M. Yunus Bektay

İstanbul University-Cerrahpaşa · Clinical Pharmacy

Objective: Electrolyte disorder (ED) is frequently encountered critically ill patients during admission or admission to the intensive care unit (ICU). This study aimed to determine the frequency of ED encountered in ICU patients to evaluate the relationship of ED with drugs. Methods: This prospective, multicenter study was conducted in the medical...

Background: Antithrombotic drugs are frequently used in the Cardiology ward and patients receiving these drugs are thought to be vulnerable to drug-related problems (DRPs). The aim of this study was to evaluate clinical pharmacy services for the detection and prevention of DRPs in these patients. Methods: This prospective randomized controlled stud...

Chronic kidney disease (CKD) is a multifaceted disorder influenced by various factors. Drug–drug interactions (DDIs) present a notable risk factor for hospitalization among patients with CKD. This study aimed to assess the frequency and attributes of potential DDIs (pDDIs) in patients with CKD and to ascertain the concordance among different Clinic...

Objective: It is well-known that healthy medical students use psychostimulants to improve their cognitive functions and reduce their need for sleep. The main motivation behind this cognitive enhancement is to increase academic performance. However, the literature is not clear enough to support this situation. Methods: This cross-sectional study was...

Alzheimer's disease (AD) is a progressive neurodegenerative disorder impacting cognitive function and daily activities. Pharmacists' accessibility enables them to contribute to rational drug use, monitor interactions, and educate patients and ca-regivers, improving health outcomes. This study investigates pharmacists' knowledge of AD. A descriptive...

Objective: Over the past two decades, oral contraceptives have emerged as the predominant choice for contraception globally. This study explores women's knowledge, attitudes, and behaviors regarding oral contraceptives and the pharmacist's possible role. Material and Method: From November 2020 to January 2021, we conducted a cross-sectional obser...

Aim: Hypertension (HT) is a chronic disease characterised by high blood pressure and can cause many complications. Pharmacists can contribute to the quality of life and treatment success of HT patients with the pharmaceutical care service they provide. The aim of our study is to examine the effects of pharmaceutical care services provided by pharma...

Background: Although influenza is a contagious and widespread viral disease, its impact on public health is controlled by vaccination programs. However, anti-vaccination sentiment is also increasing in society. This study aims to explore the factors influencing influenza vaccine hesitancy. Methods: Between November 2020 and January 2021, a cross-se...

Objective: Mental illnesses constitute a significant contributor to the overall burden of illness, affecting a substantial number of individuals worldwide. The aim of the study is to to measure anxiety levels, along with a questionnaire to assess the pharmacist possible role in anxiety. Material and Method: A prospective study with onlineonline que...

Introduction: Alzheimer's disease (AD) is one of the pathologies that the scientific world is still desperate for. The aim of this study was the investigation of diazepam binding inhibitor (DBI) as a prognostic factor for AD prognosis. Methods: A total of 120 participants were divided into 3 groups. Forty new diagnosed Alzheimer patients (NDG) w...

COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are crit...

COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are crit...

COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are crit...

Objective: According to the World Health Organization (WHO), chest diseases are among the 10 diseases that cause the highest mortality worldwide. Drug-related problems (DRPs), readmission, and antimicrobial resistance are critical problems in chest disease wards. Active involvement of clinical pharmacists (CPs) who are focused on reducing the risks...

COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are crit...

COVID-19 has affected all aspects of human life so far. From the outset of the pandemic, preventing the spread of COVID-19 through the observance of health protocols, especially the use of sanitizers and disinfectants was given more attention. Despite the effectiveness of disinfection chemicals in controlling and preventing COVID-19, there are crit...

Objective:Clinical prognosis of coronavirus disease-19 (COVID-19) may be severe and unexpected. Patients may quickly progress to respiratory failure, infections, multiple organ dysfunction, and sepsis. The main objective of this study is to investigate the drug-related problems of patients with COVID-19 and related factors.Method:A prospective obse...

Introduction: One of the most intriguing situations for healthcare providers is cancer therapy. Drug–drug interactions (DDIs) account for 20–30% of all adverse effects. Cancer patients are more likely to have potential-DDIs since they are taking other drugs with anticancer treatments to prevent the side effects of chemotherapeutic agents. The purpo...

Objectives: One of the most common emergency surgery in pediatric surgery is due to acute appendicitis (AA). The diagnosis of AA is usuallymade using with the clinical score using clinical signs, symptoms, and laboratory tests. But symptoms and signs are not always typical, andthis situation put clinician in a compelling situation. The range of mis...

Background Pharmacists have been taking part in vaccination services during the COVID-19 pandemic. However, research identifying pharmacists’ intention to get COVID-19 vaccine is limited. Aim The objective of this study was to determine the intention to receive COVID-19 vaccine and to identify the factors related to it based on the Health Belief Mo...

Alzheimer’s disease (AD), is characterized by its progressive feature and loss of cognitive functions, is common among dementia types. There is no curative treatment of the disease today. In recent years, transcranial magnetic stimulation (TMS) techniques together with drug therapy have been explored by experts considering that they will produce be...

Objective The objectives of this study were to identify community pharmacist (CP)-led cognitive services and CPs’ precautions taken related to COVID-19, perceived enablers and barriers related to pharmaceutical services, and burnout levels during the COVID-19 pandemic. Method In this descriptive study, the survey was administered online to CPs in...

Introduction The use of psychostimulant drugs to increase academic success is common among young people. There is no study examining this issue in Turkish population. In this study, the prevalence, attitudes, knowledge and ethical evaluations of Pharmacological Cognitive Enhancement (PCE) in university students were investigated. Method A structur...

Objective:This study aimed to evaluate the reliability of the High- Alert Medications (HAM) Questionnaire in Turkish healthcare professionals.Methods:This methodological study was conducted between December 2017 and January 2018 in a private university hospital. The healthcare professionals, including nurses, health service technicians, and pharmac...

Objectives: Hepatocellular carcinoma (HCC) is the seventh most common cancer and the third leading cause of tumor-related deaths worldwide. Mechanisms underlying tumor onset, progression, and metastasis in the case of HCC have not been adequately studied. In this study, we aimed to investigate the genotoxic, cytotoxic, apoptotic and oxidant effect...

Background: Alzheimer’s Disease (AD) is a major concern in growing chronic diseases in the geriatric society and its connection with polypharmacy has not been sufficiently understood. Aim: This Study investigate the association between Alzheimer’s disease and polypharmacy. Methods: A prospective cohort study. Patients with diagnosis of the AD and b...

Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive neuromodulation technique which is increasingly used for cognitive impairment in Alzheimer’s Disease (AD). Although rTMS has been shown to modify Brain-Derived Neurotrophic Factor (BDNF) and oxidative stress levels in many neurological and psychiatric diseases, there is still no...

The new type of Coronavirus (SARS-CoV-2) is a highly contagious pathogen that causes severe acute respiratory syndrome and can be transmitted from human to human. COVID-19, which has been declared as a pandemic by the world health organization and is infected with more than 50 million people, is also responsible for the death of more than 1 million...

Background: The widespread use of synthetic cannabinoids (SCs) among youth has become an important public health problem. Several life-threatening side effects of SC have been reported, including cardiovascular, gastrointestinal, neurological, renal, metabolic, ophthalmologic, and pulmonary effects, besides skin toxicity and hepatotoxicity. Methods...

The practice of clinical pharmacy had a positive impact on the profession by giving pharmacists more job opportunities. Moreover, the pharmacy began to gain the status it deserved, which was lost many years ago. In this paper, we aimed to give a brief explanation of the clinical pharmacy philosophy and definition of pharmaceutical care. What are th...

Mutations in genes encoding the formation of ion channels may cause epileptic syndromes. These epileptic syndromes are generally divided into generalized and partial epilepsies. Among the causative agents of generalized epilepsy showing mendelian or non-mendelian inheritance; mutations in sodium channel, calcium channel, GABAA receptor and nicotini...

Background The most common type of dementia is an Alzheimer’s disease which is a major concern in growing chronic diseases in the geriatric society, and its connection with biochemistry has not been sufficiently understood. Objective This study aims to evaluate the effects of blood biochemistry on Alzheimer’s disease. Method Eight participants ag...

Background and Objective: Cancer treatment is one the most compelling situation for healthcare providers. The situation itself already complicated enough. In addition, cancer treatment requires multiple medication usage simultaneously. Drug-drug interactions (DDI) compose 20-30% of adverse effects. Drug-drug interactions are responsible 4% of morta...

Background and Objective: Cancer treatment is one the most compelling situation for healthcare providers. The situation itself already complicated enough. In addition, cancer treatment requires multiple medication usage simultaneously. Drug-drug interactions (DDI) compose 20-30% of adverse effects. Drug-drug interactions are responsible 4% of morta...

In this study, mixed-structure carbon–magnetite nanocomposites were prepared by decorating of carbon nanofiber (CNF) surfaces with magnetite (Fe3O4) nanoparticles synthesized via reflux method and characterized. The compositions of CNF–Fe3O4 nanocomposites were varied using different amounts of CNF into the Fe3O4 synthesis medium as 25/75, 50/50, a...

Olive (Olea europaea L.) is one of the oldest fruit and beverage of human kind. In ancient times usage of olive has been found especially around Neolithic settlements. Olive oil used for decades with different purposes. Medical uses for olive oil is pretty abundant especially among Mediterranean folks. Due to high amounts of consumption cultivation...

Rosemary (Rosmarinus officinalis) is an evergreen shrub nearly grown all soils of earth. Historical and common use of this herb is pretty frequent among people of earth. Especially Mediterranean cuisine often use rosemary as food substituents, medical plant, and spice. Leaves and stems are medicinal part of rosemary and contains numerous biological...

In this study, graphene nano sheets, prepared with chemical oxidation and reduction route via modified Hummer method, were successfully decorated with platinum (Pt) and palladium (Pd) nanoparticles. Structural and morphological features of resulted graphene-metal nanocomposites were characterized with FT-IR, XRD, SEM and TEM methods. It was found...

Plants contain a large amount of structurally diverse chemical compounds. Medicinal plants are important source to invent potential drugs and safe antioxidant compounds. Salvia species are remarkable to scientists for their biologically active constituents and they have been used as folkloric plants since ancient times. The genus Salvia is the larg...

Ulcerative colitis (UC) is a common, relapsing inflammatory bowel disease (IBD) presents with ulcers and wounds located on colonic intestinal mucosa. The difference between ulcerative colitis and Crohn’s disease is that ulcerative colitis located on colon and wounds are limited superficial mucosal membranes of intestinal lumen. Main pathological fe...

Migraine is a common, neurovascular disorder characterized by severe repeated headaches. Dysfunction of autonomic systems and auras are involved in it is patophysiology. Migraine has affecting great number of individuals in population; prevelance of disease is about 10-15 %. However the exact mechanism of action of migraine is not well understood,...