Mansour Karajibani

Zahedan University of Medical Sciences · Department of Nutrition, School of Medicine

Background Insulin resistance has been correlated with the genetic diversity within the insulin‐like binding proteins genes. Moreover, insulin resistance is one of the key characteristics of the widespread reproductive endocrine condition known as polycystic ovarian syndrome (PCOS). Hence, this study is aimed to determine the association between IG...

Background: Diabetes is the most common medical complication of pregnancy. Low serum zinc levels in pregnant women can cause uterine growth restriction and increase the risk of abortion and neural tube defects. Objectives: This study was designed to evaluate the association of serum zinc levels with gestational diabetes (GDM) in diabetic and health...

Background and aims: At present, the impact of the coronavirus disease pandemic on body mass index (BMI) and dietary patterns remains unknown properly. We aimed to identify an estimated 3 years trend in prevalence of overweight and obesity and food groups consumption variations among middle-aged population covered by health and treatment centers of...

Objective: Hypoxia-ischemia (HI) is one of the major disorders that causes a variety of abnormalities and infant mortality. Type 1 diabetes is one of the most common worldwide metabolic disorders, and its prevalence has become one of the public health concerns of the 21st century. This study aims to evaluate the effect of type 1 diabetes during pr...

Background: Abnormality in metabolism of lipids and hyperlipidemia is a risk factor for atherosclerosis which is the major cause of cardiovascular diseases (CVDs). Several herbal drugs are used for the treatment of dyslipidemia. The present study investigates the effects of hydroalcoholic extracts of Senna extract on serum lipid profile among hyper...

Background: The risk of bone fractures, particularly hip fractures is increasing in the elderly. One of the known factors for predicting fractures is body mass index (BMI) and abdominal obesity. Thus, this study aimed to determine the association between obesity (general and abdominal) with femoral and hip fractures according to gender and age. Met...

Aims Veterans may have improper eating behaviors and food habits. This study aimed to investigate the eating behaviors and food habits of veterans via the nutritional knowledge, attitude, and practices model in Zahedan City. Instruments & Methods In a descriptive, cross-sectional study, 369 veterans admitted to the Veterans Foundation in Zahedan we...

Background: Diabetes and obesity are associated with an increased risk of cardiovascular disease. Irisin is a newly recognized peptidic myokine with anti-obesity and anti-diabetic properties. This study aims to investigate the relationship between serum irisin levels with cardiometabolic biomarkers in patients with type 2 diabetes mellitus (T2DM)....

Introduction: Preeclampsia and eclampsia are pregnancy specific syndromes. Vitamin D is one of the pathological factors of this syndrome. The aim of this study was to compare the serum levels of vitamin D in pregnant women with preeclampsia or eclampsia with healthy pregnant women. Materials and Methods: In a cross-sectional, descriptive and analyt...

Purpose: There is little information about the association between zinc sulfate (ZnSO4) supplementation and metabolic profiles in zinc-deficient diabetic patients on hemodialysis (DHPs). Therefore, we aimed to investigate the association between ZnSO4 supplementation and serum levels of galectin-3 (Gal-3) and cardiometabolic parameters in zinc-def...

Maternal obesity and excessive gestational weight gain (EGWG) may have persistent effects on offspring obesity and be risk factors for both mother and child. Studies have reported that asprosin concentration is associated with metabolism and weight changes during pregnancy. This study therefore evaluated the association of maternal and newborn aspr...

Synbiotic supplementation can improve metabolic disorders. The aim of this study was to assess the impact of synbiotic supplementation on the levels of asprosin, lipid profile, glucose, and insulin resistance in pregnant rats fed a high-fat diet (HFD). Rats were divided into three groups: control group (fed base chow), HFD group, and HFD + synbioti...

We aimed to investigate the association between zinc (Zn) supplementation and serum levels of copeptin, high-sensitive C-reactive protein (hs-CRP), glycemic control, anthropometric parameters and renal function in Zn -deficient diabetic hemodialysis patients (DHPs). This randomized, double-blind, placebo-controlled trial (RCT) was conducted on 46 D...

Background Water pre-load affects insulin secretion by altering the level of copeptin (C-terminal component of the arginine vasopressin hormone (AVP)) and preventing obesity by reducing food intake.AimsThe present randomized controlled trial (RCT) aimed to investigate the effects of pre-meal water intake on type 2 diabetes Mellitus (T2DM).Materials...

Background: Opium addiction, as a major health problem, has been reported in Middle East countries. Recently, contaminated opium has been reported as a probable source of lead poisoning. Thus, the aim of this study is to evaluate blood lead levels (BLL), liver enzymes, and hemoglobin (Hb) concentrations in opium-dependent addicts with healthy cont...

Background: Malnutrition causes nutritional, metabolism, and biochemical disorders and finally leads to mortality. Several studies have highlighted that serum liver enzymes are increased in patients with malnutrition. Objectives: This study aimed to evaluate the relationship between malnutrition and liver enzymes in hospitalized children in Zahedan...

Introduction: Homocysteine (HCY), troponin, cardiac markers, folic acid and Vitamin B12 are known as the potential biomarkers for acute myocardial infarction (AMI) diagnosis. This study was designed to evaluate these markers as candidate biomarkers in the diagnosis, prognosis and prevention of AMI. Materials and Methods: This study was carried out...

Background: Caused by an imbalance in the body’s oxidant and antioxidant status, oxidative stress can give rise to tissue damage and exacerbation of many diseases. Objectives: This study investigated the oxidative stress markers in patients with fractures and healthy subjects. Methods: In a cross-sectional case-control study, 40 patients with fract...

Background: Metabolic syndrome (MetS) is closely related to the risk of cardiovascular disease (CVD), particularly in stressful occupations. Firefighting is a hazardous profession and is associated with high metabolic risk. However, limited studies on firefighters are available. Objectives: This study aimed to determine the prevalence of MetS among...

Objective Metabolic disorders during pregnancy have detrimental effect on mother and her fetus. Symbiotic supplementation can improve metabolic disorders. The aim of this study was to assess the impact of symbiotic supplementation on the levels of Chemerin, lipid profile, glucose, and insulin resistance in pregnant rats fed a high-fat diet (HFD)....

Background and aims: Obesity and hypertension are the major threats to health in a sedentary lifestyle and stressful jobs. The bank employees have sedentary jobs with high mental stress. The aim of this study was to determine the prevalence of hypertension and obesity and related factors among bank employees in Zahedan, located in Sistan and Baluch...

Background: Malnutrition, as a serious health problem in children, has an increasing prevalence in the developing countries. This study aimed to evaluate the anthropometric indices of primary school children in Iranshahr, a city in central region of Sistan and Baluchestan province, Iran. Methods: This cross-sectional study was conducted on a sample...

Background: Exercise training affects the adipose tissue, which may lead to the secretion of adipokines. This study aimed to evaluate the effect of endurance exercise training on vaspin, lipid profiles, and some anthropometric indices among young people. Methods: The participants included 26 young men selected and categorized into the intervention...

Background: The present study was carried out to enable, motivate, persuade, and assist the households to use their nutritional knowledge for the promotion of their nutritional status. Methods: In this descriptive- analytical study, 188 households were randomly selected from four regions, which were selected as the population lab in Zahedan city in...

Background and Objectives Gastro-esophageal reflux disease (GERD) is a common syndrome. Several factors are known with GERD, which lead to improvement in reactive oxygen species (ROS). The objective of this study was to determine pro-oxidant and antioxidant balance (PAB) in GERD patients in order to determine oxidative stress and the correlation be...

Background: There is evidence that oxidative stress can be considered as a critical event in the development of atherosclerotic complications. In this study, we aimed to assay the values of prooxidant-antioxidant balance (PAB) in patients with coronary artery disease (CAD), as a cardiovascular risk factor, and its relationship with some clinical, b...

Background Omentin-1, vaspin, and apelin are novel adipokines which closely associate with obesity, nonalcoholic fatty liver disease (NAFLD), and inflammation. The aim of this study was to investigate the circulating levels of omentin-1, vaspin, and apelin in NAFLD patients and to clarify their relationship with biochemical parameters, abdominal ob...

Background Metabolic syndrome (MetS) is a worldwide health problem, which is growing in Iranian adults. MetS is associated with risk of type 2 diabetes and coronary artery disease (CAD). In this study, we aimed to investigate the prevalence of MetS and its individual components in CAD patients. Methods This cross-sectional study was performed on 2...

Context: This study was a systematic review that aimed to extract published articles regarding oxidant and antioxidants status in opium addiction by searching in PubMed, Google Scholar engine, SID, and Magiran databases. Evidence Acquisition: Sixty-six published articles were investigated in this review, which were selected from studies among the I...

Background Clinical studies have demonstrated that adipocytokines play an important role in developing atherosclerotic cardiovascular diseases. Objective The aim of study was to evaluate the relationship between serum resistin and leptin levels with obesity and coronary artery disease (CAD). Methods In a cross-sectional study, we assessed the lev...

Background: Leptin is secreted by adipose tissue and decreases appetite. However, the role of leptin in the pathogenesis of hemodialysis (HD)-related malnutrition has not been fully evaluated. Objectives: The aim of study was to investigate the association between the serum leptin levels, serum C-reactive protein (CRP) levels, and nutritional st...

Background: There is evidence that hemodialysis (HD) leads to oxi-dative stress. However, reports about balance between oxidant and antioxidant are contradictory. Thus, the aim of this study was to evaluate the prooxidant-antioxidant balance (PAB) in HD patients and its correlation with clinical parameters and food intakes.

Prooxidant –antioxidant balance (PAB) is reported to be disturbed in diabetes patients. Adipose tissue represents an important source of reactive oxygen species (ROS). This study aimed to evaluate the changes prooxidant – antioxidant balance and its relationship with lipid profile and abdominal obesity in diabetic patients. Forty diabetes patients...

Food insecurity is a problem and has been contributed to nutritional status. The present study was designed to investigate the relationship between food insecurity and obesity among girl students, including obese and non-obese in Zahedan, southeast of Iran.Subjects were interviewed according to BMI, demographic data, information on household food i...

Introduction. A poor diet resulting from drug abuse has been reported in opiate-using populations. Substitution treatment with methadone has been used as one of the possible ways to prevent and control the drug abuse of opioid-dependent patients. The aim of the present study has been to evaluate the energy, micro- and macronutrient intakes of drug...

Objective. The aim of study was to investigate the changes levels of serum ghrelin in HD patients and its relationship to some malnutrition markers compared with healthy controls. Methods. Forty-five patients on hemodialysis and forty healthy controls were studied. Biochemical parameters and serum ghrelin levels were measured. Both daily dietary in...

Background: There are many factors which affect nutritional status of addicted such as lack o f knowledge, incorrect attitude toward modification of food pattern, and careless to food intake. Objectives: The aim of this study was to determine the effectiveness of educational program on nutritional behavior in addicts referring to Baharan hospital...

Background and Aims: In many drug abusers Methadone Maintenance Therapy (MMT) is accompanied by weight gain, changes in quality of diet, and improvement in hormonal disorders. The aim of this study was to evaluate serum leptin levels and their relationship with lipid profile and anthropometric parameters in addicts on MMT. Methods: Twenty-five drug...

Objective:To assess the dietary factors of Gastric Cancer (GC)in Zahedan, Iran. Methodology: 46 case GC and 46 healthy subjects participated in this case-control study. Food frequency questionnaire (FFQ) was used to determine the intake of different food groups. Besides food habits, cooking process and preparation of foods were recorded. The data w...

Objective: To assess of the fatty liver disease in obese adolescents in the southeast Iran. Methodology: We evaluated non alcoholic fatty liver disease (NAFLD) in 34 obese adolescents aged 11-19 years. Obesity was defined as body mass index (BMI) > 95 percentile adjusted forage and gender. Anthropometric measurements, blood pressure and biochemical...

Background: Adiponectin, an adipocyte-derived protein, modulates a number of metabolic processes. Methadone maintenance treatment (MMT) changes the level of hormones produced by adipose tissue in addicts. However, current data remains contradictory. Objectives: The aim of this study was to evaluate the effect of MMT on serum adiponectin levels i...

area. Materials and Methods: Two hundred samples of imported rice consisting; yellow (100) and white (100) rice were selected randomly. These samples were assessed for Aspergillus infection and the Aflatoxins B, G was detected by high performance liquid chromatography (HPLC) method. Results: The results showed, 33% and 47% of yellow and white rice...

Background: The present study was conducted in rural area of Sistan and Balouchistan province, south-east of Iran with aim of determine the prevalence of underweight, stunting, wasting, overweight and obesity among children. Materials and Methods: 1570 children were selected from all children less than 6 years covered by healthy and treatment cente...

Objective: In this study we investigated the effect of peritoneal dialysis (PD) on some antioxidant markers and lipid peroxidation. Methods: The levels of malondialdehyde (MDA), erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GPx), vitamins A, E, and C, and total antioxidant capacity (TAC) were determined in 23 chronic ambulatory PD...

Background Opium abuse significantly affects the nutritional status of users and frequently leads to undernourishment. Methadone maintenance therapy has been used as one of the possible ways to prevent of infection diseases such as HIV and hepatitis B and C and improve the quality of life in opioid-dependent patients. Objectives The aim of this st...

Background: The evidence suggests a relationship between lifestyle and diet-related risk factors. Objective: This study assessed the dietary intake and habits of high school girls in Sistan and Bluchistan province, in southeastern Iran. Methods: In a cross-sectional, descriptive study, 753 high school girls aged 14-18 years old were enrolled by a...

group Background: Drug addiction is a lifestyle disease. An assessment of the nutritional state of addicts is often done in parallel to their medical treatment. Objectives: The aim of the present study was to investigate the nutritional status of drug addicts. Patients and Methods: This study was conducted among 54 drug addicts (47 men and 7 women)...

Oxidative stress often occurs in chronic hemodialysis (HD). The aim of the present study was to determine plasma malondialdehyde (MDA) level for lipid peroxidation product and erythrocyte superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities as enzymatic antioxidants. Thirty-one HD patients (aged 50.3 ± 14.9 years) who were dialyze...

Objective To assess effects of vitamin E and C supplements on lipid profiles and antioxidant capacity in cardiovascular disease (CVD) patients. Subjects and Methods Forty CVD patients with age 57.7±10.6 years were selected to consume vitamin C and E daily for two months. Plasma lipid profile concentrations and antioxidant capacity were measured. Re...

There is some evidence showing an inverse correlation between dietary sources including natural antioxidant vitamins and the risk of cardiovascular disease (CVD). The aim of this study was to evaluate the effect of dietary antioxidants on oxidative stress in CVD patients. This study was carried out on 31 CVD patients and 63 healthy individuals. Nut...

Although hemodialysis (HD) is essential for end-stage renal disease patients, at the same time it causes oxidative stress and long-term pro-atherosclerotic effects. This study aimed to determine lipid profile as well as the total antioxidant capacity (TAC) and vitamins A, E, and C in HD patients. The study enrolled 31 patients (50.3 ± 14.9 years ol...

Oxidative stress plays an important role in the pathogenesis of cardiovascular disease (CVD). Growing evidence suggest that antioxidant vitamins might reduce the risk of disease outcomes by their ability to scavenge free radicals. The aim of the present study was to evaluate the supplementation of vitamins E and C on oxidant and antioxidant status...

Background Renal failure is accompanied by oxidative stress. An optimum intake of antioxidants is thought to be important to protect against oxidative damage. This study looked at the effects of dietary supplementation on antioxidant status and lipid peroxidation in hemodialysis patients. Methods During the study period, 34 patients who were under...

The aim of this study was to evaluate the antioxidant supplementation effect on antioxidant system in hemodialysis patients. The study group consisted of 38 patients undergoing hemodialysis and 72 healthy subjects. The patients orally received combination of vitamins C (250mg/time) and E (200IU/time) three times per week for 2months. Both, enzymati...

Objective: To evaluate the effect of vitamins C and E combined on lipid profile and total antioxidant capacity (TAC) in hemodialysis patients. Methods: A total of 38 hemodialysis patients received orally a combination of vitamin C (250 mg) and vitamin E (200 I.U) thrice a week for 2 months. Serum cholesterol, LDL, HDL and triglyceride and plasma TA...

Growing evidence has demonstrated that oxidative stress and increased altered oxygen utilization contribute to atherogenesis and cardiovascular disease (CVD) progression. Antioxidants protect the body from damage caused by free radicals. The objective of this study was to determine antioxidants status in CVD patients. This cross-sectional study was...

This descriptive study determined the prevalence of underweight, overweight and obesity among 752 high-school girls aged 14-18 years in Sistan va Baluchistan province, Islamic Republic of Iran. Using the Centers for Disease Control and Prevention body mass index percentiles, the prevalences of underweight, overweight and obesity were 16.2%, 8.6% an...