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Publications (62)
An X-ray phosphor screen is a standard component at beamlines of Taiwan Photon Source (TPS). It responds to x-rays, re-emitting the energy as visible light. This screen is used as a tool for the coarse alignment of the synchrotron beam. The development of TPS beamlines proceeds to Phase III. Based on the user feedback of Phases I and II, we redesig...
Background and purpose:
Graph theory uses structural similarity to analyze cortical structural connectivity. We used a voxel-based definition of cortical covariance networks to quantify and assess the relationship of network characteristics to cognition in a cohort of patients with relapsing-remitting MS with and without cognitive impairment.
Mat...
UHV precision mono-beam slits are being designed and used at Taiwan Photon Source (TPS) beamlines in the National Synchrotron Radiation Research Center (NSRRC). The slits serve to shape the beam sizes and simultaneously to act as monitors of the position of the photon beam (PBPM). The main features of the slit system are the compact and robust cham...
The screen system described in this article is designed to meet the needs of a synchrotron radiation beamline at Taiwan Photon Source (TPS). In the design of the mechanical structure, we combined a square chamber and a coaxial cooling tube for spatial efficiency. The coaxial cooling tube with a fluorescent plate is controlled with a cylinder or mot...
Background and purpose:
The spatial correlation between WM and cortical GM disease in multiple sclerosis is controversial and has not been previously assessed with perfusion MR imaging. We sought to determine the nature of association between lobar WM, cortical GM, volume and perfusion.
Materials and methods:
Nineteen individuals with secondary-...
A digital autocollimator of resolution 0.1 µrad (0.02 arcsec) serves as a handy correction tool for calibrating the angular uncertainty during angular and lateral movements of gratings inside a monochromator chamber under ultra-high vacuum. The photon energy dispersed from the extreme ultraviolet (XUV) to the soft X-ray region of the synchrotron be...
Background and purpose:
Cortical dysfunction, quantifiable by cerebral perfusion techniques, is prevalent in patients with MS, contributing to cognitive impairment. We sought to localize perfusion distribution differences in patients with relapsing-remitting MS with and without cognitive impairment and healthy controls.
Materials and methods:
Th...
During the last 20 years, beamline BL08B has been upgraded step by step from a photon beam-position monitor (BPM) to a testing beamline and a single-grating beamline that enables experiments to record X-ray photo-emission spectra (XPS) and X-ray absorption spectra (XAS) for research in solar physics, organic semiconductor materials and spinel oxide...
Cognitive impairment is a common, disabling symptom of MS. We investigated the association between cognitive impairment and WM dysfunction in secondary-progressive multiple sclerosis using DTI.
Cognitive performance was assessed with a standard neuropsychological battery, the Minimal Assessment of Cognitive Function in Multiple Sclerosis. Cognitive...
Sequences were screened for chimeras by the submitter using EzTaxon-e Beta. ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using EzTaxon-e Beta. ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using EzTaxon-e Beta. ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using ETaxon-e Beta. ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using ETaxon-e Beta. ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
Sequences were screened for chimeras by the submitter using ETaxon-e Beta. ##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
##Assembly-Data-START## Sequencing Technology :: Sanger dideoxy sequencing ##Assembly-Data-END##
Background and purpose:
Cognitive impairment is a common, disabling symptom of MS. We investigated the impact of cerebral perfusion and brain and lesion volumetry on cognitive performance in 45 patients with SPMS by using MR imaging.
Materials and methods:
Cognition was assessed by using a standard battery, the Minimal Assessment of Cognitive Fu...
There is increasing evidence implicating microvascular impairment in MS pathogenesis. Perfusion imaging offers a unique opportunity to investigate the functional impact of GM pathology. We sought to quantify differences in MR imaging-based bookend-derived cerebral perfusion between cognitively impaired and nonimpaired patients with SPMS.
Patients w...
Purpose: Currently, there are two types of treatment planning algorithms for intensity modulated radiation therapy (IMRT). The beamlet‐based algorithm generates fluence maps with high complexity, resulting in large numbers of segments in the delivery. The segment‐based direct aperture optimization (DAO) algorithm uses a small number of segments. Ho...
Purpose: To develop a methodology for retrospectively reconstructing the dose delivered to head‐and‐neck (HN) patients in RapidArc treatment based on dynamic log‐files which record the actual leaf positions, gantry angles, and delivered monitor units (MUs) during the RapidArc delivery. Method and Materials: After a RapidArc treatment was finished,...
Nowadays magnetic resonance imaging (MRI) has been profoundly used in radiotherapy (RT) planning to aid the contouring of targets and critical organs in brain and intracranial cases, which is attributable to its excellent soft tissue contrast and multi-planar imaging capability. However, the lack of electron density information in MRI, together wit...
The electronic structure of the magnetic semiconductor Ga1−xCrxN, and the effect of Si doping on it have been investigated by photoemission and soft x-ray absorption spectroscopy. We have confirmed that Cr in GaN is predominantly trivalent when substituting for Ga and that Cr 3d states appear within the band gap of GaN just above the N 2p-derived v...
The electronic structure of the Cr ions in the diluted ferromagnetic semiconductor Zn1-xCrxTe (x=0.03 and 0.15) thin films has been investigated using x-ray magnetic circular dichroism (XMCD) and photoemission spectroscopy (PES). Magnetic-field (H) and temperature (T) dependences of the Cr 2p XMCD spectra correspond well to the magnetization measur...
Breast cancer gene 1 (BRCA1) mutations predispose women to breast and ovarian cancers and men to increased risks for prostate cancer. We have previously showed BRCA1 splice variant BRCA1a/p110 to induce apoptosis of human breast cancer cells. In the current study, stable expression of BRCA1a/p110 resulted in inhibition of growth of estrogen recepto...
The electronic structure of the Cr ions in Zn1−x
Cr
x
Te (x=0.03 and 0.15) has been investigated using X-ray magnetic circular dichroism (XMCD) and photoemission spectroscopy. Magnetic-field
(H) and temperature (T) dependences of the Cr L
2,3 XMCD spectra well corresponded to the behavior of the magnetization measured by a SQUID magnetometer. The l...
Rheumatoid arthritis is a severe inflammatory disease affecting 1-2 per cent of the population, leading to significant morbidity and mortality. The exact aetiopathogenesis is not known, but is believed to be predominantly T cell mediated in genetically-susceptible individuals. Conventional treatment has been helpful, but unable to prevent ongoing i...
Molecular characterization of malignant melanoma of soft parts or soft tissue clear cell sarcoma which shares t(12;22) chromosome translocation revealed fusion of EWS with a transcriptional factor gene ATF-1. The EWS gene, which encodes an RNA binding protein, was also shown to be involved in Ewing sarcoma, related primitive neuroectodermal tumors...
EWS and TLS/FUS genes, which code for RNA binding proteins are involved in a wide variety of human solid tumors. The TLS/FUS gene is involved both in human myxoid liposarcomas which carry a characteristic chromosomal translocation, t(12;16)(q13;p11) and in human myeloid leukemias with recurrent chromosomal translocation, t(16;21)(p11:q22). The TLS/...
The EWS gene, which maps to band q12 of human chromosome 22, is involved in a wide variety of human solid tumors including Ewing sarcoma, related primitive neuroectodermal tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors. In these tumors, the EWS is fused to genes encoding transcriptional activators/repressors, like...
ets oncogene superfamily consists of a family of transcriptional factors that functions as activators and/or repressors. Previously, we have identified a member of this ets superfamily namely erg, ets related gene. erg gene was shown to code for at least two proteins erg-1 and erg-2 because of alternative splicing and alternative usage of initiatio...
elk-1, an ets related gene codes for a sequence specific DNA binding transcriptional activator which in association with serum response factor (SRF) forms a ternary complex at the c-fos serum response element (SRE). Recently the C-terminal region of both elk-1 and delta elk-1 proteins was shown to undergo phosphorylation by MAP kinases and function...
erg, an ets related gene encodes a sequence specific DNA binding transcriptional activator protein. We have identified four functional domains of erg protein that are responsible for DNA binding, transcriptional activation and negative regulation of transcriptional activation. Deletion analysis revealed that the 3'-ets domain of the erg protein is...
A language for specifying the data acquisition and initial-event rejection requirements of experiments using the TRIUMF VAX-based CAMAC data acquisition system has been designed and implemented. Terse, low-level, assembler-like syntax was rejected in favor of a form more familiar to physicists, namely Fortran. The language, known as Twotran, is an...
The new TRIUMF VAX-based DAAS requires data to be exchanged between acquisition, monitoring and analysis processes executing on a VAX. Data records are passed via a set of buffers contained in a region of memory shared by all processes. The responsibility for buffer management is distributed among the processes and synchronized access to the region...
The requirements of fast graphics display and low impact on the data acquisition and analysis system (DAAS) VAX host prompted TRIUMF to adopt PC's on an ethernet as graphics workstations for the new VAX-based DAAS. This multiprocessor solution provides for high speed host to workstation data transfer for image display, and independence of the host'...
An upgrade program on TRIUMF's PDP-11 hosted CAMAC-based data acquisition systems has begun. The new analysis and control hosts are to be VAXs interfaced to CAMAC by the HYTEC System Crate Architecture. The CES ACC 2180 STARBURST is to be the front-end processor, off-loading the handling of real-time events from the VAX. The hardware arrangement an...
A contemporary system building design notation was adopted for the engineering of TRIUMF's new VAX-based data acquisition and analysis system. The requirements of automated systems' design notations are discussed and the elements of the chosen notation described. Finally the group's experience in designing a data acquisition system with these techn...
Der Brückenligand wurde aus dem entsprechenden Diiododerivat durch Reaktion mit CuCN in N-Methylpyrrolidinon unter Rückfluß mit 53% Ausb. oder nach einer Literaturmethode dargestellt.
The photochemistry of cis-L-Rh(en)â(HâO)(OH)/sup 2 +/ and cis-L-Rh(en)â(OH)â/sup +/ in aqueous solution is reported. Irradiation at 313 nm results in a photoracemization quantum yield of 0.05 +/- 0.01 and 0.008 +/- 0.002 mol/einstein, respectively. The results of this work and previous studies on the photochemistry of cis- and trans-Rh(en)â(OH)X/su...
Bestrahlung der Komplexe (I), die hochgradig absorbierende Metall-zu-Ligandiadungs?bertragungs-Banden im sichtbaren Spektralbereich zeigen, f?hrt im allgemeinen zur Spaltung der M?-L- oder L-Mz-Bindung.
Die Metall-zu-Ligand-Ladungsübertragungs-Banden in den Komplexen (I) sind mit den A′ Gruppierungen assoziiert.
Die heterometallischen Zweikernkomplexe (III) und (V) werden durch l zl-molare Umsetzung der Rh(III)- und Co(IIII)-Komplexe (II) bzw. (IV) mit dem aus dem Pentaeyanoamminferrat (I) gebildeten Aquo- Derivat in situ synthetisiert.
