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Maha SellamiQatar University
Maha Sellami
PhD . Clinical Exercise Physiology
Exercise immunology & epigenetic control
Cancer & Bioenergetics
Diabetes
Aging population
About
63
Publications
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Introduction
Additional affiliations
January 2018 - present
Education
September 2017 - September 2018
January 2011 - January 2014
September 2007 - October 2009
Publications
Publications (63)
The use of herbal medicinal products and supplements has increased
during last decades. At present, some herbs are used to enhance muscle strength and body mass. Emergent evidence suggests that the health benefits from plants are attributed to their bioactive compounds such as Polyphenols, Terpenoids, and Alkaloids which have several physiological...
Immunosenescence is characterized by deterioration of the immune system caused by aging which induces changes to innate and adaptive immunity. Immunosenescence affects function and phenotype of immune cells, such as expression and function of receptors for immune cells which contributes to loss of immune function (chemotaxis, intracellular killing)...
Cancer represents a global health concern, imposing a severe burden both from a societal and clinical perspective. Despite the latest advancements and achievements in the treatment and management of malignancy, cancer still imposes a dramatically high burden worldwide. Different theories (biophysical or biochemical, genetic or epigenetic) related t...
The present contribution briefly overviews the major biological functions of the plasma membrane and of the transport proteins (transporters), which enable the movement of different molecules and substrates (either charged or uncharged) by passive (facilitated diffusion) or active transport. In particular, transporters are overviewed at the level o...
Horses (Equus ferus caballus) have evolved over the past 300 years in response to man‐made selection for particular athletic traits. Some of the selected traits were selected based on the size and horses’ muscular power (eg Clydesdales), whereas other breeds were bred for peak running performance (eg Thoroughbred and Arabian). Although the physiolo...
Aging is a fundamental biological process that progressively impairs the functionality of the bodily systems, leading to an increased risk of diseases. Telomere length is one of the most often used biomarkers of aging. Recent research has focused on developing interventions to mitigate the effects of aging and improve the quality of life. The objec...
Age-related differences in physical activity (PA), maturity status (PHV), physical performance (PP), and academic achievement (AA) among schoolchildren in Qatar were examined. Sixty-nine students from a school in Doha were categorized into three equal (n = 23) groups: 11-year-old students (U11; male: n = 14), 12-year-old students (U12: male: n = 7)...
Introduction
Physical activity-associated immune response plays a crucial role in the aging process. This study aimed to determine the impact of short-term moderate physical activity on cytokine levels, oxidative stress markers, and telomere length in lean/overweight young subjects.
Methods
Fasting blood samples were collected from 368 participant...
Physical activity (PA) is known to have beneficial effects on health, primarily through its antioxidative stress properties. However, the specific metabolic pathways that underlie these effects are not fully understood. This study aimed to investigate the metabolic pathways that are involved in the protective effects of moderate PA in non-obese and...
For a person with a disability, participating in sports activities and/or competitions can be a challenge for the immune system. The relationship between exercise and immunity response in disabled athletes is, indeed, extremely complex for several reasons, including (1) the chronic low-grade inflammatory and immunodepression-"secondary immune defic...
Healthy non-obese insulin resistant (IR) individuals are at higher risk of metabolic syndrome. The metabolic signature of the increased risk was previously determined. Physical activity can lower the risk of insulin resistance, but the underlying metabolic pathways remain to be determined. In this study, the common and unique metabolic signatures o...
Background:
Lipodystrophy is one of the most frequent complications in people with diabetes following subcutaneous insulin therapy, and poor management can lead to several problems, such as impaired glycemic control and adherence to therapy, anxiety, and depression. Poor injection technique represents the main risk factor for lipodystrophies. In o...
Introduction: The immunomodulatory effect of physical activity can impact insulin signaling differentially in adipose tissues and skeletal muscle cells, depending on sport intensity. In this study, the effect of serum from elite athletes with varying endurance levels and playing different power sports on cytokine secretion and insulin signaling in...
(1) Background: Young non-obese insulin-resistant (IR) individuals could be at risk of developing metabolic diseases including type 2 diabetes mellitus. The protective effect of physical activity in this apparently healthy group is expected but not well characterized. In this study, clinically relevant metabolic profiles were determined and compare...
Endurance training is associated with physiological changes in elite athletes, but little is known about female-specific effects of endurance training. Despite the significant rise in female sports participation, findings from studies performed on male athletes are largely extrapolated to females without taking into consideration sex-specific diffe...
Together with environment and experience (that is to say, diet and training), the biological and genetic make-up of an athlete plays a major role in exercise physiology. Sports genomics has shown, indeed, that some DNA single nucleotide polymorphisms (SNPs) can be associated with athlete performance and level (such as elite/world-class athletic sta...
Introduction: Biological aging is associated with changes in the metabolic pathways. Leukocyte telomere length (LTL) is a predictive marker of biological aging; however, the underlying metabolic pathways remain largely unknown. The aim of this study was to investigate the metabolic alterations and identify the metabolic predictors of LTL in elite m...
Introduction: Aerobic exercise activates the complement system in the peripheral blood. However, the effect of age and high intensity endurance training on the levels of circulating complements and sassociated inflammatory cytokines, oxidative stress markers and cellular aging remains unknown.
Methods: In this study, serum samples from 79 elite ath...
Exercise training is one of the few therapeutic interventions that improves health span by delaying the onset of age-related diseases and preventing early death. The length of telomeres, the 5′-TTAGGGⁿ-3′ tandem repeats at the ends of mammalian chromosomes, is one of the main indicators of biological age. Telomeres undergo shortening with each cell...
Telomeres protect genomic stability and shortening is one of the hallmarks of ageing. Telomerase reverse transcriptase (TERT) is the major protein component of telomerase, which elongates telomeres. Given that short telomeres are linked to a host of chronic diseases and the therapeutic potential of telomerase-based therapies as treatments and a str...
The possible influence of the quality of breathing on physical activity remains the subject of numerous scientific studies in different fields, including not only the most basic physiological and biological concepts but also the fields of psychiatry, psychology, and neuroscience. The literature about the relationship between breathing and psychophy...
Background:
Exercise-associated immune response plays a crucial role in the aging process. The aim of this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress markers and telomere length in aging elite athletes.
Methods:
In this study, 80 blood samples from consenting elite athletes were collected for anti-...
The level of immunoglobulins and cytokines changes with an ageing immune system. This review summarizes findings from studies that have examined the impact of acute and chronic exercise on immunoglobulins and cytokines in the elderly. Our literature analysis revealed that acute endurance exercise resulted in increased secretory salivary immunoglobu...
This second edition of Qatar National Physical Activity Guidelines is written as a practical guideline reference and not necessarily as a scientific resource. It outlines the most updated knowledge and best practices regarding physical activity as it relates to health. The intention of this content is to be an immediate and easy resource of informa...
This study examined the effects of home confinement on physical activity (PA) and life satisfaction during the COVID-19 outbreak in Qatar. A total of 1144 subjects participated (male: n = 588; female: n = 556; age: 33.1 ± 11.1 years; mass: 76.1 ± 16.4 kg; height: 1.70 ± 0.11 m; body mass index (BMI): 26.1 ± 4.44 kg/m2). Online survey questions cons...
This review aims to summarize the fundamental classes of antioxidants, the utilization of the supplement with antioxidants as ergogenic benefits in exercise and sport, the efficiency, and the consequence of their chronic uses. Antioxidants have been used for a long time in different sports disciplines and at all degrees of rivalry. The supplement w...
This study aimed to compare 10-to-12-year-old Qatari male athletes and assess body fat, body mass index, and physical fitness, as well as the difference of these measures between ages. Thirty-five youth handball players volunteered for the investigation and were divided into three groups: 12-year-old players (U12; n = 12), 11-year-old players (U11;...
Objectives
Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This study aims to compare the immune-inflammatory and oxidative stress profiles of elite athletes from different sport disciplines as potential biomarkers of muscle damage, and cardiovascular demand.
Methods
Serum samples from 88 consent...
Objectives: Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This study aims to compare the immune-inflammatory and oxidative stress profiles of elite athletes from different sport disciplines as potential biomarkers of muscle damage, and cardiovascular demand. Methods: Serum samples from 88 consen...
Proper nutrition plays a major role in preventing diseases and, therefore, nutritional interventions constitute crucial strategies in the field of Public Health. Nutrigenomics and nutriproteomics are arising from the integration of nutritional, genomics and proteomics specialties in the era of postgenomics medicine. In particular, nutrigenomics and...
Objectives
The study investigated the effect of combined sprint and resistance training (CSRT) on red blood cell (RBC) count, hemoglobin (Hb), hematocrit (Hct), plasma volume (PV) variation at rest and during exercise.
Equipment and methods
Twenty-eight moderately trained were randomly assigned into a young trained (YT), young control (YC), middle...
There is a positive association between physical activity (PA) and improved health in older adults. The objective of this study was to assess the prevalence and determinants of meeting recommended levels of PA among older adults with multimorbidity. Data has been derived from the nationally representative Scottish Health Surveys (2014–2017). A sub-...
The association between physical activity (PA) and mental well-being in individuals with a cardiovascular disease (CVD) is poorly studied. The objective of this study was to assess the association between mental well-being and adherence to the recommended guidelines for PA in a Scottish adult population with CVD. The study used data from 3128 adult...
This study investigated the effect of motor learning with informational feedback into response to anaerobic exercises with and without motor learning tasks in handball physical education university students. Participants were randomly divided into two groups: experimental group (EG, n = 10) and control group (CG, n = 10). Measurements of T-half tes...
Success in different soccer skills like kicking depends on motor abilities achieved. Kicking is a soccer fundamental, which depends on many different and complex factors (technique, football interaction, ball flight, etc.). Therefore, it is important to identify players that are able to perform faster kicks using both dominant and non-dominant leg....
Hormones are secreted in a circadian rhythm, but also follow larger-scale timetables, such as monthly (hormones of the menstrual cycle), seasonal (i.e., winter, summer), and, ultimately, lifespan-related patterns. Several contexts modulate their secretion, such as genetics, lifestyle, environment, diet, and exercise. They play significant roles in...
Several types of hormones exert control over appetite in humans. This narrative review explores the effects of exercise and training on the concentrations of gastrointestinal hormones in healthy and obese individuals. It focuses on the major hormones of appetite regulation: ghrelin, glucagon-like peptide 1, peptide YY, cholecystokinin, leptin, and...
Several classical dance complex movements, such as pointe, require body weight to be supported properly to avoid risk of foot injury. Regarding pointe shoes’ toe cap choice, it is unclear which type can better alleviate pain symptoms and toe deviation angle in dancers. The aim of the current crossover study was to investigate the acute effect of us...
Obesity is a medical condition that constitutes the major risk factor for the development of insulin resistance, type 2 diabetes and subsequent diabetes-related complications such as micro- and macrovascular disease [1, 2]. Chronic low grade inflammation has been described as a fundamental component of adipose tissue expansion in obesity. Inflamed...
Skin serves as the first protective line and barrier of the body. Like many other organs, skin can be affected by several disorders in response to external factors such as pathogens, ultraviolet light, and pollution, as well as endogenous alterations related to aging and/or oxidative stress disturbance. Researchers have reported new insights into h...
Aim: The purposes of this meta-analysis were to quantify the effectiveness of physical training on quality of life (QoL), aerobic capacity, and cardiac functioning in older patients with heart failure (HF) and evaluate dose–response relationships of training variables (frequency, volume, and duration).
Methods: Scholarly databases (e.g., PubMed/MED...
The purpose of the present investigation was to follow-up the effect of specific commandos' training-cycles (SCTCs) on upper-body strength resistance and running endurance performance , as well as determine whether variation in seasonal parameters has any effect on physical performance. Fourteen SCTCs were held over eight years, involving 466 parti...
Colour subdivisions of the shoe.
The image represents the exact subdivisions of the shoe. Red corresponds to the inside of the foot; yellow to the outside of the foot; blue to the neck of the foot; magenta to the heel; white to the tip of the foot; black to the sole.
(TIFF)
Receiving (A); passing (B); management (C); and shooting (D) tasks.
(TIFF)
Coach’s instructions for each test for BLACK group.
(DOCX)
Differences in scores and time for performance tests (reception, passing, management and shooting).
Data presented as mean (SD) and median (range). RECP–receiving test. PASS–passing test. MAGT–management test. SHOT–shooting test. COLOUR–experimental group. BLACK–control group, CI–confidence intervals, %chance–higher/similar/lower *p<0.05, **p<0.001...
The purpose of this research was to assess how the motor learning skills in 7-years old soccer players can be improved by preventing an internal focus of attention via the use coloured shoes. We painted the classic black soccer shoes in six areas corresponding to six regions of the foot with which it is possible to interact with the ball. Thirty-fo...
Total hip arthroplasty (THA) improve the patients’ quality of life, and one of the most important problems after surgery is to optimize postoperative pain management. It has been shown that pain is intimately linked to the fear of movement, the so-called kinesiophobia, which can affect the entire perioperative period and quality of life in people u...
The purpose of this study was to assess the logical and ecological validity of five explosive push-up variations as a means of upper-body power assessment, using the factorial characterization of ground reaction force-based (GRF-based) parameter outputs. Thirty-seven highly active commando soldiers (age: 23.3±1.5 years; body mass: 78.7±9.7 kg; body...
Cycling test such Wingate anaerobic test (WAnT) is used to measure anaerobic power (AP), but not anaerobic capacity (AC, i.e., the metabolic energy demand). However, in sports that do not involve cycling movements (Karate), the continuous jump for 30 s (vertical jumps for 30 s) has been extensively used to measure anaerobic performance in all young...
The aims of the present short review were to i) summarize data relating to the heart rate (HR) response to combat sports matches according to many factors and ii) determine the cardiovascular demand and intensity of combat sports matches. The present review shows that HR increased significantly across rounds during male taekwondo, boxing, and kickb...
Objective
This study examined the effect of 12-weeks of time-restricted feeding (TRF) on complete blood counts, natural killer cells (NKcells) and muscle performance in 20 and 50-year old men.
Research Methods & Procedures
Forty active and healthy participants were randomized into a young experimental (YE), a young control group (YC), an aged expe...
The aim of this investigation was to compare serum growth hormone (GH), insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) in response to a combined sprint and resistance training (CSRT) program in young and middle-aged men.Thirty-eight healthy, moderately trained men participated in this study. Young an...
Background: The aim of the present research was to study the effect of myrtle fruit (Myrtus Communis L.) supplementation on upper-body, lower-body strength and blood content in young men and women as well. METHODS: Thirty-two healthy, moderately trained athletes (20.2±0.8 years) participated in this study. They were randomly divided in four groups...
Objective:
To examine the effect of race differences on sprint performance, Hemoglobin (Hb), Hematocrit (Ht) and plasma volume (PV) variation in response to repeated sprint exercise.
Design:
Thirty-six healthy, moderately trained men and women (20.8 ± 0.2 year-old) volunteered to participate in this study. They were allocated to one of the four...
The aim of this study was to examine the effect of high-intensity sprint and strength training (HISST) on glucoregulatory hormones in young (20 years) and middle-aged (40 years) men. Thirty-six moderately trained men participated as volunteers in this study. After medical examination, eligible subjects were randomly assigned to one of four groups a...
The purpose of this research is to study the effects of aging and combined training (sprint and strength) on catecholamine responses [adrenaline (A) and noradrenaline (NA)].
Thirty-two male subjects voluntarily participated in this study. They were randomly divided into four groups: A young trained group (age 21.4 ± 1.2 years, YT, n = 8), a young c...