identify related risk indicators, and associate specific clinical characteristics to peri‐implant biological complications...

Contemporary oral tissue engineering strategies involve recombinant human growth factor approaches to stimulate diverse cellular processes including cell differentiation, migration, recruitment, and proliferation at grafted areas. Recombinant human growth factor applications in oral hard and soft tissue regeneration have been progressively research...

Objectives: The aim of the present case series is to exhibit the long-term clinical and radiographic outcomes of resective surgery with adjunctive implantoplasty over a 6-to-11-year follow-up. Materials and methods: Four patients presenting 4 implants diagnosed with peri-implantitis according a to an established case definition were included in...

The cover image is based on the Review Article Soft tissue features of peri‐implant diseases and related treatment by Maria Elisa Galarraga‐Vinueza DDS et al., https://doi.org/10.1111/cid.13156 . image

Purpose: To describe a novel, noninvasive, intraoral optical scanning-based approach for characterising the buccolingual profile of peri-implant tissues using a 3D surface defect map. Materials and methods: Intraoral optical scans of 20 isolated dental implants with peri-implant soft tissue dehiscence in 20 subjects were captured. The digital mo...

Background: The need for soft tissue grafting at implant sites for preventing and treating peri-implant diseases is a currently investigated and debated topic. Purpose: The aim of this manuscript is to explore the inflammatory mechanisms at the peri-implant soft tissue compartment, to distinguish the structural components of the peri-implant sof...

Immediate implant placement with immediate restoration in the esthetic zone is a standardized protocol that aims to satisfy the patient with an immediate, esthetic rehabilitation. This study evaluated clinical and esthetic outcomes following immediate implant placement and provisionalization over a medium- to long-term period. A total of 57 implant...

Aim: To assess volumetric tissue changes following combined surgical therapy of peri-implantitis over a follow-up period of 24 months. Materials and methods: A total of 20 patients (n = 28 implants) were diagnosed with peri-implantitis and underwent access flap surgery, implantoplasty, and augmentative therapy at intrabony components (ie, combin...

Peri‐implantitis is caused by a bacterial challenge; therefore, anti‐infective treatment strategies should be employed to manage the disease. As nonsurgical approaches demonstrate limited efficacy in most cases of peri‐implantitis, surgical interventions are often required. Treatment outcomes improve following access flap surgery, with or without a...

Abstract Purpose To evaluate the influence of macrophage expression and polarization on the effectiveness of surgical therapy of peri-implantitis over a 6 month follow-up. Methods A total of fourteen patients (n = 14 implants) diagnosed with peri-implantitis underwent access flap surgery, granulation tissue removal, implantoplasty, and augmentation...

A importância da engenharia tecidual e o desenvolvimento de novos biomateriais para a substituição, preenchimento e reparo tecidual é indiscutível no campo da medicina. Os biomateriais aplicados na Implantologia devem ser biocompativeis a fim de que sua aplicação clínica seja previsível e não provoque sequelas ou riscos para a saúde do paciente. Al...

The objective of this study was to develop a replica method for producing zirconia-reinforced bioactive glass (ZRBG) porous structures for bone repair. Four different types of porous structures were produced: zirconia (G1), 58S BG-coated zirconia (G2), zirconia-reinforced BG (G3) and 58S BG-coated zirconia-reinforced BG (G4). A complete characteriz...

Objectives: To immunohistochemically characterize and correlate macrophage M1/M2 polarization status with disease severity at peri-implantitis sites. Materials and methods: A total of twenty patients (n = 20 implants) diagnosed with peri-implantitis (i.e., bleeding on probing with or without suppuration, probing depths ≥ 6 mm, and radiographic m...

Background: The social diversity, heterogeneous culture and inherent economic inequality factors in Latin America (LA) justify conducting a comprehensive analysis on the current status and future trends of peri-implant diseases and conditions. Thus, the aim of this Delphi study was to predict the future trends in the diagnosis and treatment of per...

Objectives To evaluate the prevalence of peri‐implant health, peri‐implant mucositis or peri‐implantitis for subcrestally placed implants (1‐3 mm) on the short‐, medium‐ and long‐term. Material & Methods Two hundred patients were enrolled in this cross‐sectional study that were treated and screened during regular maintenance visits at one universi...

Background To investigate the influence of soft-tissue volume grafting employing autogenous connective tissue graft (CTG) simultaneous to implant placement on peri-implant tissue health and stability. Material and methods This cross-sectional observational study enrolled 19 patients ( n = 29 implants) having dental implants placed with simultaneou...

Purpose: To assess the prevalence of peri-implant diseases (ie, peri-implant mucositis and peri-implantitis) in patients rehabilitated with full-arch, implant-supported restorations. Materials and methods: A search protocol was developed to answer the following focus question: What is the prevalence of peri-implant diseases in edentulous patient...

Background: To investigate the influence of lateral bone augmentation procedures performed simultaneously with implant placement on peri-implant health or disease. Material and methods: A total of 232 patients showing the same type of a two-piece implant placed either simultaneously with lateral bone grafting using a bovine bone mineral and a na...

Bone defects resulting from infections, tumors, or traumas represent a major-health care problem. There is a critical maximum size defect in which bone tissue can self-repair, so tissue engineering is often working in conjunction with medicine to develop techniques to repair bone damage and increase patient's life quality. In that context, scaffold...

Background To evaluate the prevalence of peri-implant disease after immediate implant placement and loading. Material and methods This cross-sectional analysis included a total of 47 patients with 64 implants exhibiting a mean loading time of 2 to 10 years (4.23 ± 1.7 years). The surgical and prosthetic procedures were standardized in all patients...

Nanostructured surfaces feature promising biological properties on biomaterials attracting large interest at basic research, implant industry development, and bioengineering applications. Thou, nanoscale interactions at a molecular and cellular level are not yet completely understood and its biological and clinical implications need to be further e...

Background: The present study aimed to assess the three-dimensional changes following soft tissue augmentation using free gingival grafts (FGG) at implant sites over a 3-month follow-up period. Methods: This study included 12 patients exhibiting deficient keratinized tissue (KT) width (i.e., <2 mm) at the vestibular aspect of 19 implants who und...

Introduction: The rehabilitation of a maxillary single dental implant represents a great challenge at clinical practice. Harmony among the implant-supported crown and adjacent teeth is required in which concerns pink and white aesthetics. The aim of the present case report is to depict a multidisciplinary treatment in which the U-shape flap techni...

Background: Inflammatory osteolysis is the clinical hallmark of peri-implantitis. The morphology of the remaining peri-implant bone and the level of osseointegration, however, remain unknown. Our aim was to characterize advanced peri-implantitis bone defects in humans. Methods: Four patients (3 female and 1 male) were diagnosed with peri-implant...

Implantoplasty has been claimed as a promising strategy to treat peri-implantitis and prevent progressive peri-implant bone loss. Consequently, the aim of the present case series is to exhibit the clinical outcomes of a 3-year-follow-up resective and implantoplasty therapy applying a novel platform-switch concept to preserve peri-implant tissue int...

Nanotechnology has emerged with novel nanostructured multifunctional biomaterials aiming to develop controlled delivery systems that can embed nano-sized bioactive molecules, which can promote desired biological responses at receptor sites through their nanotopographic and physiochemical properties. As follows, biomaterials like mesoporous ceramics...

The present chapter introduces the importance and concepts of nanostructured biomaterials and surfaces for oral and cranio-maxillofacial applications. A brief description is devoted on implant surfaces, bioactive ceramics, composites and functionally graded materials to bring readers with different backgrounds to a common level of knowledge. Keywo...

Bioactive glass is an attractive biomaterial that has shown excellent osteogenic and angiogenic effects for oral bone repairing procedures. However, anti-biofilm potential related to such biomaterial has not been completely validated, mainly against multispecies biofilms involved in early tissue infections. The aim of the present study was to evalu...

On the cover: Schematic diagram showing mesoporous bioactive glass loaded with antibacterial agents applied and delivered at infected implanted receptor sites with an acid medium to inhibit biofilm proliferation and repair bone defects.

Bioactive glasses (BGs) are promising materials for bone repair due to their desirable properties such as osteoconductivity, biodegradability, angiogenic potential, and antibacterial activity. Ionic dissolution products from bioactive glasses increase the medium pH reducing surrounding bacteria proliferation. The activity of BGs against biofilm for...

Background: Dimensional changes occur in the alveolar ridge after tooth loss due to bone resorption. Bioactive ceramic scaffolds have been developed for bone alveolar augmentation demonstrating desirable properties such as biocompatibility and osteocon-ductivity; however, their mechanical properties are still an issue during implantation.

Background: Mechanical factors in the rehabilitation with dental implants have to be taking into account in the treatment predictability. The extent of implant-supported prostheses is associated with a major biofilm accumulation that can induce an inflammation of the peri-implant tissues.

p>La periodontitis apical refractaria es una lesión periapical persistente en los tejidos perirradiculares de una pieza dental tratada con endodoncia. El origen infeccioso de la persistencia de las lesiones periapicales es un tema controversial y desafiante en odontología. El punto de vista tradicional sobre este tema defiende la escasa presencia o...